ServiceRequest

ServiceRequest-NonWGSTestOrder-VariantReinterpretation-Example

Example of a ServiceRequest, submitted to request variant reinterpretation. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrder-VariantReinterpretation-Example",
    "basedOn":  [
        {
            "reference": "ServiceReques/ServiceRequest-NonWGSTestOrderForm-SyndromicEpilepsy-Example"
        }
    ],
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R442",
                "display": "Variant Re-interpretation"
            }
        ]
    },
    "orderDetail":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                    "code": "R59",
                    "display": "Early onset or syndromic epilepsy"
                }
            ]
        }
    ],
    "subject": {
        "reference": "Patient/Patient-SalimaPomfrets-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303444"
        }
    },
    "authoredOn": "2023-10-01T10:08:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                    "code": "261004008",
                    "display": "Diagnostic"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        }
    ],
    "note":  [
        {
            "text": "No sample required."
        },
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ For example: new evidence available that will likely change the classification of the variant- identification of additional patient(s) with the same genetic variant"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrder-VariantReinterpretation-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <basedOn>
        <reference value="ServiceReques/ServiceRequest-NonWGSTestOrderForm-SyndromicEpilepsy-Example" />
    </basedOn>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R442" />
            <display value="Variant Re-interpretation" />
        </coding>
    </code>
    <orderDetail>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R59" />
            <display value="Early onset or syndromic epilepsy" />
        </coding>
    </orderDetail>
    <subject>
        <reference value="Patient/Patient-SalimaPomfrets-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303444" />
        </identifier>
    </subject>
    <authoredOn value="2023-10-01T10:08:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmith-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="261004008" />
            <display value="Diagnostic" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <note>
        <text value="No sample required." />
    </note>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ For example: new evidence available that will likely change the classification of the variant- identification of additional patient(s) with the same genetic variant" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-Cancellation-Example

Example of a ServiceRequest, submitted to request a test cancellation. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-Cancellation-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R67.1",
                "display": "Monogenic hearing loss"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-MeirLieberman-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-08-05T10:08:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmithENT-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        },
        {
            "reference": "Observation/Observation-NatureAndAgeOfHearingLoss-Example"
        }
    ],
    "specimen":  [
        {
            "display": "Specimen/Specimen-BloodEDTA-Example"
        }
    ],
    "note":  [
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms Patient in need of test...example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-Cancellation-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R67.1" />
            <display value="Monogenic hearing loss" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-MeirLieberman-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-05T10:08:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmithENT-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NatureAndAgeOfHearingLoss-Example" />
    </supportingInfo>
    <specimen>
        <display value="Specimen/Specimen-BloodEDTA-Example" />
    </specimen>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms Patient in need of test...example" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-CancerSolidTumor-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-CancerSolidTumor-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        },
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-AdditionalContact",
            "valueReference": {
                "reference": "PractitionerRole/PractitionerRole-AnnaLaneKingstonPathology-Example"
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "cancer-non-wgs",
                    "display": "Cancer - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "M119.5",
                "display": "Multi Target NGS Panel Small"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-PatrickSammy-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307555"
        }
    },
    "authoredOn": "2023-09-08",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithKingstonPathology-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "335741000000100",
                    "display": "Recurrence of tumour"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RJZ"
            },
            "display": "KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST"
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-Cellularity-Example"
        },
        {
            "reference": "Observation/Observation-TumorType-Example"
        },
        {
            "reference": "Observation/Observation-Necrosis-Example"
        },
        {
            "reference": "Observation/Observation-NeoplasticCell-Example"
        },
        {
            "reference": "Condition/Condition-LungTumor-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-SolidTumor-Example"
        }
    ],
    "note":  [
        {
            "text": "Free text for diagnosis/reason for referral, transplant, life status at time of request details/ e.g. malignant tumour - molecular assessment will aid management"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-CancerSolidTumor-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-AdditionalContact">
        <valueReference>
            <reference value="PractitionerRole/PractitionerRole-AnnaLaneKingstonPathology-Example" />
        </valueReference>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="cancer-non-wgs" />
            <display value="Cancer - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="M119.5" />
            <display value="Multi Target NGS Panel Small" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-PatrickSammy-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307555" />
        </identifier>
    </subject>
    <authoredOn value="2023-09-08" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithKingstonPathology-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RJZ" />
        </identifier>
        <display value="KING&#39;S COLLEGE HOSPITAL NHS FOUNDATION TRUST" />
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="335741000000100" />
            <display value="Recurrence of tumour" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-Cellularity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-TumorType-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Necrosis-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NeoplasticCell-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-LungTumor-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-SolidTumor-Example" />
    </specimen>
    <note>
        <text value="Free text for diagnosis/reason for referral, transplant, life status at time of request details/ e.g. malignant tumour - molecular assessment will aid management" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-CascadeTesting-Example

Example of a ServiceRequest, submitted to request a cascade test. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-CascadeTesting-Example",
    "basedOn":  [
        {
            "reference": "ServiceRequest-NonWGSTestOrderForm-FatherOfFayMutlow-Example"
        }
    ],
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R134",
                "display": "Familial Hypercholesterolaemia"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-FayMutlow-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307806"
        }
    },
    "authoredOn": "2023-10-04T11:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-MarySmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "473145005",
                    "display": "Possible familial hypercholesterolemia"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-DutchLipidScore-Example"
        },
        {
            "reference": "Observation/Observation-QueryXanthoma-Example"
        },
        {
            "reference": "Observation/Observation-SimonBroomeCriteria-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-BloodEDTA-WithCollectoinDetails-Example"
        }
    ],
    "note":  [
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms"
        },
        {
            "text": "Father tested positive for FH. Confirmation required if daughter is positive for FH"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-CascadeTesting-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <basedOn>
        <reference value="ServiceRequest-NonWGSTestOrderForm-FatherOfFayMutlow-Example" />
    </basedOn>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R134" />
            <display value="Familial Hypercholesterolaemia" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-FayMutlow-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307806" />
        </identifier>
    </subject>
    <authoredOn value="2023-10-04T11:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-MarySmith-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="473145005" />
            <display value="Possible familial hypercholesterolemia" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DutchLipidScore-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-QueryXanthoma-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-SimonBroomeCriteria-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-BloodEDTA-WithCollectoinDetails-Example" />
    </specimen>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms" />
    </note>
    <note>
        <text value="Father tested positive for FH. Confirmation required if daughter is positive for FH" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-DeceasedPatient-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-DeceasedPatient-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R138",
                "display": "Sudden Cardiac Death"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-AnitaLambertsDeceasedPatient-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303649"
        }
    },
    "authoredOn": "2023-11-01T10:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        }
    ],
    "specimen":  [
        {
            "display": "Blood EDTA Specimen to be provided later"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms."
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-DeceasedPatient-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R138" />
            <display value="Sudden Cardiac Death" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-AnitaLambertsDeceasedPatient-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303649" />
        </identifier>
    </subject>
    <authoredOn value="2023-11-01T10:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmith-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <specimen>
        <display value="Blood EDTA Specimen to be provided later" />
    </specimen>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms." />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-Example

