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{
  "resourceType": "StructureDefinition",
  "url": "http://fhir.smart4health.eu/StructureDefinition/s4h-medicationstatement",
  "name": "S4hMedicationStatement",
  "status": "draft",
  "date": "2021-03-09",
  "description": "MedicationStatement profile for the Smart4Health project.",
  "fhirVersion": "4.0.1",
  "mapping": [
    {
      "identity": "workflow",
      "uri": "http://hl7.org/fhir/workflow",
      "name": "Workflow Pattern"
    },
    {
      "identity": "rim",
      "uri": "http://hl7.org/v3",
      "name": "RIM Mapping"
    },
    {
      "identity": "w5",
      "uri": "http://hl7.org/fhir/fivews",
      "name": "FiveWs Pattern Mapping"
    },
    {
      "identity": "v2",
      "uri": "http://hl7.org/v2",
      "name": "HL7 v2 Mapping"
    }
  ],
  "kind": "resource",
  "abstract": false,
  "type": "MedicationStatement",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/MedicationStatement",
  "derivation": "constraint",
  "snapshot": {
    "element": [
      {
        "id": "MedicationStatement",
        "path": "MedicationStatement",
        "short": "Record of medication being taken by a patient",
        "definition": "A record of a medication that is being consumed by a patient.   A MedicationStatement may indicate that the patient may be taking the medication now or has taken the medication in the past or will be taking the medication in the future.  The source of this information can be the patient, significant other (such as a family member or spouse), or a clinician.  A common scenario where this information is captured is during the history taking process during a patient visit or stay.   The medication information may come from sources such as the patient's memory, from a prescription bottle,  or from a list of medications the patient, clinician or other party maintains. \n\nThe primary difference between a medication statement and a medication administration is that the medication administration has complete administration information and is based on actual administration information from the person who administered the medication.  A medication statement is often, if not always, less specific.  There is no required date/time when the medication was administered, in fact we only know that a source has reported the patient is taking this medication, where details such as time, quantity, or rate or even medication product may be incomplete or missing or less precise.  As stated earlier, the medication statement information may come from the patient's memory, from a prescription bottle or from a list of medications the patient, clinician or other party maintains.  Medication administration is more formal and is not missing detailed information.",
        "comment": "When interpreting a medicationStatement, the value of the status and NotTaken needed to be considered:\rMedicationStatement.status + MedicationStatement.wasNotTaken\rStatus=Active + NotTaken=T = Not currently taking\rStatus=Completed + NotTaken=T = Not taken in the past\rStatus=Intended + NotTaken=T = No intention of taking\rStatus=Active + NotTaken=F = Taking, but not as prescribed\rStatus=Active + NotTaken=F = Taking\rStatus=Intended +NotTaken= F = Will be taking (not started)\rStatus=Completed + NotTaken=F = Taken in past\rStatus=In Error + NotTaken=N/A = In Error.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement",
          "min": 0,
          "max": "*"
        },
        "constraint": [
          {
            "key": "dom-2",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
            "expression": "contained.contained.empty()",
            "xpath": "not(parent::f:contained and f:contained)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-4",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
            "expression": "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-3",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
            "expression": "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
            "xpath": "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
                "valueBoolean": true
              },
              {
                "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
                "valueMarkdown": "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
              }
            ],
            "key": "dom-6",
            "severity": "warning",
            "human": "A resource should have narrative for robust management",
            "expression": "text.`div`.exists()",
            "xpath": "exists(f:text/h:div)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-5",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a security label",
            "expression": "contained.meta.security.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:security))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          }
        ],
        "mustSupport": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "workflow",
            "map": "Event"
          },
          {
            "identity": "rim",
            "map": "SubstanceAdministration"
          }
        ]
      },
      {
        "id": "MedicationStatement.id",
        "path": "MedicationStatement.id",
        "short": "Logical id of this artifact",
        "definition": "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
        "comment": "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "isSummary": true
      },
      {
        "id": "MedicationStatement.meta",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.meta",
        "short": "Metadata about the resource",
        "definition": "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.meta",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Meta"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.implicitRules",
        "path": "MedicationStatement.implicitRules",
        "short": "A set of rules under which this content was created",
        "definition": "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
        "comment": "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.implicitRules",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isModifierReason": "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "MedicationStatement.language",
        "path": "MedicationStatement.language",
        "short": "Language of the resource content",
        "definition": "The base language in which the resource is written.",
        "comment": "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.language",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
              "valueCanonical": "http://hl7.org/fhir/ValueSet/all-languages"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Language"
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean": true
            }
          ],
          "strength": "preferred",
          "description": "A human language.",
          "valueSet": "http://hl7.org/fhir/ValueSet/languages"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "MedicationStatement.text",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.text",
        "short": "Text summary of the resource, for human interpretation",
        "definition": "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
        "comment": "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
        "alias": [
          "narrative",
          "html",
          "xhtml",
          "display"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "DomainResource.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Narrative"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act.text?"
