The following changes will be made to the selected profile (and any embeded URLs, like that of extensions) AllergyIntolerance - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-allergyintolerance-1.0.0 Binary - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-binary-1.0.0 Condition - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-condition-1.0.0 DocumentReference - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-documentreference-1.0.0 DocumentReference.content.attachment.Extension - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-documentreference-contentreference-1.0.0 Encounter - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-encounter-1.0.0 Immunization - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-immunization-1.0.0 Location - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-location-1.0.0 MedicationAdministration - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-medicationadministration-1.0.0 Patient.Extension - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-ethnicity-1.0.0 MedicationRequest - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-medicationrequest-1.0.0 Observation - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-observation-1.0.0 Medication - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-medication-1.0.0 Patient - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-patient-1.0.0 Practitioner - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-practitioner-provider-1.0.0 Procedure - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-procedure-1.0.0 QuestionnaireResponse - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-questionnaire-response-social-history-1.0.0 Patient.Extension - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-race-1.0.0 Specimen - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-specimen-1.0.0

The following will be removed Composition - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-composition-clinical-note Composition.section.text.Narrative - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-narrative-clinical-note Composition.section.text.Narrative.Extension - http://deep6.ai/fhir/StructureDefinition/deep-6-ai-clinical-note-text

In addition to the URL changes: • Race and Ethnicity will rely on remote terminology to expand. • Unknown or Refused to Answer valueset is explicitly defined. • SearchParameter and extension for DocumentReference to Binary exists to enforce referential integrity. • Constraint for Encounter.class to always be a V3ActCode. • Binary constraint to enforce non empty Binaries. • Numerous profiles that simply inherit from US core introduced, in order to simplify implementation to always defer to Deep 6 Profiles.