Example of a ServiceRequest. The scenario this is for is detailed on Non-WGS Test Request - Rare Disease

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R67.2",
                "display": "Monogenic hearing loss"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-MeirLieberman-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-08-05",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmithENT-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Condition/Condition-HearingLoss-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/Patient in need of test...example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R67.2" />
            <display value="Monogenic hearing loss" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-MeirLieberman-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-05" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmithENT-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-HearingLoss-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/Patient in need of test...example" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-FetalScenario-Example

Example of a ServiceRequest for a foetus. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-FetalScenario-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "urgent",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R21",
                "display": "Fetal anomalies with a likely genetic cause"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-FoetusOfRyanneBoulder-Example",
        "identifier":  [
            {
                "system": "urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24",
                "value": "FT-RWT13521",
                "assigner": {
                    "identifier": {
                        "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                        "value": "RAX"
                    }
                }
            }
        ]
    },
    "authoredOn": "2023-09-25",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-LoisLaneKingstonClinicalGenetics-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "243787009",
                    "display": "Antenatal screening"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-HistoryOfFetalLoss-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnionRyanneBoulder-Example"
        },
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-PregnancyConfirmation-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoFirstTrimesterFetalAnomalies-Example"
        },
        {
            "reference": "Observation/Observation-NoSecondTrimesterFetalAnomalies-Example"
        },
        {
            "reference": "Procedure/Procedure-InVitroFertilisation-Example"
        }
    ],
    "note":  [
        {
            "text": "Samples are to be provided at a later date"
        },
        {
            "text": "No family history of relevant testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-FetalScenario-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="urgent" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R21" />
            <display value="Fetal anomalies with a likely genetic cause" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-FoetusOfRyanneBoulder-Example" />
        <identifier>
            <system value="urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24" />
            <value value="FT-RWT13521" />
            <assigner>
                <identifier>
                    <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
                    <value value="RAX" />
                </identifier>
            </assigner>
        </identifier>
    </subject>
    <authoredOn value="2023-09-25" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-LoisLaneKingstonClinicalGenetics-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="243787009" />
            <display value="Antenatal screening" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-HistoryOfFetalLoss-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnionRyanneBoulder-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-PregnancyConfirmation-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoFirstTrimesterFetalAnomalies-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoSecondTrimesterFetalAnomalies-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Procedure/Procedure-InVitroFertilisation-Example" />
    </supportingInfo>
    <note>
        <text value="Samples are to be provided at a later date" />
    </note>
    <note>
        <text value="No family history of relevant testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-FollowupTest-Example

Example of a ServiceRequest, submitted to request a follow-up test. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-FollowupTest-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R187",
                "display": "Cystic Fibrosis"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-AnitaLamberts-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303649"
        }
    },
    "authoredOn": "2023-11-01T10:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RJ1"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        }
    ],
    "note":  [
        {
            "text": "Specimen to be provided later"
        },
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms / For example: Adult with CT-proven bronchiectasis, chronic suppurative chest infection with colonisation by Pseudomonas and Staph aureus"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-FollowupTest-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R187" />
            <display value="Cystic Fibrosis" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-AnitaLamberts-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303649" />
        </identifier>
    </subject>
    <authoredOn value="2023-11-01T10:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmith-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RJ1" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <note>
        <text value="Specimen to be provided later" />
    </note>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms / For example: Adult with CT-proven bronchiectasis, chronic suppurative chest infection with colonisation by Pseudomonas and Staph aureus" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-HaemOncology-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-HaemOncology-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "cancer-non-wgs",
                    "display": "Cancer - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "M91",
                "display": "Acute Lymphoblastic Leukaemia"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-PatrickSammy-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-09-03T10:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithPathology-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "441308009",
                    "display": "New diagnosis"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-BlastPercentage-Example"
        },
        {
            "reference": "Observation/Observation-Bruising-Example"
        },
        {
            "reference": "Observation/Observation-Haemoglobin-Example"
        },
        {
            "reference": "Observation/Observation-Neutrophils-Example"
        },
        {
            "reference": "Observation/Observation-NucleatedCellCount-Example"
        },
        {
            "reference": "Observation/Observation-Platelets-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        },
        {
            "reference": "Observation/Observation-WhiteBloodCell-Example"
        },
        {
            "reference": "Condition/Condition-Hepatosplenomegaly-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-BoneMarrowAspiration-Example"
        }
    ],
    "note":  [
        {
            "text": "No Previous Relevant Test Report"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-HaemOncology-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="cancer-non-wgs" />
            <display value="Cancer - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="M91" />
            <display value="Acute Lymphoblastic Leukaemia" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-PatrickSammy-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-09-03T10:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithPathology-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="441308009" />
            <display value="New diagnosis" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-BlastPercentage-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Bruising-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Haemoglobin-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Neutrophils-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NucleatedCellCount-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Platelets-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-WhiteBloodCell-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-Hepatosplenomegaly-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-BoneMarrowAspiration-Example" />
    </specimen>
    <note>
        <text value="No Previous Relevant Test Report" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-HaemOncologyUpdated-Example

Example of an updated ServiceRequest (with additional version number and provenance history).

