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{
  "resourceType": "StructureDefinition",
  "id": "synthesis",
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 0
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "cds"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use"
    }
  ],
  "url": "http://hl7.org/fhir/StructureDefinition/synthesis",
  "version": "4.0.1",
  "name": "Evidence Synthesis Profile",
  "status": "draft",
  "experimental": false,
  "date": "2018-10-31",
  "publisher": "Health Level Seven, Inc. - Clinical Decision Support Workgroup",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/dss/index.cfm"
        }
      ]
    }
  ],
  "description": "Explanation of what this profile contains/is for.",
  "purpose": "Need to be able to define and reuse the definition of individual elements of a research question.",
  "fhirVersion": "4.0.1",
  "mapping": [
    {
      "identity": "workflow",
      "uri": "http://hl7.org/fhir/workflow",
      "name": "Workflow Pattern"
    },
    {
      "identity": "w5",
      "uri": "http://hl7.org/fhir/fivews",
      "name": "FiveWs Pattern Mapping"
    },
    {
      "identity": "objimpl",
      "uri": "http://hl7.org/fhir/object-implementation",
      "name": "Object Implementation Information"
    },
    {
      "identity": "rim",
      "uri": "http://hl7.org/v3",
      "name": "RIM Mapping"
    }
  ],
  "kind": "resource",
  "abstract": false,
  "type": "Evidence",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Evidence",
  "derivation": "constraint",
  "snapshot": {
    "element": [
      {
        "id": "Evidence",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-display-hint",
            "valueString": "0;0"
          }
        ],
        "path": "Evidence",
        "short": "A research context or question",
        "definition": "The Evidence resource describes the conditional state (population and any exposures being compared within the population) and outcome (if specified) that the knowledge (evidence, assertion, recommendation) is about.",
        "comment": "PICO stands for Population (the population within which exposures are being compared), Intervention (the conditional state or exposure state being described for its effect on outcomes), Comparison (the alternative conditional state or alternative exposure state being compared against), and Outcome (the result or effect of the intervention in the population).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence",
          "min": 0,
          "max": "*"
        },
        "constraint": [
          {
            "key": "dom-2",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
            "expression": "contained.contained.empty()",
            "xpath": "not(parent::f:contained and f:contained)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-3",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
            "expression": "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
            "xpath": "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-4",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
            "expression": "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-5",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a security label",
            "expression": "contained.meta.security.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:security))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
                "valueBoolean": true
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
                "valueMarkdown": "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
              }
            ],
            "key": "dom-6",
            "severity": "warning",
            "human": "A resource should have narrative for robust management",
            "expression": "text.`div`.exists()",
            "xpath": "exists(f:text/h:div)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "evi-0",
            "severity": "warning",
            "human": "Name should be usable as an identifier for the module by machine processing applications such as code generation",
            "expression": "name.matches('[A-Z]([A-Za-z0-9_]){0,254}')",
            "xpath": "not(exists(f:name/@value)) or matches(f:name/@value, '[A-Z]([A-Za-z0-9_]){0,254}')",
            "source": "http://hl7.org/fhir/StructureDefinition/Evidence"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "workflow",
            "map": "Definition"
          }
        ]
      },
      {
        "id": "Evidence.id",
        "path": "Evidence.id",
        "short": "Logical id of this artifact",
        "definition": "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
        "comment": "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isModifier": false,
        "isSummary": true
      },
      {
        "id": "Evidence.meta",
        "path": "Evidence.meta",
        "short": "Metadata about the resource",
        "definition": "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.meta",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Meta"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true
      },
      {
        "id": "Evidence.implicitRules",
        "path": "Evidence.implicitRules",
        "short": "A set of rules under which this content was created",
        "definition": "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
        "comment": "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.implicitRules",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
        "isSummary": true
      },
      {
        "id": "Evidence.language",
        "path": "Evidence.language",
        "short": "Language of the resource content",
        "definition": "The base language in which the resource is written.",
        "comment": "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.language",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
              "valueCanonical": "http://hl7.org/fhir/ValueSet/all-languages"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Language"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean": true
            }
          ],
          "strength": "preferred",
          "description": "A human language.",
          "valueSet": "http://hl7.org/fhir/ValueSet/languages"
        }
      },
      {
        "id": "Evidence.text",
        "path": "Evidence.text",
        "short": "Text summary of the resource, for human interpretation",
        "definition": "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
        "comment": "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
        "alias": [
          "narrative",
          "html",
          "xhtml",
          "display"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "DomainResource.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Narrative"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "Act.text?"
