MII IG Person DE v2024

Proband:in (ResearchSubject)

package/StructureDefinition-mii-pr-person-proband.json

Beschreibung

Dieses Profil beschreibt eine ProbandIn in der Medizininformatik-Initiative.

Beim Einschluss einer Person in eine Studie (auch in einen MII-Use Case) MUSS für diese Person eine ResearchSubject-Ressource erstellt werden. Es sind folgende Varianten zu unterscheiden:

Der Einschluss erfolgt durch eine spezifische Informierte Einwilligung für eine Studie.
Der Einschluss erfolgt auf der Basis einer Breiten Informierten Einwilligung („Broad Consent“).
Der Einschluss erfolgt auf der Basis einer speziellen gesetzlichen Grundlage (Spezialgesetz wie Landeskrankenhausgesetz, Infektionsschutzgesetz oder Krebsregistergesetz). Dies gilt gleichermaßen für die Personen der Untersuchungsgruppe, der Kontrollgruppe und jeder Form von Referenzpopulation, für die personenbezogene (oder personenbeziehbare) Einzelangaben in Berechnungen einbezogen werden.

Die Erstellung der Ressource MUSS zum Zeitpunkt des Abrufens der Daten für die Studie erfolgen. Weitere Pflichten und Anpassungen sind für jeden Use Case zu prüfen.

Name	Status	Version	Canonical	Basis
MII_PR_Person_Proband	active	2024.0.0	https://www.medizininformatik-initiative.de/fhir/core/modul-person/StructureDefinition/ResearchSubject	http://hl7.org/fhir/StructureDefinition/ResearchSubject

