Dose syntax implementation guidance for FHIR STU3

Trimethoprim, 200mg, oral, twice a day, for 3 days

Product-based instruction using an AMP. Dose expressed per day. Duration of 3 days.

<MedicationRequest xmlns="http://hl7.org/fhir">
    <id value="10169939-6a5b-47ae-b820-524b584eecc8" />
    <contained>
        <Medication>
            <id value="med1" />
            <code>
                <coding>
                    <system value="http://snomed.info/sct" />
                    <code value="28917911000001104" />
                    <display value="Trimethoprim 100mg tablets (Crescent Pharma Ltd)" />
                </coding>
            </code>
        </Medication>
    </contained>
    <status value="active" />
    <intent value="order" />
    <medicationReference>
        <reference value="#med1" />
    </medicationReference>
    <subject>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9999999999" />
        </identifier>
    </subject>
    <dosageInstruction>
        <timing>
            <repeat>
                <boundsDuration>
                    <value value="3" />
                    <unit value="day" />
                    <system value="http://unitsofmeasure.org" />
                    <code value="d" />
                </boundsDuration>
                <frequency value="2" />
                <period value="1" />
                <periodUnit value="d" />
            </repeat>
        </timing>
        <route>
            <coding>
                <system value="http://snomed.info/sct" />
                <code value="26643006" />
                <display value="oral" />
            </coding>
        </route>
        <doseQuantity>
            <value value="2" />
            <unit value="tablet" />
            <system value="http://snomed.info/sct" />
            <code value="428673006" />
        </doseQuantity>
    </dosageInstruction>
</MedicationRequest>

{
    "resourceType": "MedicationRequest",
    "id": "10169939-6a5b-47ae-b820-524b584eecc8",
    "contained":  [
        {
            "resourceType": "Medication",
            "id": "med1",
            "code": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "28917911000001104",
                        "display": "Trimethoprim 100mg tablets (Crescent Pharma Ltd)"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "medicationReference": {
        "reference": "#med1"
    },
    "subject": {
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9999999999"
        }
    },
    "dosageInstruction":  [
        {
            "timing": {
                "repeat": {
                    "boundsDuration": {
                        "value": 3,
                        "unit": "day",
                        "system": "http://unitsofmeasure.org",
                        "code": "d"
                    },
                    "frequency": 2,
                    "period": 1,
                    "periodUnit": "d"
                }
            },
            "route": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "26643006",
                        "display": "oral"
                    }
                ]
            },
            "doseQuantity": {
                "value": 2,
                "unit": "tablet",
                "system": "http://snomed.info/sct",
                "code": "428673006"
            }
        }
    ]
}

MedicationRequest.id[0]	10169939-6a5b-47ae-b820-524b584eecc8
MedicationRequest.contained[0].id[0]	med1
MedicationRequest.contained[0].code[0].coding[0].system[0]	http://snomed.info/sct
MedicationRequest.contained[0].code[0].coding[0].code[0]	28917911000001104
MedicationRequest.contained[0].code[0].coding[0].display[0]	Trimethoprim 100mg tablets (Crescent Pharma Ltd)
MedicationRequest.status[0]	active
MedicationRequest.intent[0]	order
MedicationRequest.medication[0].reference[0]	#med1
MedicationRequest.subject[0].identifier[0].system[0]	https://fhir.nhs.uk/Id/nhs-number
MedicationRequest.subject[0].identifier[0].value[0]	9999999999
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].value[0]	3
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].unit[0]	day
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].system[0]	http://unitsofmeasure.org
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].code[0]	d
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].frequency[0]	2
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].period[0]	1
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].periodUnit[0]	d
MedicationRequest.dosageInstruction[0].route[0].coding[0].system[0]	http://snomed.info/sct
MedicationRequest.dosageInstruction[0].route[0].coding[0].code[0]	26643006
MedicationRequest.dosageInstruction[0].route[0].coding[0].display[0]	oral
MedicationRequest.dosageInstruction[0].dose[0].value[0]	2
MedicationRequest.dosageInstruction[0].dose[0].unit[0]	tablet
MedicationRequest.dosageInstruction[0].dose[0].system[0]	http://snomed.info/sct
MedicationRequest.dosageInstruction[0].dose[0].code[0]	428673006

MedicationRequest

id : 10169939-6a5b-47ae-b820-524b584eecc8

contained

id : med1

code

coding

system : http://snomed.info/sct

code : 28917911000001104

display : Trimethoprim 100mg tablets (Crescent Pharma Ltd)

status : active

intent : order

medication

reference : #med1

subject

identifier

system : https://fhir.nhs.uk/Id/nhs-number

value : 9999999999

dosageInstruction

timing

repeat

bounds

value : 3

unit : day

system : http://unitsofmeasure.org

code : d

frequency : 2

period : 1

periodUnit : d

route

coding

system : http://snomed.info/sct

code : 26643006

display : oral

dose

value : 2

unit : tablet

system : http://snomed.info/sct

code : 428673006

Dose-based instruction using a VTM. Dose expressed per day. Duration of 3 days.

