Example-GenomicsReport

This shows an example genomics report.

Bundle
Bundle.id[0]genomics-report-request-example
Bundle.meta[0].extension[0].extension[0].url[0]msgId
Bundle.meta[0].extension[0].extension[0].value[0].system[0]https://fhir.synapxe.sg/NamingSystem/msg-id
Bundle.meta[0].extension[0].extension[0].value[0].value[0]GEN-20260729-0001
Bundle.meta[0].extension[0].extension[1].url[0]msgSequenceId
Bundle.meta[0].extension[0].extension[1].value[0].system[0]https://fhir.synapxe.sg/NamingSystem/msg-sequence-id
Bundle.meta[0].extension[0].extension[1].value[0].value[0]1
Bundle.meta[0].extension[0].extension[2].url[0]date
Bundle.meta[0].extension[0].extension[2].value[0]2026-07-29T14:30:00+08:00
Bundle.meta[0].extension[0].url[0]https://fhir.synapxe.sg/StructureDefinition/ext-artifact
Bundle.meta[0].source[0]Test_Source
Bundle.meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-bundle-genomicsreport
Bundle.meta[0].tag[0].code[0]Test_Inst
Bundle.type[0]transaction
Bundle.timestamp[0]2026-07-29T06:30:00+00:00
Bundle.entry[0].fullUrl[0]urn:uuid:2a5e8c1d-9b3f-4e2a-7c8d-1f0a2b3c4d5e
Bundle.entry[0].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-genomicsreport
Bundle.entry[0].resource[0].extension[0].url[0]https://fhir.synapxe.sg/StructureDefinition/ext-recommended-action
Bundle.entry[0].resource[0].extension[0].value[0].reference[0]urn:uuid:8f7d6c5e-3a1b-2c9d-0e4f-3a4b5c6d7e8f
Bundle.entry[0].resource[0].extension[0].value[0].type[0]Task
Bundle.entry[0].resource[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/record-id
Bundle.entry[0].resource[0].identifier[0].value[0]GR-2026-07-29-001
Bundle.entry[0].resource[0].identifier[1].system[0]https://fhir.synapxe.sg/NamingSystem/accession-no
Bundle.entry[0].resource[0].identifier[1].value[0]ACC-2026-07-29-001
Bundle.entry[0].resource[0].basedOn[0].reference[0]urn:uuid:3c2b7e9f-1a4d-8c5e-2f3a-9d0e1f2a3b4c
Bundle.entry[0].resource[0].basedOn[0].type[0]ServiceRequest
Bundle.entry[0].resource[0].status[0]final
Bundle.entry[0].resource[0].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[0].resource[0].code[0].coding[0].code[0]51969-4
Bundle.entry[0].resource[0].code[0].coding[0].display[0]Genetic analysis report
Bundle.entry[0].resource[0].subject[0].reference[0]urn:uuid:5b4c7a1e-2f8d-4c9e-6b3a-8f1d2e3c4d5f
Bundle.entry[0].resource[0].subject[0].type[0]Patient
Bundle.entry[0].resource[0].issued[0]2026-07-29T06:30:00+00:00
Bundle.entry[0].resource[0].performer[0].type[0]Organization
Bundle.entry[0].resource[0].performer[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/hci-code
Bundle.entry[0].resource[0].performer[0].identifier[0].value[0]HCI-98765
Bundle.entry[0].resource[0].resultsInterpreter[0].type[0]Practitioner
Bundle.entry[0].resource[0].resultsInterpreter[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/mcr
Bundle.entry[0].resource[0].resultsInterpreter[0].identifier[0].value[0]M45678
Bundle.entry[0].resource[0].specimen[0].reference[0]urn:uuid:4e7a2c1f-8b3d-5f9e-1c4a-9d2e3f4a5b6c
Bundle.entry[0].resource[0].specimen[0].type[0]Specimen
Bundle.entry[0].resource[0].result[0].reference[0]urn:uuid:6d5e3c7f-1a8b-9c2d-4e5f-1a2b3c4d5e6f
Bundle.entry[0].resource[0].result[0].type[0]Observation
Bundle.entry[0].resource[0].result[1].reference[0]urn:uuid:7e6f4d8a-2b9c-0d3e-5f6a-2b3c4d5e6f7a
Bundle.entry[0].resource[0].result[1].type[0]Observation
Bundle.entry[0].request[0].method[0]POST
