<status value="draft" /> <date value="2020-09-17T11:33:08.6995668+00:00" /> <purpose value="Classificatin of substances" /> <fhirVersion value="4.0.1" /> <mapping> <identity value="rim" /> <uri value="http://hl7.org/v3" /> <name value="RIM Mapping" /> </mapping> <kind value="complex-type" /> <abstract value="false" /> <context> <type value="element" /> <expression value="SubstanceSpecification" /> </context> <type value="Extension" /> <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Extension" /> <derivation value="constraint" /> <snapshot> <element id="Extension"> <path value="Extension" /> <short value="Classifies the substance" /> <definition value="Optional xtension for classifying substances. Possible classification categories: - All the substance's ATC code(s). One entry per code. - The substance's E-number(s). One entry per e-number. - Whether the substance is therapeutic (only published when "true") - Whether the substance is a prodrug (only published when "true") - Whether the substance is complex (only published when "true")" /> <comment value="##### Published (optional) classification categories: ###### **E-Number** The substance's [E-number(s)](https://ec.europa.eu/food/food-feed-portal/screen/food-additives/search). A substance can have multiple e-numbers. Cardinality: 0..* Code: The E-number Display: The E-number name (substance) System URL: [https://mpd.noma.no/codesystem/e-number](https://mpd.noma.no/codesystem/e-number) ###### **Is Therapeutic** Whether the substance is therapeutic (only published when "true"). Cardinality: 0..1 Code: "true" Display: "Er terapautisk del" System URL: [https://mpd.noma.no/codesystem/is-active-moiety](https://mpd.noma.no/codesystem/is-active-moiety) ###### **Is Prodrug** Whether the substance is a prodrug (only published when "true") Cardinality: 0..1 Code: "true" Display: "Er prodrug" System URL: [https://mpd.noma.no/codesystem/is-prodrug](https://mpd.noma.no/codesystem/is-prodrug) ###### **Is Complex** Whether the substance is complex (only published when "true") Cardinality: 0..1 Code: "true" Display: "Er kompleks" System URL: [https://mpd.noma.no/codesystem/is-complex-substance](https://mpd.noma.no/codesystem/is-complex-substance) ###### **ATC codes** All the substance's ATC code(s). Human codes only. Cardinality: 0..* Code: The ATC code Display: The (substances) name System URLs, one per first-level ATC: | ATC Category Name | Source | URL (GUPRI) | | :------- | :------ |:------ | | ATC (A) Alimentary tract and metabolism | WHO | [https://mpd.noma.no/codesystem/atc-a-alimentary-tract-and-metabolism](https://mpd.noma.no/codesystem/atc-a-alimentary-tract-and-metabolism) | | ATC (J) Antiinfectives | WHO | [https://mpd.noma.no/codesystem/atc-j-antiinfectives-for-systemic-use](https://mpd.noma.no/codesystem/atc-j-antiinfectives-for-systemic-use) | | ATC (L) Antineoplastic, immunomodulating agents | WHO | [https://mpd.noma.no/codesystem/atc-l-antineoplastic-and-immunomodulating-agents](https://mpd.noma.no/codesystem/atc-l-antineoplastic-and-immunomodulating-agents) | | ATC (P) Antiparasitic Products | WHO | [https://mpd.noma.no/codesystem/atc-p-antiparasitic-products-insecticides-and-repellents](https://mpd.noma.no/codesystem/atc-p-antiparasitic-products-insecticides-and-repellents) | | ATC (B) Blood, Blood Forming Organs | WHO | [https://mpd.noma.no/codesystem/atc-b-blood-and-blood-forming-organs](https://mpd.noma.no/codesystem/atc-b-blood-and-blood-forming-organs) | | ATC (C) Cardiovascular System | WHO | [https://mpd.noma.no/codesystem/atc-c-cardiovascular-system](https://mpd.noma.no/codesystem/atc-c-cardiovascular-system) | | ATC (D) Dermatologicals | WHO | [https://mpd.noma.no/codesystem/atc-d-dermatologicals](https://mpd.noma.no/codesystem/atc-d-dermatologicals) | | ATC (G) Genito urinary System | WHO | [https://mpd.noma.no/codesystem/atc-g-genito-urinary-system-and-sex-hormones](https://mpd.noma.no/codesystem/atc-g-genito-urinary-system-and-sex-hormones) | | ATC (M) Musculo-skeletal System | WHO | [https://mpd.noma.no/codesystem/atc-m-musculo-skeletal-system](https://mpd.noma.no/codesystem/atc-m-musculo-skeletal-system) | | ATC (N) Nervous system | WHO | [https://mpd.noma.no/codesystem/atc-n-nervous-system](https://mpd.noma.no/codesystem/atc-n-nervous-system) | | ATC (R) Respiratory System | WHO | [https://mpd.noma.no/codesystem/atc-r-respiratory-system](https://mpd.noma.no/codesystem/atc-r-respiratory-system) | | ATC (S) Sensory Organs | WHO | [https://mpd.noma.no/codesystem/atc-s-sensory-organs](https://mpd.noma.no/codesystem/atc-s-sensory-organs) | | ATC (H) Systemic Hormonal Preparations | WHO | [https://mpd.noma.no/codesystem/atc-h-systemic-hormonal-preparations-excl-sex-hormones-and-insulins](https://mpd.noma.no/codesystem/atc-h-systemic-hormonal-preparations-excl-sex-hormones-and-insulins) | | ATC (V) Various | WHO | [https://mpd.noma.no/codesystem/atc-v-various](https://mpd.noma.no/codesystem/atc-v-various) |" /> <min value="0" /> <max value="*" /> <base> <path value="Extension" /> <min value="0" /> <max value="*" /> </base> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Extension.id"> <path value="Extension.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Extension.extension"> <path value="Extension.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="0" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Extension.url"> <path value="Extension.url" /> <representation value="xmlAttr" /> <short value="identifies the meaning of the extension" /> <definition value="Source of the definition for the extension code - a logical name or a URL." /> <comment value="The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension." /> <min value="1" /> <max value="1" /> <base> <path value="Extension.url" /> <min value="1" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="uri" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <fixedUri value="http://mpd.noma.no/structuredefinition/substance-classification" /> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Extension.value[x]"> <path value="Extension.value[x]" /> <short value="Value of extension" /> <definition value="Value of extension - must be one of a constrained set of the data types (see [Extensibility](extensibility.html) for a list)." /> <min value="0" /> <max value="1" /> <base> <path value="Extension.value[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> </snapshot> <differential> <element id="Extension"> <path value="Extension" /> <short value="Classifies the substance" /> <definition value="Optional xtension for classifying substances. Possible classification categories: - All the substance's ATC code(s). One entry per code. - The substance's E-number(s). One entry per e-number. - Whether the substance is therapeutic (only published when "true") - Whether the substance is a prodrug (only published when "true") - Whether the substance is complex (only published when "true")" /> <comment value="##### Published (optional) classification categories: ###### **E-Number** The substance's [E-number(s)](https://ec.europa.eu/food/food-feed-portal/screen/food-additives/search). A substance can have multiple e-numbers. Cardinality: 0..