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{
 "resourceType": "StructureDefinition",
 "id": "EffectEvidenceSynthesis",
 "meta": {
 "lastUpdated": "2018-12-27T11:37:54.724+00:00"
 },
 "text": {
 "status": "generated",
 "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"formats.html#table\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"formats.html#table\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"formats.html#table\" title=\"Minimum and Maximum # of times the the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"formats.html#table\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"formats.html#table\" title=\"Additional information about the element\">Description &amp; Constraints</a><a href=\"formats.html#table\" title=\"Legend for this format\"><img src=\"help16.png\" alt=\"doco\" style=\"background-color: inherit\" /></a></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Resource\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis : The EffectEvidenceSynthesis resource describes the difference in an outcome between exposures states in a population where the effect estimate is derived from a combination of research studies.\">EffectEvidenceSynthesis<a name=\"EffectEvidenceSynthesis\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"conformance-rules.html#constraints\" title=\"This element has or is affected by some invariants\">I</a><a style=\"padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold; color: black; background-color: #fff5e6\" href=\"versions.html#std-process\" title=\"Standards Status = Trial Use\">TU</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"domainresource.html\">DomainResource</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A quantified estimate of effect based on a body of evidence\r\n + Warning: Name should be usable as an identifier for the module by machine processing applications such as code generation Elements defined in Ancestors: \r\n <a href=\"resource.html#Resource\" title=\"The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.\">id</a>, \r\n <a href=\"resource.html#Resource\" title=\"The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.\">meta</a>, \r\n <a href=\"resource.html#Resource\" title=\"A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.\">implicitRules</a>, \r\n <a href=\"resource.html#Resource\" title=\"The base language in which the resource is written.\">language</a>, \r\n <a href=\"domainresource.html#DomainResource\" title=\"A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.\">text</a>, \r\n <a href=\"domainresource.html#DomainResource\" title=\"These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.\">contained</a>, \r\n <a href=\"domainresource.html#DomainResource\" title=\"May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.\">extension</a>, \r\n <a href=\"domainresource.html#DomainResource\" title=\"May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.&#xA;&#xA;Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).\">modifierExtension</a></td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.url : An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.\">url<a name=\"EffectEvidenceSynthesis.url\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique)</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.identifier : A formal identifier that is used to identify this effect evidence synthesis when it is represented in other formats, or referenced in a specification, model, design or an instance.\">identifier<a name=\"EffectEvidenceSynthesis.identifier\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#Identifier\">Identifier</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Additional identifier for the effect evidence synthesis\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.version : The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.\">version<a name=\"EffectEvidenceSynthesis.version\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Business version of the effect evidence synthesis</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.name : A natural language name identifying the effect evidence synthesis. This name should be usable as an identifier for the module by machine processing applications such as code generation.\">name<a name=\"EffectEvidenceSynthesis.name\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"conformance-rules.html#constraints\" title=\"This element has or is affected by some invariants\">I</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Name for this effect evidence synthesis (computer friendly)</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />title<a name=\"EffectEvidenceSynthesis.title\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Name for this effect evidence synthesis (human friendly)</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />status<a name=\"EffectEvidenceSynthesis.status\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"conformance-rules.html#isModifier\" title=\"This element is a modifier element\">?!</a><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">draft | active | retired | unknown\r\n <a href=\"valueset-publication-status.html\" title=\"The lifecycle status of an artifact.\">PublicationStatus</a> (\r\n <a href=\"terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">Required</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.date : The date (and optionally time) when the effect evidence synthesis was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the effect evidence synthesis changes.\">date<a name=\"EffectEvidenceSynthesis.date\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#dateTime\">dateTime</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Date last changed</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />publisher<a name=\"EffectEvidenceSynthesis.publisher\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Name of the publisher (organization or individual)</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />contact<a name=\"EffectEvidenceSynthesis.contact\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#ContactDetail\">ContactDetail</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Contact details for the publisher\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />description<a name=\"EffectEvidenceSynthesis.description\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#markdown\">markdown</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Natural language description of the effect evidence synthesis</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQkad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRPz58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPvszv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866OUPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6if3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hYwbdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iSFVResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />note<a name=\"EffectEvidenceSynthesis.note\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#Annotation\">Annotation</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Used for footnotes or explanatory notes\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.useContext : The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.\">useContext<a name=\"EffectEvidenceSynthesis.useContext\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#UsageContext\">UsageContext</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The context that the content is intended to support\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />jurisdiction<a name=\"EffectEvidenceSynthesis.jurisdiction\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Intended jurisdiction for effect evidence synthesis (if applicable)\r\n <a href=\"valueset-jurisdiction.html\" title=\"Countries and regions within which this artifact is targeted for use.\">Jurisdiction</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.copyright : A copyright statement relating to the effect evidence synthesis and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the effect evidence synthesis.\">copyright<a name=\"EffectEvidenceSynthesis.copyright\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#markdown\">markdown</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Use and/or publishing restrictions</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />approvalDate<a name=\"EffectEvidenceSynthesis.approvalDate\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#date\">date</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">When the effect evidence synthesis was approved by publisher</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />lastReviewDate<a name=\"EffectEvidenceSynthesis.lastReviewDate\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#date\">date</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">When the effect evidence synthesis was last reviewed</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />effectivePeriod<a name=\"EffectEvidenceSynthesis.effectivePeriod\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#Period\">Period</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">When the effect evidence synthesis is expected to be used</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" /><span title=\"EffectEvidenceSynthesis.topic : Descriptive topics related to the content of the EffectEvidenceSynthesis. Topics provide a high-level categorization grouping types of EffectEvidenceSynthesiss that can be useful for filtering and searching.\">topic<a name=\"EffectEvidenceSynthesis.topic\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc.\r\n <a href=\"valueset-definition-topic.html\" title=\"High-level categorization of the definition, used for searching, sorting, and filtering.\">DefinitionTopic</a> (\r\n <a href=\"terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\">Example</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />author<a name=\"EffectEvidenceSynthesis.author\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#ContactDetail\">ContactDetail</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Who authored the content\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />editor<a name=\"EffectEvidenceSynthesis.editor\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#ContactDetail\">ContactDetail</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Who edited the content\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />reviewer<a name=\"EffectEvidenceSynthesis.reviewer\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#ContactDetail\">ContactDetail</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Who reviewed the content\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />endorser<a name=\"EffectEvidenceSynthesis.endorser\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#ContactDetail\">ContactDetail</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Who endorsed the content\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />relatedArtifact<a name=\"EffectEvidenceSynthesis.relatedArtifact\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"metadatatypes.html#RelatedArtifact\">RelatedArtifact</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Additional documentation, citations, etc.\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />synthesisType<a name=\"EffectEvidenceSynthesis.synthesisType\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type of synthesis\r\n <a href=\"valueset-synthesis-type.html\" title=\"Types of combining results from a body of evidence (eg. summary data meta-analysis).