Bundle.entry[0].request[0].url[0]DiagnosticReport
Bundle.entry[1].fullUrl[0]urn:uuid:6d5e3c7f-1a8b-9c2d-4e5f-1a2b3c4d5e6f
Bundle.entry[1].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-variant
Bundle.entry[1].resource[0].status[0]final
Bundle.entry[1].resource[0].category[0].coding[0].system[0]http://terminology.hl7.org/CodeSystem/observation-category
Bundle.entry[1].resource[0].category[0].coding[0].code[0]laboratory
Bundle.entry[1].resource[0].category[0].coding[0].display[0]Laboratory
Bundle.entry[1].resource[0].category[1].coding[0].system[0]http://terminology.hl7.org/CodeSystem/v2-0074
Bundle.entry[1].resource[0].category[1].coding[0].code[0]GE
Bundle.entry[1].resource[0].category[1].coding[0].display[0]Genetics
Bundle.entry[1].resource[0].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[1].resource[0].code[0].coding[0].code[0]69548-6
Bundle.entry[1].resource[0].code[0].coding[0].display[0]Genetic variation - BRCA1
Bundle.entry[1].resource[0].component[0].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[1].resource[0].component[0].code[0].coding[0].code[0]48018-6
Bundle.entry[1].resource[0].component[0].code[0].coding[0].display[0]Gene symbol
Bundle.entry[1].resource[0].component[0].value[0].coding[0].system[0]http://www.genenames.org
Bundle.entry[1].resource[0].component[0].value[0].coding[0].code[0]HGNC:1100
Bundle.entry[1].resource[0].component[0].value[0].coding[0].display[0]BRCA1
Bundle.entry[1].resource[0].component[1].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[1].resource[0].component[1].code[0].coding[0].code[0]48004-6
Bundle.entry[1].resource[0].component[1].code[0].coding[0].display[0]DNA change (c.HGVS)
Bundle.entry[1].resource[0].component[1].value[0].coding[0].system[0]http://varnomen.hgvs.org
Bundle.entry[1].resource[0].component[1].value[0].coding[0].code[0]c.68_69delAG
Bundle.entry[1].resource[0].component[1].value[0].coding[0].display[0]c.68_69delAG (p.E23Vfs*17)
Bundle.entry[1].resource[0].component[2].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[1].resource[0].component[2].code[0].coding[0].code[0]53034-5
Bundle.entry[1].resource[0].component[2].code[0].coding[0].display[0]Allelic state
Bundle.entry[1].resource[0].component[2].value[0]Heterozygous
Bundle.entry[1].resource[0].component[3].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[1].resource[0].component[3].code[0].coding[0].code[0]53037-8
Bundle.entry[1].resource[0].component[3].code[0].coding[0].display[0]Clinical significance
Bundle.entry[1].resource[0].component[3].value[0]Pathogenic
Bundle.entry[1].request[0].method[0]POST
Bundle.entry[1].request[0].url[0]Observation
Bundle.entry[2].fullUrl[0]urn:uuid:7e6f4d8a-2b9c-0d3e-5f6a-2b3c4d5e6f7a
Bundle.entry[2].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-molecularbiomarker
Bundle.entry[2].resource[0].status[0]final
Bundle.entry[2].resource[0].category[0].coding[0].system[0]http://terminology.hl7.org/CodeSystem/observation-category
Bundle.entry[2].resource[0].category[0].coding[0].code[0]laboratory
Bundle.entry[2].resource[0].category[0].coding[0].display[0]Laboratory
Bundle.entry[2].resource[0].category[1].coding[0].system[0]http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
Bundle.entry[2].resource[0].category[1].coding[0].code[0]biomarker-category
Bundle.entry[2].resource[0].category[1].coding[0].display[0]A characterization of a given biomarker observation.