Inhalt

MII_PR_Person_Proband (ResearchSubject)	I		ResearchSubject	There are no (further) constraints on this element Element id ResearchSubject Short description Physical entity which is the primary unit of interest in the study Alternate names Study Subject Definition A physical entity which is the primary unit of operational and/or administrative interest in a study. Comments Need to make sure we encompass public health studies. Data type ResearchSubject Constraints dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources `contained.contained.empty()` dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource `contained.where((('#'+id in (%resource.descendants().reference \| %resource.descendants().as(canonical) \| %resource.descendants().as(uri) \| %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()` dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()` dom-5: If a resource is contained in another resource, it SHALL NOT have a security label `contained.meta.security.empty()` dom-6: A resource should have narrative for robust management text.`div`.exists() Mappings rim: Entity. Role, or Act BRIDG5.1: StudySubject v2: OBX rim: Observation[classCode=CLNTRL, moodCode=EVN]
id	S Σ	0..1	string	There are no (further) constraints on this element Element id ResearchSubject.id Short description Logical id of this artifact Definition The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes. Comments The only time that a resource does not have an id is when it is being submitted to the server using a create operation. Data type string
meta	S Σ	0..1	Meta	There are no (further) constraints on this element Element id ResearchSubject.meta Short description Metadata about the resource Definition The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource. Data type Meta Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
id		0..1	string	There are no (further) constraints on this element Element id ResearchSubject.meta.id Short description Unique id for inter-element referencing Definition Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces. Data type string Mappings rim: n/a
extension	I	0..*	Extension	There are no (further) constraints on this element Element id ResearchSubject.meta.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data type Extension Sliced: Unordered, Open, by url(Value) Extensions are always sliced by (at least) url Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1: Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim: n/a
versionId	Σ	0..1	id	There are no (further) constraints on this element Element id ResearchSubject.meta.versionId Short description Version specific identifier Definition The version specific identifier, as it appears in the version portion of the URL. This value changes when the resource is created, updated, or deleted. Comments The server assigns this value, and ignores what the client specifies, except in the case that the server is imposing version integrity on updates/deletes. Data type id Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
lastUpdated	Σ	0..1	instant	There are no (further) constraints on this element Element id ResearchSubject.meta.lastUpdated Short description When the resource version last changed Definition When the resource last changed - e.g. when the version changed. Comments This value is always populated except when the resource is first being created. The server / resource manager sets this value; what a client provides is irrelevant. This is equivalent to the HTTP Last-Modified and SHOULD have the same value on a read interaction. Data type instant Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
source	Σ	0..1	uri	There are no (further) constraints on this element Element id ResearchSubject.meta.source Short description Identifies where the resource comes from Definition A uri that identifies the source system of the resource. This provides a minimal amount of Provenance information that can be used to track or differentiate the source of information in the resource. The source may identify another FHIR server, document, message, database, etc. Comments In the provenance resource, this corresponds to Provenance.entity.what[x]. The exact use of the source (and the implied Provenance.entity.role) is left to implementer discretion. Only one nominated source is allowed; for additional provenance details, a full Provenance resource should be used. This element can be used to indicate where the current master source of a resource that has a canonical URL if the resource is no longer hosted at the canonical URL. Data type uri Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
profile	S Σ	0..*	canonical(StructureDefinition)	There are no (further) constraints on this element Element id ResearchSubject.meta.profile Short description Profiles this resource claims to conform to Definition A list of profiles (references to StructureDefinition resources) that this resource claims to conform to. The URL is a reference to StructureDefinition.url. Comments It is up to the server and/or other infrastructure of policy to determine whether/how these claims are verified and/or updated over time. The list of profile URLs is a set. Data type canonical(StructureDefinition) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
security	Σ	0..*	CodingBinding	There are no (further) constraints on this element Element id ResearchSubject.meta.security Short description Security Labels applied to this resource Definition Security labels applied to this resource. These tags connect specific resources to the overall security policy and infrastructure. Comments The security labels can be updated without changing the stated version of the resource. The list of security labels is a set. Uniqueness is based the system/code, and version and display are ignored. Data type Coding Binding Security Labels from the Healthcare Privacy and Security Classification System. All Security Labels (extensible) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
tag	Σ	0..*	Coding	There are no (further) constraints on this element Element id ResearchSubject.meta.tag Short description Tags applied to this resource Definition Tags applied to this resource. Tags are intended to be used to identify and relate resources to process and workflow, and applications are not required to consider the tags when interpreting the meaning of a resource. Comments The tags can be updated without changing the stated version of the resource. The list of tags is a set. Uniqueness is based the system/code, and version and display are ignored. Data type Coding Binding Codes that represent various types of tags, commonly workflow-related; e.g. "Needs review by Dr. Jones". CommonTags (example) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