          }
        ]
      },
      {
        "id": "Evidence.contained",
        "path": "Evidence.contained",
        "short": "Contained, inline Resources",
        "definition": "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
        "comment": "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
        "alias": [
          "inline resources",
          "anonymous resources",
          "contained resources"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.contained",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Resource"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Evidence.extension",
        "path": "Evidence.extension",
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Evidence.modifierExtension",
        "path": "Evidence.modifierExtension",
        "short": "Extensions that cannot be ignored",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "Evidence.url",
        "path": "Evidence.url",
        "short": "Canonical identifier for this evidence, represented as a URI (globally unique)",
        "definition": "An absolute URI that is used to identify this evidence when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this evidence is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the evidence is stored on different servers.",
        "comment": "Can be a urn:uuid: or a urn:oid: but real http: addresses are preferred.  Multiple instances may share the same URL if they have a distinct version.\n\nThe determination of when to create a new version of a resource (same url, new version) vs. defining a new artifact is up to the author.  Considerations for making this decision are found in [Technical and Business Versions](resource.html#versions). \n\nIn some cases, the resource can no longer be found at the stated url, but the url itself cannot change. Implementations can use the [meta.source](resource.html#meta) element to indicate where the current master source of the resource can be found.",
        "requirements": "Allows the evidence to be referenced by a single globally unique identifier.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.url",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.url"
          },
          {
            "identity": "w5",
            "map": "FiveWs.identifier"
          }
        ]
      },
      {
        "id": "Evidence.identifier",
        "path": "Evidence.identifier",
        "short": "Additional identifier for the evidence",
        "definition": "A formal identifier that is used to identify this evidence when it is represented in other formats, or referenced in a specification, model, design or an instance.",
        "comment": "Typically, this is used for identifiers that can go in an HL7 V3 II (instance identifier) data type, and can then identify this evidence outside of FHIR, where it is not possible to use the logical URI.",
        "requirements": "Allows externally provided and/or usable business identifiers to be easily associated with the module.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.identifier",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Identifier"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.identifier"
          },
          {
            "identity": "w5",
            "map": "FiveWs.identifier"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.version",
        "path": "Evidence.version",
        "short": "Business version of the evidence",
        "definition": "The identifier that is used to identify this version of the evidence when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the evidence author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.",
        "comment": "There may be different evidence instances that have the same identifier but different versions.  The version can be appended to the url in a reference to allow a reference to a particular business version of the evidence with the format [url]|[version].",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.version",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.version"
          },
          {
            "identity": "w5",
            "map": "FiveWs.version"
          }
        ]
      },
      {
        "id": "Evidence.name",
        "path": "Evidence.name",
        "short": "Name for this evidence (computer friendly)",
        "definition": "A natural language name identifying the evidence. This name should be usable as an identifier for the module by machine processing applications such as code generation.",
        "comment": "The name is not expected to be globally unique. The name should be a simple alphanumeric type name to ensure that it is machine-processing friendly.",
        "requirements": "Support human navigation and code generation.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.name",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "inv-0"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true
      },
      {
        "id": "Evidence.title",
        "path": "Evidence.title",
        "short": "Name for this evidence (human friendly)",
        "definition": "A short, descriptive, user-friendly title for the evidence.",
        "comment": "This name does not need to be machine-processing friendly and may contain punctuation, white-space, etc.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.title",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.title"
          }
        ]
      },
      {
        "id": "Evidence.shortTitle",
        "path": "Evidence.shortTitle",
        "short": "Title for use in informal contexts",
        "definition": "The short title provides an alternate title for use in informal descriptive contexts where the full, formal title is not necessary.",
        "requirements": "Need to be able to reference the content by a short description, but still provide a longer, more formal title for the content.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.shortTitle",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.title"
