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Sweden
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NPCR_Anmälan_FHIR
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NPCR_Biopsy_Results_Targeted_Biopsy_Observation
Biopsy results observation for prostate tissue obtained via targeted biopsy (MRI-guided). Part of the NPCR biopsy results observation family, consisting of three source-specific profiles (Targeted, Systematic, Unclear). Unlike the Gleason score family (which has 5 profiles including a patient-level Summary), the biopsy results family has no Summary profile — NPCR has no "summary biopsy results" variable group because each biopsy source reports its metrics independently.
Source variables covered (6 NPCR Variabelbeskrivning variables):
- D_AntalRiktBio → component:coresCount (integer)
- D_AntalRiktSaknas → component:coresCountMissing (boolean)
- D_LangstCancer → component:longestCancerLength (decimal, mm)
- D_LangstCancerSakn → component:longestCancerMissing (boolean)
- D_TotBiopsiLangst → component:totalBiopsyOfLongest (decimal, mm)
- D_TotBiopsiLangstSakn → component:totalBiopsyOfLongestMissing (boolean)
Design rationale — targeted-specific metrics: Targeted biopsies measure lesion-focused quantities, unlike systematic biopsies which measure aggregate quantities across all cores. Because MRI-guided targeted sampling aims at specific lesions, NPCR collects "longest cancer lesion in a single biopsy" (D_LangstCancer) and "total biopsy length of the core containing the longest cancer" (D_TotBiopsiLangst). These two metrics enable computation of cancer fraction in the dominant lesion. Unlike systematic/unclear biopsies, targeted biopsies do NOT collect "total cancer mm" or "total biopsy length summed across all cores" in NPCR.
Terminology binding — documentation gap (Observation.code): NPCR Informationsspecifikation §7 does not provide a section for biopsy results identification. Observation.code is Must Support but without fixed value or terminology binding, consistent with other NPCR observation profiles (NPCRMRIFindingsObservation, NPCRGleasonScoreObservation family). Resource identification relies on meta.profile.
Conditional requirements (per NPCR Beteende/logik) — documented but not enforced:
- D_AntalRiktBio is obligatoriskt when D_RiktBiopsi = 1 AND D_AntalRiktSaknas != true
- D_LangstCancer is obligatoriskt when D_RiktBiopsi = 1 AND D_LangstCancerSakn != true
- D_TotBiopsiLangst is obligatoriskt when D_RiktBiopsi = 1 AND D_TotBiopsiLangstSakn != true
- type Profile on Observation
- FHIR R4
- status Draft
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