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-HaemOncologyUpdated-Example",
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-09-04T15:43:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "cancer-non-wgs",
                    "display": "Cancer - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "M91.4",
                "display": "Acute Lymphoblastic Leukaemia (FISH)"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-PatrickSammy-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-09-03T10:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithPathology-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "441308009",
                    "display": "New diagnosis"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RR8"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-BlastPercentage-Example"
        },
        {
            "reference": "Observation/Observation-Bruising-Example"
        },
        {
            "reference": "Observation/Observation-Haemoglobin-Example"
        },
        {
            "reference": "Observation/Observation-Neutrophils-Example"
        },
        {
            "reference": "Observation/Observation-NucleatedCellCount-Example"
        },
        {
            "reference": "Observation/Observation-Platelets-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        },
        {
            "reference": "Observation/Observation-WhiteBloodCell-Example"
        },
        {
            "reference": "Condition/Condition-Hepatosplenomegaly-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-BoneMarrowAspiration-Example"
        }
    ],
    "note":  [
        {
            "text": "M code modified to M91.4. Appropriate testing"
        },
        {
            "text": "No Previous Relevant Test Report"
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-ServiceRequest-NonWGSTestOrderForm-HaemOncology-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-HaemOncologyUpdated-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-09-04T15:43:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="cancer-non-wgs" />
            <display value="Cancer - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="M91.4" />
            <display value="Acute Lymphoblastic Leukaemia (FISH)" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-PatrickSammy-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-09-03T10:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithPathology-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RR8" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="441308009" />
            <display value="New diagnosis" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-BlastPercentage-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Bruising-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Haemoglobin-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Neutrophils-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NucleatedCellCount-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Platelets-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-WhiteBloodCell-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-Hepatosplenomegaly-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-BoneMarrowAspiration-Example" />
    </specimen>
    <note>
        <text value="M code modified to M91.4. Appropriate testing" />
    </note>
    <note>
        <text value="No Previous Relevant Test Report" />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-ServiceRequest-NonWGSTestOrderForm-HaemOncology-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-NewFollowupTest-Example

Example of a ServiceRequest requested as a follow-up to an existing test. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-NewFollowupTest-Example",
    "basedOn":  [
        {
            "reference": "ServiceRequest/ServiceRequest-NonWGSTestOrderForm-FollowupTest-Example"
        }
    ],
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R65.1",
                "display": "Aminoglycoside exposure posing risk to hearing"
            }
        ],
        "text": "Follow Up Test requested to aid interpretation. M code modified to: R65.1"
    },
    "subject": {
        "reference": "Patient/Patient-AnitaLamberts-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303649"
        }
    },
    "authoredOn": "2023-11-10T10:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-AndrewSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RJ1"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-BloodEDTA-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms /  For example: Adult with CT-proven bronchiectasis, chronic suppurative chest infection with colonisation by Pseudomonas and Staph aureus. Intital test ordered for Cystic Fibrosis."
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-NewFollowupTest-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <basedOn>
        <reference value="ServiceRequest/ServiceRequest-NonWGSTestOrderForm-FollowupTest-Example" />
    </basedOn>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R65.1" />
            <display value="Aminoglycoside exposure posing risk to hearing" />
        </coding>
        <text value="Follow Up Test requested to aid interpretation. M code modified to: R65.1" />
    </code>
    <subject>
        <reference value="Patient/Patient-AnitaLamberts-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303649" />
        </identifier>
    </subject>
    <authoredOn value="2023-11-10T10:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-AndrewSmith-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RJ1" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-BloodEDTA-Example" />
    </specimen>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms /  For example: Adult with CT-proven bronchiectasis, chronic suppurative chest infection with colonisation by Pseudomonas and Staph aureus. Intital test ordered for Cystic Fibrosis." />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-OutOfCountry-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-OutOfCountry-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        },
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-AdditionalContact",
            "valueReference": {
                "reference": "PractitionerRole/PractitionerRole-AnnaLane-Example"
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "cancer-non-wgs",
                    "display": "Cancer - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "M3.2",
                "display": "Breast Cancer (Oncotype DX)"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-KayBurbridge-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303541"
        }
    },
    "authoredOn": "2023-11-01T11:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithOncology-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RLU"
            },
            "display": "BIRMINGHAM WOMEN'S NHS FOUNDATION TRUST"
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-CellularityKayBurbridge-Example"
        },
        {
            "reference": "Observation/Observation-TumorTypeKayKayBurbridge-Example"
        },
        {
            "reference": "Observation/Observation-NecrosisKayBurbridge-Example"
        },
        {
            "reference": "Observation/Observation-NeoplasticCellKayBurbridge-Example"
        },
        {
            "reference": "Condition/Condition-BreastCancer-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-TissueResection-Example"
        }
    ],
    "note":  [
        {
            "text": "Free text for diagnosis/reason for referral, transplant, life status at time of request details/ e.g. e.g. ER positive, HER2 negative. lymph node negative, early breast cancer. Use exisiting tissue sample sent to lab"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-OutOfCountry-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-AdditionalContact">
        <valueReference>
            <reference value="PractitionerRole/PractitionerRole-AnnaLane-Example" />
        </valueReference>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="cancer-non-wgs" />
            <display value="Cancer - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="M3.2" />
            <display value="Breast Cancer (Oncotype DX)" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-KayBurbridge-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303541" />
        </identifier>
    </subject>
    <authoredOn value="2023-11-01T11:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithOncology-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RLU" />
        </identifier>
        <display value="BIRMINGHAM WOMEN&#39;S NHS FOUNDATION TRUST" />
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-CellularityKayBurbridge-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-TumorTypeKayKayBurbridge-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NecrosisKayBurbridge-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NeoplasticCellKayBurbridge-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-BreastCancer-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-TissueResection-Example" />
    </specimen>
    <note>
        <text value="Free text for diagnosis/reason for referral, transplant, life status at time of request details/ e.g. e.g. ER positive, HER2 negative. lymph node negative, early breast cancer. Use exisiting tissue sample sent to lab" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example

