Dose syntax implementation guidance for FHIR STU3

This guidance is under active development by NHS Digital and content may be added or updated on a regular basis.

Hydroxocobalamin 10mg/2ml solution for injection ampoules, one to be given by IM injection into the shoulder, 3 times per week for 6 doses, then every 3 months, starting on 1st November 2019

Product-based prescription with course length as number of doses, sequential dosing.
<MedicationRequest xmlns="http://hl7.org/fhir">
    <id value="6062d3bb-f6cf-41ec-aa71-dcd42299b10f" />
    <contained>
        <Medication>
            <id value="med1" />
            <code>
                <coding>
                    <system value="http://snomed.info/sct" />
                    <code value="24856311000001103" />
                    <display value="Hydroxocobalamin 10mg/2ml solution for injection ampoules" />
                </coding>
            </code>
        </Medication>
    </contained>
    <status value="active" />
    <intent value="order" />
    <medicationReference>
        <reference value="#med1" />
    </medicationReference>
    <subject>
        <identifier>
            <system value="https://fhir.nhs.uk/Id/nhs-number" />
            <value value="9999999999" />
        </identifier>
    </subject>
    <dosageInstruction>
        <sequence value="1" />
        <timing>
            <repeat>
                <count value="6" />
                <frequency value="3" />
                <period value="1" />
                <periodUnit value="wk" />
            </repeat>
        </timing>
        <site>
            <coding>
                <system value="http://snomed.info/sct" />
                <code value="16982005" />
                <display value="Shoulder" />
            </coding>
        </site>
        <route>
            <coding>
                <system value="http://snomed.info/sct" />
                <code value="78421000" />
                <display value="intramuscular route" />
            </coding>
        </route>
        <doseQuantity>
            <value value="1" />
            <unit value="ampoule" />
            <system value="http://snomed.info/sct" />
            <code value="413516001" />
        </doseQuantity>
    </dosageInstruction>
    <dosageInstruction>
        <sequence value="2" />
        <timing>
            <repeat>
                <boundsPeriod>
                    <start value="2019-11-01" />
                </boundsPeriod>
                <frequency value="1" />
                <period value="3" />
                <periodUnit value="mo" />
            </repeat>
        </timing>
        <site>
            <coding>
                <system value="http://snomed.info/sct" />
                <code value="16982005" />
                <display value="Shoulder" />
            </coding>
        </site>
        <route>
            <coding>
                <system value="http://snomed.info/sct" />
                <code value="78421000" />
                <display value="intramuscular route" />
            </coding>
        </route>
        <doseQuantity>
            <value value="1" />
            <unit value="ampoule" />
            <system value="http://snomed.info/sct" />
            <code value="413516001" />
        </doseQuantity>
    </dosageInstruction>
</MedicationRequest>
{
    "resourceType": "MedicationRequest",
    "id": "6062d3bb-f6cf-41ec-aa71-dcd42299b10f",
    "contained":  [
        {
            "resourceType": "Medication",
            "id": "med1",
            "code": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "24856311000001103",
                        "display": "Hydroxocobalamin 10mg/2ml solution for injection ampoules"
                    }
                ]
            }
        }
    ],
    "status": "active",
    "intent": "order",
    "medicationReference": {
        "reference": "#med1"
    },
    "subject": {
        "identifier": {
            "system": "https://fhir.nhs.uk/Id/nhs-number",
            "value": "9999999999"
        }
    },
    "dosageInstruction":  [
        {
            "sequence": 1,
            "timing": {
                "repeat": {
                    "count": 6,
                    "frequency": 3,
                    "period": 1,
                    "periodUnit": "wk"
                }
            },
            "site": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "16982005",