          }
        ]
      },
      {
        "id": "MedicationStatement.contained",
        "path": "MedicationStatement.contained",
        "short": "Contained, inline Resources",
        "definition": "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
        "comment": "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
        "alias": [
          "inline resources",
          "anonymous resources",
          "contained resources"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.contained",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Resource"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.modifierExtension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.modifierExtension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Extensions that cannot be ignored",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.identifier",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.identifier",
        "short": "External identifier",
        "definition": "Identifiers associated with this Medication Statement that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server.",
        "comment": "This is a business identifier, not a resource identifier.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.identifier",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Identifier"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CX / EI (occasionally, more often EI maps to a resource id or a URL)"
          },
          {
            "identity": "rim",
            "map": "II - The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs.  Also maps to Role[classCode=IDENT]"
          },
          {
            "identity": "servd",
            "map": "Identifier"
          },
          {
            "identity": "workflow",
            "map": "Event.identifier"
          },
          {
            "identity": "w5",
            "map": "FiveWs.identifier"
          },
          {
            "identity": "rim",
            "map": ".id"
          }
        ]
      },
      {
        "id": "MedicationStatement.basedOn",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.basedOn",
        "short": "Fulfils plan, proposal or order",
        "definition": "A plan, proposal or order that is fulfilled in whole or in part by this event.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "requirements": "Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.basedOn",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/MedicationRequest",
              "http://hl7.org/fhir/StructureDefinition/CarePlan",
              "http://hl7.org/fhir/StructureDefinition/ServiceRequest"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "workflow",
            "map": "Event.basedOn"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=FLFS].target[classCode=SBADM or PROC or PCPR or OBS, moodCode=RQO orPLAN or PRP]"
          }
        ]
      },
      {
        "id": "MedicationStatement.partOf",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.partOf",
        "short": "Part of referenced event",
        "definition": "A larger event of which this particular event is a component or step.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "requirements": "This should not be used when indicating which resource a MedicationStatement has been derived from.  If that is the use case, then MedicationStatement.derivedFrom should be used.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.partOf",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/MedicationAdministration",
              "http://hl7.org/fhir/StructureDefinition/MedicationDispense",
              "http://hl7.org/fhir/StructureDefinition/MedicationStatement",
              "http://hl7.org/fhir/StructureDefinition/Procedure",
              "http://hl7.org/fhir/StructureDefinition/Observation"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "workflow",
            "map": "Event.partOf"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=COMP]/target[classCode=SPLY or SBADM or PROC or OBS,moodCode=EVN]"
          }
        ]
      },
      {
        "id": "MedicationStatement.status",
        "path": "MedicationStatement.status",
        "short": "active | completed | entered-in-error | intended | stopped | on-hold | unknown | not-taken",
        "definition": "A code representing the patient or other source's judgment about the state of the medication used that this statement is about.  Generally, this will be active or completed.",
        "comment": "In the scope of the IPS the entered-in-error concept is not allowed.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "MedicationStatement.status",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isModifier": true,
        "isModifierReason": "This element is labelled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid",
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationStatementStatus"
            }
          ],
          "strength": "required",
          "description": "A coded concept indicating the current status of a MedicationStatement.",
          "valueSet": "http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "workflow",
            "map": "Event.status"
          },
          {
            "identity": "w5",
            "map": "FiveWs.status"
          },
          {
            "identity": "rim",
            "map": ".statusCode"
          }
        ]
      },
      {
        "id": "MedicationStatement.statusReason",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.statusReason",
        "short": "Reason for current status",
        "definition": "Captures the reason for the current state of the MedicationStatement.",
        "comment": "This is generally only used for \"exception\" statuses such as \"not-taken\", \"on-hold\", \"cancelled\" or \"entered-in-error\". The reason for performing the event at all is captured in reasonCode, not here.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.statusReason",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationStatementStatusReason"
            }
          ],
          "strength": "example",
          "description": "A coded concept indicating the reason for the status of the statement.",
          "valueSet": "http://hl7.org/fhir/ValueSet/reason-medication-status-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "workflow",
            "map": "Event.statusReason"
          },
          {
            "identity": "rim",