          }
        ]
      },
      {
        "id": "Evidence.subtitle",
        "path": "Evidence.subtitle",
        "short": "Subordinate title of the Evidence",
        "definition": "An explanatory or alternate title for the Evidence giving additional information about its content.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.subtitle",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Evidence.status",
        "path": "Evidence.status",
        "short": "draft | active | retired | unknown",
        "definition": "The status of this evidence. Enables tracking the life-cycle of the content.",
        "comment": "Allows filtering of evidences that are appropriate for use versus not.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Evidence.status",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This is labeled as \"Is Modifier\" because applications should not use a retired {{title}} without due consideration",
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "PublicationStatus"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean": true
            }
          ],
          "strength": "required",
          "description": "The lifecycle status of an artifact.",
          "valueSet": "http://hl7.org/fhir/ValueSet/publication-status|4.0.1"
        },
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.status"
          },
          {
            "identity": "w5",
            "map": "FiveWs.status"
          }
        ]
      },
      {
        "id": "Evidence.date",
        "path": "Evidence.date",
        "short": "Date last changed",
        "definition": "The date  (and optionally time) when the evidence was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the evidence changes.",
        "comment": "Note that this is not the same as the resource last-modified-date, since the resource may be a secondary representation of the evidence. Additional specific dates may be added as extensions or be found by consulting Provenances associated with past versions of the resource.",
        "alias": [
          "Revision Date"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.date",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.date"
          },
          {
            "identity": "w5",
            "map": "FiveWs.recorded"
          }
        ]
      },
      {
        "id": "Evidence.publisher",
        "path": "Evidence.publisher",
        "short": "Name of the publisher (organization or individual)",
        "definition": "The name of the organization or individual that published the evidence.",
        "comment": "Usually an organization but may be an individual. The publisher (or steward) of the evidence is the organization or individual primarily responsible for the maintenance and upkeep of the evidence. This is not necessarily the same individual or organization that developed and initially authored the content. The publisher is the primary point of contact for questions or issues with the evidence. This item SHOULD be populated unless the information is available from context.",
        "requirements": "Helps establish the \"authority/credibility\" of the evidence.  May also allow for contact.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.publisher",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.publisher"
          },
          {
            "identity": "w5",
            "map": "FiveWs.witness"
          }
        ]
      },
      {
        "id": "Evidence.contact",
        "path": "Evidence.contact",
        "short": "Contact details for the publisher",
        "definition": "Contact details to assist a user in finding and communicating with the publisher.",
        "comment": "May be a web site, an email address, a telephone number, etc.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.contact",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.contact"
          }
        ]
      },
      {
        "id": "Evidence.description",
        "path": "Evidence.description",
        "short": "Natural language description of the evidence",
        "definition": "A free text natural language description of the evidence from a consumer's perspective.",
        "comment": "This description can be used to capture details such as why the evidence was built, comments about misuse, instructions for clinical use and interpretation, literature references, examples from the paper world, etc. It is not a rendering of the evidence as conveyed in the 'text' field of the resource itself. This item SHOULD be populated unless the information is available from context (e.g. the language of the evidence is presumed to be the predominant language in the place the evidence was created).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.description",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.description"
          }
        ]
      },
      {
        "id": "Evidence.note",
        "path": "Evidence.note",
        "short": "Used for footnotes or explanatory notes",
        "definition": "A human-readable string to clarify or explain concepts about the resource.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.note",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Evidence.useContext",
        "path": "Evidence.useContext",
        "short": "The context that the content is intended to support",
        "definition": "The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate evidence instances.",
        "comment": "When multiple useContexts are specified, there is no expectation that all or any of the contexts apply.",
        "requirements": "Assist in searching for appropriate content.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.useContext",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "UsageContext"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.useContext"
          }
        ]
      },
      {
        "id": "Evidence.jurisdiction",
        "path": "Evidence.jurisdiction",