\">SynthesisType</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />studyType<a name=\"EffectEvidenceSynthesis.studyType\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type of study\r\n <a href=\"valueset-study-type.html\" title=\"Types of research studies (types of research methods).\">StudyType</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\" />population<a name=\"EffectEvidenceSynthesis.population\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"references.html#Reference\">Reference</a>(\r\n <a href=\"evidencevariable.html\">EvidenceVariable</a>)\r\n </td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What population?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\" />exposure<a name=\"EffectEvidenceSynthesis.exposure\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"references.html#Reference\">Reference</a>(\r\n <a href=\"evidencevariable.html\">EvidenceVariable</a>)\r\n </td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What exposure?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\" />exposureAlternative<a name=\"EffectEvidenceSynthesis.exposureAlternative\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"references.html#Reference\">Reference</a>(\r\n <a href=\"evidencevariable.html\">EvidenceVariable</a>)\r\n </td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What comparison exposure?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\" />outcome<a name=\"EffectEvidenceSynthesis.outcome\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"references.html#Reference\">Reference</a>(\r\n <a href=\"evidencevariable.html\">EvidenceVariable</a>)\r\n </td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What outcome?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\" />sampleSize<a name=\"EffectEvidenceSynthesis.sampleSize\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"backboneelement.html\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What sample size was involved?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />description<a name=\"EffectEvidenceSynthesis.sampleSize.description\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Description of sample size</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />numberOfStudies<a name=\"EffectEvidenceSynthesis.sampleSize.numberOfStudies\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">How many studies?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />numberOfParticipants<a name=\"EffectEvidenceSynthesis.sampleSize.numberOfParticipants\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">How many participants?</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\" />resultsByExposure<a name=\"EffectEvidenceSynthesis.resultsByExposure\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"backboneelement.html\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What was the result per exposure?\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />description<a name=\"EffectEvidenceSynthesis.resultsByExposure.description\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Description of results by exposure</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />exposureState<a name=\"EffectEvidenceSynthesis.resultsByExposure.exposureState\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">exposure | exposure-alternative\r\n <a href=\"valueset-exposure-state.html\" title=\"Whether the results by exposure is describing the results for the primary exposure of interest (exposure) or the alternative state (exposureAlternative).\">ExposureState</a> (\r\n <a href=\"terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">Required</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />variantState<a name=\"EffectEvidenceSynthesis.resultsByExposure.variantState\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant exposure states\r\n <a href=\"valueset-evidence-variant-state.html\" title=\"Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.\">EvidenceVariantState</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\" />riskEvidenceSynthesis<a name=\"EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"references.html#Reference\">Reference</a>(\r\n <a href=\"riskevidencesynthesis.html\">RiskEvidenceSynthesis</a>)\r\n </td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Risk evidence synthesis</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\" />effectEstimate<a name=\"EffectEvidenceSynthesis.effectEstimate\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">Σ</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"backboneelement.html\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What was the estimated effect\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />description<a name=\"EffectEvidenceSynthesis.effectEstimate.description\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Description of effect estimate</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />type<a name=\"EffectEvidenceSynthesis.effectEstimate.type\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type of efffect estimate\r\n <a href=\"valueset-effect-estimate-type.html\" title=\"Whether the effect estimate is an absolute effect estimate (absolute difference) or a relative effect estimate (relative difference), and the specific type of effect estimate (eg relative risk or median difference).\">EffectEstimateType</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />variantState<a name=\"EffectEvidenceSynthesis.effectEstimate.variantState\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant exposure states\r\n <a href=\"valueset-evidence-variant-state.html\" title=\"Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.\">EvidenceVariantState</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />value<a name=\"EffectEvidenceSynthesis.effectEstimate.value\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#decimal\">decimal</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Point estimate</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />unitOfMeasure<a name=\"EffectEvidenceSynthesis.effectEstimate.unitOfMeasure\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What unit is the outcome described in?\r\n <a href=\"valueset-ucum-units.html\" title=\"Unified Code for Units of Measure (UCUM).\">UCUM Codes</a> (\r\n <a href=\"terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">Required</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\" />precisionEstimate<a name=\"EffectEvidenceSynthesis.effectEstimate.precisionEstimate\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"backboneelement.html\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">How precise the estimate is\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAANElEQVR42u3WwQkAIAwDwO6a/WdQVygW/VzhniGQVytJdZxb3cyk3/0AAMDFP28EAADglQ1WK0BWTK0BuwAAAABJRU5ErkJggg==)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />type<a name=\"EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type of precision estimate\r\n <a href=\"valueset-precision-estimate-type.html\" title=\"Method of reporting variability of estimates, such as confidence intervals, interquartile range or standard deviation.\">PrecisionEstimateType</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAANElEQVR42u3WwQkAIAwDwO6a/WdQVygW/VzhniGQVytJdZxb3cyk3/0AAMDFP28EAADglQ1WK0BWTK0BuwAAAABJRU5ErkJggg==)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />level<a name=\"EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#decimal\">decimal</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Level of confidence interval</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAANElEQVR42u3WwQkAIAwDwO6a/WdQVygW/VzhniGQVytJdZxb3cyk3/0AAMDFP28EAADglQ1WK0BWTK0BuwAAAABJRU5ErkJggg==)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />from<a name=\"EffectEvidenceSynthesis.effectEstimate.precisionEstimate.from\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#decimal\">decimal</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Lower bound</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\" />to<a name=\"EffectEvidenceSynthesis.effectEstimate.precisionEstimate.to\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#decimal\">decimal</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Upper bound</td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\" />certainty<a name=\"EffectEvidenceSynthesis.certainty\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"backboneelement.html\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">How certain is the effect\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR42u3QwQkAMAwDsezq/WdIO4XJQwa9DTdJpulv258AAMANIgAAADUPYAVAgAJ//usAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />rating<a name=\"EffectEvidenceSynthesis.certainty.rating\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Certainty rating\r\n <a href=\"valueset-evidence-quality.html\" title=\"The quality of the evidence described. The code system used specifies the quality scale used to grade this evidence source while the code specifies the actual quality score (represented as a coded value) associated with the evidence.\">QualityOfEvidenceRating</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR42u3QwQkAMAwDsezq/WdIO4XJQwa9DTdJpulv258AAMANIgAAADUPYAVAgAJ//usAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />note<a name=\"EffectEvidenceSynthesis.certainty.note\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#Annotation\">Annotation</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Used for footnotes or explanatory notes\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\" />certaintySubcomponent<a name=\"EffectEvidenceSynthesis.certainty.certaintySubcomponent\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"backboneelement.html\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A component that contributes to the overall certainty\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3WsQkAQAgDQHfN/jO8Fs7wIFzg+pAqlaQumbxrnQEAgP3zRgAAAH5paoVAgEFM+GgAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />type<a name=\"EffectEvidenceSynthesis.certainty.certaintySubcomponent.type\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type of subcomponent of certainty rating\r\n <a href=\"valueset-certainty-subcomponent-type.html\" title=\"The subcomponent classification of quality of evidence rating systems.\">CertaintySubcomponentType</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3WsQkAQAgDQHfN/jO8Fs7wIFzg+pAqlaQumbxrnQEAgP3zRgAAAH5paoVAgEFM+GgAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />rating<a name=\"EffectEvidenceSynthesis.certainty.certaintySubcomponent.rating\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Subcomponent certainty rating\r\n <a href=\"valueset-certainty-subcomponent-rating.html\" title=\"The quality rating of the subcomponent of a quality of evidence rating.\">CertaintySubcomponentRating</a> (\r\n <a href=\"terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">Extensible</a>)\r\n </td></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3WQQkAMAwDwHqNfw1rVZRBL3ACklcqSV0yedc6AwDAN3/cCAAAwJYGdQVAgLmrCkUAAAAASUVORK5CYII=)\" class=\"hierarchy\"><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\" /><img src=\"data: image/png;base64,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\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\" />note<a name=\"EffectEvidenceSynthesis.certainty.certaintySubcomponent.note\"></a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\" /><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"datatypes.html#Annotation\">Annotation</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Used for footnotes or explanatory notes\r\n </td></tr><tr><td colspan=\"5\" class=\"hierarchy\"> <a href=\"formats.html#table\" title=\"Legend for this format\"><img src=\"help16.png\" alt=\"doco\" style=\"background-color: inherit\" /> Documentation for this format\r\n </a></td></tr></table></div>"