Bundle.entry[2].resource[0].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[2].resource[0].code[0].coding[0].code[0]48676-1
Bundle.entry[2].resource[0].code[0].coding[0].display[0]Molecular biomarker
Bundle.entry[2].resource[0].component[0].code[0].coding[0].system[0]http://loinc.org
Bundle.entry[2].resource[0].component[0].code[0].coding[0].code[0]48018-6
Bundle.entry[2].resource[0].component[0].code[0].coding[0].display[0]Gene symbol
Bundle.entry[2].resource[0].component[0].value[0].coding[0].system[0]http://www.genenames.org
Bundle.entry[2].resource[0].component[0].value[0].coding[0].code[0]HGNC:1100
Bundle.entry[2].resource[0].component[0].value[0].coding[0].display[0]BRCA1
Bundle.entry[2].resource[0].component[1].code[0].coding[0].system[0]http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
Bundle.entry[2].resource[0].component[1].code[0].coding[0].code[0]specimen-condition
Bundle.entry[2].resource[0].component[1].code[0].coding[0].display[0]Specimen Condition
Bundle.entry[2].resource[0].component[1].value[0]2.5 fold change
Bundle.entry[2].request[0].method[0]POST
Bundle.entry[2].request[0].url[0]Observation
Bundle.entry[3].fullUrl[0]urn:uuid:4e7a2c1f-8b3d-5f9e-1c4a-9d2e3f4a5b6c
Bundle.entry[3].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-genomics-specimen
Bundle.entry[3].resource[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/specimen-id
Bundle.entry[3].resource[0].identifier[0].value[0]SP-2026-07-27-001
Bundle.entry[3].resource[0].collection[0].collected[0]2026-07-27T06:00:00+00:00
Bundle.entry[3].request[0].method[0]POST
Bundle.entry[3].request[0].url[0]Specimen
Bundle.entry[4].fullUrl[0]urn:uuid:3c2b7e9f-1a4d-8c5e-2f3a-9d0e1f2a3b4c
Bundle.entry[4].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-genomics-servicerequest
Bundle.entry[4].resource[0].extension[0].url[0]https://fhir.synapxe.sg/StructureDefinition/ext-order-received-date
Bundle.entry[4].resource[0].extension[0].value[0]2026-07-20T02:00:00+00:00
Bundle.entry[4].resource[0].status[0]active
Bundle.entry[4].resource[0].intent[0]order
Bundle.entry[4].resource[0].code[0].concept[0].coding[0].system[0]http://loinc.org
Bundle.entry[4].resource[0].code[0].concept[0].coding[0].code[0]47528-5
Bundle.entry[4].resource[0].code[0].concept[0].coding[0].display[0]Genetic testing
Bundle.entry[4].resource[0].code[0].concept[0].text[0]Genetic testing
Bundle.entry[4].resource[0].subject[0].reference[0]urn:uuid:5b4c7a1e-2f8d-4c9e-6b3a-8f1d2e3c4d5f
Bundle.entry[4].resource[0].subject[0].type[0]Patient
Bundle.entry[4].resource[0].authoredOn[0]2026-07-20T02:00:00+00:00
Bundle.entry[4].resource[0].requester[0].type[0]Practitioner
Bundle.entry[4].resource[0].requester[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/mcr
Bundle.entry[4].resource[0].requester[0].identifier[0].value[0]M34567
Bundle.entry[4].request[0].method[0]POST
Bundle.entry[4].request[0].url[0]ServiceRequest
Bundle.entry[5].fullUrl[0]urn:uuid:5b4c7a1e-2f8d-4c9e-6b3a-8f1d2e3c4d5f
Bundle.entry[5].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-genomics-patient
Bundle.entry[5].resource[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/nric
Bundle.entry[5].resource[0].identifier[0].value[0]S9876543D
Bundle.entry[5].resource[0].name[0].text[0]Jane Doe
Bundle.entry[5].resource[0].gender[0]female
Bundle.entry[5].resource[0].birthDate[0]1980-05-15
Bundle.entry[5].request[0].method[0]POST
Bundle.entry[5].request[0].url[0]Patient
Bundle.entry[6].fullUrl[0]urn:uuid:8f7d6c5e-3a1b-2c9d-0e4f-3a4b5c6d7e8f
Bundle.entry[6].resource[0].meta[0].profile[0]https://fhir.synapxe.sg/StructureDefinition/profile-medicationrecommendation
Bundle.entry[6].resource[0].status[0]requested
Bundle.entry[6].resource[0].intent[0]proposal
Bundle.entry[6].resource[0].code[0].coding[0].system[0]https://fhir.synapxe.sg/CodeSystem/medicationrecommendation-code
Bundle.entry[6].resource[0].code[0].coding[0].code[0]clinical-protocol
Bundle.entry[6].resource[0].code[0].coding[0].display[0]Clinical Protocol
Bundle.entry[6].resource[0].description[0]Consider prophylactic hormone therapy or preventive mastectomy. Genetic counseling recommended for family members.
