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<StructureDefinition xmlns="http://hl7.org/fhir">
  <meta>
    <lastUpdated value="2017-09-30T17:43:26.58+08:00" />
  </meta>
  <url value="StructureDefinition/Obs-DiscreteVariant_Differentials" />
  <name value="Obs-DiscreteVariant_Differentials" />
  <status value="draft" />
  <date value="2017-09-28T10:23:34.177+08:00" />
  <fhirVersion value="3.0.1" />
  <kind value="resource" />
  <abstract value="false" />
  <type value="Observation" />
  <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Observation" />
  <derivation value="constraint" />
  <differential>
    <element id="Observation.component">
      <path value="Observation.component" />
      <slicing>
        <description value="  " />
        <rules value="open" />
      </slicing>
    </element>
    <element id="Observation.component:Component">
      <path value="Observation.component" />
      <sliceName value="Component" />
      <max value="1" />
    </element>
    <element id="Observation.component:Component.code.coding">
      <path value="Observation.component.code.coding" />
      <slicing>
        <description value="&quot;DNA sequence variant ID :&#xA;Identifier for DNA sequence variant. If a germline variant, ClinVar or dbSNP identifier should be used. If a somatic variant, COSMIC identifier should be used, unless in ClinVar then either maybe used. Need to provide the code system used (ClinVar, dbSNP, COSMIC) LONIC Code: (48003-8 ).&quot;&#xD;&#xA;" />
        <rules value="open" />
      </slicing>
      <max value="1" />
      <fixedCoding>
        <system value="http://loinc.org" />
        <code value="48003-8" />
        <display value="DNAVariantID" />
      </fixedCoding>
    </element>
    <element id="Observation.component:Component.value[x]:valueCodeableConcept">
      <path value="Observation.component.valueCodeableConcept" />
      <sliceName value="valueCodeableConcept" />
      <type>
        <code value="CodeableConcept" />
      </type>
    </element>
    <element id="Observation.component:Component.value[x]:valueCodeableConcept.coding">
      <path value="Observation.component.valueCodeableConcept.coding" />
      <slicing>
        <description value=" " />
        <rules value="open" />
      </slicing>
      <fixedCoding>
        <system value="http://www.ncbi.nlm.nih.gov/clinvar" />
        <code value="51975-1  " />
      </fixedCoding>
    </element>
    <element id="Observation.component:Component">
      <path value="Observation.component" />
      <sliceName value="Component" />
      <max value="1" />
    </element>
    <element id="Observation.component:Component.code.coding">
      <path value="Observation.component.code.coding" />
      <slicing>
        <description value=" " />
        <rules value="open" />
      </slicing>
      <max value="1" />
      <fixedCoding>
        <system value="http://loinc.org" />
        <code value="48004-6" />
        <display value="DNAChangeName" />
      </fixedCoding>
    </element>
    <element id="Observation.component:Component.value[x]:valueCodeableConcept">
      <path value="Observation.component.valueCodeableConcept" />
      <sliceName value="valueCodeableConcept" />
      <type>
        <code value="CodeableConcept" />
      </type>
    </element>
    <element id="Observation.component:Component.value[x]:valueCodeableConcept.coding">
      <path value="Observation.component.valueCodeableConcept.coding" />
      <slicing>
        <description value=" " />
        <rules value="open" />
      </slicing>
      <fixedCoding>
        <system value="http://www.hgvs.org/mutnomen" />
        <code value="c.1249C&gt;T" />
        <display value="c.1249C&gt;T" />
      </fixedCoding>
    </element>
    <element id="Observation.component:Component">
      <path value="Observation.component" />
      <sliceName value="Component" />
      <max value="1" />
    </element>
    <element id="Observation.component:Component.code.coding">
      <path value="Observation.component.code.coding" />
      <slicing>
        <description value="&quot;DNA sequence variant type :&#xA;Codified type for associated DNA sequence variant. DNA sequence variants use the HGVS notation, which implies the DNA sequence variant type. LONIC Code: (48019-4 ).&quot;&#xD;&#xA;" />
        <rules value="open" />
      </slicing>
      <max value="1" />
      <fixedCoding>
        <system value="http://loinc.org" />
        <code value="48019-4" />
        <display value="DNAchangetype" />
      </fixedCoding>
    </element>
    <element id="Observation.component:Component.value[x]:valueCodeableConcept">
      <path value="Observation.component.valueCodeableConcept" />
      <sliceName value="valueCodeableConcept" />
      <type>
        <code value="CodeableConcept" />
      </type>
    </element>
    <element id="valueCodeableConcept:valueCodeableConcept.coding">
      <path value="Observation.component.valueCodeableConcept.coding" />
      <slicing>
        <description value=" " />
        <rules value="open" />
      </slicing>
      <fixedCoding>
        <system value="http://loinc.org" />
        <code value="LA6690-7" />
        <display value="Substitution" />
      </fixedCoding>
    </element>
  </differential>
</StructureDefinition>

name : Obs-DiscreteVariant_Differentials

{

}

<name value="Obs-DiscreteVariant_Differentials" />