Medizininformatik Initiative - ImplementationGuide - Modul PRO v2026

PROMIS-16 Profile v2.1 (PROPr)

Übersicht

Status: Implementiert — alle 16 Items, ohne Score-Berechnung
Version: 2026.5.0
Letzte Aktualisierung: 2026-06-10

Der PROMIS-16 Profile v2.1 (PROPr) ist ein ultrakurzes Multi-Domain-Instrument zur Erfassung der gesundheitsbezogenen Lebensqualität (HRQoL) mit nur 16 Items über 8 Domänen (je 2 Items pro Domäne). Es eignet sich für Settings mit hoher Erhebungslast wie wiederholte Verlaufsmessungen oder Screening.

Quelle: Edelen et al. 2024 -- PROMIS®-16: development and preliminary psychometric evaluation (Qual Life Res, doi:10.1007/s11136-023-03597-6)

Ressourcen in Simplifier:

PROMIS-16 Questionnaire

Questionnaire

id : mii-qst-pro-promis-16

meta

profile : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/StructureDefinition/mii-pr-pro-questionnaire|2027.0.0-ballot.1

language : en

extension

url : http://hl7.org/fhir/StructureDefinition/artifact-versionAlgorithm

value

system : http://hl7.org/fhir/version-algorithm

code : natural

display : Natural

extension

url : displayable

value : True

extension

url : collectable

value : True

extension

url : calculatable

value : False

extension

url : extractable

value : True

extension

url : domainAligned

value : True

url : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/StructureDefinition/mii-ex-pro-questionnaire-capabilities

url : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/Questionnaire/mii-qst-pro-promis-16

version : 2027.0.0-ballot.1

title : MII QST PRO PROMIS-16 (Adults)

status : draft

experimental : True

publisher : Medizininformatik-Initiative (MII) – PRO Modul

contact

name : PROMIS National Center Deutschland (CPCOR)

telecom

system : url

value : https://cpcor.charite.de/promis_national_center_deutschland/nutzungsanfragen

description : PROMIS-16 Profile v1.0 - Ultra-short 16-item HRQoL Profile across 8 domains (Edelen et al. 2024, doi:10.1007/s11136-023-03597-6). T-score calculation per Supplement S4 is delegated to a CQL Library (see roadmap 2027).

useContext

code

system : http://terminology.hl7.org/CodeSystem/usage-context-type

code : focus

value

display : PROMIS (Patient-Reported Outcomes Measurement Information System) (https://www.healthmeasures.net/explore-measurement-systems/promis)

useContext

code

system : http://terminology.hl7.org/CodeSystem/usage-context-type

code : focus

value

display : PROMIS National Center Deutschland (CPCOR Charité) — Curator of the official German translations provided by PCOR-MII (https://cpcor.charite.de/promis_national_center_deutschland)

useContext

code

system : http://terminology.hl7.org/CodeSystem/usage-context-type

code : focus

value

display : PROMIS-16 Profile (Edelen et al. 2024, Qual Life Res) (https://doi.org/10.1007/s11136-023-03597-6)

copyright : The FHIR Questionnaire resource (linkIds, extensions, score calculation logic, observation extraction definitions) is part of the MII PRO Module and is licensed under CC-BY 4.0. The PROMIS items contained herein (item text, response options, scoring algorithms, IRT parameters) are © 2008–2024 PROMIS Health Organization and PROMIS Cooperative Group. PROMIS® is a registered trademark. See https://www.healthmeasures.net for the upstream license. The official German translations are provided by PCOR-MII (Patient-Centered Outcomes Research within the Medizininformatik-Initiative) and curated by the PROMIS National Center Germany (CPCOR, Charité – Universitätsmedizin Berlin; head: Felix Fischer). Institutional use outside the PCOR-MII / MII context requires a usage request to CPCOR: https://cpcor.charite.de/promis_national_center_deutschland/nutzungsanfragen LOINC® codes are © Regenstrief Institute, Inc. and used under the LOINC license: https://loinc.org/license/

code

system : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/CodeSystem/mii-cs-pro-questionnaire-catalogue

code : promis-promis16

display : PROMIS-16 Profile Questionnaire (ultra-short 8-domain profile)

item

linkId : PROMIS-16.PhysicalFunction

text : Physical Function

extension

url : lang

value : de

extension

url : content

value : Körperliche Funktion

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-pfa21

code

system : http://loinc.org

code : 62826-3

display : Are you able to go up and down stairs at a normal pace [PROMIS]

text : Are you able to go up and down stairs at a normal pace?

