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<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="pop-pld1-tumor-marker-test" />
  <url value="https://simplifier.net/pop/StructureDefinition/pop-pld1-tumor-marker-test" />
  <version value="0.0.1" />
  <name value="PDL1Tumor Marker Test" />
  <title value="PDL1 Tumor Marker Test" />
  <status value="draft" />
  <date value="2023-09-22T08:15:35.7518841+00:00" />
  <publisher value="Precision Oncology Project (USZ)" />
  <description value="The PD-L1 IHC (Programmed Death-Ligand 1 Immunohistochemical) test is a diagnostic assay utilized in oncology to assess the expression of PD-L1 protein in tissue samples, aiding in treatment decisions, particularly for immunotherapy in cancer patients." />
  <fhirVersion value="4.0.1" />
  <kind value="resource" />
  <abstract value="false" />
  <type value="Observation" />
  <baseDefinition value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tumor-marker-test" />
  <derivation value="constraint" />
  <differential>
    <element id="Observation.extension:antibodyClone">
      <path value="Observation.extension" />
      <sliceName value="antibodyClone" />
      <type>
        <code value="Extension" />
        <profile value="https://simplifier.net/pop/StructureDefinition/pop-antibody-clone" />
      </type>
      <isModifier value="false" />
    </element>
    <element id="Observation.code">
      <path value="Observation.code" />
      <definition value="The test that was performed." />
      <comment value="Fixed." />
      <patternCodeableConcept>
        <coding>
          <system value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl" />
          <code value="C122807" />
        </coding>
      </patternCodeableConcept>
    </element>
    <element id="Observation.method">
      <path value="Observation.method" />
      <patternCodeableConcept>
        <coding>
          <system value="http://snomed.info/sct" />
          <code value="708097004" />
        </coding>
      </patternCodeableConcept>
    </element>
    <element id="Observation.component">
      <path value="Observation.component" />
      <slicing>
        <discriminator>
          <type value="pattern" />
          <path value="$this" />
        </discriminator>
        <rules value="open" />
      </slicing>
    </element>
    <element id="Observation.component:tumor-proportion-score">
      <path value="Observation.component" />
      <sliceName value="tumor-proportion-score" />
      <max value="1" />
    </element>
    <element id="Observation.component:tumor-proportion-score.code">
      <path value="Observation.component.code" />
      <patternCodeableConcept>
        <coding>
          <system value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl" />
          <code value="C184941" />
        </coding>
      </patternCodeableConcept>
    </element>
    <element id="Observation.component:tumor-proportion-score.value[x]">
      <path value="Observation.component.value[x]" />
      <type>
        <code value="Quantity" />
      </type>
      <type>
        <code value="Range" />
      </type>
    </element>
    <element id="Observation.component:tumor-proportion-score.interpretation">
      <path value="Observation.component.interpretation" />
      <binding>
        <strength value="extensible" />
        <valueSet value="https://simplifier.net/pop/ValueSets/pop-pdl1-tumor-cell-scores" />
      </binding>
    </element>
    <element id="Observation.component:immune-cell-score">
      <path value="Observation.component" />
      <sliceName value="immune-cell-score" />
      <max value="1" />
    </element>
    <element id="Observation.component:immune-cell-score.code">
      <path value="Observation.component.code" />
      <patternCodeableConcept>
        <coding>
          <system value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl" />
          <code value="C199175" />
        </coding>
      </patternCodeableConcept>
    </element>
    <element id="Observation.component:immune-cell-score.value[x]">
      <path value="Observation.component.value[x]" />
      <type>
        <code value="Quantity" />
      </type>
      <type>
        <code value="Range" />
      </type>
    </element>
    <element id="Observation.component:immune-cell-score.interpretation">
      <path value="Observation.component.interpretation" />
      <binding>
        <strength value="extensible" />
        <valueSet value="https://simplifier.net/pop/ValueSets/pop-pdl1-immune-cell-scores" />
      </binding>
    </element>
    <element id="Observation.component:combined-positive-score">
      <path value="Observation.component" />
      <sliceName value="combined-positive-score" />
      <max value="1" />
    </element>
    <element id="Observation.component:combined-positive-score.code">
      <path value="Observation.component.code" />
      <patternCodeableConcept>
        <coding>
          <system value="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl" />
          <code value="C176582" />
        </coding>
      </patternCodeableConcept>
    </element>
    <element id="Observation.component:combined-positive-score.value[x]">
      <path value="Observation.component.value[x]" />
      <type>
        <code value="Quantity" />
      </type>
      <type>
        <code value="Range" />
      </type>
    </element>
  </differential>
</StructureDefinition>

name : PDL1Tumor Marker Test

{

}

<name value="PDL1Tumor Marker Test" />