{
  "resourceType": "StructureDefinition",
  "id": "pop-loss-of-heterozygosity",
  "url": "https://simplifier.net/pop/StructureDefinition/pop-loss-of-heterozygosity",
  "version": "0.0.1",
  "name": "LossOfHeterozygosity",
  "title": "Loss Of Heterozygosity (LOH)",
  "status": "draft",
  "date": "2023-09-21T13:26:41.2566819+00:00",
  "publisher": "Precision Oncology Project (USZ)",
  "description": "Numerical score used to identify regions in the genome where an individual has lost one copy of a specific gene or allele, often associated with genetic disorders and cancer research.",
  "fhirVersion": "4.0.1",
  "kind": "resource",
  "abstract": false,
  "type": "Observation",
  "baseDefinition": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-base",
  "derivation": "constraint",
  "differential": {
    "element": [
      {
        "id": "Observation.code",
        "path": "Observation.code",
        "patternCodeableConcept": {
          "coding": [
            {
              "system": "http://sequenceontology.org/",
              "code": "SO:0001786"
            }
          ]
        }
      },
      {
        "id": "Observation.value[x]",
        "path": "Observation.value[x]",
        "short": "LOH score",
        "type": [
          {
            "code": "Quantity"
          }
        ]
      }
    ]
  }
}