implicitRules	Σ ?!	0..1	uri	There are no (further) constraints on this element Element id ResearchSubject.implicitRules Short description A set of rules under which this content was created Definition A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc. Comments Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc. Data type uri Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
language		0..1	codeBinding	There are no (further) constraints on this element Element id ResearchSubject.language Short description Language of the resource content Definition The base language in which the resource is written. Comments Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute). Data type code Binding A human language. CommonLanguages (preferred) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())`
text		0..1	Narrative	There are no (further) constraints on this element Element id ResearchSubject.text Short description Text summary of the resource, for human interpretation Alternate names narrative, html, xhtml, display Definition A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety. Comments Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later. Data type Narrative Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim: Act.text?
contained		0..*	Resource	There are no (further) constraints on this element Element id ResearchSubject.contained Short description Contained, inline Resources Alternate names inline resources, anonymous resources, contained resources Definition These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope. Comments This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels. Data type Resource Mappings rim: N/A
extension	I	0..*	Extension	There are no (further) constraints on this element Element id ResearchSubject.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data type Extension Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1: Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim: N/A
modifierExtension	?! I	0..*	Extension	There are no (further) constraints on this element Element id ResearchSubject.modifierExtension Short description Extensions that cannot be ignored Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself). Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data type Extension Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1: Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim: N/A
identifier	S Σ	1..*	Identifier	Element id ResearchSubject.identifier Short description Business Identifier for research subject in a study Definition Identifiers assigned to this research subject for a study. Data type Identifier Sliced: Unordered, Open, by $this(Pattern) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings w5: FiveWs.identifier BRIDG5.1: StudySubject > Subject.identifier rim: .identifier
subjectIdentificationCode	S Σ	1..1	IdentifierPattern	Element id ResearchSubject.identifier:subjectIdentificationCode Short description Business Identifier for research subject in a study Definition Identifiers assigned to this research subject for a study. Data type Identifier Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Pattern { "type": { "coding": [ { "system": "http://terminology.hl7.org/CodeSystem/v2-0203", "code": "ANON" } ] } } Mappings w5: FiveWs.identifier BRIDG5.1: StudySubject > Subject.identifier rim: .identifier
id		0..1	string	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.id Short description Unique id for inter-element referencing Definition Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces. Data type string Mappings rim: n/a
extension	I	0..*	Extension	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data type Extension Sliced: Unordered, Open, by url(Value) Extensions are always sliced by (at least) url Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1: Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim: n/a
use	Σ ?!	0..1	codeBinding	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.use Short description usual \| official \| temp \| secondary \| old (If known) Definition The purpose of this identifier. Requirements Allows the appropriate identifier for a particular context of use to be selected from among a set of identifiers. Comments Applications can assume that an identifier is permanent unless it explicitly says that it is temporary. Data type code Binding Identifies the purpose for this identifier, if known . IdentifierUse (required) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings v2: N/A rim: Role.code or implied by context
type	S Σ	0..1	CodeableConceptBindingPattern	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.type Short description Description of identifier Definition A coded type for the identifier that can be used to determine which identifier to use for a specific purpose. Requirements Allows users to make use of identifiers when the identifier system is not known. Comments This element deals only with general categories of identifiers. It SHOULD not be used for codes that correspond 1..1 with the Identifier.system. Some identifiers may fall into multiple categories due to common usage. Where the system is known, a type is unnecessary because the type is always part of the system definition. However systems often need to handle identifiers where the system is not known. There is not a 1:1 relationship between type and system, since many different systems have the same type. Data type CodeableConcept Binding A coded type for an identifier that can be used to determine which identifier to use for a specific purpose. Identifier Type Codes (extensible) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Pattern { "coding": [ { "system": "http://terminology.hl7.org/CodeSystem/v2-0203", "code": "ANON" } ] } Mappings v2: CX.5 rim: Role.code or implied by context
system	S Σ	1..1	uri	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.system Short description The namespace for the identifier value Definition Establishes the namespace for the value - that is, a URL that describes a set values that are unique. Requirements There are many sets of identifiers. To perform matching of two identifiers, we need to know what set we're dealing with. The system identifies a particular set of unique identifiers. Comments Identifier.system is always case sensitive. Data type uri Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Examples General http://www.acme.com/identifiers/patient Mappings v2: CX.4 / EI-2-4 rim: II.root or Role.id.root servd: ./IdentifierType