Example of a ServiceRequest using an existing specimen. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R134",
                "display": "Familial Hypercholesterolaemia"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-TimMclullichs-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303452"
        }
    },
    "authoredOn": "2023-11-02T11:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-OscarShields-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "1186936003",
                    "display": "Storage of specimen"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-DutchLipidScore-Example"
        },
        {
            "reference": "Observation/Observation-QueryXanthoma-Example"
        },
        {
            "reference": "Observation/Observation-SimonBroomeCriteria-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-BloodEDTA-WithCollectoinDetails-Example",
            "identifier":  [
                {
                    "system": "https://fhir.bwc.nhs.uk//Id/specimenId",
                    "value": "RQ3-RTH-698C0-17543",
                    "assigner": {
                        "identifier": {
                            "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                            "value": "RQ3"
                        }
                    }
                }
            ]
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ patient to be tested for FH, use existing DNA sample in storage"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R134" />
            <display value="Familial Hypercholesterolaemia" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-TimMclullichs-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303452" />
        </identifier>
    </subject>
    <authoredOn value="2023-11-02T11:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-OscarShields-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="1186936003" />
            <display value="Storage of specimen" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DutchLipidScore-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-QueryXanthoma-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-SimonBroomeCriteria-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-BloodEDTA-WithCollectoinDetails-Example" />
        <identifier>
            <system value="https://fhir.bwc.nhs.uk//Id/specimenId" />
            <value value="RQ3-RTH-698C0-17543" />
            <assigner>
                <identifier>
                    <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
                    <value value="RQ3" />
                </identifier>
            </assigner>
        </identifier>
    </specimen>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ patient to be tested for FH, use existing DNA sample in storage" />
    </note>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderFormUpdated-Cancellation-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderFormUpdated-Cancellation-Example",
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-08-08T15:43:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "revoked",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R67.1",
                "display": "Monogenic hearing loss"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-MeirLieberman-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-08-08T15:43:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmithENT-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-RiskOfInfection-Example"
        },
        {
            "reference": "Observation/Observation-NatureAndAgeOfHearingLoss-Example"
        }
    ],
    "specimen":  [
        {
            "display": "Specimen/Specimen-BloodEDTA-Example"
        }
    ],
    "note":  [
        {
            "text": "Test no longer required."
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms Patient in need of test...example"
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-ServiceRequest-NonWGSTestOrderFormCancellation-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderFormUpdated-Cancellation-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-08-08T15:43:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="revoked" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R67.1" />
            <display value="Monogenic hearing loss" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-MeirLieberman-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-08T15:43:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmithENT-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RiskOfInfection-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NatureAndAgeOfHearingLoss-Example" />
    </supportingInfo>
    <specimen>
        <display value="Specimen/Specimen-BloodEDTA-Example" />
    </specimen>
    <note>
        <text value="Test no longer required." />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms Patient in need of test...example" />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-ServiceRequest-NonWGSTestOrderFormCancellation-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderFormUpdated-FetalScenario-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderFormUpdated-FetalScenario-Example",
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-09-26T10:00:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "urgent",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R21",
                "display": "Fetal anomalies with a likely genetic cause"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-FoetusOfRyanneBoulder-Example",
        "identifier":  [
            {
                "system": "urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24",
                "value": "FT-RWT13521",
                "assigner": {
                    "identifier": {
                        "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                        "value": "RAX"
                    }
                }
            }
        ]
    },
    "authoredOn": "2023-09-26T10:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-LoisLaneKingstonClinicalGenetics-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "243787009",
                    "display": "Antenatal screening"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-HistoryOfFetalLoss-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnionRyanneBoulder-Example"
        },
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-PregnancyConfirmation-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoFirstTrimesterFetalAnomalies-Example"
        },
        {
            "reference": "Observation/Observation-NoSecondTrimesterFetalAnomalies-Example"
        },
        {
            "reference": "Procedure/Procedure-InVitroFertilisation-Example"
        },
        {
            "reference": "Specimen/Specimen-BloodEDTA-Example"
        },
        {
            "reference": "Specimen/Specimen-RyanneBoulderSaliva-Example"
        },
        {
            "reference": "Specimen/Specimen-RyanneBoulderPartnerSaliva-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of relevant testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder"
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-NonWGSTestOrderForm-FetalScenario-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderFormUpdated-FetalScenario-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-09-26T10:00:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="urgent" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R21" />
            <display value="Fetal anomalies with a likely genetic cause" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-FoetusOfRyanneBoulder-Example" />
        <identifier>
            <system value="urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24" />
            <value value="FT-RWT13521" />
            <assigner>
                <identifier>
                    <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
                    <value value="RAX" />
                </identifier>
            </assigner>
        </identifier>
    </subject>
    <authoredOn value="2023-09-26T10:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-LoisLaneKingstonClinicalGenetics-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="243787009" />
            <display value="Antenatal screening" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-HistoryOfFetalLoss-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnionRyanneBoulder-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-PregnancyConfirmation-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoFirstTrimesterFetalAnomalies-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoSecondTrimesterFetalAnomalies-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Procedure/Procedure-InVitroFertilisation-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-BloodEDTA-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-RyanneBoulderSaliva-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-RyanneBoulderPartnerSaliva-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of relevant testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder" />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-NonWGSTestOrderForm-FetalScenario-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-NonWGSTestOrderFormUpdated-SolidTumor-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-NonWGSTestOrderFormUpdated-SolidTumor-Example",
    "meta": {
        "versionId": "3",
        "lastUpdated": "2023-08-08T15:43:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        },
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-AdditionalContact",
            "valueReference": {
                "reference": "PractitionerRole/PractitionerRole-AnnaLaneKingstonPathology-Example"
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "cancer-non-wgs",
                    "display": "Cancer - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "M119.5",
                "display": "Multi Target NGS Panel Small"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-PatrickSammy-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307555"
        }
    },
    "authoredOn": "2023-09-08",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithKingstonPathology-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "335741000000100",
                    "display": "Recurrence of tumour"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RJZ"
            },
            "display": "KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST"
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-Cellularity-Example"
        },
        {
            "reference": "Observation/Observation-TumorType-Example"
        },
        {
            "reference": "Observation/Observation-Necrosis-Example"
        },
        {
            "reference": "Observation/Observation-NeoplasticCell-Example"
        },
        {
            "reference": "Condition/Condition-LungTumor-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-SolidTumor-Example"
        }
    ],
    "note":  [
        {
            "text": "Additional portion of Sample X was provided."
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-NonWGSTestOrderFormUpdated-SolidTumor-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-NonWGSTestOrderFormUpdated-SolidTumor-Example" />
    <meta>
        <versionId value="3" />
        <lastUpdated value="2023-08-08T15:43:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-AdditionalContact">
        <valueReference>
            <reference value="PractitionerRole/PractitionerRole-AnnaLaneKingstonPathology-Example" />
        </valueReference>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="cancer-non-wgs" />
            <display value="Cancer - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="M119.5" />
            <display value="Multi Target NGS Panel Small" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-PatrickSammy-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307555" />
        </identifier>
    </subject>
    <authoredOn value="2023-09-08" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithKingstonPathology-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RJZ" />
        </identifier>
        <display value="KING&#39;S COLLEGE HOSPITAL NHS FOUNDATION TRUST" />
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="335741000000100" />
            <display value="Recurrence of tumour" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-Cellularity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-TumorType-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Necrosis-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NeoplasticCell-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-LungTumor-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-SolidTumor-Example" />
    </specimen>
    <note>
        <text value="Additional portion of Sample X was provided." />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-NonWGSTestOrderFormUpdated-SolidTumor-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-SavedTestOrder-Example