 },
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-category",
 "valueString": "Specialized.Evidence-Based Medicine"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
 "valueCode": "trial-use"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
 "valueInteger": 0
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category",
 "valueCode": "business"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
 "valueCode": "cds"
 }
 ],
 "url": "http://hl7.org/fhir/StructureDefinition/EffectEvidenceSynthesis",
 "version": "4.0.0",
 "name": "EffectEvidenceSynthesis",
 "status": "draft",
 "date": "2018-12-27T11:37:54+00:00",
 "publisher": "Health Level Seven International (Clinical Decision Support)",
 "contact": [
 {
 "telecom": [
 {
 "system": "url",
 "value": "http://hl7.org/fhir"
 }
 ]
 },
 {
 "telecom": [
 {
 "system": "url",
 "value": "http://www.hl7.org/Special/committees/dss/index.cfm"
 }
 ]
 }
 ],
 "description": "The EffectEvidenceSynthesis resource describes the difference in an outcome between exposures states in a population where the effect estimate is derived from a combination of research studies.",
 "fhirVersion": "4.0.0",
 "mapping": [
 {
 "identity": "workflow",
 "uri": "http://hl7.org/fhir/workflow",
 "name": "Workflow Pattern"
 },
 {
 "identity": "w5",
 "uri": "http://hl7.org/fhir/fivews",
 "name": "FiveWs Pattern Mapping"
 },
 {
 "identity": "objimpl",
 "uri": "http://hl7.org/fhir/object-implementation",
 "name": "Object Implementation Information"
 },
 {
 "identity": "rim",
 "uri": "http://hl7.org/v3",
 "name": "RIM Mapping"
 }
 ],
 "kind": "resource",
 "abstract": false,
 "type": "EffectEvidenceSynthesis",
 "baseDefinition": "http://hl7.org/fhir/StructureDefinition/DomainResource",
 "_baseDefinition": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-codegen-super",
 "valueString": "MetadataResource"
 }
 ]
 },
 "derivation": "specialization",
 "snapshot": {
 "element": [
 {
 "id": "EffectEvidenceSynthesis",
 "path": "EffectEvidenceSynthesis",
 "short": "A quantified estimate of effect based on a body of evidence",
 "definition": "The EffectEvidenceSynthesis resource describes the difference in an outcome between exposures states in a population where the effect estimate is derived from a combination of research studies.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis",
 "min": 0,
 "max": "*"
 },
 "constraint": [
 {
 "key": "dom-2",
 "severity": "error",
 "human": "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
 "expression": "contained.contained.empty()",
 "xpath": "not(parent::f:contained and f:contained)",
 "source": "DomainResource"
 },
 {
 "key": "dom-4",
 "severity": "error",
 "human": "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
 "expression": "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
 "xpath": "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
 "source": "DomainResource"
 },
 {
 "key": "dom-3",
 "severity": "error",
 "human": "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
 "expression": "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
 "xpath": "not(exists(for $contained in f:contained return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
 "source": "DomainResource"
 },
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
 "valueBoolean": true
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
 "valueMarkdown": "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
 }
 ],
 "key": "dom-6",
 "severity": "warning",
 "human": "A resource should have narrative for robust management",
 "expression": "text.div.exists()",
 "xpath": "exists(f:text/h:div)",
 "source": "DomainResource"
 },
 {
 "key": "dom-5",
 "severity": "error",
 "human": "If a resource is contained in another resource, it SHALL NOT have a security label",
 "expression": "contained.meta.security.empty()",
 "xpath": "not(exists(f:contained/*/f:meta/f:security))",
 "source": "DomainResource"
 },
 {
 "key": "ees-0",
 "severity": "warning",
 "human": "Name should be usable as an identifier for the module by machine processing applications such as code generation",
 "expression": "name.matches('[A-Z]([A-Za-z0-9_]){0,254}')",
 "xpath": "not(exists(f:name/@value)) or matches(f:name/@value, '[A-Z]([A-Za-z0-9_]){0,254}')"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "Entity. Role, or Act"
 },
 {
 "identity": "workflow",
 "map": "Definition"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.id",
 "path": "EffectEvidenceSynthesis.id",
 "short": "Logical id of this artifact",
 "definition": "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
 "comment": "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Resource.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "id"
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.meta",
 "path": "EffectEvidenceSynthesis.meta",
 "short": "Metadata about the resource",
 "definition": "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Resource.meta",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Meta"
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.implicitRules",
 "path": "EffectEvidenceSynthesis.implicitRules",
 "short": "A set of rules under which this content was created",
 "definition": "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
 "comment": "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Resource.implicitRules",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "uri"
 }
 ],
 "isModifier": true,
 "isModifierReason": "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.language",
 "path": "EffectEvidenceSynthesis.language",
 "short": "Language of the resource content",
 "definition": "The base language in which the resource is written.",
 "comment": "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Resource.language",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "code"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
 "valueCanonical": "http://hl7.org/fhir/ValueSet/all-languages"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "Language"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
 "valueBoolean": true
 }
 ],
 "strength": "preferred",
 "description": "A human language.",
 "valueSet": "http://hl7.org/fhir/ValueSet/languages"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.text",
 "path": "EffectEvidenceSynthesis.text",
 "short": "Text summary of the resource, for human interpretation",
 "definition": "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
 "comment": "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
 "alias": [
 "narrative",
 "html",
 "xhtml",
 "display"
 ],
 "min": 0,
 "max": "1",
 "base": {
 "path": "DomainResource.text",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Narrative"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "Act.text?"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.contained",
 "path": "EffectEvidenceSynthesis.contained",
 "short": "Contained, inline Resources",
 "definition": "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
 "comment": "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
 "alias": [
 "inline resources",
 "anonymous resources",
 "contained resources"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "DomainResource.contained",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Resource"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.extension",
 "path": "EffectEvidenceSynthesis.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "DomainResource.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.modifierExtension",
 "path": "EffectEvidenceSynthesis.modifierExtension",
 "short": "Extensions that cannot be ignored",
 "definition": "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "DomainResource.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.url",
 "path": "EffectEvidenceSynthesis.url",
 "short": "Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique)",
 "definition": "An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.",
 "comment": "Can be a urn:uuid: or a urn:oid: but real http: addresses are preferred. Multiple instances may share the same URL if they have a distinct version.\n\nThe determination of when to create a new version of a resource (same url, new version) vs. defining a new artifact is up to the author. Considerations for making this decision are found in [Technical and Business Versions](resource.html#versions). \n\nIn some cases, the resource can no longer be found at the stated url, but the url itself cannot change. Implementations can use the [meta.source](resource.html#meta) element to indicate where the current master source of the resource can be found.",
 "requirements": "Allows the effect evidence synthesis to be referenced by a single globally unique identifier.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.url",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "uri"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.url"
 },
 {
 "identity": "w5",
 "map": "FiveWs.identifier"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.identifier",
 "path": "EffectEvidenceSynthesis.identifier",
 "short": "Additional identifier for the effect evidence synthesis",
 "definition": "A formal identifier that is used to identify this effect evidence synthesis when it is represented in other formats, or referenced in a specification, model, design or an instance.",
 "comment": "Typically, this is used for identifiers that can go in an HL7 V3 II (instance identifier) data type, and can then identify this effect evidence synthesis outside of FHIR, where it is not possible to use the logical URI.",
 "requirements": "Allows externally provided and/or usable business identifiers to be easily associated with the module.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.identifier",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Identifier"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.identifier"
 },
 {
 "identity": "w5",
 "map": "FiveWs.identifier"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.version",
 "path": "EffectEvidenceSynthesis.version",
 "short": "Business version of the effect evidence synthesis",
 "definition": "The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.",
 "comment": "There may be different effect evidence synthesis instances that have the same identifier but different versions. The version can be appended to the url in a reference to allow a reference to a particular business version of the effect evidence synthesis with the format [url]|[version].",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.version",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.version"
 },
 {
 "identity": "w5",
 "map": "FiveWs.version"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.name",
 "path": "EffectEvidenceSynthesis.name",
 "short": "Name for this effect evidence synthesis (computer friendly)",
 "definition": "A natural language name identifying the effect evidence synthesis. This name should be usable as an identifier for the module by machine processing applications such as code generation.",
 "comment": "The name is not expected to be globally unique. The name should be a simple alphanumeric type name to ensure that it is machine-processing friendly.",
 "requirements": "Support human navigation and code generation.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.name",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "condition": [
 "inv-0"
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.title",
 "path": "EffectEvidenceSynthesis.title",
 "short": "Name for this effect evidence synthesis (human friendly)",
 "definition": "A short, descriptive, user-friendly title for the effect evidence synthesis.",