value	S Σ	1..1	string	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.value Short description The value that is unique Definition The portion of the identifier typically relevant to the user and which is unique within the context of the system. Comments If the value is a full URI, then the system SHALL be urn:ietf:rfc:3986. The value's primary purpose is computational mapping. As a result, it may be normalized for comparison purposes (e.g. removing non-significant whitespace, dashes, etc.) A value formatted for human display can be conveyed using the Rendered Value extension. Identifier.value is to be treated as case sensitive unless knowledge of the Identifier.system allows the processer to be confident that non-case-sensitive processing is safe. Data type string Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Examples General 123456 Mappings v2: CX.1 / EI.1 rim: II.extension or II.root if system indicates OID or GUID (Or Role.id.extension or root) servd: ./Value
period	Σ	0..1	Period	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.period Short description Time period when id is/was valid for use Definition Time period during which identifier is/was valid for use. Data type Period Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings v2: CX.7 + CX.8 rim: Role.effectiveTime or implied by context servd: ./StartDate and ./EndDate
assigner	Σ	0..1	Reference(Organization)	There are no (further) constraints on this element Element id ResearchSubject.identifier:subjectIdentificationCode.assigner Short description Organization that issued id (may be just text) Definition Organization that issued/manages the identifier. Comments The Identifier.assigner may omit the .reference element and only contain a .display element reflecting the name or other textual information about the assigning organization. Data type Reference(Organization) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings v2: CX.4 / (CX.4,CX.9,CX.10) rim: II.assigningAuthorityName but note that this is an improper use by the definition of the field. Also Role.scoper servd: ./IdentifierIssuingAuthority
status	S Σ ?!	1..1	codeBinding	There are no (further) constraints on this element Element id ResearchSubject.status Short description candidate \| eligible \| follow-up \| ineligible \| not-registered \| off-study \| on-study \| on-study-intervention \| on-study-observation \| pending-on-study \| potential-candidate \| screening \| withdrawn Definition The current state of the subject. Data type code Binding Indicates the progression of a study subject through a study. ResearchSubjectStatus (required) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings w5: FiveWs.status BRIDG5.1: StudySubject.statusCode rim: .status
period	S Σ	1..1	Period	There are no (further) constraints on this element Element id ResearchSubject.period Short description Start and end of participation Alternate names timing Definition The dates the subject began and ended their participation in the study. Data type Period Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings w5: FiveWs.planned BRIDG5.1: PerformedStudySubjectMilestone.studyReferenceDateRange
id		0..1	string	There are no (further) constraints on this element Element id ResearchSubject.period.id Short description Unique id for inter-element referencing Definition Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces. Data type string Mappings rim: n/a
extension	I	0..*	Extension	There are no (further) constraints on this element Element id ResearchSubject.period.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data type Extension Sliced: Unordered, Open, by url(Value) Extensions are always sliced by (at least) url Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1: Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim: n/a
start	S Σ I	1..1	dateTime	There are no (further) constraints on this element Element id ResearchSubject.period.start Short description Starting time with inclusive boundary Definition The start of the period. The boundary is inclusive. Comments If the low element is missing, the meaning is that the low boundary is not known. Data type dateTime Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings v2: DR.1 rim: ./low
end	S Σ I	0..1	dateTime	There are no (further) constraints on this element Element id ResearchSubject.period.end Short description End time with inclusive boundary, if not ongoing Definition The end of the period. If the end of the period is missing, it means no end was known or planned at the time the instance was created. The start may be in the past, and the end date in the future, which means that period is expected/planned to end at that time. Comments The high value includes any matching date/time. i.e. 2012-02-03T10:00:00 is in a period that has an end value of 2012-02-03. Meaning when missing If the end of the period is missing, it means that the period is ongoing Data type dateTime Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings v2: DR.2 rim: ./high
study	S Σ	1..1	Reference(ResearchStudy)	There are no (further) constraints on this element Element id ResearchSubject.study Short description Study subject is part of Definition Reference to the study the subject is participating in. Data type Reference(ResearchStudy) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings BRIDG5.1: StudySubjectProtocolVersionRelationship
individual	S Σ	1..1	Reference(Patient)	There are no (further) constraints on this element Element id ResearchSubject.individual Short description Who is part of study Definition The record of the person or animal who is involved in the study. Data type Reference(Patient) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings BRIDG5.1: StudySubject
assignedArm		0..1	string	There are no (further) constraints on this element Element id ResearchSubject.assignedArm Short description What path should be followed Definition The name of the arm in the study the subject is expected to follow as part of this study. Data type string Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings BRIDG5.1: Arm > ExperimentalUnit > BiologicEntity > Subject > StudySubject
actualArm		0..1	string	There are no (further) constraints on this element Element id ResearchSubject.actualArm Short description What path was followed Definition The name of the arm in the study the subject actually followed as part of this study. Data type string Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings BRIDG5.1: Arm > ExperimentalUnit > BiologicEntity > Subject > StudySubject
consent	S	1..1	Reference(Consent)	There are no (further) constraints on this element Element id ResearchSubject.consent Short description Agreement to participate in study Definition A record of the patient's informed agreement to participate in the study. Data type Reference(Consent) Constraints ele-1: All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings BRIDG5.1: ResearchStudy.consent is related to PerformedStudySubjectMilestone.informedConsentIndicator in that the informedConsentIndicator can be derived from the data in the Consent resource.