        "short": "Intended jurisdiction for evidence (if applicable)",
        "definition": "A legal or geographic region in which the evidence is intended to be used.",
        "comment": "It may be possible for the evidence to be used in jurisdictions other than those for which it was originally designed or intended.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.jurisdiction",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Jurisdiction"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean": true
            }
          ],
          "strength": "extensible",
          "description": "Countries and regions within which this artifact is targeted for use.",
          "valueSet": "http://hl7.org/fhir/ValueSet/jurisdiction"
        },
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.jurisdiction"
          }
        ]
      },
      {
        "id": "Evidence.copyright",
        "path": "Evidence.copyright",
        "short": "Use and/or publishing restrictions",
        "definition": "A copyright statement relating to the evidence and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the evidence.",
        "requirements": "Consumers must be able to determine any legal restrictions on the use of the evidence and/or its content.",
        "alias": [
          "License",
          "Restrictions"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.copyright",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "markdown"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.copyright"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.approvalDate",
        "path": "Evidence.approvalDate",
        "short": "When the evidence was approved by publisher",
        "definition": "The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage.",
        "comment": "The 'date' element may be more recent than the approval date because of minor changes or editorial corrections.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.approvalDate",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "date"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.approvalDate"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.lastReviewDate",
        "path": "Evidence.lastReviewDate",
        "short": "When the evidence was last reviewed",
        "definition": "The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.",
        "comment": "If specified, this date follows the original approval date.",
        "requirements": "Gives a sense of how \"current\" the content is.  Resources that have not been reviewed in a long time may have a risk of being less appropriate/relevant.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.lastReviewDate",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "date"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.lastReviewDate"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.effectivePeriod",
        "path": "Evidence.effectivePeriod",
        "short": "When the evidence is expected to be used",
        "definition": "The period during which the evidence content was or is planned to be in active use.",
        "comment": "The effective period for a evidence  determines when the content is applicable for usage and is independent of publication and review dates. For example, a measure intended to be used for the year 2016 might be published in 2015.",
        "requirements": "Allows establishing a transition before a resource comes into effect and also allows for a sunsetting  process when new versions of the evidence are or are expected to be used instead.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Evidence.effectivePeriod",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Period"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.effectivePeriod"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.topic",
        "path": "Evidence.topic",
        "short": "The category of the Evidence, such as Education, Treatment, Assessment, etc.",
        "definition": "Descriptive topics related to the content of the Evidence. Topics provide a high-level categorization grouping types of Evidences that can be useful for filtering and searching.",
        "requirements": "Repositories must be able to determine how to categorize the Evidence so that it can be found by topical searches.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.topic",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "DefinitionTopic"
            }
          ],
          "strength": "example",
          "description": "High-level categorization of the definition, used for searching, sorting, and filtering.",
          "valueSet": "http://hl7.org/fhir/ValueSet/definition-topic"
        }
      },
      {
        "id": "Evidence.author",
        "path": "Evidence.author",
        "short": "Who authored the content",
        "definition": "An individiual or organization primarily involved in the creation and maintenance of the content.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.author",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT]"
          }
        ]
      },
      {
        "id": "Evidence.editor",
        "path": "Evidence.editor",
        "short": "Who edited the content",
        "definition": "An individual or organization primarily responsible for internal coherence of the content.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.editor",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Evidence.reviewer",
        "path": "Evidence.reviewer",
        "short": "Who reviewed the content",
        "definition": "An individual or organization primarily responsible for review of some aspect of the content.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.reviewer",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
          }
        ]
      },
      {
        "id": "Evidence.endorser",
        "path": "Evidence.endorser",
        "short": "Who endorsed the content",
