The EOM Tumor Marker Test Profile must be submitted for each Estrogen Receptor (ER), Progesterone Receptor (PR), and HER2 Tests for all beneficiaries with an attributed cancer type of Breast Cancer. As indicated in the EOM Tumor Marker Test Profile an Observation.code must be reported leveraging the Tumor Marker Test Value Set. For EOM there are specific LOINC codes permitted for each ER, PR, and HER2 from this value set. The codes accepted for EOM are noted below.

Estrogen Receptor (ER) Test Specified

• 16112-5 Estrogen receptor [Interpretation] in Tissue
• 14130-9 Estrogen receptor [Moles/mass] in Tissue
• 40556-3 Estrogen receptor Ag [Presence] in Tissue by Immune stain
• 85337-4 Estrogen receptor Ag[presence] in Breast cancer specimen by Immune stain
• 85310-1 Estrogen receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain
• 14228-1 Cells.estrogen receptor/100 cells in Tissue by Immune stain
• 85329-1 Cells.estrogen receptor/100 cells in Breast cancer specimen by Immune stain

Progesterone Receptor (PR) Test Specified

• 16113-3 Progesterone receptor [Interpretation] in Tissue
• 10861-3 Progesterone receptor [Mass/mass] in Tissue
• 31207-4 Progesterone receptor [Moles/mass] in Tissue
• 40557-1 Progesterone receptor Ag [Presence] in Tissue by Immune stain
• 85339-0 Progesterone receptor Ag[presence] in Breast cancer specimen by Immune stain
• 85331-7 Progesterone receptor fluorescence intensity [Type] in Breast cancer specimen by Immune stain
• 14230-7 Cells.progesterone receptor/100 cells in Tissue by Immune stain
• 85325-9 Cells.progesterone receptor/100 cells in Breast cancer specimen by Immune stain

HER2 Test Specified

• 32996-1 HER2 [Mass/volume] in Serum
• 48676-1 HER2 [Interpretation] in Tissue
• 72382-5 HER2 [Units/volume] in Tissue by Immunoassay
• 51981-9 HER2 [Presence] in Serum by Immunoassay
• 72383-3 HER2 [Presence] in Tissue by Immunoassay
• 429142 HER2 [Mass/volume] in Serum by Immunoassay
• 85319-2 HER2 [Presence] in Breast cancer specimen by Immune stain
• 74885-5 ERBB2 gene (HER2) duplication associated observations panel - Tissue by FISH
• 74860-8 ERBB2 gene copy number/nucleus in Tissue by FISH
• 49683-6 ERBB2 gene copy number/Chromosome 17 copy number in Tissue by FISH
• 96893-3 ERBB2 gene duplication in Tumor by FISH
• 31150-6 ERBB2 gene duplication [Presence] in Tissue by FISH
• 85318-4 ERBB2 gene duplication [Presence] in Breast cancer specimen by FISH