            "map": ".inboundRelationship[typeCode=SUBJ].source[classCode=CACT, moodCode=EVN].reasonCOde"
          }
        ]
      },
      {
        "id": "MedicationStatement.category",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.category",
        "short": "Type of medication usage",
        "definition": "Indicates where the medication is expected to be consumed or administered.",
        "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "MedicationStatement.category",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationStatementCategory"
            }
          ],
          "strength": "preferred",
          "description": "A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.",
          "valueSet": "http://hl7.org/fhir/ValueSet/medication-statement-category"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "w5",
            "map": "FiveWs.class"
          },
          {
            "identity": "rim",
            "map": ".inboundRelationship[typeCode=COMP].source[classCode=OBS, moodCode=EVN, code=\"type of medication usage\"].value"
          }
        ]
      },
      {
        "id": "MedicationStatement.medication[x]",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.medication[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "closed"
        },
        "short": "What medication was taken",
        "definition": "Identifies the medication being administered or the reason for absent or unknown Medication. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code. To improve global interoperability is strongly encouraged that the reference to a medication resource is used, limiting the usage of the medicationCodeableConcept only to the cases in which no other information than a simple code is available.",
        "comment": "If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended.  For example, if you require form or lot number, then you must reference the Medication resource.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "MedicationStatement.medication[x]",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Medication"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "binding": {
          "strength": "example",
          "description": "The type of medication",
          "valueSet": "http://hl7.org/fhir/uv/ips/ValueSet/medication-example-uv-ips"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "workflow",
            "map": "Event.code"
          },
          {
            "identity": "w5",
            "map": "FiveWs.what[x]"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=CSM].role[classCode=ADMM or MANU]"
          }
        ]
      },
      {
        "id": "MedicationStatement.medication[x]:medicationReference",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.medication[x]",
        "sliceName": "medicationReference",
        "short": "What medication was taken",
        "definition": "Identifies the medication being administered or the reason for absent or unknown Medication. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code. To improve global interoperability is strongly encouraged that the reference to a medication resource is used, limiting the usage of the medicationCodeableConcept only to the cases in which no other information than a simple code is available.",
        "comment": "If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended.  For example, if you require form or lot number, then you must reference the Medication resource.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "MedicationStatement.medication[x]",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/uv/ips/StructureDefinition/Medication-uv-ips"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationCode"
            }
          ],
          "strength": "example",
          "description": "A coded concept identifying the substance or product being taken.",
          "valueSet": "http://hl7.org/fhir/ValueSet/medication-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "workflow",
            "map": "Event.code"
          },
          {
            "identity": "w5",
            "map": "FiveWs.what[x]"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=CSM].role[classCode=ADMM or MANU]"
          }
        ]
      },
      {
        "id": "MedicationStatement.medication[x]:medicationCodeableConcept",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.medication[x]",
        "sliceName": "medicationCodeableConcept",
        "short": "Code for absent or unknown medication",
        "definition": "Code for a negated/excluded medication statement.  This describes a categorical negated statement (e.g., \"No known medications\").",
        "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "MedicationStatement.medication[x]",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept",
            "profile": [
              "http://hl7.org/fhir/uv/ips/StructureDefinition/CodeableConcept-uv-ips"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "binding": {
          "strength": "extensible",
          "description": "Representation of unknown or absent medications",
          "valueSet": "http://hl7.org/fhir/uv/ips/ValueSet/absent-or-unknown-medications-uv-ips"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "workflow",
            "map": "Event.code"
          },
          {
            "identity": "w5",
            "map": "FiveWs.what[x]"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=CSM].role[classCode=ADMM or MANU]"
          }
        ]
      },
      {
        "id": "MedicationStatement.subject",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.subject",
        "short": "Who is/was taking  the medication",
        "definition": "The person, animal or group who is/was taking the medication.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "MedicationStatement.subject",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://fhir.smart4health.eu/StructureDefinition/s4h-patient"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "workflow",
            "map": "Event.subject"
          },
          {
            "identity": "w5",
            "map": "FiveWs.subject[x]"
          },
          {
            "identity": "v2",
            "map": "PID-3-Patient ID List"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=SBJ].role[classCode=PAT]"
          },
          {
            "identity": "w5",
            "map": "FiveWs.subject"
          }
        ]
      },
      {
        "id": "MedicationStatement.context",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.context",