        "definition": "An individual or organization responsible for officially endorsing the content for use in some setting.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.endorser",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false,
        "mapping": [
          {
            "identity": "rim",
            "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
          }
        ]
      },
      {
        "id": "Evidence.relatedArtifact",
        "path": "Evidence.relatedArtifact",
        "short": "Additional documentation, citations, etc.",
        "definition": "Related artifacts such as additional documentation, justification, or bibliographic references.",
        "comment": "Each related artifact is either an attachment, or a reference to another resource, but not both.",
        "requirements": "Evidences must be able to provide enough information for consumers of the content (and/or interventions or results produced by the content) to be able to determine and understand the justification for and evidence in support of the content.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Evidence.relatedArtifact",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "RelatedArtifact"
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": false
      },
      {
        "id": "Evidence.exposureBackground",
        "path": "Evidence.exposureBackground",
        "short": "What population?",
        "definition": "A reference to a EvidenceVariable resource that defines the population for the research.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Evidence.exposureBackground",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
            ]
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true
      },
      {
        "id": "Evidence.exposureVariant",
        "path": "Evidence.exposureVariant",
        "short": "What exposure?",
        "definition": "A reference to a EvidenceVariable resource that defines the exposure for the research.",
        "min": 1,
        "max": "2",
        "base": {
          "path": "Evidence.exposureVariant",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
            ]
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true
      },
      {
        "id": "Evidence.outcome",
        "path": "Evidence.outcome",
        "short": "What outcome?",
        "definition": "A reference to a EvidenceVariable resomece that defines the outcome for the research.",
        "min": 1,
        "max": "*",
        "base": {
          "path": "Evidence.outcome",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
            ]
          }
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": false,
        "isSummary": true
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "Evidence",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-display-hint",
            "valueString": "0;0"
          }
        ],
        "path": "Evidence",
        "comment": "PICO stands for Population (the population within which exposures are being compared), Intervention (the conditional state or exposure state being described for its effect on outcomes), Comparison (the alternative conditional state or alternative exposure state being compared against), and Outcome (the result or effect of the intervention in the population).",
        "min": 0,
        "max": "*",
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition"
          }
        ]
      },
      {
        "id": "Evidence.url",
        "path": "Evidence.url",
        "short": "Canonical identifier for this evidence, represented as a URI (globally unique)",
        "definition": "An absolute URI that is used to identify this evidence when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this evidence is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the evidence is stored on different servers.",
        "comment": "Can be a urn:uuid: or a urn:oid: but real http: addresses are preferred.  Multiple instances may share the same URL if they have a distinct version.\n\nThe determination of when to create a new version of a resource (same url, new version) vs. defining a new artifact is up to the author.  Considerations for making this decision are found in [Technical and Business Versions](resource.html#versions). \n\nIn some cases, the resource can no longer be found at the stated url, but the url itself cannot change. Implementations can use the [meta.source](resource.html#meta) element to indicate where the current master source of the resource can be found.",
        "requirements": "Allows the evidence to be referenced by a single globally unique identifier.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "uri"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.url"
          },
          {
            "identity": "w5",
            "map": "FiveWs.identifier"
          }
        ]
      },
      {
        "id": "Evidence.identifier",
        "path": "Evidence.identifier",
        "short": "Additional identifier for the evidence",
        "definition": "A formal identifier that is used to identify this evidence when it is represented in other formats, or referenced in a specification, model, design or an instance.",
        "comment": "Typically, this is used for identifiers that can go in an HL7 V3 II (instance identifier) data type, and can then identify this evidence outside of FHIR, where it is not possible to use the logical URI.",
        "requirements": "Allows externally provided and/or usable business identifiers to be easily associated with the module.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "Identifier"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.identifier"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          },
          {
            "identity": "w5",
            "map": "FiveWs.identifier"
          }
        ]
      },
      {
        "id": "Evidence.version",
        "path": "Evidence.version",
        "short": "Business version of the evidence",