Dieses Profil beschreibt eine Proband*in in der Medizininformatik-Initiative.

Feldname
ResearchSubject.id
ResearchSubject.meta
ResearchSubject.meta.profile
ResearchSubject.identifier
ResearchSubject.identifier:subjectIdentificationCode
ResearchSubject.identifier:subjectIdentificationCode.type
ResearchSubject.identifier:subjectIdentificationCode.system
ResearchSubject.identifier:subjectIdentificationCode.value
ResearchSubject.status
ResearchSubject.period
ResearchSubject.period.start
ResearchSubject.period.end
ResearchSubject.study
ResearchSubject.individual
ResearchSubject.consent

<StructureDefinition xmlns="http://hl7.org/fhir">
    <id value="mii-pr-person-proband" />
    <url value="https://www.medizininformatik-initiative.de/fhir/core/modul-person/StructureDefinition/ResearchSubject" />
    <version value="2024.0.0" />
    <name value="MII_PR_Person_Proband" />
    <title value="MII PR Person Proband" />
    <status value="active" />
    <date value="2024-02-08" />
    <publisher value="Medizininformatik Initiative" />
    <contact>
        <telecom>
            <system value="url" />
            <value value="https://www.medizininformatik-initiative.de" />
        </telecom>
    </contact>
    <description value="Dieses Profil beschreibt eine Proband*in in der Medizininformatik-Initiative." />
    <fhirVersion value="4.0.1" />
    <kind value="resource" />
    <abstract value="false" />
    <type value="ResearchSubject" />
    <baseDefinition value="http://hl7.org/fhir/StructureDefinition/ResearchSubject" />
    <derivation value="constraint" />
    <differential>
        <element id="ResearchSubject.id">
            <path value="ResearchSubject.id" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.meta">
            <path value="ResearchSubject.meta" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.meta.profile">
            <path value="ResearchSubject.meta.profile" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.identifier">
            <path value="ResearchSubject.identifier" />
            <slicing>
                <discriminator>
                    <type value="pattern" />
                    <path value="$this" />
                </discriminator>
                <rules value="open" />
            </slicing>
            <min value="1" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.identifier:subjectIdentificationCode">
            <path value="ResearchSubject.identifier" />
            <sliceName value="subjectIdentificationCode" />
            <min value="1" />
            <max value="1" />
            <patternIdentifier>
                <type>
                    <coding>
                        <system value="http://terminology.hl7.org/CodeSystem/v2-0203" />
                        <code value="ANON" />
                    </coding>
                </type>
            </patternIdentifier>
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.identifier:subjectIdentificationCode.type">
            <path value="ResearchSubject.identifier.type" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.identifier:subjectIdentificationCode.system">
            <path value="ResearchSubject.identifier.system" />
            <min value="1" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.identifier:subjectIdentificationCode.value">
            <path value="ResearchSubject.identifier.value" />
            <min value="1" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.status">
            <path value="ResearchSubject.status" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.period">
            <path value="ResearchSubject.period" />
            <min value="1" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.period.start">
            <path value="ResearchSubject.period.start" />
            <min value="1" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.period.end">
            <path value="ResearchSubject.period.end" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.study">
            <path value="ResearchSubject.study" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.individual">
            <path value="ResearchSubject.individual" />
            <mustSupport value="true" />
        </element>
        <element id="ResearchSubject.consent">
            <path value="ResearchSubject.consent" />
            <min value="1" />
            <mustSupport value="true" />
        </element>
    </differential>
</StructureDefinition>