 "comment": "This name does not need to be machine-processing friendly and may contain punctuation, white-space, etc.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.title",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.title"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.status",
 "path": "EffectEvidenceSynthesis.status",
 "short": "draft | active | retired | unknown",
 "definition": "The status of this effect evidence synthesis. Enables tracking the life-cycle of the content.",
 "comment": "Allows filtering of effect evidence synthesiss that are appropriate for use versus not.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.status",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "code": "code"
 }
 ],
 "isModifier": true,
 "isModifierReason": "This is labeled as \"Is Modifier\" because applications should not use a retired {{title}} without due consideration",
 "isSummary": true,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "PublicationStatus"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
 "valueBoolean": true
 }
 ],
 "strength": "required",
 "description": "The lifecycle status of an artifact.",
 "valueSet": "http://hl7.org/fhir/ValueSet/publication-status|4.0.0"
 },
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.status"
 },
 {
 "identity": "w5",
 "map": "FiveWs.status"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.date",
 "path": "EffectEvidenceSynthesis.date",
 "short": "Date last changed",
 "definition": "The date (and optionally time) when the effect evidence synthesis was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the effect evidence synthesis changes.",
 "comment": "Note that this is not the same as the resource last-modified-date, since the resource may be a secondary representation of the effect evidence synthesis. Additional specific dates may be added as extensions or be found by consulting Provenances associated with past versions of the resource.",
 "alias": [
 "Revision Date"
 ],
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.date",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "dateTime"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.date"
 },
 {
 "identity": "w5",
 "map": "FiveWs.recorded"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.publisher",
 "path": "EffectEvidenceSynthesis.publisher",
 "short": "Name of the publisher (organization or individual)",
 "definition": "The name of the organization or individual that published the effect evidence synthesis.",
 "comment": "Usually an organization but may be an individual. The publisher (or steward) of the effect evidence synthesis is the organization or individual primarily responsible for the maintenance and upkeep of the effect evidence synthesis. This is not necessarily the same individual or organization that developed and initially authored the content. The publisher is the primary point of contact for questions or issues with the effect evidence synthesis. This item SHOULD be populated unless the information is available from context.",
 "requirements": "Helps establish the \"authority/credibility\" of the effect evidence synthesis. May also allow for contact.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.publisher",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.publisher"
 },
 {
 "identity": "w5",
 "map": "FiveWs.witness"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.contact",
 "path": "EffectEvidenceSynthesis.contact",
 "short": "Contact details for the publisher",
 "definition": "Contact details to assist a user in finding and communicating with the publisher.",
 "comment": "May be a web site, an email address, a telephone number, etc.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.contact",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.contact"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.description",
 "path": "EffectEvidenceSynthesis.description",
 "short": "Natural language description of the effect evidence synthesis",
 "definition": "A free text natural language description of the effect evidence synthesis from a consumer's perspective.",
 "comment": "This description can be used to capture details such as why the effect evidence synthesis was built, comments about misuse, instructions for clinical use and interpretation, literature references, examples from the paper world, etc. It is not a rendering of the effect evidence synthesis as conveyed in the 'text' field of the resource itself. This item SHOULD be populated unless the information is available from context (e.g. the language of the effect evidence synthesis is presumed to be the predominant language in the place the effect evidence synthesis was created).",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.description",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "markdown"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.description"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.note",
 "path": "EffectEvidenceSynthesis.note",
 "short": "Used for footnotes or explanatory notes",
 "definition": "A human-readable string to clarify or explain concepts about the resource.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.note",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Annotation"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.useContext",
 "path": "EffectEvidenceSynthesis.useContext",
 "short": "The context that the content is intended to support",
 "definition": "The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.",
 "comment": "When multiple useContexts are specified, there is no expectation that all or any of the contexts apply.",
 "requirements": "Assist in searching for appropriate content.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.useContext",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "UsageContext"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.useContext"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.jurisdiction",
 "path": "EffectEvidenceSynthesis.jurisdiction",
 "short": "Intended jurisdiction for effect evidence synthesis (if applicable)",
 "definition": "A legal or geographic region in which the effect evidence synthesis is intended to be used.",
 "comment": "It may be possible for the effect evidence synthesis to be used in jurisdictions other than those for which it was originally designed or intended.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.jurisdiction",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "Jurisdiction"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
 "valueBoolean": true
 }
 ],
 "strength": "extensible",
 "description": "Countries and regions within which this artifact is targeted for use.",
 "valueSet": "http://hl7.org/fhir/ValueSet/jurisdiction"
 },
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.jurisdiction"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.copyright",
 "path": "EffectEvidenceSynthesis.copyright",
 "short": "Use and/or publishing restrictions",
 "definition": "A copyright statement relating to the effect evidence synthesis and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the effect evidence synthesis.",
 "requirements": "Consumers must be able to determine any legal restrictions on the use of the effect evidence synthesis and/or its content.",
 "alias": [
 "License",
 "Restrictions"
 ],
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.copyright",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "markdown"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.copyright"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.approvalDate",
 "path": "EffectEvidenceSynthesis.approvalDate",
 "short": "When the effect evidence synthesis was approved by publisher",
 "definition": "The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage.",
 "comment": "The 'date' element may be more recent than the approval date because of minor changes or editorial corrections.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.approvalDate",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "date"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.approvalDate"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.lastReviewDate",
 "path": "EffectEvidenceSynthesis.lastReviewDate",
 "short": "When the effect evidence synthesis was last reviewed",
 "definition": "The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.",
 "comment": "If specified, this date follows the original approval date.",
 "requirements": "Gives a sense of how \"current\" the content is. Resources that have not been reviewed in a long time may have a risk of being less appropriate/relevant.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.lastReviewDate",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "date"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.lastReviewDate"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectivePeriod",
 "path": "EffectEvidenceSynthesis.effectivePeriod",
 "short": "When the effect evidence synthesis is expected to be used",
 "definition": "The period during which the effect evidence synthesis content was or is planned to be in active use.",
 "comment": "The effective period for a effect evidence synthesis determines when the content is applicable for usage and is independent of publication and review dates. For example, a measure intended to be used for the year 2016 might be published in 2015.",
 "requirements": "Allows establishing a transition before a resource comes into effect and also allows for a sunsetting process when new versions of the effect evidence synthesis are or are expected to be used instead.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectivePeriod",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Period"
 }
 ],
 "isModifier": false,
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.effectivePeriod"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.topic",
 "path": "EffectEvidenceSynthesis.topic",
 "short": "The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc.",
 "definition": "Descriptive topics related to the content of the EffectEvidenceSynthesis. Topics provide a high-level categorization grouping types of EffectEvidenceSynthesiss that can be useful for filtering and searching.",
 "requirements": "Repositories must be able to determine how to categorize the EffectEvidenceSynthesis so that it can be found by topical searches.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.topic",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "DefinitionTopic"
 }
 ],
 "strength": "example",
 "description": "High-level categorization of the definition, used for searching, sorting, and filtering.",
 "valueSet": "http://hl7.org/fhir/ValueSet/definition-topic"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.author",
 "path": "EffectEvidenceSynthesis.author",
 "short": "Who authored the content",
 "definition": "An individiual or organization primarily involved in the creation and maintenance of the content.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.author",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": ".participation[typeCode=AUT]"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.editor",
 "path": "EffectEvidenceSynthesis.editor",
 "short": "Who edited the content",
 "definition": "An individual or organization primarily responsible for internal coherence of the content.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.editor",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.reviewer",
 "path": "EffectEvidenceSynthesis.reviewer",
 "short": "Who reviewed the content",
 "definition": "An individual or organization primarily responsible for review of some aspect of the content.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.reviewer",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.endorser",