        "definition": "The identifier that is used to identify this version of the evidence when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the evidence author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.",
        "comment": "There may be different evidence instances that have the same identifier but different versions.  The version can be appended to the url in a reference to allow a reference to a particular business version of the evidence with the format [url]|[version].",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "string"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.version"
          },
          {
            "identity": "w5",
            "map": "FiveWs.version"
          }
        ]
      },
      {
        "id": "Evidence.title",
        "path": "Evidence.title",
        "short": "Name for this evidence (human friendly)",
        "definition": "A short, descriptive, user-friendly title for the evidence.",
        "comment": "This name does not need to be machine-processing friendly and may contain punctuation, white-space, etc.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "string"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.title"
          }
        ]
      },
      {
        "id": "Evidence.shortTitle",
        "path": "Evidence.shortTitle",
        "short": "Title for use in informal contexts",
        "definition": "The short title provides an alternate title for use in informal descriptive contexts where the full, formal title is not necessary.",
        "requirements": "Need to be able to reference the content by a short description, but still provide a longer, more formal title for the content.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "string"
          }
        ],
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.title"
          }
        ]
      },
      {
        "id": "Evidence.subtitle",
        "path": "Evidence.subtitle",
        "short": "Subordinate title of the Evidence",
        "definition": "An explanatory or alternate title for the Evidence giving additional information about its content.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "string"
          }
        ]
      },
      {
        "id": "Evidence.status",
        "path": "Evidence.status",
        "short": "draft | active | retired | unknown",
        "definition": "The status of this evidence. Enables tracking the life-cycle of the content.",
        "comment": "Allows filtering of evidences that are appropriate for use versus not.",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "code"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This is labeled as \"Is Modifier\" because applications should not use a retired {{title}} without due consideration",
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "PublicationStatus"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean": true
            }
          ],
          "strength": "required",
          "description": "The lifecycle status of an artifact.",
          "valueSet": "http://hl7.org/fhir/ValueSet/publication-status|4.0.1"
        },
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.status"
          },
          {
            "identity": "w5",
            "map": "FiveWs.status"
          }
        ]
      },
      {
        "id": "Evidence.date",
        "path": "Evidence.date",
        "short": "Date last changed",
        "definition": "The date  (and optionally time) when the evidence was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the evidence changes.",
        "comment": "Note that this is not the same as the resource last-modified-date, since the resource may be a secondary representation of the evidence. Additional specific dates may be added as extensions or be found by consulting Provenances associated with past versions of the resource.",
        "alias": [
          "Revision Date"
        ],
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.date"
          },
          {
            "identity": "w5",
            "map": "FiveWs.recorded"
          }
        ]
      },
      {
        "id": "Evidence.publisher",
        "path": "Evidence.publisher",
        "short": "Name of the publisher (organization or individual)",
        "definition": "The name of the organization or individual that published the evidence.",
        "comment": "Usually an organization but may be an individual. The publisher (or steward) of the evidence is the organization or individual primarily responsible for the maintenance and upkeep of the evidence. This is not necessarily the same individual or organization that developed and initially authored the content. The publisher is the primary point of contact for questions or issues with the evidence. This item SHOULD be populated unless the information is available from context.",
        "requirements": "Helps establish the \"authority/credibility\" of the evidence.  May also allow for contact.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "string"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.publisher"
          },
          {
            "identity": "w5",
            "map": "FiveWs.witness"
          }
        ]
      },
      {
        "id": "Evidence.contact",
        "path": "Evidence.contact",
        "short": "Contact details for the publisher",
        "definition": "Contact details to assist a user in finding and communicating with the publisher.",
        "comment": "May be a web site, an email address, a telephone number, etc.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.contact"
          }
        ]
      },
      {
        "id": "Evidence.description",
        "path": "Evidence.description",
        "short": "Natural language description of the evidence",
        "definition": "A free text natural language description of the evidence from a consumer's perspective.",