extension

url : lang

value : de

extension

url : content

value : Können Sie mit normaler Geschwindigkeit Treppen hoch- und runtergehen?

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-physical-function-response-scale

item

linkId : promis-pfa23

code

system : http://loinc.org

code : 62827-1

display : Are you able to go for a walk of at least 15 minutes [PROMIS]

text : Are you able to go for a walk of at least 15 minutes?

extension

url : lang

value : de

extension

url : content

value : Können Sie mindestens 15 Minuten lang spazieren gehen?

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-physical-function-response-scale

item

linkId : PROMIS-16.Anxiety

text : Emotional Distress — Anxiety

extension

url : lang

value : de

extension

url : content

value : Emotionale Belastung — Angst

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-edanx40

code

system : http://loinc.org

code : 61941-1

display : I found it hard to focus on anything other than my anxiety in past 7 days

text : I found it hard to focus on anything other than my anxiety.

extension

url : lang

value : de

extension

url : content

value : Ich fand es schwer, auf etwas anderes zu achten als auf meine Angst.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : promis-edanx41

code

system : http://loinc.org

code : 61942-9

display : My worries overwhelmed me in past 7 days

text : My worries overwhelmed me.

extension

url : lang

value : de

extension

url : content

value : Meine Sorgen haben mich überwältigt.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : PROMIS-16.Depression

text : Emotional Distress — Depression

extension

url : lang

value : de

extension

url : content

value : Emotionale Belastung — Depressivität

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-eddep29

code

system : http://loinc.org

code : 61967-6

display : I felt depressed in past 7 days [PROMIS]

text : I felt depressed.

extension

url : lang

value : de

extension

url : content

value : Ich fühlte mich niedergeschlagen.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : promis-eddep41

code

system : http://loinc.org

code : 61973-4

display : I felt hopeless in past 7 days [PROMIS]

text : I felt hopeless.

extension

url : lang

value : de

extension

url : content

value : Ich fühlte mich hoffnungslos.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : PROMIS-16.Fatigue

text : Fatigue

extension

url : lang

value : de

extension

url : content

value : Erschöpfung

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-hi7

code

system : http://loinc.org

code : 61878-5

display : I feel fatigued during the past 7 days [PROMIS]

text : I feel fatigued.

extension

url : lang

value : de

extension

url : content

value : Ich bin erschöpft.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

item

linkId : promis-an3

code

system : http://loinc.org

code : 61882-7

display : I had trouble starting things because I was tired in past 7 days [PROMIS]

text : I had trouble starting things because I was tired.

extension

url : lang

value : de

extension

url : content

value : Es fällt mir schwer, etwas anzufangen, weil ich müde bin.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

item

linkId : PROMIS-16.Sleep

text : Sleep-related Impairment / Sleep Disturbance

extension

url : lang

value : de

extension

url : content

value : Schlafbezogene Beeinträchtigungen / Schlafbeeinträchtigung

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-sleep25

text : I had problems during the day because of poor sleep.

extension

url : lang

value : de

extension

url : content

value : Ich hatte tagsüber Probleme, weil ich schlecht geschlafen habe.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

item

linkId : promis-sleep90

text : I had trouble sleeping.

extension

url : lang

value : de

extension

url : content

value : Es fiel mir schwer zu schlafen.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : PROMIS-16.SocialRoles

text : Ability to Participate in Social Roles and Activities

extension

url : lang

value : de

extension

url : content

value : Teilhabe an sozialen Rollen und Aktivitäten

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-srpper31-caps

text : I have trouble taking care of my regular personal responsibilities.

