{ "resourceType": "StructureDefinition", "id": "PharmacogeneticLaboratoryTest", "url": "http://openehr.org.nl/zibs/StructureDefinition/PharmacogeneticLaboratoryTest", "version": "1.0.0-alpha.3", "name": "PharmacogeneticLaboratoryTest", "title": "PGX - Pharmacogenetics diagnostic report", "status": "active", "description": "`[openEHR-EHR-OBSERVATION.laboratory_test_result.v1 ]`\n The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual.)", "fhirVersion": "4.0.1", "kind": "logical", "abstract": false, "type": "http://openehr.org.nl/zibs/StructureDefinition/PharmacogeneticLaboratoryTest", "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Element", "derivation": "specialization", "snapshot": { "element": [ { "id": "PharmacogeneticLaboratoryTest", "path": "PharmacogeneticLaboratoryTest", "short": "PGX - Pharmacogenetics diagnostic report", "definition": "`[openEHR-EHR-OBSERVATION.laboratory_test_result.v1 ]`\n The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual.)", "min": 0, "max": "*", "base": { "path": "PharmacogeneticLaboratoryTest", "min": 0, "max": "*" }, "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.id", "path": "PharmacogeneticLaboratoryTest.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). 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If the width is non-zero, it is the time point of the trailing edge of the event.)", "min": 1, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.time", "min": 1, "max": "1" }, "type": [ { "code": "dateTime" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.testName", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.testName", "short": "Test name", "definition": "`[at0005 ]`\n Name of the laboratory investigation performed on the specimen(s).)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 1, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.testName", "min": 1, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.clinicalInformationProvided", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.clinicalInformationProvided", "short": "Clinical information provided", "definition": "`[at0100 ]`\n Description of clinical information available at the time of interpretation of results.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.clinicalInformationProvided", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult", "short": "Laboratory result", "definition": "`[openEHR-EHR-CLUSTER.laboratory_test_analyte.v1 ]`\n The result of a laboratory test for a single analyte value.)", "min": 0, "max": "*", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult", "min": 0, "max": "*" }, "type": [ { "code": "BackboneElement" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.id", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). 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Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. 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In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.analyteName", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult", "short": "Pharmacogenetic test result", "definition": "`[openEHR-EHR-CLUSTER.pharmacogenetic_result.v0 ]`\n Findings on pharmacogenetic testing for a single gene.)", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult", "min": 0, "max": "1" }, "type": [ { "code": "BackboneElement" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.id", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). 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In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 1, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.geneSymbol", "min": 1, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.diplotype", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.diplotype", "short": "Diplotype", "definition": "`[at0004 ]`\n A textual representation of the diplotype, normally as string of characters, either as as gene change descriptors or star allele diplotypes.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.diplotype", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.phenotype", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.phenotype", "short": "Phenotype", "definition": "`[at0052 ]`\n The estimated pharmacological impact of the identified genotype.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.phenotype", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "binding": { "strength": "required", "valueSet": "http://example.org/ValueSet/Phenotype" }, "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.overallActivityScore", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.overallActivityScore", "short": "Overall activity score", "definition": "`[at0080 | 1]`\n An associated derived activity score, based on known association with specific genotypes and individual allele activity values, which is required to assess metaboliser status for some phenotypes.)", "comment": "The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.overallActivityScore", "min": 0, "max": "1" }, "type": [ { "code": "Quantity" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "qty-3", "severity": "error", "human": "If a code for the unit is present, the system SHALL also be present", "expression": "code.empty() or system.exists()", "xpath": "not(exists(f:code)) or exists(f:system)", "source": "http://hl7.org/fhir/StructureDefinition/Quantity" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "SN (see also Range) or CQ" }, { "identity": "rim", "map": "PQ, IVL, MO, CO, depending on the values" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue", "short": "Individual activity value", "definition": "`[at0084 ]`\n A list of enzyme activity values each associated with a specific allele, which are used to derive the Overall activity score.)", "min": 0, "max": "*", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue", "min": 0, "max": "*" }, "type": [ { "code": "BackboneElement" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue.id", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). 