{
    "resourceType": "StructureDefinition",
    "id": "mii-pr-person-proband",
    "url": "https://www.medizininformatik-initiative.de/fhir/core/modul-person/StructureDefinition/ResearchSubject",
    "version": "2024.0.0",
    "name": "MII_PR_Person_Proband",
    "title": "MII PR Person Proband",
    "status": "active",
    "date": "2024-02-08",
    "publisher": "Medizininformatik Initiative",
    "contact":  [
        {
            "telecom":  [
                {
                    "system": "url",
                    "value": "https://www.medizininformatik-initiative.de"
                }
            ]
        }
    ],
    "description": "Dieses Profil beschreibt eine Proband*in in der Medizininformatik-Initiative.",
    "fhirVersion": "4.0.1",
    "kind": "resource",
    "abstract": false,
    "type": "ResearchSubject",
    "baseDefinition": "http://hl7.org/fhir/StructureDefinition/ResearchSubject",
    "derivation": "constraint",
    "differential": {
        "element":  [
            {
                "id": "ResearchSubject.id",
                "path": "ResearchSubject.id",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.meta",
                "path": "ResearchSubject.meta",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.meta.profile",
                "path": "ResearchSubject.meta.profile",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.identifier",
                "path": "ResearchSubject.identifier",
                "slicing": {
                    "discriminator":  [
                        {
                            "type": "pattern",
                            "path": "$this"
                        }
                    ],
                    "rules": "open"
                },
                "min": 1,
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.identifier:subjectIdentificationCode",
                "path": "ResearchSubject.identifier",
                "sliceName": "subjectIdentificationCode",
                "min": 1,
                "max": "1",
                "patternIdentifier": {
                    "type": {
                        "coding":  [
                            {
                                "code": "ANON",
                                "system": "http://terminology.hl7.org/CodeSystem/v2-0203"
                            }
                        ]
                    }
                },
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.identifier:subjectIdentificationCode.type",
                "path": "ResearchSubject.identifier.type",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.identifier:subjectIdentificationCode.system",
                "path": "ResearchSubject.identifier.system",
                "min": 1,
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.identifier:subjectIdentificationCode.value",
                "path": "ResearchSubject.identifier.value",
                "min": 1,
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.status",
                "path": "ResearchSubject.status",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.period",
                "path": "ResearchSubject.period",
                "min": 1,
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.period.start",
                "path": "ResearchSubject.period.start",
                "min": 1,
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.period.end",
                "path": "ResearchSubject.period.end",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.study",
                "path": "ResearchSubject.study",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.individual",
                "path": "ResearchSubject.individual",
                "mustSupport": true
            },
            {
                "id": "ResearchSubject.consent",
                "path": "ResearchSubject.consent",
                "min": 1,
                "mustSupport": true
            }
        ]
    }
}

package/StructureDefinition-mii-pr-person-proband.json

Hinweise

FHIR-Element	Erklärung
ResearchSubject.id	Must-support, jedoch optional
ResearchSubject.meta	Must-support, jedoch optional
ResearchSubject.meta.profile	VERPFLICHTEND für die Abfrage im DIZ-Repsoitory inkl Versionsnummer des Profils. Siehe CapabilityStatement. In allen anderen Fällen optional.
Patient.identifier:subjectIdentificationCode	Fixes NamingSystem zur einheitlichen, standort-übergreifenden Abfrage des Identifiers (bei Auswertungen)
ResearchSubject.period.start	Startdatum (Einschluss der PatientIn in die Studie)
ResearchSubject.period.end	Enddatum (Abschluss der Studie oder Ausschluss der PatientIn)
ResearchSubject.study	Referenz auf die Metadaten der Studie an welcher die PatientIn teilnimmt. Weitere Vorgaben siehe Erweiterungsmodul STUDIENDATEN.
ResearchSubject.individual	Jede ProbandIn MUSS einer PatientIn zugeordnet werden.
ResearchSubject.consent	Einwilligung in die Studie oder regulatorische Grundlage MUSS vorliegen. Weitere Vorgaben für die Modellierung des Consents können durch andere Erweiterungsmodule entstehen.