Bundle.entry[6].resource[0].focus[0].type[0]MedicationStatement
Bundle.entry[6].resource[0].focus[0].identifier[0].system[0]https://fhir.synapxe.sg/NamingSystem/medication-statement-id
Bundle.entry[6].resource[0].focus[0].identifier[0].value[0]MS-BRCA1-PREVENTIVE-001
Bundle.entry[6].request[0].method[0]POST
Bundle.entry[6].request[0].url[0]Task
{
"resourceType": "Bundle",
"id": "genomics-report-request-example",
"meta": {
{
{
"url": "msgId",
"system": "https://fhir.synapxe.sg/NamingSystem/msg-id",
"value": "GEN-20260729-0001"
}
},
{
"url": "msgSequenceId",
"system": "https://fhir.synapxe.sg/NamingSystem/msg-sequence-id",
"value": "1"
}
},
{
"url": "date",
"valueDateTime": "2026-07-29T14:30:00+08:00"
}
],
"url": "https://fhir.synapxe.sg/StructureDefinition/ext-artifact"
}
],
"source": "Test_Source",
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-bundle-genomicsreport"
],
"tag": [
{
"code": "Test_Inst"
}
]
},
"type": "transaction",
"timestamp": "2026-07-29T06:30:00+00:00",
"entry": [
{
"fullUrl": "urn:uuid:2a5e8c1d-9b3f-4e2a-7c8d-1f0a2b3c4d5e",
"resourceType": "DiagnosticReport",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-genomicsreport"
]
},
{
"url": "https://fhir.synapxe.sg/StructureDefinition/ext-recommended-action",
"reference": "urn:uuid:8f7d6c5e-3a1b-2c9d-0e4f-3a4b5c6d7e8f",
"type": "Task"
}
}
],
{
"system": "https://fhir.synapxe.sg/NamingSystem/record-id",
"value": "GR-2026-07-29-001"
},
{
"system": "https://fhir.synapxe.sg/NamingSystem/accession-no",
"value": "ACC-2026-07-29-001"
}
],
"basedOn": [
{
"reference": "urn:uuid:3c2b7e9f-1a4d-8c5e-2f3a-9d0e1f2a3b4c",
"type": "ServiceRequest"
}
],
"status": "final",
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "51969-4",
"display": "Genetic analysis report"
}
]
},
"subject": {
"reference": "urn:uuid:5b4c7a1e-2f8d-4c9e-6b3a-8f1d2e3c4d5f",
"type": "Patient"
},
"issued": "2026-07-29T06:30:00+00:00",
{
"type": "Organization",
"system": "https://fhir.synapxe.sg/NamingSystem/hci-code",
"value": "HCI-98765"
}
}
],
{
"type": "Practitioner",
"system": "https://fhir.synapxe.sg/NamingSystem/mcr",
"value": "M45678"
}
}
],
{
"reference": "urn:uuid:4e7a2c1f-8b3d-5f9e-1c4a-9d2e3f4a5b6c",
"type": "Specimen"
}
],
"result": [
{
"reference": "urn:uuid:6d5e3c7f-1a8b-9c2d-4e5f-1a2b3c4d5e6f",
"type": "Observation"
},
{
"reference": "urn:uuid:7e6f4d8a-2b9c-0d3e-5f6a-2b3c4d5e6f7a",
"type": "Observation"
}
]
},
"request": {
"method": "POST",
"url": "DiagnosticReport"
}
},
{
"fullUrl": "urn:uuid:6d5e3c7f-1a8b-9c2d-4e5f-1a2b3c4d5e6f",
"resourceType": "Observation",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-variant"
]
},
"status": "final",
{
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/observation-category",
"code": "laboratory",
"display": "Laboratory"
}
]
},
{
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/v2-0074",
"code": "GE",
"display": "Genetics"
}
]
}
],
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "69548-6",
"display": "Genetic variation - BRCA1"
}
]
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "48018-6",
"display": "Gene symbol"
}
]
},
"coding": [
{
"system": "http://www.genenames.org",
"code": "HGNC:1100",
"display": "BRCA1"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "48004-6",
"display": "DNA change (c.HGVS)"
}
]
},
"coding": [
{
"system": "http://varnomen.hgvs.org",
"code": "c.68_69delAG",
"display": "c.68_69delAG (p.E23Vfs*17)"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "53034-5",
"display": "Allelic state"
}
]
},
"valueString": "Heterozygous"
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "53037-8",
"display": "Clinical significance"
}
]
},
"valueString": "Pathogenic"
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"fullUrl": "urn:uuid:7e6f4d8a-2b9c-0d3e-5f6a-2b3c4d5e6f7a",
"resourceType": "Observation",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-molecularbiomarker"
]
},
"status": "final",
{
"coding": [
{
"system": "http://terminology.hl7.org/CodeSystem/observation-category",
"code": "laboratory",
"display": "Laboratory"
}
]
},
{
"coding": [
{
"system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
"code": "biomarker-category",
"display": "A characterization of a given biomarker observation."