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Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).", "alias": [ "extensions", "user content", "modifiers" ], "min": 0, "max": "*", "base": { "path": "BackboneElement.modifierExtension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "isModifier": true, "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them", "isSummary": true, "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.knowledgeBaseName", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.knowledgeBaseName", "short": "Knowledge base name", "definition": "`[at0001 ]`\n The name of the knowledge base.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 1, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.knowledgeBaseName", "min": 1, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.itemName", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.itemName", "short": "Item name", "definition": "`[at0005 ]`\n The name of the referenced item within the knowledge base.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.itemName", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail", "short": "Variant detail", "definition": "`[openEHR-EHR-CLUSTER.genomic_variant_result.v1 ]`\n Findings and annotations related to one variant found in a human individual by a sequencing test.)", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail", "min": 0, "max": "1" }, "type": [ { "code": "BackboneElement" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.id", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.", "min": 0, "max": "1", "base": { "path": "Element.id", "min": 0, "max": "1" }, "type": [ { "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type", "valueUrl": "string" } ], "code": "http://hl7.org/fhirpath/System.String" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.extension", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.extension", "slicing": { "discriminator": [ { "type": "value", "path": "url" } ], "description": "Extensions are always sliced by (at least) url", "rules": "open" }, "short": "Additional content defined by implementations", "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "alias": [ "extensions", "user content" ], "min": 0, "max": "*", "base": { "path": "Element.extension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.modifierExtension", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.modifierExtension", "short": "Extensions that cannot be ignored even if unrecognized", "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).", "alias": [ "extensions", "user content", "modifiers" ], "min": 0, "max": "*", "base": { "path": "BackboneElement.modifierExtension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "isModifier": true, "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them", "isSummary": true, "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment", "short": "GA4GH VRS attachment", "definition": "`[openEHR-EHR-CLUSTER.media_file.v1 ]`\n A media file that is acquired or used as part of the healthcare process, and associated metadata.)", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment", "min": 0, "max": "1" }, "type": [ { "code": "BackboneElement" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.id", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.", "min": 0, "max": "1", "base": { "path": "Element.id", "min": 0, "max": "1" }, "type": [ { "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type", "valueUrl": "string" } ], "code": "http://hl7.org/fhirpath/System.String" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.extension", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.extension", "slicing": { "discriminator": [ { "type": "value", "path": "url" } ], "description": "Extensions are always sliced by (at least) url", "rules": "open" }, "short": "Additional content defined by implementations", "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "alias": [ "extensions", "user content" ], "min": 0, "max": "*", "base": { "path": "Element.extension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.modifierExtension", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.modifierExtension", "short": "Extensions that cannot be ignored even if unrecognized", "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).", "alias": [ "extensions", "user content", "modifiers" ], "min": 0, "max": "*", "base": { "path": "BackboneElement.modifierExtension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "isModifier": true, "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them", "isSummary": true, "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.content", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.content", "short": "Content", "definition": "`[at0001 ]`\n Digital representation of the media file.)", "comment": "When providing a summary view (for example with Observation.value[x]) Attachment should be represented with a brief display text such as \"Signed Procedure Consent\".", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.content", "min": 0, "max": "1" }, "type": [ { "code": "Attachment" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "att-1", "severity": "error", "human": "If the Attachment has data, it SHALL have a contentType", "expression": "data.empty() or contentType.exists()", "xpath": "not(exists(f:data)) or exists(f:contentType)", "source": "http://hl7.org/fhir/StructureDefinition/Attachment" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "ED/RP" }, { "identity": "rim", "map": "ED" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.contentName", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.contentName", "short": "Content name", "definition": "`[at0002 ]`\n Descriptive name or title for the media file.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.contentName", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.created[x]", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.created[x]", "short": "Created", "definition": "at0004: The date/time, partial date or period when the media file was generated or authored.