DeepLearningInteractiveVis (VIS)

Executive summary

This algorithm detects Alzheimer's disease and visualize contributing brain regions with high relevance. Further details on the procedures including samples, image processing, neural network modeling, evaluation, and validation can be seen in published references below.

Resource Overview

Resource Name FHIR Resource Type Link to profile Link to example
VIS Algorithm Device Link Link
VIS Service HealthcareService Link Link
VIS Endpoint Endpoint Link Link
Input Parameter Link Link
Output Parameter Link Link

References

  • Github: https://github.com/martindyrba/DeepLearningInteractiveVis
  • Dyrba et al. (2021) Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer’s disease. Alzheimer's research & therapy 13. DOI: 10.1186/s13195-021-00924-2.

Description

Description

The interactive relevance map visualization application displays brain areas that contribute to the model’s decision. For the task to dectect Alzheimer’s disease, high relevance (shown in red) corresponds to disease-specific gray matter volume reduction (atrophy). Disclaimer: This app is not intended to be used for clinical use and decision making. Although the models achieve a high average accuracy, they are still subject of research. This app is provided for illustration purpose only.

FHIR Model

Profile

definitionI0..1Reference(DeviceDefinition)
statusS Σ ?!1..1codeBinding
statusReason0..*CodeableConceptBinding
distinctIdentifier0..1string
manufacturer0..1string
manufactureDateS0..1dateTime
expirationDate0..1dateTime
lotNumber0..1string
serialNumber0..1string
modelNumber0..1string
partNumber0..1string
type0..1CodeableConcept
patientI0..1Reference(Patient)
ownerS I0..1Reference(OmiOrganization)
locationI0..1Reference(Location)
url0..1uri
safetyΣ0..*CodeableConcept
parentI0..1Reference(Device)

Example

Device

Input Parameters

Description

Inputs for the InteractiveVIS algorithm contain an DICOM image series and a threshold value (integer).

Profile

Example

Parameters

Output Parameters

Description

VIS outputs a probability for Alzheimers disease.

Profile

Instance

Parameters