 "path": "EffectEvidenceSynthesis.endorser",
 "short": "Who endorsed the content",
 "definition": "An individual or organization responsible for officially endorsing the content for use in some setting.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.endorser",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.relatedArtifact",
 "path": "EffectEvidenceSynthesis.relatedArtifact",
 "short": "Additional documentation, citations, etc.",
 "definition": "Related artifacts such as additional documentation, justification, or bibliographic references.",
 "comment": "Each related artifact is either an attachment, or a reference to another resource, but not both.",
 "requirements": "EffectEvidenceSynthesiss must be able to provide enough information for consumers of the content (and/or interventions or results produced by the content) to be able to determine and understand the justification for and evidence in support of the content.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.relatedArtifact",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "RelatedArtifact"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.synthesisType",
 "path": "EffectEvidenceSynthesis.synthesisType",
 "short": "Type of synthesis",
 "definition": "Type of synthesis eg meta-analysis.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.synthesisType",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "SynthesisType"
 }
 ],
 "strength": "extensible",
 "description": "Types of combining results from a body of evidence (eg. summary data meta-analysis).",
 "valueSet": "http://hl7.org/fhir/ValueSet/synthesis-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.studyType",
 "path": "EffectEvidenceSynthesis.studyType",
 "short": "Type of study",
 "definition": "Type of study eg randomized trial.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.studyType",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "StudyType"
 }
 ],
 "strength": "extensible",
 "description": "Types of research studies (types of research methods).",
 "valueSet": "http://hl7.org/fhir/ValueSet/study-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.population",
 "path": "EffectEvidenceSynthesis.population",
 "short": "What population?",
 "definition": "A reference to a EvidenceVariable resource that defines the population for the research.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.population",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.exposure",
 "path": "EffectEvidenceSynthesis.exposure",
 "short": "What exposure?",
 "definition": "A reference to a EvidenceVariable resource that defines the exposure for the research.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.exposure",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.exposureAlternative",
 "path": "EffectEvidenceSynthesis.exposureAlternative",
 "short": "What comparison exposure?",
 "definition": "A reference to a EvidenceVariable resource that defines the comparison exposure for the research.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.exposureAlternative",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.outcome",
 "path": "EffectEvidenceSynthesis.outcome",
 "short": "What outcome?",
 "definition": "A reference to a EvidenceVariable resomece that defines the outcome for the research.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.outcome",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize",
 "path": "EffectEvidenceSynthesis.sampleSize",
 "short": "What sample size was involved?",
 "definition": "A description of the size of the sample involved in the synthesis.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.sampleSize",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "Element"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.id",
 "path": "EffectEvidenceSynthesis.sampleSize.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.extension",
 "path": "EffectEvidenceSynthesis.sampleSize.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.modifierExtension",
 "path": "EffectEvidenceSynthesis.sampleSize.modifierExtension",
 "short": "Extensions that cannot be ignored even if unrecognized",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content",
 "modifiers"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "BackboneElement.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
 "isSummary": true,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.description",
 "path": "EffectEvidenceSynthesis.sampleSize.description",
 "short": "Description of sample size",
 "definition": "Human-readable summary of sample size.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.sampleSize.description",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
 "path": "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
 "short": "How many studies?",
 "definition": "Number of studies included in this evidence synthesis.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
 "path": "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
 "short": "How many participants?",
 "definition": "Number of participants included in this evidence synthesis.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure",
 "path": "EffectEvidenceSynthesis.resultsByExposure",
 "short": "What was the result per exposure?",
 "definition": "A description of the results for each exposure considered in the effect estimate.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.resultsByExposure",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "Element"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.id",
 "path": "EffectEvidenceSynthesis.resultsByExposure.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.extension",
 "path": "EffectEvidenceSynthesis.resultsByExposure.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.modifierExtension",
 "path": "EffectEvidenceSynthesis.resultsByExposure.modifierExtension",
 "short": "Extensions that cannot be ignored even if unrecognized",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content",
 "modifiers"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "BackboneElement.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
 "isSummary": true,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.description",
 "path": "EffectEvidenceSynthesis.resultsByExposure.description",
 "short": "Description of results by exposure",
 "definition": "Human-readable summary of results by exposure state.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.resultsByExposure.description",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.exposureState",
 "path": "EffectEvidenceSynthesis.resultsByExposure.exposureState",
 "short": "exposure | exposure-alternative",
 "definition": "Whether these results are for the exposure state or alternative exposure state.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.resultsByExposure.exposureState",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "code"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "ExposureState"
 }
 ],
 "strength": "required",
 "description": "Whether the results by exposure is describing the results for the primary exposure of interest (exposure) or the alternative state (exposureAlternative).",
 "valueSet": "http://hl7.org/fhir/ValueSet/exposure-state|4.0.0"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.variantState",
 "path": "EffectEvidenceSynthesis.resultsByExposure.variantState",
 "short": "Variant exposure states",
 "definition": "Used to define variant exposure states such as low-risk state.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.resultsByExposure.variantState",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "EvidenceVariantState"
 }
 ],
 "strength": "extensible",
 "description": "Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.",
 "valueSet": "http://hl7.org/fhir/ValueSet/evidence-variant-state"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
 "path": "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
 "short": "Risk evidence synthesis",
 "definition": "Reference to a RiskEvidenceSynthesis resource.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/RiskEvidenceSynthesis"
 ]
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate",
 "path": "EffectEvidenceSynthesis.effectEstimate",
 "short": "What was the estimated effect",
 "definition": "The estimated effect of the exposure variant.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "Element"
 }
 ],
 "isModifier": false,
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.id",
 "path": "EffectEvidenceSynthesis.effectEstimate.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.extension",
 "path": "EffectEvidenceSynthesis.effectEstimate.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.modifierExtension",
 "path": "EffectEvidenceSynthesis.effectEstimate.modifierExtension",
 "short": "Extensions that cannot be ignored even if unrecognized",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content",
 "modifiers"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "BackboneElement.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
 "isSummary": true,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.description",
 "path": "EffectEvidenceSynthesis.effectEstimate.description",
 "short": "Description of effect estimate",
 "definition": "Human-readable summary of effect estimate.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.description",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.type",
 "path": "EffectEvidenceSynthesis.effectEstimate.type",
 "short": "Type of efffect estimate",
 "definition": "Examples include relative risk and mean difference.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.type",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "EffectEstimateType"
 }
 ],
 "strength": "extensible",
 "description": "Whether the effect estimate is an absolute effect estimate (absolute difference) or a relative effect estimate (relative difference), and the specific type of effect estimate (eg relative risk or median difference).",
 "valueSet": "http://hl7.org/fhir/ValueSet/effect-estimate-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.variantState",
 "path": "EffectEvidenceSynthesis.effectEstimate.variantState",
 "short": "Variant exposure states",
 "definition": "Used to define variant exposure states such as low-risk state.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.variantState",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "EvidenceVariantState"
 }
 ],
 "strength": "extensible",
 "description": "Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.",
 "valueSet": "http://hl7.org/fhir/ValueSet/evidence-variant-state"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.value",
 "path": "EffectEvidenceSynthesis.effectEstimate.value",
 "short": "Point estimate",
 "definition": "The point estimate of the effect estimate.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.value",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "decimal"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
 "path": "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
 "short": "What unit is the outcome described in?",
 "definition": "Specifies the UCUM unit for the outcome.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "UCUMUnits"
 }
 ],
 "strength": "required",
 "description": "Unified Code for Units of Measure (UCUM).",
 "valueSet": "http://hl7.org/fhir/ValueSet/ucum-units|4.0.0"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
 "short": "How precise the estimate is",