extension

url : lang

value : de

extension

url : content

value : Es fällt mir schwer, mich um meine regelmäßigen persönlichen Verpflichtungen zu kümmern.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : promis-srpper46-caps

code

system : http://loinc.org

code : 76712-9

display : I have trouble doing all of the activities with friends that I want to do [PROMIS]

text : I have trouble doing all of the activities with friends that I want to do.

extension

url : lang

value : de

extension

url : content

value : Es fällt mir schwer, allen Aktivitäten nachzugehen, die ich mit Freunden machen möchte.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale

item

linkId : PROMIS-16.PainInterference

text : Pain Interference

extension

url : lang

value : de

extension

url : content

value : Beeinträchtigung durch Schmerzen

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-painin9

code

system : http://loinc.org

code : 61758-9

display : How much did pain interfere with your day to day activities in past 7 days [PROMIS]

text : How much did pain interfere with your day-to-day activities?

extension

url : lang

value : de

extension

url : content

value : Wie sehr beeinträchtigen Schmerzen Ihre Alltagsaktivitäten?

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

item

linkId : promis-painin31

code

system : http://loinc.org

code : 61773-8

display : How much did pain interfere with your ability to participate in social activities in past 7 days [PROMIS]

text : How much did pain interfere with your ability to participate in social activities?

extension

url : lang

value : de

extension

url : content

value : Wie sehr beeinträchtigen Schmerzen Ihre Fähigkeit, an sozialen Aktivitäten teilzunehmen?

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

item

linkId : PROMIS-16.Cognition

text : Cognitive Function — Abilities

extension

url : lang

value : de

extension

url : content

value : Kognitive Funktionen — Fähigkeiten

url : http://hl7.org/fhir/StructureDefinition/translation

type : group

item

linkId : promis-pc27r

text : I have been able to remember to do things, like take medicine or buy something I needed.

extension

url : lang

value : de

extension

url : content

value : Ich bin fähig gewesen, mich an Dinge zu erinnern, die ich tun musste, wie z.B. Medikamente einnehmen oder etwas kaufen, das ich benötigte.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

item

linkId : promis-pc-caps3r

text : I have been able to think clearly without extra effort.

extension

url : lang

value : de

extension

url : content

value : Ich bin fähig gewesen, klar zu denken, ohne mich extra anzustrengen.

url : http://hl7.org/fhir/StructureDefinition/translation

type : choice

required : True

answerValueSet : https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale

{

"resourceType": "Questionnaire",

"id": "mii-qst-pro-promis-16",

"meta": {

"profile": [

"https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/StructureDefinition/mii-pr-pro-questionnaire|2027.0.0-ballot.1"

]

"language": "en",

"extension": [

{

"url": "http://hl7.org/fhir/StructureDefinition/artifact-versionAlgorithm",

"valueCoding": {

"system": "http://hl7.org/fhir/version-algorithm",
"code": "natural",
"display": "Natural"

}

{

"extension": [

{

"url": "displayable",

"valueBoolean": true

{

"url": "collectable",

"valueBoolean": true

{

"url": "calculatable",

"valueBoolean": false

{

"url": "extractable",

"valueBoolean": true

{

"url": "domainAligned",

"valueBoolean": true

}

"url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/StructureDefinition/mii-ex-pro-questionnaire-capabilities"

}

"url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/Questionnaire/mii-qst-pro-promis-16",

"version": "2027.0.0-ballot.1",

"title": "MII QST PRO PROMIS-16 (Adults)",

"status": "draft",

"experimental": true,

"publisher": "Medizininformatik-Initiative (MII) – PRO Modul",

"contact": [

{

"name": "PROMIS National Center Deutschland (CPCOR)",

"telecom": [

{

"system": "url",

"value": "https://cpcor.charite.de/promis_national_center_deutschland/nutzungsanfragen"

}

]