Example of a ServiceRequest retrieved from the central broker. After being saved on the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-SavedTestOrder-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "identifier":  [
        {
            "system": "https://fhir.nhs.uk/Id/GMSOrder",
            "value": "ROA43728"
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R67.2",
                "display": "Monogenic hearing loss"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-MeirLieberman-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-08-05",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmithENT-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Condition/Condition-HearingLoss-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient in need of test...example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-SavedTestOrder-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <identifier>
        <system value="https://fhir.nhs.uk/Id/GMSOrder" />
        <value value="ROA43728" />
    </identifier>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R67.2" />
            <display value="Monogenic hearing loss" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-MeirLieberman-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-05" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmithENT-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-HearingLoss-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient in need of test...example" />
    </note>
</ServiceRequest>

ServiceRequest-SavedTestOrderUpdated-CascadeTesting-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-SavedTestOrderUpdated-CascadeTesting-Example",
    "basedOn":  [
        {
            "reference": "ServiceRequest-NonWGSTestOrderForm-FatherOfFayMutlow-Example"
        }
    ],
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-10-06T09:00:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R134",
                "display": "Familial Hypercholesterolaemia"
            }
        ]
    },
    "orderDetail":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                    "code": "R242.1",
                    "display": "Predictive testing for known familial mutation(s)"
                }
            ]
        }
    ],
    "subject": {
        "reference": "Patient/Patient-FayMutlow-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307806"
        }
    },
    "authoredOn": "2023-10-04T11:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-MarySmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "473145005",
                    "display": "Possible familial hypercholesterolemia"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-DutchLipidScore-Example"
        },
        {
            "reference": "Observation/Observation-QueryXanthoma-Example"
        },
        {
            "reference": "Observation/Observation-SimonBroomeCriteria-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-FayMutlowBloodEDTA-Example"
        }
    ],
    "note":  [
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms"
        },
        {
            "text": "Father tested positive for FH. Confirmation required if daughter is postive for FH"
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-ServiceRequestUpdate-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-SavedTestOrderUpdated-CascadeTesting-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-10-06T09:00:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <basedOn>
        <reference value="ServiceRequest-NonWGSTestOrderForm-FatherOfFayMutlow-Example" />
    </basedOn>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R134" />
            <display value="Familial Hypercholesterolaemia" />
        </coding>
    </code>
    <orderDetail>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R242.1" />
            <display value="Predictive testing for known familial mutation(s)" />
        </coding>
    </orderDetail>
    <subject>
        <reference value="Patient/Patient-FayMutlow-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307806" />
        </identifier>
    </subject>
    <authoredOn value="2023-10-04T11:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-MarySmith-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="473145005" />
            <display value="Possible familial hypercholesterolemia" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DutchLipidScore-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-QueryXanthoma-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-SimonBroomeCriteria-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-FayMutlowBloodEDTA-Example" />
    </specimen>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms" />
    </note>
    <note>
        <text value="Father tested positive for FH. Confirmation required if daughter is postive for FH" />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-ServiceRequestUpdate-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-SavedTestOrderUpdated-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-SavedTestOrderUpdated-Example",
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-08-10T11:10:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "identifier":  [
        {
            "system": "https://fhir.nhs.uk/Id/GMSOrder",
            "value": "ROA43728"
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-non-wgs",
                    "display": "Rare Disease - Non-WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R67.1",
                "display": "Monogenic hearing loss"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-MeirLieberman-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307873"
        }
    },
    "authoredOn": "2023-08-05",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-GeneSmithENT-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/sds-user-id",
            "value": "9999999999"
        }
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Condition/Condition-HearingLoss-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient in need of test...example"
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-ServiceRequestUpdate-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-SavedTestOrderUpdated-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-08-10T11:10:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <identifier>
        <system value="https://fhir.nhs.uk/Id/GMSOrder" />
        <value value="ROA43728" />
    </identifier>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-non-wgs" />
            <display value="Rare Disease - Non-WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R67.1" />
            <display value="Monogenic hearing loss" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-MeirLieberman-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307873" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-05" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-GeneSmithENT-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/sds-user-id" />
            <value value="9999999999" />
        </identifier>
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Condition/Condition-HearingLoss-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient in need of test...example" />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-ServiceRequestUpdate-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-SavedTestOrderWGS-Example