 "definition": "A description of the precision of the estimate for the effect.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "Element"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.id",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.extension",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.modifierExtension",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.modifierExtension",
 "short": "Extensions that cannot be ignored even if unrecognized",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content",
 "modifiers"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "BackboneElement.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
 "isSummary": true,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
 "short": "Type of precision estimate",
 "definition": "Examples include confidence interval and interquartile range.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "PrecisionEstimateType"
 }
 ],
 "strength": "extensible",
 "description": "Method of reporting variability of estimates, such as confidence intervals, interquartile range or standard deviation.",
 "valueSet": "http://hl7.org/fhir/ValueSet/precision-estimate-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
 "short": "Level of confidence interval",
 "definition": "Use 95 for a 95% confidence interval.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "decimal"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.from",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.from",
 "short": "Lower bound",
 "definition": "Lower bound of confidence interval.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.from",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "decimal"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.to",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.to",
 "short": "Upper bound",
 "definition": "Upper bound of confidence interval.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.to",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "decimal"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.certainty",
 "path": "EffectEvidenceSynthesis.certainty",
 "short": "How certain is the effect",
 "definition": "A description of the certainty of the effect estimate.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "Element"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.id",
 "path": "EffectEvidenceSynthesis.certainty.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.extension",
 "path": "EffectEvidenceSynthesis.certainty.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.modifierExtension",
 "path": "EffectEvidenceSynthesis.certainty.modifierExtension",
 "short": "Extensions that cannot be ignored even if unrecognized",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content",
 "modifiers"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "BackboneElement.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
 "isSummary": true,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.rating",
 "path": "EffectEvidenceSynthesis.certainty.rating",
 "short": "Certainty rating",
 "definition": "A rating of the certainty of the effect estimate.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty.rating",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "QualityOfEvidenceRating"
 }
 ],
 "strength": "extensible",
 "description": "The quality of the evidence described. The code system used specifies the quality scale used to grade this evidence source while the code specifies the actual quality score (represented as a coded value) associated with the evidence.",
 "valueSet": "http://hl7.org/fhir/ValueSet/evidence-quality"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.note",
 "path": "EffectEvidenceSynthesis.certainty.note",
 "short": "Used for footnotes or explanatory notes",
 "definition": "A human-readable string to clarify or explain concepts about the resource.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty.note",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Annotation"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent",
 "short": "A component that contributes to the overall certainty",
 "definition": "A description of a component of the overall certainty.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "Element"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.id",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.extension",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.extension",
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.modifierExtension",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.modifierExtension",
 "short": "Extensions that cannot be ignored even if unrecognized",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
 "alias": [
 "extensions",
 "user content",
 "modifiers"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "BackboneElement.modifierExtension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "isModifier": true,
 "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
 "isSummary": true,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.type",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.type",
 "short": "Type of subcomponent of certainty rating",
 "definition": "Type of subcomponent of certainty rating.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.type",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "CertaintySubcomponentType"
 }
 ],
 "strength": "extensible",
 "description": "The subcomponent classification of quality of evidence rating systems.",
 "valueSet": "http://hl7.org/fhir/ValueSet/certainty-subcomponent-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.rating",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.rating",
 "short": "Subcomponent certainty rating",
 "definition": "A rating of a subcomponent of rating certainty.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.rating",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "CertaintySubcomponentRating"
 }
 ],
 "strength": "extensible",
 "description": "The quality rating of the subcomponent of a quality of evidence rating.",
 "valueSet": "http://hl7.org/fhir/ValueSet/certainty-subcomponent-rating"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.note",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.note",
 "short": "Used for footnotes or explanatory notes",
 "definition": "A human-readable string to clarify or explain concepts about the resource.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.note",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Annotation"
 }
 ],
 "isModifier": false,
 "isSummary": false
 }
 ]
 },
 "differential": {
 "element": [
 {
 "id": "EffectEvidenceSynthesis",
 "path": "EffectEvidenceSynthesis",
 "short": "A quantified estimate of effect based on a body of evidence",
 "definition": "The EffectEvidenceSynthesis resource describes the difference in an outcome between exposures states in a population where the effect estimate is derived from a combination of research studies.",
 "min": 0,
 "max": "*",
 "constraint": [
 {
 "key": "ees-0",
 "severity": "warning",
 "human": "Name should be usable as an identifier for the module by machine processing applications such as code generation",
 "expression": "name.matches('[A-Z]([A-Za-z0-9_]){0,254}')",
 "xpath": "not(exists(f:name/@value)) or matches(f:name/@value, '[A-Z]([A-Za-z0-9_]){0,254}')"
 }
 ],
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.url",
 "path": "EffectEvidenceSynthesis.url",
 "short": "Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique)",
 "definition": "An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.",
 "comment": "Can be a urn:uuid: or a urn:oid: but real http: addresses are preferred. Multiple instances may share the same URL if they have a distinct version.\n\nThe determination of when to create a new version of a resource (same url, new version) vs. defining a new artifact is up to the author. Considerations for making this decision are found in [Technical and Business Versions](resource.html#versions). \n\nIn some cases, the resource can no longer be found at the stated url, but the url itself cannot change. Implementations can use the [meta.source](resource.html#meta) element to indicate where the current master source of the resource can be found.",
 "requirements": "Allows the effect evidence synthesis to be referenced by a single globally unique identifier.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "uri"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.url"
 },
 {
 "identity": "w5",
 "map": "FiveWs.identifier"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.identifier",
 "path": "EffectEvidenceSynthesis.identifier",
 "short": "Additional identifier for the effect evidence synthesis",
 "definition": "A formal identifier that is used to identify this effect evidence synthesis when it is represented in other formats, or referenced in a specification, model, design or an instance.",
 "comment": "Typically, this is used for identifiers that can go in an HL7 V3 II (instance identifier) data type, and can then identify this effect evidence synthesis outside of FHIR, where it is not possible to use the logical URI.",
 "requirements": "Allows externally provided and/or usable business identifiers to be easily associated with the module.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "Identifier"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.identifier"
 },
 {
 "identity": "w5",
 "map": "FiveWs.identifier"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.version",
 "path": "EffectEvidenceSynthesis.version",
 "short": "Business version of the effect evidence synthesis",
 "definition": "The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.",
 "comment": "There may be different effect evidence synthesis instances that have the same identifier but different versions. The version can be appended to the url in a reference to allow a reference to a particular business version of the effect evidence synthesis with the format [url]|[version].",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.version"
 },
 {
 "identity": "w5",
 "map": "FiveWs.version"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.name",
 "path": "EffectEvidenceSynthesis.name",
 "short": "Name for this effect evidence synthesis (computer friendly)",
 "definition": "A natural language name identifying the effect evidence synthesis. This name should be usable as an identifier for the module by machine processing applications such as code generation.",
 "comment": "The name is not expected to be globally unique. The name should be a simple alphanumeric type name to ensure that it is machine-processing friendly.",
 "requirements": "Support human navigation and code generation.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ],
 "condition": [
 "inv-0"
 ],
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.title",
 "path": "EffectEvidenceSynthesis.title",
 "short": "Name for this effect evidence synthesis (human friendly)",
 "definition": "A short, descriptive, user-friendly title for the effect evidence synthesis.",
 "comment": "This name does not need to be machine-processing friendly and may contain punctuation, white-space, etc.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.title"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.status",
 "path": "EffectEvidenceSynthesis.status",
 "short": "draft | active | retired | unknown",
 "definition": "The status of this effect evidence synthesis. Enables tracking the life-cycle of the content.",
 "comment": "Allows filtering of effect evidence synthesiss that are appropriate for use versus not.",
 "min": 1,
 "max": "1",
 "type": [
 {
 "code": "code"
 }
 ],
 "isModifier": true,
 "isModifierReason": "This is labeled as \"Is Modifier\" because applications should not use a retired {{title}} without due consideration",
