{
  "resourceType": "StructureDefinition",
  "id": "VariantCallFormat",
  "url": "http://hl7.org/fhir/StructureDefinition/VCF",
  "name": "VariantCallFormat",
  "title": "Variant Call Format",
  "status": "draft",
  "purpose": "A logical model of the Variant Call Format model, specifying the format text files used in bioinformatics for storing gene sequence variations.",
  "fhirVersion": "3.0.2",
  "kind": "logical",
  "abstract": false,
  "type": "VCF",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Element",
  "derivation": "specialization",
  "differential": {
    "element": [
      {
        "id": "VCF",
        "path": "VCF",
        "definition": "VCF (root element)",
        "min": 0,
        "max": "1"
      },
      {
        "id": "VCF.Header",
        "path": "VCF.Header",
        "definition": "Container for the metainfo of the file",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.fileformat",
        "path": "VCF.Header.fileformat",
        "definition": "The format of the file and the version number. \r\nShould be given in the following format: \"VCFv4.1\"",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.contig",
        "path": "VCF.Header.contig",
        "definition": "A contiguousset of overlapping DNA segments that represent a consensus region of DNA. \r\nA list of IDs for the DNA sequences that appear in the reference genome.",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.contig.ID",
        "path": "VCF.Header.contig.ID",
        "definition": "Identification tag for the contig segment",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "id",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/id"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.contig.Optional",
        "path": "VCF.Header.contig.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.contig.Optional.Name",
        "path": "VCF.Header.contig.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.contig.Optional.Value",
        "path": "VCF.Header.contig.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.INFO",
        "path": "VCF.Header.INFO",
        "definition": "The info field should be described as follows: ##INFO=<ID=ID, Number=number, Type=type, Description=\"description\">",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.INFO.ID",
        "path": "VCF.Header.INFO.ID",
        "definition": "ID given to the instance",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "id",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/id"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.INFO.Number",
        "path": "VCF.Header.INFO.Number",
        "definition": "Number describes the number of values that can be included in the info field",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "integer",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/integer"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.INFO.Type",
        "path": "VCF.Header.INFO.Type",
        "definition": "Type describes the datatype of the field",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.INFO.Description",
        "path": "VCF.Header.INFO.Description",
        "definition": "Description of the ID",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.INFO.Optional",
        "path": "VCF.Header.INFO.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.INFO.Optional.Name",
        "path": "VCF.Header.INFO.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.INFO.Optional.Value",
        "path": "VCF.Header.INFO.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.FILTER",
        "path": "VCF.Header.FILTER",
        "definition": "Filters that have been applied to the data.\r\n##FILTER=<ID=ID, Description=\"description\">",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FILTER.ID",
        "path": "VCF.Header.FILTER.ID",
        "definition": "ID given to the instance",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "id",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/id"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FILTER.Description",
        "path": "VCF.Header.FILTER.Description",
        "definition": "Description of the ID",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FILTER.Optional",
        "path": "VCF.Header.FILTER.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.FILTER.Optional.Name",
        "path": "VCF.Header.FILTER.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.FILTER.Optional.Value",
        "path": "VCF.Header.FILTER.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.FORMAT",
        "path": "VCF.Header.FORMAT",
        "definition": "Format of the file",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FORMAT.ID",
        "path": "VCF.Header.FORMAT.ID",
        "comment": "ID given to the instance",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "id",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/id"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FORMAT.Number",
        "path": "VCF.Header.FORMAT.Number",
        "definition": "Number describes the number of values that can be included in the format field",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "integer",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/integer"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FORMAT.Type",
        "path": "VCF.Header.FORMAT.Type",
        "definition": "Type describes the datatype of the field",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FORMAT.Description",
        "path": "VCF.Header.FORMAT.Description",
        "comment": "Description of the ID",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.FORMAT.Optional",
        "path": "VCF.Header.FORMAT.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.FORMAT.Optional.Name",
        "path": "VCF.Header.FORMAT.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.FORMAT.Optional.Value",
        "path": "VCF.Header.FORMAT.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.ALT",
        "path": "VCF.Header.ALT",
        "definition": "Filters that have been applied to the data.\r\n##FILTER=<ID=ID, Description=\"description\">",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.ALT.ID",
        "path": "VCF.Header.ALT.ID",
        "definition": "ID given to the instance",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "id",
            "profile": [
              "http://hl7.org/fhir/StructureDefinitions/id"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.ALT.Description",
        "path": "VCF.Header.ALT.Description",
        "definition": "Description of the ID",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Header.ALT.Optional",
        "path": "VCF.Header.ALT.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.ALT.Optional.Name",
        "path": "VCF.Header.ALT.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.ALT.Optional.Value",
        "path": "VCF.Header.ALT.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.OPTIONAL",
        "path": "VCF.Header.OPTIONAL",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.OPTIONAL.Name",
        "path": "VCF.Header.OPTIONAL.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.OPTIONAL.Value",
        "path": "VCF.Header.OPTIONAL.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.PEDIGREE",
        "path": "VCF.Header.PEDIGREE",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.PEDIGREE.Optional",
        "path": "VCF.Header.PEDIGREE.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.PEDIGREE.Optional.Name",
        "path": "VCF.Header.PEDIGREE.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.PEDIGREE.Optional.Value",
        "path": "VCF.Header.PEDIGREE.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.pedigreeDB",
        "path": "VCF.Header.pedigreeDB",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.pedigreeDB.url",
        "path": "VCF.Header.pedigreeDB.url",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE",
        "path": "VCF.Header.SAMPLE",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.ID",
        "path": "VCF.Header.SAMPLE.ID",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.Genomes",
        "path": "VCF.Header.SAMPLE.Genomes",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.Mixture",
        "path": "VCF.Header.SAMPLE.Mixture",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.Description",
        "path": "VCF.Header.SAMPLE.Description",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.Optional",
        "path": "VCF.Header.SAMPLE.Optional",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.Optional.Name",
        "path": "VCF.Header.SAMPLE.Optional.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Header.SAMPLE.Optional.Value",
        "path": "VCF.Header.SAMPLE.Optional.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Body",
        "path": "VCF.Body",
        "definition": "Content of the file",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records",
        "path": "VCF.Body.Records",
        "min": 1,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": false
      },
      {
        "id": "VCF.Body.Records.CHROM",
        "path": "VCF.Body.Records.CHROM",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "CodeableConcept",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/CodeableConcept"
            ]
          }
        ],
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "valueSetUri": "http://hl7.org/fhir/ValueSet/chromosome-human"
        }
      },
      {
        "id": "VCF.Body.Records.POS",
        "path": "VCF.Body.Records.POS",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.ID",
        "path": "VCF.Body.Records.ID",
        "min": 1,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.REF",
        "path": "VCF.Body.Records.REF",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.ALT",
        "path": "VCF.Body.Records.ALT",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.QUAL",
        "path": "VCF.Body.Records.QUAL",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.FILTER",
        "path": "VCF.Body.Records.FILTER",
        "min": 1,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.INFO",
        "path": "VCF.Body.Records.INFO",
        "min": 1,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.FORMAT",
        "path": "VCF.Body.Records.FORMAT",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.SAMPLE",
        "path": "VCF.Body.Records.SAMPLE",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "VCF.Body.Records.SAMPLE.Name",
        "path": "VCF.Body.Records.SAMPLE.Name",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      },
      {
        "id": "VCF.Body.Records.SAMPLE.Value",
        "path": "VCF.Body.Records.SAMPLE.Value",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "string",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/string"
            ]
          }
        ]
      }
    ]
  }
}