}

"description": "PROMIS-16 Profile v1.0 - Ultra-short 16-item HRQoL Profile across 8 domains (Edelen et al. 2024, doi:10.1007/s11136-023-03597-6). T-score calculation per Supplement S4 is delegated to a CQL Library (see roadmap 2027).",

"useContext": [

{

"code": {

"system": "http://terminology.hl7.org/CodeSystem/usage-context-type",

"code": "focus"

"valueReference": {

"display": "PROMIS (Patient-Reported Outcomes Measurement Information System) (https://www.healthmeasures.net/explore-measurement-systems/promis)"

}

{

"code": {

"system": "http://terminology.hl7.org/CodeSystem/usage-context-type",

"code": "focus"

"valueReference": {

"display": "PROMIS National Center Deutschland (CPCOR Charité) — Curator of the official German translations provided by PCOR-MII (https://cpcor.charite.de/promis_national_center_deutschland)"

}

{

"code": {

"system": "http://terminology.hl7.org/CodeSystem/usage-context-type",

"code": "focus"

"valueReference": {

"display": "PROMIS-16 Profile (Edelen et al. 2024, Qual Life Res) (https://doi.org/10.1007/s11136-023-03597-6)"

}

"copyright": "The FHIR Questionnaire resource (linkIds, extensions, score calculation logic, observation extraction definitions) is part of the MII PRO Module and is licensed under CC-BY 4.0.\n\nThe PROMIS items contained herein (item text, response options, scoring algorithms, IRT parameters) are © 2008–2024 PROMIS Health Organization and PROMIS Cooperative Group. PROMIS® is a registered trademark. See https://www.healthmeasures.net for the upstream license.\n\nThe official German translations are provided by PCOR-MII (Patient-Centered Outcomes Research within the Medizininformatik-Initiative) and curated by the PROMIS National Center Germany (CPCOR, Charité – Universitätsmedizin Berlin; head: Felix Fischer).\n\nInstitutional use outside the PCOR-MII / MII context requires a usage request to CPCOR: https://cpcor.charite.de/promis_national_center_deutschland/nutzungsanfragen\n\nLOINC® codes are © Regenstrief Institute, Inc. and used under the LOINC license: https://loinc.org/license/",

"code": [

{

"system": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/CodeSystem/mii-cs-pro-questionnaire-catalogue",
"code": "promis-promis16",
"display": "PROMIS-16 Profile Questionnaire (ultra-short 8-domain profile)"

}

"item": [

{

"linkId": "PROMIS-16.PhysicalFunction",

"text": "Physical Function",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Körperliche Funktion"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-pfa21",
"code": [
{
"system": "http://loinc.org",
"code": "62826-3",
"display": "Are you able to go up and down stairs at a normal pace [PROMIS]"
}
],
"text": "Are you able to go up and down stairs at a normal pace?",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Können Sie mit normaler Geschwindigkeit Treppen hoch- und runtergehen?"
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-physical-function-response-scale"

{

"linkId": "promis-pfa23",
"code": [
{
"system": "http://loinc.org",
"code": "62827-1",
"display": "Are you able to go for a walk of at least 15 minutes [PROMIS]"
}
],
"text": "Are you able to go for a walk of at least 15 minutes?",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Können Sie mindestens 15 Minuten lang spazieren gehen?"
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-physical-function-response-scale"

}

]

{

"linkId": "PROMIS-16.Anxiety",

"text": "Emotional Distress — Anxiety",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Emotionale Belastung — Angst"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-edanx40",
"code": [
{
"system": "http://loinc.org",
"code": "61941-1",
"display": "I found it hard to focus on anything other than my anxiety in past 7 days"
}
],
"text": "I found it hard to focus on anything other than my anxiety.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich fand es schwer, auf etwas anderes zu achten als auf meine Angst."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

{

"linkId": "promis-edanx41",
"code": [
{
"system": "http://loinc.org",
"code": "61942-9",
"display": "My worries overwhelmed me in past 7 days"
}
],
"text": "My worries overwhelmed me.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Meine Sorgen haben mich überwältigt."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