                        "display": "Shoulder"
                    }
                ]
            },
            "route": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "78421000",
                        "display": "intramuscular route"
                    }
                ]
            },
            "doseQuantity": {
                "value": 1,
                "unit": "ampoule",
                "system": "http://snomed.info/sct",
                "code": "413516001"
            }
        },
        {
            "sequence": 2,
            "timing": {
                "repeat": {
                    "boundsPeriod": {
                        "start": "2019-11-01"
                    },
                    "frequency": 1,
                    "period": 3,
                    "periodUnit": "mo"
                }
            },
            "site": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "16982005",
                        "display": "Shoulder"
                    }
                ]
            },
            "route": {
                "coding":  [
                    {
                        "system": "http://snomed.info/sct",
                        "code": "78421000",
                        "display": "intramuscular route"
                    }
                ]
            },
            "doseQuantity": {
                "value": 1,
                "unit": "ampoule",
                "system": "http://snomed.info/sct",
                "code": "413516001"
            }
        }
    ]
}
MedicationRequest.id[0]6062d3bb-f6cf-41ec-aa71-dcd42299b10f
MedicationRequest.contained[0].id[0]med1
MedicationRequest.contained[0].code[0].coding[0].system[0]http://snomed.info/sct
MedicationRequest.contained[0].code[0].coding[0].code[0]24856311000001103
MedicationRequest.contained[0].code[0].coding[0].display[0]Hydroxocobalamin 10mg/2ml solution for injection ampoules
MedicationRequest.status[0]active
MedicationRequest.intent[0]order
MedicationRequest.medication[0].reference[0]#med1
MedicationRequest.subject[0].identifier[0].system[0]https://fhir.nhs.uk/Id/nhs-number
MedicationRequest.subject[0].identifier[0].value[0]9999999999
MedicationRequest.dosageInstruction[0].sequence[0]1
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].count[0]6
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].frequency[0]3
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].period[0]1
MedicationRequest.dosageInstruction[0].timing[0].repeat[0].periodUnit[0]wk
MedicationRequest.dosageInstruction[0].site[0].coding[0].system[0]http://snomed.info/sct
MedicationRequest.dosageInstruction[0].site[0].coding[0].code[0]16982005
MedicationRequest.dosageInstruction[0].site[0].coding[0].display[0]Shoulder
MedicationRequest.dosageInstruction[0].route[0].coding[0].system[0]http://snomed.info/sct
MedicationRequest.dosageInstruction[0].route[0].coding[0].code[0]78421000
MedicationRequest.dosageInstruction[0].route[0].coding[0].display[0]intramuscular route
MedicationRequest.dosageInstruction[0].dose[0].value[0]1
MedicationRequest.dosageInstruction[0].dose[0].unit[0]ampoule
MedicationRequest.dosageInstruction[0].dose[0].system[0]http://snomed.info/sct
MedicationRequest.dosageInstruction[0].dose[0].code[0]413516001
MedicationRequest.dosageInstruction[1].sequence[0]2
MedicationRequest.dosageInstruction[1].timing[0].repeat[0].bounds[0].start[0]2019-11-01
MedicationRequest.dosageInstruction[1].timing[0].repeat[0].frequency[0]1
MedicationRequest.dosageInstruction[1].timing[0].repeat[0].period[0]3
MedicationRequest.dosageInstruction[1].timing[0].repeat[0].periodUnit[0]mo
MedicationRequest.dosageInstruction[1].site[0].coding[0].system[0]http://snomed.info/sct
MedicationRequest.dosageInstruction[1].site[0].coding[0].code[0]16982005
MedicationRequest.dosageInstruction[1].site[0].coding[0].display[0]Shoulder
MedicationRequest.dosageInstruction[1].route[0].coding[0].system[0]http://snomed.info/sct
MedicationRequest.dosageInstruction[1].route[0].coding[0].code[0]78421000
MedicationRequest.dosageInstruction[1].route[0].coding[0].display[0]intramuscular route
MedicationRequest.dosageInstruction[1].dose[0].value[0]1
MedicationRequest.dosageInstruction[1].dose[0].unit[0]ampoule
MedicationRequest.dosageInstruction[1].dose[0].system[0]http://snomed.info/sct
MedicationRequest.dosageInstruction[1].dose[0].code[0]413516001
MedicationRequest

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