        "short": "Encounter / Episode associated with MedicationStatement",
        "definition": "The encounter or episode of care that establishes the context for this MedicationStatement.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "MedicationStatement.context",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EpisodeOfCare",
              "http://fhir.smart4health.eu/StructureDefinition/s4h-encounter"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "workflow",
            "map": "Event.context"
          },
          {
            "identity": "rim",
            "map": ".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN, code=\"type of encounter or episode\"]"
          }
        ]
      },
      {
        "id": "MedicationStatement.effective[x]",
        "path": "MedicationStatement.effective[x]",
        "short": "The date/time or interval when the medication is/was/will be taken",
        "definition": "The interval of time during which it is being asserted that the patient is/was/will be taking the medication (or was not taking, when the MedicationStatement.taken element is No).",
        "comment": "This attribute reflects the period over which the patient consumed the medication and is expected to be populated on the majority of Medication Statements. If the medication is still being taken at the time the statement is recorded, the \"end\" date will be omitted.  The date/time attribute supports a variety of dates - year, year/month and exact date.  If something more than this is required, this should be conveyed as text.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "MedicationStatement.effective[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          },
          {
            "code": "Period"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "workflow",
            "map": "Event.occurrence[x]"
          },
          {
            "identity": "w5",
            "map": "FiveWs.done[x]"
          },
          {
            "identity": "rim",
            "map": ".effectiveTime"
          }
        ]
      },
      {
        "id": "MedicationStatement.dateAsserted",
        "path": "MedicationStatement.dateAsserted",
        "short": "When the statement was asserted?",
        "definition": "The date when the medication statement was asserted by the information source.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "MedicationStatement.dateAsserted",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "w5",
            "map": "FiveWs.recorded"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT].time"
          }
        ]
      },
      {
        "id": "MedicationStatement.informationSource",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.informationSource",
        "short": "Person or organization that provided the information about the taking of this medication",
        "definition": "The person or organization that provided the information about the taking of this medication. Note: Use derivedFrom when a MedicationStatement is derived from other resources, e.g. Claim or MedicationRequest.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "MedicationStatement.informationSource",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient",
              "http://hl7.org/fhir/StructureDefinition/Practitioner",
              "http://hl7.org/fhir/StructureDefinition/PractitionerRole",
              "http://hl7.org/fhir/StructureDefinition/RelatedPerson",
              "http://hl7.org/fhir/StructureDefinition/Organization"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "mustSupport": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "w5",
            "map": "FiveWs.source"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=INF].role[classCode=PAT, or codes for Practioner or Related Person (if PAT is the informer, then syntax for self-reported =true)"
          }
        ]
      },
      {
        "id": "MedicationStatement.derivedFrom",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.derivedFrom",
        "short": "Additional supporting information",
        "definition": "Allows linking the MedicationStatement to the underlying MedicationRequest, or to other information that supports or is used to derive the MedicationStatement.",
        "comment": "Likely references would be to MedicationRequest, MedicationDispense, Claim, Observation or QuestionnaireAnswers.  The most common use cases for deriving a MedicationStatement comes from creating a MedicationStatement from a MedicationRequest or from a lab observation or a claim.  it should be noted that the amount of information that is available varies from the type resource that you derive the MedicationStatement from.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.derivedFrom",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Resource"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=SPRT]/target[classCode=ACT,moodCode=EVN]"
          }
        ]
      },
      {
        "id": "MedicationStatement.reasonCode",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.reasonCode",
        "short": "Reason for why the medication is being/was taken",
        "definition": "A reason for why the medication is being/was taken.",
        "comment": "This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.reasonCode",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationReason"
            }
          ],
          "strength": "example",
          "description": "A coded concept identifying why the medication is being taken.",
          "valueSet": "http://hl7.org/fhir/ValueSet/condition-code"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "workflow",
            "map": "Event.reasonCode"
          },
          {
            "identity": "w5",
            "map": "FiveWs.why[x]"
          },
          {
            "identity": "rim",
            "map": ".reasonCode"
          }
        ]
      },
      {
        "id": "MedicationStatement.reasonReference",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.reasonReference",
        "short": "Condition or observation that supports why the medication is being/was taken",
        "definition": "Condition or observation that supports why the medication is being/was taken.",
        "comment": "This is a reference to a condition that is the reason why the medication is being/was taken.  If only a code exists, use reasonForUseCode.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.reasonReference",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Condition",