}
]
}
],
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "48676-1",
"display": "Molecular biomarker"
}
]
},
{
"code": {
"coding": [
{
"system": "http://loinc.org",
"code": "48018-6",
"display": "Gene symbol"
}
]
},
"coding": [
{
"system": "http://www.genenames.org",
"code": "HGNC:1100",
"display": "BRCA1"
}
]
}
},
{
"code": {
"coding": [
{
"system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs",
"code": "specimen-condition",
"display": "Specimen Condition"
}
]
},
"valueString": "2.5 fold change"
}
]
},
"request": {
"method": "POST",
"url": "Observation"
}
},
{
"fullUrl": "urn:uuid:4e7a2c1f-8b3d-5f9e-1c4a-9d2e3f4a5b6c",
"resourceType": "Specimen",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-genomics-specimen"
]
},
{
"system": "https://fhir.synapxe.sg/NamingSystem/specimen-id",
"value": "SP-2026-07-27-001"
}
],
"collectedDateTime": "2026-07-27T06:00:00+00:00"
}
},
"request": {
"method": "POST",
"url": "Specimen"
}
},
{
"fullUrl": "urn:uuid:3c2b7e9f-1a4d-8c5e-2f3a-9d0e1f2a3b4c",
"resourceType": "ServiceRequest",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-genomics-servicerequest"
]
},
{
"url": "https://fhir.synapxe.sg/StructureDefinition/ext-order-received-date",
"valueDateTime": "2026-07-20T02:00:00+00:00"
}
],
"status": "active",
"intent": "order",
"code": {
"concept": {
"coding": [
{
"system": "http://loinc.org",
"code": "47528-5",
"display": "Genetic testing"
}
],
"text": "Genetic testing"
}
},
"subject": {
"reference": "urn:uuid:5b4c7a1e-2f8d-4c9e-6b3a-8f1d2e3c4d5f",
"type": "Patient"
},
"authoredOn": "2026-07-20T02:00:00+00:00",
"type": "Practitioner",
"system": "https://fhir.synapxe.sg/NamingSystem/mcr",
"value": "M34567"
}
}
},
"request": {
"method": "POST",
"url": "ServiceRequest"
}
},
{
"fullUrl": "urn:uuid:5b4c7a1e-2f8d-4c9e-6b3a-8f1d2e3c4d5f",
"resourceType": "Patient",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-genomics-patient"
]
},
{
"system": "https://fhir.synapxe.sg/NamingSystem/nric",
"value": "S9876543D"
}
],
"name": [
{
"text": "Jane Doe"
}
],
"gender": "female",
"birthDate": "1980-05-15"
},
"request": {
"method": "POST",
"url": "Patient"
}
},
{
"fullUrl": "urn:uuid:8f7d6c5e-3a1b-2c9d-0e4f-3a4b5c6d7e8f",
"resourceType": "Task",
"meta": {
"profile": [
"https://fhir.synapxe.sg/StructureDefinition/profile-medicationrecommendation"
]
},
"status": "requested",
"intent": "proposal",
"code": {
"coding": [
{
"system": "https://fhir.synapxe.sg/CodeSystem/medicationrecommendation-code",
"code": "clinical-protocol",
"display": "Clinical Protocol"
}
]
},
"description": "Consider prophylactic hormone therapy or preventive mastectomy. Genetic counseling recommended for family members.",
"focus": {
"type": "MedicationStatement",
"system": "https://fhir.synapxe.sg/NamingSystem/medication-statement-id",
"value": "MS-BRCA1-PREVENTIVE-001"
}
}
},
"request": {
"method": "POST",
"url": "Task"
}
}
]
}
Command 'narrative' could not render: File is not a DomainResource