Example of a ServiceRequest. After being saved on the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-SavedTestOrderWGS-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "identifier":  [
        {
            "system": "https://fhir.nhs.uk/Id/GMSOrder",
            "value": "RAS61763"
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-wgs",
                    "display": "Rare Disease - WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R193.4",
                "display": "Cystic renal disease"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-LindsaySorrell-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307946"
        }
    },
    "authoredOn": "2023-08-08",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithRenal-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-MultipleRenalCysts-Example"
        },
        {
            "reference": "Observation/Observation-Nephronophthisis-Example"
        },
        {
            "reference": "Observation/Observation-HepaticCysts-Example"
        },
        {
            "reference": "Observation/Observation-EnlargedKidney-Example"
        },
        {
            "reference": "Observation/Observation-RenalInsufficiency-Example"
        },
        {
            "reference": "Consent/Consent-RoDToFollow-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient diagnoses with ADPKD (example)"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-SavedTestOrderWGS-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <identifier>
        <system value="https://fhir.nhs.uk/Id/GMSOrder" />
        <value value="RAS61763" />
    </identifier>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-wgs" />
            <display value="Rare Disease - WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R193.4" />
            <display value="Cystic renal disease" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-LindsaySorrell-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307946" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-08" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithRenal-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-MultipleRenalCysts-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Nephronophthisis-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-HepaticCysts-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-EnlargedKidney-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RenalInsufficiency-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoDToFollow-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient diagnoses with ADPKD (example)" />
    </note>
</ServiceRequest>

ServiceRequest-TestOrderForm-StorageOfMaterial-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-TestOrderForm-StorageOfMaterial-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R346",
                "display": "DNA to be stored"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-TimMclullichs-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "8449303452"
        }
    },
    "authoredOn": "2023-10-28T11:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-OscarShields-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "1186936003",
                    "display": "Storage of specimen"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        }
    ],
    "note":  [
        {
            "text": "Specimen will be provided at a later date"
        },
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, transplant, life status at time of request details/ E.g. DNA to be stored for future testing"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-TestOrderForm-StorageOfMaterial-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R346" />
            <display value="DNA to be stored" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-TimMclullichs-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="8449303452" />
        </identifier>
    </subject>
    <authoredOn value="2023-10-28T11:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-OscarShields-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="1186936003" />
            <display value="Storage of specimen" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <note>
        <text value="Specimen will be provided at a later date" />
    </note>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, transplant, life status at time of request details/ E.g. DNA to be stored for future testing" />
    </note>
</ServiceRequest>

ServiceRequest-WGSTestOrderForm-DirectToLab-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-WGSTestOrderForm-DirectToLab-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-wgs",
                    "display": "Rare Disease - WGS"
                }
            ]
        }
    ],
    "priority": "urgent",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R14",
                "display": "Acutely unwell children with a likely monogenic disorder"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-JamesMetcalfe-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "7449306524"
        }
    },
    "authoredOn": "2023-10-01T15:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-EugeneSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RH8"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-DiseasePenetrance-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-Immunodefficiency-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Consent/Consent-RoDToFollow-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-JamesMetcalfeBloodEDTA-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms"
        },
        {
            "text": "E.g.  non genetic investigations are pathognomonic of a single gene disorder, R26 previously ordered on the child  and molecular testing needed to guide management"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-WGSTestOrderForm-DirectToLab-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-wgs" />
            <display value="Rare Disease - WGS" />
        </coding>
    </category>
    <priority value="urgent" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R14" />
            <display value="Acutely unwell children with a likely monogenic disorder" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-JamesMetcalfe-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="7449306524" />
        </identifier>
    </subject>
    <authoredOn value="2023-10-01T15:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-EugeneSmith-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RH8" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseasePenetrance-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Immunodefficiency-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoDToFollow-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-JamesMetcalfeBloodEDTA-Example" />
    </specimen>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms" />
    </note>
    <note>
        <text value="E.g.&#160; non genetic investigations are pathognomonic of a single gene disorder, R26 previously ordered on the child&#160; and molecular testing needed to guide management" />
    </note>
</ServiceRequest>

ServiceRequest-WGSTestOrderForm-Example

Example of a ServiceRequest. The scenario this is for is detailed on WGS Test Request - Rare Disease

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-WGSTestOrderForm-Example",
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-wgs",
                    "display": "Rare Disease - WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R193.4",
                "display": "Cystic renal disease"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-LindsaySorrell-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307946"
        }
    },
    "authoredOn": "2023-08-08",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-HazelSmithRenal-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-MultipleRenalCysts-Example"
        },
        {
            "reference": "Observation/Observation-Nephronophthisis-Example"
        },
        {
            "reference": "Observation/Observation-HepaticCysts-Example"
        },
        {
            "reference": "Observation/Observation-EnlargedKidney-Example"
        },
        {
            "reference": "Observation/Observation-RenalInsufficiency-Example"
        },
        {
            "reference": "Consent/Consent-RoDToFollow-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient diagnoses with ADPKD (example)"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-WGSTestOrderForm-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-wgs" />
            <display value="Rare Disease - WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R193.4" />
            <display value="Cystic renal disease" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-LindsaySorrell-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307946" />
        </identifier>
    </subject>
    <authoredOn value="2023-08-08" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-HazelSmithRenal-Example" />
    </requester>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-MultipleRenalCysts-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Nephronophthisis-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-HepaticCysts-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-EnlargedKidney-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-RenalInsufficiency-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoDToFollow-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ Patient diagnoses with ADPKD (example)" />
    </note>
</ServiceRequest>