              "http://hl7.org/fhir/StructureDefinition/Observation",
              "http://hl7.org/fhir/StructureDefinition/DiagnosticReport"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Condition"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "workflow",
            "map": "Event.reasonReference"
          },
          {
            "identity": "w5",
            "map": "FiveWs.why[x]"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=RSON]/target[classCode=OBS,moodCode=EVN, code=\"reason for use\"].value"
          }
        ]
      },
      {
        "id": "MedicationStatement.note",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.note",
        "short": "Further information about the statement",
        "definition": "Provides extra information about the medication statement that is not conveyed by the other attributes.",
        "comment": "For systems that do not have structured annotations, they can simply communicate a single annotation with no author or time.  This element may need to be included in narrative because of the potential for modifying information.  *Annotations SHOULD NOT* be used to communicate \"modifying\" information that could be computable. (This is a SHOULD because enforcing user behavior is nearly impossible).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.note",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act"
          },
          {
            "identity": "workflow",
            "map": "Event.note"
          },
          {
            "identity": "rim",
            "map": ".inboundRelationship[typeCode=SUBJ]/source[classCode=OBS,moodCode=EVN,code=\"annotation\"].value"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "trial-use"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage",
        "short": "Details of how medication is/was taken or should be taken",
        "definition": "Indicates how the medication is/was or should be taken by the patient.",
        "comment": "The dates included in the dosage on a Medication Statement reflect the dates for a given dose.  For example, \"from November 1, 2016 to November 3, 2016, take one tablet daily and from November 4, 2016 to November 7, 2016, take two tablets daily.\"  It is expected that this specificity may only be populated where the patient brings in their labeled container or where the Medication Statement is derived from a MedicationRequest.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "MedicationStatement.dosage",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Dosage"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT]"
          },
          {
            "identity": "rim",
            "map": "refer dosageInstruction mapping"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.id",
        "path": "MedicationStatement.dosage.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.modifierExtension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.modifierExtension",
        "short": "Extensions that cannot be ignored even if unrecognized",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias": [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "BackboneElement.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          }
        ],
        "isModifier": true,
        "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.sequence",
        "path": "MedicationStatement.dosage.sequence",
        "short": "The order of the dosage instructions",
        "definition": "Indicates the order in which the dosage instructions should be applied or interpreted.",
        "comment": "32 bit number; for values larger than this, use decimal",
        "requirements": "If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent.  If the sequence number is different, then the Dosages are intended to be sequential.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.sequence",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "integer"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-1"
          },
          {
            "identity": "rim",
            "map": ".text"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.text",
        "path": "MedicationStatement.dosage.text",
        "short": "Free text dosage instructions e.g. SIG",
        "definition": "Free text dosage instructions e.g. SIG.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "requirements": "Free text dosage instructions can be used for cases where the instructions are too complex to code.  The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated.  If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing.  Additional information about administration or preparation of the medication should be included as text.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-6; RXE-21"
          },
          {
            "identity": "rim",
            "map": ".text"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.additionalInstruction",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.additionalInstruction",
        "short": "Supplemental instruction or warnings to the patient - e.g. \"with meals\", \"may cause drowsiness\"",
        "definition": "Supplemental instructions to the patient on how to take the medication  (e.g. \"with meals\" or\"take half to one hour before food\") or warnings for the patient about the medication (e.g. \"may cause drowsiness\" or \"avoid exposure of skin to direct sunlight or sunlamps\").",
        "comment": "Information about administration or preparation of the medication (e.g. \"infuse as rapidly as possibly via intraperitoneal port\" or \"immediately following drug x\") should be populated in dosage.text.",
        "requirements": "Additional instruction is intended to be coded, but where no code exists, the element could include text.  For example, \"Swallow with plenty of water\" which might or might not be coded.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Dosage.additionalInstruction",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AdditionalInstruction"
            }
          ],
          "strength": "example",
          "description": "A coded concept identifying additional instructions such as \"take with water\" or \"avoid operating heavy machinery\".",
          "valueSet": "http://hl7.org/fhir/ValueSet/additional-instruction-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXO-7"
          },