}

]

{

"linkId": "PROMIS-16.Depression",

"text": "Emotional Distress — Depression",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Emotionale Belastung — Depressivität"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-eddep29",
"code": [
{
"system": "http://loinc.org",
"code": "61967-6",
"display": "I felt depressed in past 7 days [PROMIS]"
}
],
"text": "I felt depressed.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich fühlte mich niedergeschlagen."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

{

"linkId": "promis-eddep41",
"code": [
{
"system": "http://loinc.org",
"code": "61973-4",
"display": "I felt hopeless in past 7 days [PROMIS]"
}
],
"text": "I felt hopeless.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich fühlte mich hoffnungslos."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

}

]

{

"linkId": "PROMIS-16.Fatigue",

"text": "Fatigue",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Erschöpfung"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-hi7",
"code": [
{
"system": "http://loinc.org",
"code": "61878-5",
"display": "I feel fatigued during the past 7 days [PROMIS]"
}
],
"text": "I feel fatigued.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich bin erschöpft."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

{

"linkId": "promis-an3",
"code": [
{
"system": "http://loinc.org",
"code": "61882-7",
"display": "I had trouble starting things because I was tired in past 7 days [PROMIS]"
}
],
"text": "I had trouble starting things because I was tired.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Es fällt mir schwer, etwas anzufangen, weil ich müde bin."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

}

]

{

"linkId": "PROMIS-16.Sleep",

"text": "Sleep-related Impairment / Sleep Disturbance",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Schlafbezogene Beeinträchtigungen / Schlafbeeinträchtigung"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-sleep25",
"text": "I had problems during the day because of poor sleep.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich hatte tagsüber Probleme, weil ich schlecht geschlafen habe."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

{

"linkId": "promis-sleep90",
"text": "I had trouble sleeping.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Es fiel mir schwer zu schlafen."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

}

]

{

"linkId": "PROMIS-16.SocialRoles",

"text": "Ability to Participate in Social Roles and Activities",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Teilhabe an sozialen Rollen und Aktivitäten"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-srpper31-caps",
"text": "I have trouble taking care of my regular personal responsibilities.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Es fällt mir schwer, mich um meine regelmäßigen persönlichen Verpflichtungen zu kümmern."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

{

"linkId": "promis-srpper46-caps",
"code": [
{
"system": "http://loinc.org",
"code": "76712-9",
"display": "I have trouble doing all of the activities with friends that I want to do [PROMIS]"
}
],
"text": "I have trouble doing all of the activities with friends that I want to do.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Es fällt mir schwer, allen Aktivitäten nachzugehen, die ich mit Freunden machen möchte."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale"

}

]

{

"linkId": "PROMIS-16.PainInterference",

"text": "Pain Interference",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Beeinträchtigung durch Schmerzen"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-painin9",
"code": [
{
"system": "http://loinc.org",
"code": "61758-9",
"display": "How much did pain interfere with your day to day activities in past 7 days [PROMIS]"
}
],
"text": "How much did pain interfere with your day-to-day activities?",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Wie sehr beeinträchtigen Schmerzen Ihre Alltagsaktivitäten?"
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

{

"linkId": "promis-painin31",
"code": [
{
"system": "http://loinc.org",
"code": "61773-8",
"display": "How much did pain interfere with your ability to participate in social activities in past 7 days [PROMIS]"
}
],
"text": "How much did pain interfere with your ability to participate in social activities?",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Wie sehr beeinträchtigen Schmerzen Ihre Fähigkeit, an sozialen Aktivitäten teilzunehmen?"
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

}

]

{

"linkId": "PROMIS-16.Cognition",

"text": "Cognitive Function — Abilities",

"_text": {

"extension": [

{

"extension": [

{

"url": "lang",

"valueCode": "de"

{

"url": "content",

"valueString": "Kognitive Funktionen — Fähigkeiten"

}

"url": "http://hl7.org/fhir/StructureDefinition/translation"

}

]