<MedicationRequest xmlns="http://hl7.org/fhir">
    <id value="b65fd46e-4f4e-4676-b135-852ca16f2c91" />
    <contained>
        <Medication>
            <id value="med1" />
            <code>
                <coding>
                    <system value="http://snomed.info/sct" />
                    <code value="32792001" />
                    <display value="Trimethoprim" />
                </coding>
            </code>
        </Medication>
    </contained>
    <status value="active" />
    <intent value="order" />
    <medicationReference>
        <reference value="#med1" />
    </medicationReference>
    <subject>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9999999999" />
        </identifier>
    </subject>
    <dosageInstruction>
        <timing>
            <repeat>
                <boundsDuration>
                    <value value="3" />
                    <unit value="day" />
                    <system value="http://unitsofmeasure.org" />
                    <code value="d" />
                </boundsDuration>
                <frequency value="2" />
                <period value="1" />
                <periodUnit value="d" />
            </repeat>
        </timing>
        <route>
            <coding>
                <system value="http://snomed.info/sct" />
                <code value="26643006" />
                <display value="oral" />
            </coding>
        </route>
        <doseQuantity>
            <value value="200" />
            <unit value="milligram" />
            <system value="http://unitsofmeasure.org" />
            <code value="mg" />
        </doseQuantity>
    </dosageInstruction>
</MedicationRequest>

{
    "resourceType": "MedicationRequest",
    "id": "b65fd46e-4f4e-4676-b135-852ca16f2c91",
    "contained":  [
        {
            "resourceType": "Medication",
            "id": "med1",
            "code": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "32792001",
                        "display": "Trimethoprim"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "medicationReference": {
        "reference": "#med1"
    },
    "subject": {
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9999999999"
        }
    },
    "dosageInstruction":  [
        {
            "timing": {
                "repeat": {
                    "boundsDuration": {
                        "value": 3,
                        "unit": "day",
                        "system": "http://unitsofmeasure.org",
                        "code": "d"
                    },
                    "frequency": 2,
                    "period": 1,
                    "periodUnit": "d"
                }
            },
            "route": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "26643006",
                        "display": "oral"
                    }
                ]
            },
            "doseQuantity": {
                "value": 200,
                "unit": "milligram",
                "system": "http://unitsofmeasure.org",
                "code": "mg"
            }
        }
    ]
}

MedicationRequest.id[0]	b65fd46e-4f4e-4676-b135-852ca16f2c91
MedicationRequest.contained[0].id[0]	med1
MedicationRequest.contained[0].code[0].coding[0].system[0]	http://snomed.info/sct
MedicationRequest.contained[0].code[0].coding[0].code[0]	32792001
MedicationRequest.contained[0].code[0].coding[0].display[0]	Trimethoprim
MedicationRequest.status[0]	active
MedicationRequest.intent[0]	order
MedicationRequest.medication[0].reference[0]	#med1
MedicationRequest.subject[0].identifier[0].system[0]	https://fhir.nhs.uk/Id/nhs-number
MedicationRequest.subject[0].identifier[0].value[0]	9999999999
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].value[0]	3
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].unit[0]	day
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].system[0]	http://unitsofmeasure.org
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].bounds[0].code[0]	d
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].frequency[0]	2
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].period[0]	1
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].periodUnit[0]	d
MedicationRequest.dosageInstruction[0].route[0].coding[0].system[0]	http://snomed.info/sct
MedicationRequest.dosageInstruction[0].route[0].coding[0].code[0]	26643006
MedicationRequest.dosageInstruction[0].route[0].coding[0].display[0]	oral
MedicationRequest.dosageInstruction[0].dose[0].value[0]	200
MedicationRequest.dosageInstruction[0].dose[0].unit[0]	milligram
MedicationRequest.dosageInstruction[0].dose[0].system[0]	http://unitsofmeasure.org
MedicationRequest.dosageInstruction[0].dose[0].code[0]	mg

MedicationRequest

id : b65fd46e-4f4e-4676-b135-852ca16f2c91

contained

id : med1

code

coding

system : http://snomed.info/sct

code : 32792001

display : Trimethoprim

status : active

intent : order

medication

reference : #med1

subject

identifier

system : https://fhir.nhs.uk/Id/nhs-number

value : 9999999999

dosageInstruction

timing

repeat

bounds

value : 3

unit : day

system : http://unitsofmeasure.org

code : d

frequency : 2

period : 1

periodUnit : d

route

coding

system : http://snomed.info/sct

code : 26643006

display : oral

dose

value : 200

unit : milligram

system : http://unitsofmeasure.org

code : mg