          {
            "identity": "rim",
            "map": ".text"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.patientInstruction",
        "path": "MedicationStatement.dosage.patientInstruction",
        "short": "Patient or consumer oriented instructions",
        "definition": "Instructions in terms that are understood by the patient or consumer.",
        "comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.patientInstruction",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "RXO-7"
          },
          {
            "identity": "rim",
            "map": ".text"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.timing",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.timing",
        "short": "When medication should be administered",
        "definition": "When medication should be administered.",
        "comment": "This attribute might not always be populated while the Dosage.text is expected to be populated.  If both are populated, then the Dosage.text should reflect the content of the Dosage.timing.",
        "requirements": "The timing schedule for giving the medication to the patient. This  data type allows many different expressions. For example: \"Every 8 hours\"; \"Three times a day\"; \"1/2 an hour before breakfast for 10 days from 23-Dec 2011:\"; \"15 Oct 2013, 17 Oct 2013 and 1 Nov 2013\".  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.timing",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Timing"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "QSET<TS> (GTS)"
          },
          {
            "identity": "rim",
            "map": ".effectiveTime"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.asNeeded[x]",
        "path": "MedicationStatement.dosage.asNeeded[x]",
        "short": "Take \"as needed\" (for x)",
        "definition": "Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept).",
        "comment": "Can express \"as needed\" without a reason by setting the Boolean = True.  In this case the CodeableConcept is not populated.  Or you can express \"as needed\" with a reason by including the CodeableConcept.  In this case the Boolean is assumed to be True.  If you set the Boolean to False, then the dose is given according to the schedule and is not \"prn\" or \"as needed\".",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.asNeeded[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "boolean"
          },
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAsNeededReason"
            }
          ],
          "strength": "example",
          "description": "A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose.  For example \"pain\", \"30 minutes prior to sexual intercourse\", \"on flare-up\" etc.",
          "valueSet": "http://hl7.org/fhir/ValueSet/medication-as-needed-reason"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-9"
          },
          {
            "identity": "rim",
            "map": ".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=\"as needed\"].value=boolean or codable concept"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.site",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.site",
        "short": "Body site to administer to",
        "definition": "Body site to administer to.",
        "comment": "If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension [bodySite](extension-bodysite.html).  May be a summary code, or a reference to a very precise definition of the location, or both.",
        "requirements": "A coded specification of the anatomic site where the medication first enters the body.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.site",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAdministrationSite"
            }
          ],
          "strength": "example",
          "description": "A coded concept describing the site location the medicine enters into or onto the body.",
          "valueSet": "http://hl7.org/fhir/ValueSet/approach-site-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXR-2"
          },
          {
            "identity": "rim",
            "map": ".approachSiteCode"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.route",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.route",
        "short": "Concept - reference to a terminology or just  text",
        "definition": "A concept that may be defined by a formal reference to a terminology or ontology or may be provided by text.",
        "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.",
        "requirements": "A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.route",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept",
            "profile": [
              "http://hl7.org/fhir/uv/ips/StructureDefinition/CodeableConcept-uv-ips"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mustSupport": true,
        "isSummary": true,
        "binding": {
          "strength": "preferred",
          "description": "EDQM Standards Terms",
          "valueSet": "http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXR-1"
          },
          {
            "identity": "rim",
            "map": ".routeCode"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.method",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.method",
        "short": "Technique for administering medication",
        "definition": "Technique for administering medication.",
        "comment": "Terminologies used often pre-coordinate this term with the route and or form of administration.",
        "requirements": "A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections.  For examples, Slow Push; Deep IV.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.method",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "MedicationAdministrationMethod"
            }
          ],
          "strength": "example",
          "description": "A coded concept describing the technique by which the medicine is administered.",
          "valueSet": "http://hl7.org/fhir/ValueSet/administration-method-codes"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXR-4"
          },
          {
            "identity": "rim",
            "map": ".doseQuantity"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.doseAndRate",
        "path": "MedicationStatement.dosage.doseAndRate",
        "short": "Amount of medication administered",