"type": "group",

"item": [

{

"linkId": "promis-pc27r",
"text": "I have been able to remember to do things, like take medicine or buy something I needed.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich bin fähig gewesen, mich an Dinge zu erinnern, die ich tun musste, wie z.B. Medikamente einnehmen oder etwas kaufen, das ich benötigte."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

{

"linkId": "promis-pc-caps3r",
"text": "I have been able to think clearly without extra effort.",
"_text": {
"extension": [
{
"extension": [
{
"url": "lang",
"valueCode": "de"
},
{
"url": "content",
"valueString": "Ich bin fähig gewesen, klar zu denken, ohne mich extra anzustrengen."
}
],
"url": "http://hl7.org/fhir/StructureDefinition/translation"
}
]
},
"type": "choice",
"required": true,
"answerValueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale"

}

]

}

]

}

<meta>

</meta>

<system value="http://hl7.org/fhir/version-algorithm" />
<code value="natural" />
<display value="Natural" />

</valueCoding>

</extension>

</extension>

</extension>

</extension>

</extension>

</extension>

</telecom>

</contact>

<code>

</code>

</valueReference>

</useContext>

<code>

</code>

</valueReference>

</useContext>

<code>

</code>

</valueReference>

</useContext>

<code>

<system value="https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/CodeSystem/mii-cs-pro-questionnaire-catalogue" />
<code value="promis-promis16" />
<display value="PROMIS-16 Profile Questionnaire (ultra-short 8-domain profile)" />

</code>

<item>

</extension>

</extension>

</text>

<item>

<code>

<system value="http://loinc.org" />
<code value="62826-3" />
<display value="Are you able to go up and down stairs at a normal pace [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

<code>

<system value="http://loinc.org" />
<code value="62827-1" />
<display value="Are you able to go for a walk of at least 15 minutes [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

</extension>

</extension>

</text>

<item>

<code>

<system value="http://loinc.org" />
<code value="61941-1" />
<display value="I found it hard to focus on anything other than my anxiety in past 7 days" />

</code>

</extension>

</extension>

</text>

</item>

<item>

<code>

<system value="http://loinc.org" />
<code value="61942-9" />
<display value="My worries overwhelmed me in past 7 days" />

</code>

</extension>

</extension>

</text>

</item>

<item>

</extension>

</extension>

</text>

<item>

<code>

<system value="http://loinc.org" />
<code value="61967-6" />
<display value="I felt depressed in past 7 days [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

<code>

<system value="http://loinc.org" />
<code value="61973-4" />
<display value="I felt hopeless in past 7 days [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

</extension>

</extension>

</text>

<item>

<code>

<system value="http://loinc.org" />
<code value="61878-5" />
<display value="I feel fatigued during the past 7 days [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

<code>

<system value="http://loinc.org" />
<code value="61882-7" />
<display value="I had trouble starting things because I was tired in past 7 days [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

</extension>

</extension>

</text>

<item>

<linkId value="promis-sleep25" />
<text value="I had problems during the day because of poor sleep.">
<extension url="http://hl7.org/fhir/StructureDefinition/translation">
<extension url="lang">
<valueCode value="de" />
</extension>
<extension url="content">
<valueString value="Ich hatte tagsüber Probleme, weil ich schlecht geschlafen habe." />
</extension>
</extension>
</text>
<type value="choice" />
<required value="true" />
<answerValueSet value="https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale" />

</item>

<item>

<linkId value="promis-sleep90" />
<text value="I had trouble sleeping.">
<extension url="http://hl7.org/fhir/StructureDefinition/translation">
<extension url="lang">
<valueCode value="de" />
</extension>
<extension url="content">
<valueString value="Es fiel mir schwer zu schlafen." />
</extension>
</extension>
</text>
<type value="choice" />
<required value="true" />
<answerValueSet value="https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale" />