* Code: The E-number Display: The E-number name (substance) System URL: [https://mpd.noma.no/codesystem/e-number](https://mpd.noma.no/codesystem/e-number) ###### **Is Therapeutic** Whether the substance is therapeutic (only published when "true"). Cardinality: 0..1 Code: "true" Display: "Er terapautisk del" System URL: [https://mpd.noma.no/codesystem/is-active-moiety](https://mpd.noma.no/codesystem/is-active-moiety) ###### **Is Prodrug** Whether the substance is a prodrug (only published when "true") Cardinality: 0..1 Code: "true" Display: "Er prodrug" System URL: [https://mpd.noma.no/codesystem/is-prodrug](https://mpd.noma.no/codesystem/is-prodrug) ###### **Is Complex** Whether the substance is complex (only published when "true") Cardinality: 0..1 Code: "true" Display: "Er kompleks" System URL: [https://mpd.noma.no/codesystem/is-complex-substance](https://mpd.noma.no/codesystem/is-complex-substance) ###### **ATC codes** All the substance's ATC code(s). Human codes only. Cardinality: 0..* Code: The ATC code Display: The (substances) name System URLs, one per first-level ATC: | ATC Category Name | Source | URL (GUPRI) | | :------- | :------ |:------ | | ATC (A) Alimentary tract and metabolism | WHO | [https://mpd.noma.no/codesystem/atc-a-alimentary-tract-and-metabolism](https://mpd.noma.no/codesystem/atc-a-alimentary-tract-and-metabolism) | | ATC (J) Antiinfectives | WHO | [https://mpd.noma.no/codesystem/atc-j-antiinfectives-for-systemic-use](https://mpd.noma.no/codesystem/atc-j-antiinfectives-for-systemic-use) | | ATC (L) Antineoplastic, immunomodulating agents | WHO | [https://mpd.noma.no/codesystem/atc-l-antineoplastic-and-immunomodulating-agents](https://mpd.noma.no/codesystem/atc-l-antineoplastic-and-immunomodulating-agents) | | ATC (P) Antiparasitic Products | WHO | [https://mpd.noma.no/codesystem/atc-p-antiparasitic-products-insecticides-and-repellents](https://mpd.noma.no/codesystem/atc-p-antiparasitic-products-insecticides-and-repellents) | | ATC (B) Blood, Blood Forming Organs | WHO | [https://mpd.noma.no/codesystem/atc-b-blood-and-blood-forming-organs](https://mpd.noma.no/codesystem/atc-b-blood-and-blood-forming-organs) | | ATC (C) Cardiovascular System | WHO | [https://mpd.noma.no/codesystem/atc-c-cardiovascular-system](https://mpd.noma.no/codesystem/atc-c-cardiovascular-system) | | ATC (D) Dermatologicals | WHO | [https://mpd.noma.no/codesystem/atc-d-dermatologicals](https://mpd.noma.no/codesystem/atc-d-dermatologicals) | | ATC (G) Genito urinary System | WHO | [https://mpd.noma.no/codesystem/atc-g-genito-urinary-system-and-sex-hormones](https://mpd.noma.no/codesystem/atc-g-genito-urinary-system-and-sex-hormones) | | ATC (M) Musculo-skeletal System | WHO | [https://mpd.noma.no/codesystem/atc-m-musculo-skeletal-system](https://mpd.noma.no/codesystem/atc-m-musculo-skeletal-system) | | ATC (N) Nervous system | WHO | [https://mpd.noma.no/codesystem/atc-n-nervous-system](https://mpd.noma.no/codesystem/atc-n-nervous-system) | | ATC (R) Respiratory System | WHO | [https://mpd.noma.no/codesystem/atc-r-respiratory-system](https://mpd.noma.no/codesystem/atc-r-respiratory-system) | | ATC (S) Sensory Organs | WHO | [https://mpd.noma.no/codesystem/atc-s-sensory-organs](https://mpd.noma.no/codesystem/atc-s-sensory-organs) | | ATC (H) Systemic Hormonal Preparations | WHO | [https://mpd.noma.no/codesystem/atc-h-systemic-hormonal-preparations-excl-sex-hormones-and-insulins](https://mpd.noma.no/codesystem/atc-h-systemic-hormonal-preparations-excl-sex-hormones-and-insulins) | | ATC (V) Various | WHO | [https://mpd.noma.no/codesystem/atc-v-various](https://mpd.noma.no/codesystem/atc-v-various) |" /> </element> <element id="Extension.extension"> <path value="Extension.extension" /> <max value="0" /> </element> <element id="Extension.url"> <path value="Extension.url" /> <fixedUri value="http://mpd.noma.no/structuredefinition/substance-classification" /> </element> <element id="Extension.value[x]"> <path value="Extension.value[x]" /> <type> <code value="CodeableConcept" /> </type> </element> </differential> </StructureDefinition>