        "comment": "This description can be used to capture details such as why the evidence was built, comments about misuse, instructions for clinical use and interpretation, literature references, examples from the paper world, etc. It is not a rendering of the evidence as conveyed in the 'text' field of the resource itself. This item SHOULD be populated unless the information is available from context (e.g. the language of the evidence is presumed to be the predominant language in the place the evidence was created).",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "markdown"
          }
        ],
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.description"
          }
        ]
      },
      {
        "id": "Evidence.note",
        "path": "Evidence.note",
        "short": "Used for footnotes or explanatory notes",
        "definition": "A human-readable string to clarify or explain concepts about the resource.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "Annotation"
          }
        ]
      },
      {
        "id": "Evidence.copyright",
        "path": "Evidence.copyright",
        "short": "Use and/or publishing restrictions",
        "definition": "A copyright statement relating to the evidence and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the evidence.",
        "requirements": "Consumers must be able to determine any legal restrictions on the use of the evidence and/or its content.",
        "alias": [
          "License",
          "Restrictions"
        ],
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "markdown"
          }
        ],
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.copyright"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.approvalDate",
        "path": "Evidence.approvalDate",
        "short": "When the evidence was approved by publisher",
        "definition": "The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage.",
        "comment": "The 'date' element may be more recent than the approval date because of minor changes or editorial corrections.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "date"
          }
        ],
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.approvalDate"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.lastReviewDate",
        "path": "Evidence.lastReviewDate",
        "short": "When the evidence was last reviewed",
        "definition": "The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.",
        "comment": "If specified, this date follows the original approval date.",
        "requirements": "Gives a sense of how \"current\" the content is.  Resources that have not been reviewed in a long time may have a risk of being less appropriate/relevant.",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "date"
          }
        ],
        "mapping": [
          {
            "identity": "workflow",
            "map": "Definition.lastReviewDate"
          },
          {
            "identity": "objimpl",
            "map": "no-gen-base"
          }
        ]
      },
      {
        "id": "Evidence.author",
        "path": "Evidence.author",
        "short": "Who authored the content",
        "definition": "An individiual or organization primarily involved in the creation and maintenance of the content.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT]"
          }
        ]
      },
      {
        "id": "Evidence.editor",
        "path": "Evidence.editor",
        "short": "Who edited the content",
        "definition": "An individual or organization primarily responsible for internal coherence of the content.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "ContactDetail"
          }
        ]
      },
      {
        "id": "Evidence.reviewer",
        "path": "Evidence.reviewer",
        "short": "Who reviewed the content",
        "definition": "An individual or organization primarily responsible for review of some aspect of the content.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "ContactDetail"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": ".participation[typeCode=VRF] {not clear whether VRF best corresponds to reviewer or endorser}"
          }
        ]
      },
      {
        "id": "Evidence.relatedArtifact",
        "path": "Evidence.relatedArtifact",
        "short": "Additional documentation, citations, etc.",
        "definition": "Related artifacts such as additional documentation, justification, or bibliographic references.",
        "comment": "Each related artifact is either an attachment, or a reference to another resource, but not both.",
        "requirements": "Evidences must be able to provide enough information for consumers of the content (and/or interventions or results produced by the content) to be able to determine and understand the justification for and evidence in support of the content.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "RelatedArtifact"
          }
        ]
      },
      {
        "id": "Evidence.exposureBackground",
        "path": "Evidence.exposureBackground",
        "short": "What population?",
        "definition": "A reference to a EvidenceVariable resource that defines the population for the research.",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
            ]
          }
        ]
      },
      {
        "id": "Evidence.exposureVariant",
        "path": "Evidence.exposureVariant",
        "short": "What exposure?",
        "definition": "A reference to a EvidenceVariable resource that defines the exposure for the research.",
        "min": 1,
        "max": "2",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
            ]
          }
        ]
      },
      {
        "id": "Evidence.outcome",
        "path": "Evidence.outcome",
        "short": "What outcome?",
        "definition": "A reference to a EvidenceVariable resomece that defines the outcome for the research.",
        "min": 1,
        "max": "*",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EvidenceVariable"
            ]
          }
        ]
      }
    ]
  }
}

name : Evidence Synthesis Profile

{

}