</item>

<item>

</extension>

</extension>

</text>

<item>

<linkId value="promis-srpper31-caps" />
<text value="I have trouble taking care of my regular personal responsibilities.">
<extension url="http://hl7.org/fhir/StructureDefinition/translation">
<extension url="lang">
<valueCode value="de" />
</extension>
<extension url="content">
<valueString value="Es fällt mir schwer, mich um meine regelmäßigen persönlichen Verpflichtungen zu kümmern." />
</extension>
</extension>
</text>
<type value="choice" />
<required value="true" />
<answerValueSet value="https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-frequency-response-scale" />

</item>

<item>

<code>

<system value="http://loinc.org" />
<code value="76712-9" />
<display value="I have trouble doing all of the activities with friends that I want to do [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

</extension>

</extension>

</text>

<item>

<code>

<system value="http://loinc.org" />
<code value="61758-9" />
<display value="How much did pain interfere with your day to day activities in past 7 days [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

<code>

<system value="http://loinc.org" />
<code value="61773-8" />
<display value="How much did pain interfere with your ability to participate in social activities in past 7 days [PROMIS]" />

</code>

</extension>

</extension>

</text>

</item>

<item>

</extension>

</extension>

</text>

<item>

<linkId value="promis-pc27r" />
<text value="I have been able to remember to do things, like take medicine or buy something I needed.">
<extension url="http://hl7.org/fhir/StructureDefinition/translation">
<extension url="lang">
<valueCode value="de" />
</extension>
<extension url="content">
<valueString value="Ich bin fähig gewesen, mich an Dinge zu erinnern, die ich tun musste, wie z.B. Medikamente einnehmen oder etwas kaufen, das ich benötigte." />
</extension>
</extension>
</text>
<type value="choice" />
<required value="true" />
<answerValueSet value="https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale" />

</item>

<item>

<linkId value="promis-pc-caps3r" />
<text value="I have been able to think clearly without extra effort.">
<extension url="http://hl7.org/fhir/StructureDefinition/translation">
<extension url="lang">
<valueCode value="de" />
</extension>
<extension url="content">
<valueString value="Ich bin fähig gewesen, klar zu denken, ohne mich extra anzustrengen." />
</extension>
</extension>
</text>
<type value="choice" />
<required value="true" />
<answerValueSet value="https://www.medizininformatik-initiative.de/fhir/ext/modul-pro/ValueSet/mii-vs-pro-promis-intensity-response-scale" />

</item>

</Questionnaire>

Abgedeckte Domänen

Domäne	Items	PCOR-MII Variable IDs
Physical Function	2	PFA21, PFA23
Anxiety	2	EDANX40, EDANX41
Depression	2	EDDEP29, EDDEP41
Fatigue	2	HI7, AN3
Sleep Disturbance	2	Sleep25, Sleep90
Social Roles & Activities	2	SRPPER31_CaPS, SRPPER46_CaPS
Pain Interference	2	PAININ9, PAININ31
Cognitive Function	2	PC27r, PC-CaPS3r

Capabilities

Displayable -- ja
Collectable -- ja
Calculatable -- nein (bewusste Entscheidung; siehe Score-Berechnung unten)
Extractable -- ja
Domain-aligned -- ja

Score-Berechnung (in dieser Version nicht implementiert)

PROMIS-16 ist auf die Berechnung des PROMIS-Präferenz-Scores (PROPr) ausgelegt — eines Utility-Scores analog zum EQ-5D-Index, der für vergleichende Wirksamkeits- und Kosten-Nutzen-Analysen verwendet wird. Die vollständige Score-Berechnung erfolgt in 3 Stufen:

8 Domänen-T-Scores -- pro Domäne aus einem 5×5-Antwortmusterraster (Pattern-Lookup nach Edelen et al. 2024 Supplement S4)
PROMIS-Theta-Werte -- IRT-basierte latente Konstrukte je Domäne
PROPr Summary Score -- utility-basiert aus den 8 Thetas (Dewitt et al. 2018)

In der aktuellen Version (2026.5.0) ist die Score-Berechnung bewusst nicht implementiert. Das Questionnaire trägt calculatable = false und dient zunächst der reinen Datenerfassung. Die Score-Berechnung soll später über eine CQL Library mii-lib-promis-16 und/oder Anbindung an die offizielle PROMIS Assessment Center API ergänzt werden.