        "definition": "The amount of medication administered.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "Dosage.doseAndRate",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Element"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "TQ1-2"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.doseAndRate.id",
        "path": "MedicationStatement.dosage.doseAndRate.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "Unique id for inter-element referencing",
        "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
                "valueUrl": "string"
              }
            ],
            "code": "http://hl7.org/fhirpath/System.String"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.doseAndRate.extension",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.doseAndRate.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.doseAndRate.type",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.doseAndRate.type",
        "short": "The kind of dose or rate specified",
        "definition": "The kind of dose or rate specified, for example, ordered or calculated.",
        "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.",
        "requirements": "If the type is not populated, assume to be \"ordered\".",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.type",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "DoseAndRateType"
            }
          ],
          "strength": "example",
          "description": "The kind of dose or rate specified.",
          "valueSet": "http://hl7.org/fhir/ValueSet/dose-rate-type"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "RXO-21; RXE-23"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.doseAndRate.dose[x]",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.doseAndRate.dose[x]",
        "short": "Amount of medication per dose",
        "definition": "Amount of medication per dose.",
        "comment": "Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.",
        "requirements": "The amount of therapeutic or other substance given at one administration event.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.dose[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Range"
          },
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "rng-2",
            "severity": "error",
            "human": "If present, low SHALL have a lower value than high",
            "expression": "low.empty() or high.empty() or (low <= high)",
            "xpath": "not(exists(f:low/f:value/@value)) or not(exists(f:high/f:value/@value)) or (number(f:low/f:value/@value) <= number(f:high/f:value/@value))",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "NR and also possibly SN (but see also quantity)"
          },
          {
            "identity": "rim",
            "map": "IVL<QTY[not(type=\"TS\")]> [lowClosed=\"true\" and highClosed=\"true\"]or URG<QTY[not(type=\"TS\")]>"
          },
          {
            "identity": "v2",
            "map": "RXO-2, RXE-3"
          },
          {
            "identity": "rim",
            "map": ".doseQuantity"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.doseAndRate.rate[x]",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.doseAndRate.rate[x]",
        "short": "Amount of medication per unit of time",
        "definition": "Amount of medication per unit of time.",
        "comment": "It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.\r\rIt is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.",
        "requirements": "Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.doseAndRate.rate[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Ratio"
          },
          {
            "code": "Range"
          },
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "rat-1",
            "severity": "error",
            "human": "Numerator and denominator SHALL both be present, or both are absent. If both are absent, there SHALL be some extension present",
            "expression": "(numerator.empty() xor denominator.exists()) and (numerator.exists() or extension.exists())",
            "xpath": "(count(f:numerator) = count(f:denominator)) and ((count(f:numerator) > 0) or (count(f:extension) > 0))",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "RTO"
          },
          {
            "identity": "v2",
            "map": "RXE22, RXE23, RXE-24"
          },
          {
            "identity": "rim",
            "map": ".rateQuantity"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.maxDosePerPeriod",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.maxDosePerPeriod",
        "short": "Upper limit on medication per unit of time",
        "definition": "Upper limit on medication per unit of time.",
        "comment": "This is intended for use as an adjunct to the dosage when there is an upper cap.  For example \"2 tablets every 4 hours to a maximum of 8/day\".",
        "requirements": "The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time.  For example, 1000mg in 24 hours.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.maxDosePerPeriod",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Ratio"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "rat-1",
            "severity": "error",
            "human": "Numerator and denominator SHALL both be present, or both are absent. If both are absent, there SHALL be some extension present",
            "expression": "(numerator.empty() xor denominator.exists()) and (numerator.exists() or extension.exists())",
            "xpath": "(count(f:numerator) = count(f:denominator)) and ((count(f:numerator) > 0) or (count(f:extension) > 0))",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "RTO"
          },
          {
            "identity": "v2",
            "map": "RXO-23, RXE-19"
          },
          {
            "identity": "rim",
            "map": ".maxDoseQuantity"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.maxDosePerAdministration",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.maxDosePerAdministration",
        "short": "Upper limit on medication per administration",
        "definition": "Upper limit on medication per administration.",
        "comment": "This is intended for use as an adjunct to the dosage when there is an upper cap.  For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg.",
        "requirements": "The maximum total quantity of a therapeutic substance that may be administered to a subject per administration.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.maxDosePerAdministration",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "rim",