 "isSummary": true,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "PublicationStatus"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
 "valueBoolean": true
 }
 ],
 "strength": "required",
 "description": "The lifecycle status of an artifact.",
 "valueSet": "http://hl7.org/fhir/ValueSet/publication-status|4.0.0"
 },
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.status"
 },
 {
 "identity": "w5",
 "map": "FiveWs.status"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.date",
 "path": "EffectEvidenceSynthesis.date",
 "short": "Date last changed",
 "definition": "The date (and optionally time) when the effect evidence synthesis was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the effect evidence synthesis changes.",
 "comment": "Note that this is not the same as the resource last-modified-date, since the resource may be a secondary representation of the effect evidence synthesis. Additional specific dates may be added as extensions or be found by consulting Provenances associated with past versions of the resource.",
 "alias": [
 "Revision Date"
 ],
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "dateTime"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.date"
 },
 {
 "identity": "w5",
 "map": "FiveWs.recorded"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.publisher",
 "path": "EffectEvidenceSynthesis.publisher",
 "short": "Name of the publisher (organization or individual)",
 "definition": "The name of the organization or individual that published the effect evidence synthesis.",
 "comment": "Usually an organization but may be an individual. The publisher (or steward) of the effect evidence synthesis is the organization or individual primarily responsible for the maintenance and upkeep of the effect evidence synthesis. This is not necessarily the same individual or organization that developed and initially authored the content. The publisher is the primary point of contact for questions or issues with the effect evidence synthesis. This item SHOULD be populated unless the information is available from context.",
 "requirements": "Helps establish the \"authority/credibility\" of the effect evidence synthesis. May also allow for contact.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.publisher"
 },
 {
 "identity": "w5",
 "map": "FiveWs.witness"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.contact",
 "path": "EffectEvidenceSynthesis.contact",
 "short": "Contact details for the publisher",
 "definition": "Contact details to assist a user in finding and communicating with the publisher.",
 "comment": "May be a web site, an email address, a telephone number, etc.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.contact"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.description",
 "path": "EffectEvidenceSynthesis.description",
 "short": "Natural language description of the effect evidence synthesis",
 "definition": "A free text natural language description of the effect evidence synthesis from a consumer's perspective.",
 "comment": "This description can be used to capture details such as why the effect evidence synthesis was built, comments about misuse, instructions for clinical use and interpretation, literature references, examples from the paper world, etc. It is not a rendering of the effect evidence synthesis as conveyed in the 'text' field of the resource itself. This item SHOULD be populated unless the information is available from context (e.g. the language of the effect evidence synthesis is presumed to be the predominant language in the place the effect evidence synthesis was created).",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "markdown"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.description"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.note",
 "path": "EffectEvidenceSynthesis.note",
 "short": "Used for footnotes or explanatory notes",
 "definition": "A human-readable string to clarify or explain concepts about the resource.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "Annotation"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.useContext",
 "path": "EffectEvidenceSynthesis.useContext",
 "short": "The context that the content is intended to support",
 "definition": "The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.",
 "comment": "When multiple useContexts are specified, there is no expectation that all or any of the contexts apply.",
 "requirements": "Assist in searching for appropriate content.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "UsageContext"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.useContext"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.jurisdiction",
 "path": "EffectEvidenceSynthesis.jurisdiction",
 "short": "Intended jurisdiction for effect evidence synthesis (if applicable)",
 "definition": "A legal or geographic region in which the effect evidence synthesis is intended to be used.",
 "comment": "It may be possible for the effect evidence synthesis to be used in jurisdictions other than those for which it was originally designed or intended.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "isSummary": true,
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "Jurisdiction"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
 "valueBoolean": true
 }
 ],
 "strength": "extensible",
 "description": "Countries and regions within which this artifact is targeted for use.",
 "valueSet": "http://hl7.org/fhir/ValueSet/jurisdiction"
 },
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.jurisdiction"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.copyright",
 "path": "EffectEvidenceSynthesis.copyright",
 "short": "Use and/or publishing restrictions",
 "definition": "A copyright statement relating to the effect evidence synthesis and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the effect evidence synthesis.",
 "requirements": "Consumers must be able to determine any legal restrictions on the use of the effect evidence synthesis and/or its content.",
 "alias": [
 "License",
 "Restrictions"
 ],
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "markdown"
 }
 ],
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.copyright"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.approvalDate",
 "path": "EffectEvidenceSynthesis.approvalDate",
 "short": "When the effect evidence synthesis was approved by publisher",
 "definition": "The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage.",
 "comment": "The 'date' element may be more recent than the approval date because of minor changes or editorial corrections.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "date"
 }
 ],
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.approvalDate"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.lastReviewDate",
 "path": "EffectEvidenceSynthesis.lastReviewDate",
 "short": "When the effect evidence synthesis was last reviewed",
 "definition": "The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.",
 "comment": "If specified, this date follows the original approval date.",
 "requirements": "Gives a sense of how \"current\" the content is. Resources that have not been reviewed in a long time may have a risk of being less appropriate/relevant.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "date"
 }
 ],
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.lastReviewDate"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectivePeriod",
 "path": "EffectEvidenceSynthesis.effectivePeriod",
 "short": "When the effect evidence synthesis is expected to be used",
 "definition": "The period during which the effect evidence synthesis content was or is planned to be in active use.",
 "comment": "The effective period for a effect evidence synthesis determines when the content is applicable for usage and is independent of publication and review dates. For example, a measure intended to be used for the year 2016 might be published in 2015.",
 "requirements": "Allows establishing a transition before a resource comes into effect and also allows for a sunsetting process when new versions of the effect evidence synthesis are or are expected to be used instead.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "Period"
 }
 ],
 "isSummary": true,
 "mapping": [
 {
 "identity": "workflow",
 "map": "Definition.effectivePeriod"
 },
 {
 "identity": "objimpl",
 "map": "no-gen-base"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.topic",
 "path": "EffectEvidenceSynthesis.topic",
 "short": "The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc.",
 "definition": "Descriptive topics related to the content of the EffectEvidenceSynthesis. Topics provide a high-level categorization grouping types of EffectEvidenceSynthesiss that can be useful for filtering and searching.",
 "requirements": "Repositories must be able to determine how to categorize the EffectEvidenceSynthesis so that it can be found by topical searches.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "DefinitionTopic"
 }
 ],
 "strength": "example",
 "description": "High-level categorization of the definition, used for searching, sorting, and filtering.",
 "valueSet": "http://hl7.org/fhir/ValueSet/definition-topic"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.author",
 "path": "EffectEvidenceSynthesis.author",
 "short": "Who authored the content",
 "definition": "An individiual or organization primarily involved in the creation and maintenance of the content.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "mapping": [
 {
 "identity": "rim",
 "map": ".participation[typeCode=AUT]"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.editor",
 "path": "EffectEvidenceSynthesis.editor",
 "short": "Who edited the content",
 "definition": "An individual or organization primarily responsible for internal coherence of the content.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "ContactDetail"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.reviewer",
 "path": "EffectEvidenceSynthesis.reviewer",
 "short": "Who reviewed the content",
 "definition": "An individual or organization primarily responsible for review of some aspect of the content.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "mapping": [
 {
 "identity": "rim",
 "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.endorser",
 "path": "EffectEvidenceSynthesis.endorser",
 "short": "Who endorsed the content",
 "definition": "An individual or organization responsible for officially endorsing the content for use in some setting.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "ContactDetail"
 }
 ],
 "mapping": [
 {
 "identity": "rim",
 "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.relatedArtifact",
 "path": "EffectEvidenceSynthesis.relatedArtifact",
 "short": "Additional documentation, citations, etc.",
 "definition": "Related artifacts such as additional documentation, justification, or bibliographic references.",
 "comment": "Each related artifact is either an attachment, or a reference to another resource, but not both.",
 "requirements": "EffectEvidenceSynthesiss must be able to provide enough information for consumers of the content (and/or interventions or results produced by the content) to be able to determine and understand the justification for and evidence in support of the content.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "RelatedArtifact"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.synthesisType",
 "path": "EffectEvidenceSynthesis.synthesisType",
 "short": "Type of synthesis",
 "definition": "Type of synthesis eg meta-analysis.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "SynthesisType"
 }
 ],
 "strength": "extensible",
 "description": "Types of combining results from a body of evidence (eg. summary data meta-analysis).",