ServiceRequest-WGSTestOrderForm-TrioTestingProband-Example

Example of a ServiceRequest. After being sent to the central broker, the ServiceRequest is assigned a unique identifier.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-WGSTestOrderForm-TrioTestingProband-Example",
    "identifier":  [
        {
            "system": "https://fhir.leedssth.nhs.uk//Id/grouptestId",
            "value": "RR-REQ12764",
            "assigner": {
                "identifier": {
                    "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                    "value": "RR8"
                }
            }
        }
    ],
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-wgs",
                    "display": "Rare Disease - WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R98.2",
                "display": "Likely inborn error of metabolism"
            }
        ],
        "text": "This is a Trio Testing, comprising 3 family members with their respective specimen`s & Record Of Discussion`s"
    },
    "subject": {
        "reference": "Patient/Patient-PheobeSmitham-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307539"
        }
    },
    "authoredOn": "2023-09-15T15:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-EugeneSmithLeedsSTH-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "R0A"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-DiseasePenetrancePheobeSmitham-Example"
        },
        {
            "reference": "Observation/Observation-IntellectualDisabilityProfound-Example"
        },
        {
            "reference": "Observation/Observation-IntellectualDisabilityMild-Example"
        },
        {
            "reference": "Observation/Observation-AutisticBehaviour-Example"
        },
        {
            "reference": "Observation/Observation-DelayedSpeech-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnionProband-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnionProbandFather-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnionMother-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplantProbandFather-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplantProbandMother-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusionProbandFather-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusionProbandMother-Example"
        },
        {
            "reference": "Specimen/Specimen-PheobeSmitham-Example"
        },
        {
            "reference": "Specimen/Specimen-PheobeSmithamFather-Example"
        },
        {
            "reference": "Specimen/Specimen-PheobeSmithamMother-Example"
        },
        {
            "reference": "Consent/Consent-RoD-PheobeSmitham-Example"
        },
        {
            "reference": "Consent/Consent-RoD-PheobeSmithamMother-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. Not eligible for R14 or R98. Agreed with testing laboratory at Manchester. Father lives in surrey. Father to have sample taken locally and sent to MFT."
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-WGSTestOrderForm-TrioTestingProband-Example" />
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <identifier>
        <system value="https://fhir.leedssth.nhs.uk//Id/grouptestId" />
        <value value="RR-REQ12764" />
        <assigner>
            <identifier>
                <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
                <value value="RR8" />
            </identifier>
        </assigner>
    </identifier>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-wgs" />
            <display value="Rare Disease - WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R98.2" />
            <display value="Likely inborn error of metabolism" />
        </coding>
        <text value="This is a Trio Testing, comprising 3 family members with their respective specimen`s &amp; Record Of Discussion`s" />
    </code>
    <subject>
        <reference value="Patient/Patient-PheobeSmitham-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307539" />
        </identifier>
    </subject>
    <authoredOn value="2023-09-15T15:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-EugeneSmithLeedsSTH-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="R0A" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseasePenetrancePheobeSmitham-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-IntellectualDisabilityProfound-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-IntellectualDisabilityMild-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-AutisticBehaviour-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DelayedSpeech-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnionProband-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnionProbandFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnionMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplantProbandFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplantProbandMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusionProbandFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusionProbandMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-PheobeSmitham-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-PheobeSmithamFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-PheobeSmithamMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoD-PheobeSmitham-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoD-PheobeSmithamMother-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. Not eligible for R14 or R98. Agreed with testing laboratory at Manchester. Father lives in surrey. Father to have sample taken locally and sent to MFT." />
    </note>
</ServiceRequest>

ServiceRequest-WGSTestOrderFormUpdated-DirectToLab-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-WGSTestOrderFormUpdated-DirectToLab-Example",
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-10-10T16:00:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-wgs",
                    "display": "Rare Disease - WGS"
                }
            ]
        }
    ],
    "priority": "urgent",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R14",
                "display": "Acutely unwell children with a likely monogenic disorder"
            }
        ]
    },
    "subject": {
        "reference": "Patient/Patient-JamesMetcalfe-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "7449306524"
        }
    },
    "authoredOn": "2023-10-10T11:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-EugeneSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "RH8"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-DiseasePenetrance-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnion-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-Immunodefficiency-Example"
        },
        {
            "reference": "Observation/Observation-NoTransfusion-Example"
        },
        {
            "reference": "Consent/Consent-RoDYoungPersonAssentFormAvailable-Example"
        }
    ],
    "specimen":  [
        {
            "reference": "Specimen/Specimen-JamesMetcalfeBloodEDTA-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms"
        },
        {
            "text": "E.g.  non genetic investigations are pathognomonic of a single gene disorder, R26 previously ordered on the child  and molecular testing needed to guide management"
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-WGSTestOrderForm-DirectToLab-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-WGSTestOrderFormUpdated-DirectToLab-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-10-10T16:00:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-wgs" />
            <display value="Rare Disease - WGS" />
        </coding>
    </category>
    <priority value="urgent" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R14" />
            <display value="Acutely unwell children with a likely monogenic disorder" />
        </coding>
    </code>
    <subject>
        <reference value="Patient/Patient-JamesMetcalfe-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="7449306524" />
        </identifier>
    </subject>
    <authoredOn value="2023-10-10T11:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-EugeneSmith-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="RH8" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseasePenetrance-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-Immunodefficiency-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoTransfusion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoDYoungPersonAssentFormAvailable-Example" />
    </supportingInfo>
    <specimen>
        <reference value="Specimen/Specimen-JamesMetcalfeBloodEDTA-Example" />
    </specimen>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms" />
    </note>
    <note>
        <text value="E.g.&#160; non genetic investigations are pathognomonic of a single gene disorder, R26 previously ordered on the child&#160; and molecular testing needed to guide management" />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-WGSTestOrderForm-DirectToLab-Example" />
    </relevantHistory>
</ServiceRequest>

ServiceRequest-WGSTestOrderFormUpdated-TrioTesting-Example

Example of a ServiceRequest which has been modified. After modification, the ServiceRequest SHALL include a meta.lastUpdated element and a relevantHitory element referencing the provenance resource detailing the change.