Mapping

FHIR-Element	Logischer Datensatz
ResearchSubject.identifier:subjectIdentificationCode	Person.Studienteilnehmer.SubjektIdentifizierungscode
ResearchSubject.status	Person.Studienteilnehmer.StatusDerTeilnahme
ResearchSubject.period.start	Person.Studienteilnehmer.BeginnTeilnahme
ResearchSubject.period.end	Person.Studienteilnehmer.EndeTeilnahme
ResearchSubject.consent	Person.Studienteilnehmer.Rechtsgrundlage

Suchparameter

Folgende Suchparameter sind für das Modul Person relevant, auch in Kombination:

Der Suchparameter "_id" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?_id=103270

Anwendungshinweise: Weitere Informationen zur Suche nach "_id" finden sich in der FHIR-Basisspezifikation - Abschnitt "Parameters for all resources".
Der Suchparameter "_profile" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?_profile=https://www.medizininformatik-initiative.de/fhir/core/modul-person/StructureDefinition/ResearchSubject

Anwendungshinweise: Weitere Informationen zur Suche nach "_profile" finden sich in der FHIR-Basisspezifikation - Abschnitt "Parameters for all resources".
Der Suchparameter "identifier" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?identifier=http://fhir.krankenhaus.example/sid/subjectIdentificationCode|1032702

Anwendungshinweise: Weitere Informationen zur Suche nach "ResearchSubject.identifier" finden sich in der FHIR-Basisspezifikation - Abschnitt "Token Search".
Der Suchparameter "status" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?status=candidate

Anwendungshinweise: Weitere Informationen zur Suche nach "ResearchSubject.status" finden sich in der FHIR-Basisspezifikation - Abschnitt "Token Search".
Der Suchparameter "date" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?date=2022-01-01

Anwendungshinweise: Weitere Informationen zur Suche nach "ResearchSubject.period" finden sich in der FHIR-Basisspezifikation - Abschnitt "Date Search".
Der Suchparameter "study" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?study=ResearchStudy/study

Anwendungshinweise: Weitere Informationen zur Suche nach "ResearchStudy.study" finden sich in der FHIR-Basisspezifikation - Abschnitt "reference".
Der Suchparameter "individual" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?individual=Patient/test

Anwendungshinweise: Weitere Informationen zur Suche nach "ResearchStudy.individual" finden sich in der FHIR-Basisspezifikation - Abschnitt "reference".
Der Suchparameter "consent" MUSS unterstützt werden:

Beispiele:

GET [base]/ResearchSubject?consent=Consent/test

Anwendungshinweise: Weitere Informationen zur Suche nach "ResearchStudy.consent" finden sich in der FHIR-Basisspezifikation - Abschnitt "reference".

Beispiele

Beispiel (vollständig):

{
    "resourceType": "Patient",
    "id": "mii-exa-person-patient-pseudonymisiert",
    "meta": {
        "security":  [
            {
                "code": "HTEST",
                "system": "http://terminology.hl7.org/CodeSystem/v3-ActReason",
                "display": "test health data"
            }
        ],
        "profile":  [
            "https://www.medizininformatik-initiative.de/fhir/core/modul-person/StructureDefinition/PatientPseudonymisiert|2025.0.1"
        ]
    },
    "identifier":  [
        {
            "type": {
                "coding":  [
                    {
                        "code": "PSEUDED",
                        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationValue"
                    }
                ]
            },
            "system": "https://www.medizininformatik-initiative.de/fhir/sid/pseudonym",
            "value": "1234567890"
        }
    ],
    "address":  [
        {
            "type": "both",
            "postalCode": "50",
            "country": "DE"
        }
    ],
    "gender": "male",
    "birthDate": "2000-04-01"
}