 "valueSet": "http://hl7.org/fhir/ValueSet/synthesis-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.studyType",
 "path": "EffectEvidenceSynthesis.studyType",
 "short": "Type of study",
 "definition": "Type of study eg randomized trial.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "StudyType"
 }
 ],
 "strength": "extensible",
 "description": "Types of research studies (types of research methods).",
 "valueSet": "http://hl7.org/fhir/ValueSet/study-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.population",
 "path": "EffectEvidenceSynthesis.population",
 "short": "What population?",
 "definition": "A reference to a EvidenceVariable resource that defines the population for the research.",
 "min": 1,
 "max": "1",
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.exposure",
 "path": "EffectEvidenceSynthesis.exposure",
 "short": "What exposure?",
 "definition": "A reference to a EvidenceVariable resource that defines the exposure for the research.",
 "min": 1,
 "max": "1",
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.exposureAlternative",
 "path": "EffectEvidenceSynthesis.exposureAlternative",
 "short": "What comparison exposure?",
 "definition": "A reference to a EvidenceVariable resource that defines the comparison exposure for the research.",
 "min": 1,
 "max": "1",
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.outcome",
 "path": "EffectEvidenceSynthesis.outcome",
 "short": "What outcome?",
 "definition": "A reference to a EvidenceVariable resomece that defines the outcome for the research.",
 "min": 1,
 "max": "1",
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
 ]
 }
 ],
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize",
 "path": "EffectEvidenceSynthesis.sampleSize",
 "short": "What sample size was involved?",
 "definition": "A description of the size of the sample involved in the synthesis.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "BackboneElement"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.description",
 "path": "EffectEvidenceSynthesis.sampleSize.description",
 "short": "Description of sample size",
 "definition": "Human-readable summary of sample size.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
 "path": "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
 "short": "How many studies?",
 "definition": "Number of studies included in this evidence synthesis.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "integer"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
 "path": "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
 "short": "How many participants?",
 "definition": "Number of participants included in this evidence synthesis.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "integer"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure",
 "path": "EffectEvidenceSynthesis.resultsByExposure",
 "short": "What was the result per exposure?",
 "definition": "A description of the results for each exposure considered in the effect estimate.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "BackboneElement"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.description",
 "path": "EffectEvidenceSynthesis.resultsByExposure.description",
 "short": "Description of results by exposure",
 "definition": "Human-readable summary of results by exposure state.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.exposureState",
 "path": "EffectEvidenceSynthesis.resultsByExposure.exposureState",
 "short": "exposure | exposure-alternative",
 "definition": "Whether these results are for the exposure state or alternative exposure state.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "code"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "ExposureState"
 }
 ],
 "strength": "required",
 "description": "Whether the results by exposure is describing the results for the primary exposure of interest (exposure) or the alternative state (exposureAlternative).",
 "valueSet": "http://hl7.org/fhir/ValueSet/exposure-state|4.0.0"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.variantState",
 "path": "EffectEvidenceSynthesis.resultsByExposure.variantState",
 "short": "Variant exposure states",
 "definition": "Used to define variant exposure states such as low-risk state.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "EvidenceVariantState"
 }
 ],
 "strength": "extensible",
 "description": "Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.",
 "valueSet": "http://hl7.org/fhir/ValueSet/evidence-variant-state"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
 "path": "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
 "short": "Risk evidence synthesis",
 "definition": "Reference to a RiskEvidenceSynthesis resource.",
 "min": 1,
 "max": "1",
 "type": [
 {
 "code": "Reference",
 "targetProfile": [
 "http://hl7.org/fhir/StructureDefinition/RiskEvidenceSynthesis"
 ]
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate",
 "path": "EffectEvidenceSynthesis.effectEstimate",
 "short": "What was the estimated effect",
 "definition": "The estimated effect of the exposure variant.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "BackboneElement"
 }
 ],
 "isSummary": true
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.description",
 "path": "EffectEvidenceSynthesis.effectEstimate.description",
 "short": "Description of effect estimate",
 "definition": "Human-readable summary of effect estimate.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.type",
 "path": "EffectEvidenceSynthesis.effectEstimate.type",
 "short": "Type of efffect estimate",
 "definition": "Examples include relative risk and mean difference.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "EffectEstimateType"
 }
 ],
 "strength": "extensible",
 "description": "Whether the effect estimate is an absolute effect estimate (absolute difference) or a relative effect estimate (relative difference), and the specific type of effect estimate (eg relative risk or median difference).",
 "valueSet": "http://hl7.org/fhir/ValueSet/effect-estimate-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.variantState",
 "path": "EffectEvidenceSynthesis.effectEstimate.variantState",
 "short": "Variant exposure states",
 "definition": "Used to define variant exposure states such as low-risk state.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "EvidenceVariantState"
 }
 ],
 "strength": "extensible",
 "description": "Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.",
 "valueSet": "http://hl7.org/fhir/ValueSet/evidence-variant-state"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.value",
 "path": "EffectEvidenceSynthesis.effectEstimate.value",
 "short": "Point estimate",
 "definition": "The point estimate of the effect estimate.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "decimal"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
 "path": "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
 "short": "What unit is the outcome described in?",
 "definition": "Specifies the UCUM unit for the outcome.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "UCUMUnits"
 }
 ],
 "strength": "required",
 "description": "Unified Code for Units of Measure (UCUM).",
 "valueSet": "http://hl7.org/fhir/ValueSet/ucum-units|4.0.0"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
 "short": "How precise the estimate is",
 "definition": "A description of the precision of the estimate for the effect.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "BackboneElement"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
 "short": "Type of precision estimate",
 "definition": "Examples include confidence interval and interquartile range.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "PrecisionEstimateType"
 }
 ],
 "strength": "extensible",
 "description": "Method of reporting variability of estimates, such as confidence intervals, interquartile range or standard deviation.",
 "valueSet": "http://hl7.org/fhir/ValueSet/precision-estimate-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
 "short": "Level of confidence interval",
 "definition": "Use 95 for a 95% confidence interval.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "decimal"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.from",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.from",
 "short": "Lower bound",
 "definition": "Lower bound of confidence interval.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "decimal"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.to",
 "path": "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.to",
 "short": "Upper bound",
 "definition": "Upper bound of confidence interval.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "decimal"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty",
 "path": "EffectEvidenceSynthesis.certainty",
 "short": "How certain is the effect",
 "definition": "A description of the certainty of the effect estimate.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "BackboneElement"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.rating",
 "path": "EffectEvidenceSynthesis.certainty.rating",
 "short": "Certainty rating",
 "definition": "A rating of the certainty of the effect estimate.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "QualityOfEvidenceRating"
 }
 ],
 "strength": "extensible",
 "description": "The quality of the evidence described. The code system used specifies the quality scale used to grade this evidence source while the code specifies the actual quality score (represented as a coded value) associated with the evidence.",
 "valueSet": "http://hl7.org/fhir/ValueSet/evidence-quality"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.note",
 "path": "EffectEvidenceSynthesis.certainty.note",
 "short": "Used for footnotes or explanatory notes",
 "definition": "A human-readable string to clarify or explain concepts about the resource.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "Annotation"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent",
 "short": "A component that contributes to the overall certainty",
 "definition": "A description of a component of the overall certainty.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "BackboneElement"
 }
 ]
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.type",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.type",
 "short": "Type of subcomponent of certainty rating",
 "definition": "Type of subcomponent of certainty rating.",
 "min": 0,
 "max": "1",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "CertaintySubcomponentType"
 }
 ],
 "strength": "extensible",
 "description": "The subcomponent classification of quality of evidence rating systems.",
 "valueSet": "http://hl7.org/fhir/ValueSet/certainty-subcomponent-type"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.rating",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.rating",
 "short": "Subcomponent certainty rating",
 "definition": "A rating of a subcomponent of rating certainty.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "binding": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
 "valueString": "CertaintySubcomponentRating"
 }
 ],
 "strength": "extensible",
 "description": "The quality rating of the subcomponent of a quality of evidence rating.",
 "valueSet": "http://hl7.org/fhir/ValueSet/certainty-subcomponent-rating"
 }
 },
 {
 "id": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.note",
 "path": "EffectEvidenceSynthesis.certainty.certaintySubcomponent.note",
 "short": "Used for footnotes or explanatory notes",
 "definition": "A human-readable string to clarify or explain concepts about the resource.",
 "min": 0,
 "max": "*",
 "type": [
 {
 "code": "Annotation"
 }
 ]
 }
 ]
 }
}

name : EffectEvidenceSynthesis

{

}