ServiceRequest
{
    "resourceType": "ServiceRequest",
    "id": "ServiceRequest-WGSTestOrderFormUpdated-TrioTesting-Example",
    "meta": {
        "versionId": "2",
        "lastUpdated": "2023-10-09T09:15:00Z"
    },
    "extension":  [
        {
            "url": "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage",
            "valueCodeableConcept": {
                "coding":  [
                    {
                        "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory",
                        "code": "nhs",
                        "display": "NHS"
                    }
                ]
            }
        }
    ],
    "requisition": {
        "assigner": {
            "identifier": {
                "system": "https://fhir.leedsth.nhs.uk/Id/grouptestId",
                "value": "RR8F1792"
            }
        }
    },
    "status": "active",
    "intent": "order",
    "category":  [
        {
            "coding":  [
                {
                    "system": "https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory",
                    "code": "rare-disease-wgs",
                    "display": "Rare Disease - WGS"
                }
            ]
        }
    ],
    "priority": "routine",
    "code": {
        "coding":  [
            {
                "system": "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
                "code": "R98.2",
                "display": "Likely inborn error of metabolism"
            }
        ],
        "text": "This is a Trio Testing, comprising 3 family members with their respective specimen`s & Record Of Discussion`s"
    },
    "subject": {
        "reference": "Patient/Patient-PheobeSmitham-Example",
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9449307539"
        }
    },
    "authoredOn": "2023-09-15T15:00:00Z",
    "requester": {
        "reference": "PractitionerRole/PractitionerRole-EugeneSmith-Example"
    },
    "reasonCode":  [
        {
            "coding":  [
                {
                    "system": "http://snomed.info/sct",
                    "code": "103693007",
                    "display": "Diagnostic procedure"
                }
            ]
        }
    ],
    "performer":  [
        {
            "identifier": {
                "system": "https://fhir.nhs.uk/Id/ods-organization-code",
                "value": "R0A"
            }
        }
    ],
    "supportingInfo":  [
        {
            "reference": "Observation/Observation-GenomicEthnicity-Example"
        },
        {
            "reference": "Observation/Observation-NoPregnancy-Example"
        },
        {
            "reference": "Observation/Observation-DiseaseStatus-Example"
        },
        {
            "reference": "Observation/Observation-DiseasePenetrancePheobeSmitham-Example"
        },
        {
            "reference": "Observation/Observation-IntellectualDisabilityProfound-Example"
        },
        {
            "reference": "Observation/Observation-IntellectualDisabilityMild-Example"
        },
        {
            "reference": "Observation/Observation-AutisticBehaviour-Example"
        },
        {
            "reference": "Observation/Observation-DelayedSpeech-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnionProband-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnionProbandFather-Example"
        },
        {
            "reference": "Observation/Observation-NonConsanguinousUnionMother-Example"
        },
        {
            "reference": "FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplant-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplantProbandFather-Example"
        },
        {
            "reference": "Observation/Observation-NoBoneMarrowTransplantProbandMother-Example"
        },
        {
            "reference": "Specimen/Specimen-PheobeSmitham-Example"
        },
        {
            "reference": "Specimen/Specimen-PheobeSmithamFather-Example"
        },
        {
            "reference": "Specimen/Specimen-PheobeSmithamMother-Example"
        },
        {
            "reference": "Consent/Consent-RoD-PheobeSmitham-Example"
        },
        {
            "reference": "Consent/Consent-RoD-PheobeSmithamMother-Example"
        },
        {
            "reference": "Consent/Consent-RoD-PheobeSmithamFather-Example"
        }
    ],
    "note":  [
        {
            "text": "No family history of genomic testing"
        },
        {
            "text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. Not eligible for R14 or R98. Agreed with testing laboratory at Manchester. Father lives in surrey. Father to have sample taken locally and sent to MFT."
        }
    ],
    "relevantHistory":  [
        {
            "reference": "Provenance/Provenance-WGSTestOrderForm-TrioTestingProbandFather-Example"
        }
    ]
}
<ServiceRequest xmlns="http://hl7.org/fhir">
    <id value="ServiceRequest-WGSTestOrderFormUpdated-TrioTesting-Example" />
    <meta>
        <versionId value="2" />
        <lastUpdated value="2023-10-09T09:15:00Z" />
    </meta>
    <extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage">
        <valueCodeableConcept>
            <coding>
                <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory" />
                <code value="nhs" />
                <display value="NHS" />
            </coding>
        </valueCodeableConcept>
    </extension>
    <requisition>
        <assigner>
            <identifier>
                <system value="https://fhir.leedsth.nhs.uk/Id/grouptestId" />
                <value value="RR8F1792" />
            </identifier>
        </assigner>
    </requisition>
    <status value="active" />
    <intent value="order" />
    <category>
        <coding>
            <system value="https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory" />
            <code value="rare-disease-wgs" />
            <display value="Rare Disease - WGS" />
        </coding>
    </category>
    <priority value="routine" />
    <code>
        <coding>
            <system value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory" />
            <code value="R98.2" />
            <display value="Likely inborn error of metabolism" />
        </coding>
        <text value="This is a Trio Testing, comprising 3 family members with their respective specimen`s &amp; Record Of Discussion`s" />
    </code>
    <subject>
        <reference value="Patient/Patient-PheobeSmitham-Example" />
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9449307539" />
        </identifier>
    </subject>
    <authoredOn value="2023-09-15T15:00:00Z" />
    <requester>
        <reference value="PractitionerRole/PractitionerRole-EugeneSmith-Example" />
    </requester>
    <performer>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/ods-organization-code" />
            <value value="R0A" />
        </identifier>
    </performer>
    <reasonCode>
        <coding>
            <system value="http://snomed.info/sct" />
            <code value="103693007" />
            <display value="Diagnostic procedure" />
        </coding>
    </reasonCode>
    <supportingInfo>
        <reference value="Observation/Observation-GenomicEthnicity-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoPregnancy-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseaseStatus-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DiseasePenetrancePheobeSmitham-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-IntellectualDisabilityProfound-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-IntellectualDisabilityMild-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-AutisticBehaviour-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-DelayedSpeech-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnionProband-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnionProbandFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NonConsanguinousUnionMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="FamilyMemberHistory/FamilyMemberHistory-NonConsanguinousUnion-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplant-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplantProbandFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Observation/Observation-NoBoneMarrowTransplantProbandMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-PheobeSmitham-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-PheobeSmithamFather-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Specimen/Specimen-PheobeSmithamMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoD-PheobeSmitham-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoD-PheobeSmithamMother-Example" />
    </supportingInfo>
    <supportingInfo>
        <reference value="Consent/Consent-RoD-PheobeSmithamFather-Example" />
    </supportingInfo>
    <note>
        <text value="No family history of genomic testing" />
    </note>
    <note>
        <text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. Not eligible for R14 or R98. Agreed with testing laboratory at Manchester. Father lives in surrey. Father to have sample taken locally and sent to MFT." />
    </note>
    <relevantHistory>
        <reference value="Provenance/Provenance-WGSTestOrderForm-TrioTestingProbandFather-Example" />
    </relevantHistory>
</ServiceRequest>