            "map": "not supported"
          }
        ]
      },
      {
        "id": "MedicationStatement.dosage.maxDosePerLifetime",
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
            "valueCode": "normative"
          },
          {
            "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
            "valueCode": "4.0.0"
          }
        ],
        "path": "MedicationStatement.dosage.maxDosePerLifetime",
        "short": "Upper limit on medication per lifetime of the patient",
        "definition": "Upper limit on medication per lifetime of the patient.",
        "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.",
        "requirements": "The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Dosage.maxDosePerLifetime",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Quantity",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/SimpleQuantity"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() or (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "qty-3",
            "severity": "error",
            "human": "If a code for the unit is present, the system SHALL also be present",
            "expression": "code.empty() or system.exists()",
            "xpath": "not(exists(f:code)) or exists(f:system)",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          },
          {
            "key": "sqty-1",
            "severity": "error",
            "human": "The comparator is not used on a SimpleQuantity",
            "expression": "comparator.empty()",
            "xpath": "not(exists(f:comparator))",
            "source": "http://hl7.org/fhir/StructureDefinition/Dosage"
          }
        ],
        "isModifier": false,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "SN (see also Range) or CQ"
          },
          {
            "identity": "rim",
            "map": "PQ, IVL<PQ>, MO, CO, depending on the values"
          },
          {
            "identity": "rim",
            "map": "not supported"
          }
        ]
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "MedicationStatement",
        "path": "MedicationStatement",
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.status",
        "path": "MedicationStatement.status",
        "comment": "In the scope of the IPS the entered-in-error concept is not allowed.",
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.medication[x]",
        "path": "MedicationStatement.medication[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "closed"
        },
        "definition": "Identifies the medication being administered or the reason for absent or unknown Medication. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code. To improve global interoperability is strongly encouraged that the reference to a medication resource is used, limiting the usage of the medicationCodeableConcept only to the cases in which no other information than a simple code is available.",
        "mustSupport": true,
        "binding": {
          "strength": "example",
          "description": "The type of medication",
          "valueSet": "http://hl7.org/fhir/uv/ips/ValueSet/medication-example-uv-ips"
        }
      },
      {
        "id": "MedicationStatement.medication[x]:medicationReference",
        "path": "MedicationStatement.medication[x]",
        "sliceName": "medicationReference",
        "definition": "Identifies the medication being administered or the reason for absent or unknown Medication. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code. To improve global interoperability is strongly encouraged that the reference to a medication resource is used, limiting the usage of the medicationCodeableConcept only to the cases in which no other information than a simple code is available.",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/uv/ips/StructureDefinition/Medication-uv-ips"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.medication[x]:medicationCodeableConcept",
        "path": "MedicationStatement.medication[x]",
        "sliceName": "medicationCodeableConcept",
        "short": "Code for absent or unknown medication",
        "definition": "Code for a negated/excluded medication statement.  This describes a categorical negated statement (e.g., \"No known medications\").",
        "type": [
          {
            "code": "CodeableConcept",
            "profile": [
              "http://hl7.org/fhir/uv/ips/StructureDefinition/CodeableConcept-uv-ips"
            ]
          }
        ],
        "binding": {
          "strength": "extensible",
          "description": "Representation of unknown or absent medications",
          "valueSet": "http://hl7.org/fhir/uv/ips/ValueSet/absent-or-unknown-medications-uv-ips"
        }
      },
      {
        "id": "MedicationStatement.subject",
        "path": "MedicationStatement.subject",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://fhir.smart4health.eu/StructureDefinition/s4h-patient"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.context",
        "path": "MedicationStatement.context",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/EpisodeOfCare",
              "http://fhir.smart4health.eu/StructureDefinition/s4h-encounter"
            ]
          }
        ]
      },
      {
        "id": "MedicationStatement.effective[x]",
        "path": "MedicationStatement.effective[x]",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.informationSource",
        "path": "MedicationStatement.informationSource",
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.dosage",
        "path": "MedicationStatement.dosage",
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.dosage.text",
        "path": "MedicationStatement.dosage.text",
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.dosage.timing",
        "path": "MedicationStatement.dosage.timing",
        "mustSupport": true
      },
      {
        "id": "MedicationStatement.dosage.route",
        "path": "MedicationStatement.dosage.route",
        "type": [
          {
            "code": "CodeableConcept",
            "profile": [
              "http://hl7.org/fhir/uv/ips/StructureDefinition/CodeableConcept-uv-ips"
            ]
          }
        ],
        "binding": {
          "strength": "preferred",
          "description": "EDQM Standards Terms",
          "valueSet": "http://hl7.org/fhir/uv/ips/ValueSet/medicine-route-of-administration"
        }
      }
    ]
  }
}

name : S4hMedicationStatement

{

}