<status value="draft" /> <date value="2023-09-22T08:15:35.7518841+00:00" /> <publisher value="Precision Oncology Project (USZ)" /> <description value="Cancer treatment response monitoring by imaging techniques to assess and track the effectiveness of cancer therapies and their impact on tumor size and progression." /> <fhirVersion value="4.0.1" /> <kind value="resource" /> <abstract value="false" /> <type value="Observation" /> <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Observation" /> <derivation value="constraint" /> <differential> <element id="Observation.category"> <path value="Observation.category" /> <patternCodeableConcept> <coding> <system value="http://terminology.hl7.org/CodeSystem/observation-category" /> <code value="imaging" /> </coding> </patternCodeableConcept> </element> <element id="Observation.code"> <path value="Observation.code" /> <patternCodeableConcept> <coding> <system value="http://snomed.info/sct" /> <code value="182985004" /> </coding> </patternCodeableConcept> </element> <element id="Observation.subject"> <path value="Observation.subject" /> <type> <code value="Reference" /> <targetProfile value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-cancer-patient" /> </type> </element> <element id="Observation.focus"> <path value="Observation.focus" /> <type> <code value="Reference" /> <targetProfile value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-primary-cancer-condition" /> <targetProfile value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-secondary-cancer-condition" /> </type> </element> <element id="Observation.effective[x]"> <path value="Observation.effective[x]" /> <type> <code value="dateTime" /> </type> </element> <element id="Observation.value[x]"> <path value="Observation.value[x]" /> <short value="RECIST coded value" /> <type> <code value="CodeableConcept" /> </type> <binding> <strength value="required" /> <description value="RECIST coded values" /> <valueSet value="http://loinc.org/vs/LL4721-8" /> </binding> </element> <element id="Observation.interpretation"> <path value="Observation.interpretation" /> <short value="Intepretation of the RECIST value" /> <binding> <strength value="required" /> <valueSet value="https://pop.org/fhir/ValueSets/pop-treatment-response-interpretations" /> </binding> </element> <element id="Observation.bodySite"> <path value="Observation.bodySite" /> <binding> <strength value="preferred" /> <description value="Codes describing anatomical locations" /> <valueSet value="http://hl7.org/fhir/us/mcode/ValueSet/mcode-radiotherapy-treatment-location-vs" /> </binding> </element> <element id="Observation.bodySite.extension:locationQualifier"> <path value="Observation.bodySite.extension" /> <sliceName value="locationQualifier" /> <max value="1" /> <type> <code value="Extension" /> <profile value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-body-location-qualifier" /> </type> <isModifier value="false" /> </element> <element id="Observation.bodySite.extension:lateralityQualifier"> <path value="Observation.bodySite.extension" /> <sliceName value="lateralityQualifier" /> <max value="1" /> <type> <code value="Extension" /> <profile value="http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-laterality-qualifier" /> </type> <isModifier value="false" /> </element> <element id="Observation.method"> <path value="Observation.method" /> <binding> <strength value="preferred" /> <valueSet value="https://pop.org/fhir/ValueSets/pop-cancer-treatment-response-observation-methods" /> </binding> </element> <element id="Observation.specimen"> <path value="Observation.specimen" /> <max value="0" /> </element> <element id="Observation.device"> <path value="Observation.device" /> <max value="0" /> </element> <element id="Observation.referenceRange"> <path value="Observation.referenceRange" /> <max value="0" /> </element> <element id="Observation.hasMember"> <path value="Observation.hasMember" /> <max value="0" /> </element> <element id="Observation.component"> <path value="Observation.component" /> <max value="0" /> </element> </differential> </StructureDefinition>