Hinweis zum Anwendungszweck (laut PHO): Der PROPr-Score ist für Berichterstattung auf Gruppenebene vorgesehen. Für die präzise individuelle klinische Bewertung sind Domain-Scores allein nicht zuverlässig — sie können aber als Screening dienen.

Referenz Score-Methodik: Dewitt B, Feeny D, Fischhoff B, et al. Estimation of a Preference-Based Summary Score for PROMIS: The PROMIS®-Preference (PROPr) Scoring System. Med Decis Making. 2018;38(6):683-698. doi:10.1177/0272989X18776637

Item-Überlapp mit PROMIS-29 / Cog Fn SF 4a

11 der 16 PROMIS-16-Items finden sich auch im PROMIS-29-Korpus, 5 sind PROMIS-16-spezifisch:

PROMIS-16 Item	Auch in PROMIS-29?	Auch in Cog Fn SF 4a?
PFA21, PFA23	✓	--
EDANX40, EDANX41	✓	--
EDDEP29, EDDEP41	✓	--
HI7, AN3	✓	--
Sleep25	--	--
Sleep90	--	--
SRPPER31_CaPS	--	--
SRPPER46_CaPS	✓	--
PAININ9, PAININ31	✓	--
PC27r	--	--
PC-CaPS3r	--	--

Praktische Konsequenz: Wer PROMIS-29 + Cog Fn SF 4a erhebt, kann kein vollständiges PROMIS-16 extrahieren — es fehlen die 5 fett markierten Items.

Vergleich PROMIS-16 vs. PROMIS-29

Aspekt	PROMIS-16	PROMIS-29
Items gesamt	16	29 (28 Likert + 1 NRS)
Items je Domäne	2	4
Abgedeckte Domänen	8 (inkl. Cognitive Function)	7 + 1 NRS (ohne Cognitive Function)
Score-Methode	Pattern-Lookup + PROPr Utility (CQL geplant)	Summenscore + T-Score-Lookup
Ausfüllzeit	~3-5 min	~7-10 min
Einsatzkontext	Wiederholte Messung, Screening, PROPr-Studien	Detaillierte Baseline-Erfassung

Sprachunterstützung

Primärsprache: Englisch (validierte PHO-Version)
Deutsche Übersetzung: Via translation-Extension; Wordings aus dem offiziellen PROMIS Health Organization PDF (PROMIS-16 Profile v2.1 PROPr, German, 20 September 2024) und cross-confirmed mit dem PCOR-MII Master Item-Level Dictionary.

Lizenzierung & Urheberrecht

PROMIS-Items sind urheberrechtlich geschützt. Die offiziellen deutschen Übersetzungen werden durch PCOR-MII bereitgestellt und durch das PROMIS National Center Deutschland (CPCOR Charité, Leitung: Felix Fischer) kuratiert.

Für die institutionelle Implementierung außerhalb des PCOR-MII-Kontexts ist eine Nutzungsanfrage bei CPCOR erforderlich: https://cpcor.charite.de/promis_national_center_deutschland/nutzungsanfragen

Details zur Schichten-Attribution (MII FHIR-Struktur + PROMIS Items + deutsche Übersetzung + LOINC) siehe Index-Seite PROMIS.

Referenzen

Edelen MO, Rodriguez A, Herman P, Hays RD. PROMIS®-16: development and preliminary psychometric evaluation of the next generation PROMIS® short form set. Qual Life Res. 2024. doi:10.1007/s11136-023-03597-6
Dewitt B, Feeny D, Fischhoff B, et al. Estimation of a Preference-Based Summary Score for PROMIS: The PROMIS®-Preference (PROPr) Scoring System. Med Decis Making. 2018;38(6):683-698. doi:10.1177/0272989X18776637
PROMIS Official Site
PROMIS National Center Deutschland (CPCOR)