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.created[x]", "min": 0, "max": "1" }, "type": [ { "code": "dateTime" }, { "code": "Period" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.overallRecommendation", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.overallRecommendation", "short": "Overall recommendation", "definition": "`[at0057 ]`\n Narrative description of the key findings.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.overallRecommendation", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.testMethod", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.testMethod", "short": "Test method", "definition": "`[at0121 ]`\n Description about the method used to perform the test.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.testMethod", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.testingDevice", "short": "Testing device", "definition": "`[openEHR-EHR-CLUSTER.device.v1 ]`\n An instrument, apparatus, implant, material or similar, used in the provision of healthcare. In this context, a medical device includes a broad range of devices which act through a variety of physical, mechanical, thermal or similar means but specifically excludes devices which act through medicinal means such as pharmacological, metabolic or immunological methods. The scope is inclusive of disposable devices as well as durable or persisting devices that require tracking, maintenance activities or regular calibration, recognising that each type of device has specific data recording requirements.)", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.testingDevice", "min": 0, "max": "1" }, "type": [ { "code": "BackboneElement" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice.id", "path": "PharmacogeneticLaboratoryTest.testingDevice.id", "representation": [ "xmlAttr" ], "short": "Unique id for inter-element referencing", "definition": "Unique id for the element within a resource (for internal references). 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Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "alias": [ "extensions", "user content" ], "min": 0, "max": "*", "base": { "path": "Element.extension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice.modifierExtension", "path": "PharmacogeneticLaboratoryTest.testingDevice.modifierExtension", "short": "Extensions that cannot be ignored even if unrecognized", "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).", "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.", "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).", "alias": [ "extensions", "user content", "modifiers" ], "min": 0, "max": "*", "base": { "path": "BackboneElement.modifierExtension", "min": 0, "max": "*" }, "type": [ { "code": "Extension" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" }, { "key": "ext-1", "severity": "error", "human": "Must have either extensions or value[x], not both", "expression": "extension.exists() != value.exists()", "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])", "source": "http://hl7.org/fhir/StructureDefinition/Extension" } ], "isModifier": true, "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them", "isSummary": true, "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "rim", "map": "N/A" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice.deviceName", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.testingDevice.deviceName", "short": "Device name", "definition": "`[at0001 ]`\n Identification of the medical device, preferably by a common name, a formal fully descriptive name or, if required, by class or category of device.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 1, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.testingDevice.deviceName", "min": 1, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice.type", "extension": [ { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode": "normative" }, { "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version", "valueCode": "4.0.0" } ], "path": "PharmacogeneticLaboratoryTest.testingDevice.type", "short": "Type", "definition": "`[at0003 ]`\n The category or kind of device.)", "comment": "Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.", "min": 0, "max": "1", "base": { "path": "PharmacogeneticLaboratoryTest.testingDevice.type", "min": 0, "max": "1" }, "type": [ { "code": "CodeableConcept" } ], "condition": [ "ele-1" ], "constraint": [ { "key": "ele-1", "severity": "error", "human": "All FHIR elements must have a @value or children", "expression": "hasValue() or (children().count() > id.count())", "xpath": "@value|f:*|h:div", "source": "http://hl7.org/fhir/StructureDefinition/Element" } ], "mapping": [ { "identity": "rim", "map": "n/a" }, { "identity": "v2", "map": "CE/CNE/CWE" }, { "identity": "rim", "map": "CD" }, { "identity": "orim", "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD" } ] } ] }, "differential": { "element": [ { "id": "PharmacogeneticLaboratoryTest", "path": "PharmacogeneticLaboratoryTest", "short": "PGX - Pharmacogenetics diagnostic report", "definition": "`[openEHR-EHR-OBSERVATION.laboratory_test_result.v1 ]`\n The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual.)" }, { "id": "PharmacogeneticLaboratoryTest.time", "path": "PharmacogeneticLaboratoryTest.time", "short": "time", "definition": "`[RM ]`\n `OBSERVATION.EVENT.time` - Time of this Observation event. If the width is non-zero, it is the time point of the trailing edge of the event.)", "min": 1, "max": "1", "type": [ { "code": "dateTime" } ] }, { "id": "PharmacogeneticLaboratoryTest.testName", "path": "PharmacogeneticLaboratoryTest.testName", "short": "Test name", "definition": "`[at0005 ]`\n Name of the laboratory investigation performed on the specimen(s).)", "min": 1, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.clinicalInformationProvided", "path": "PharmacogeneticLaboratoryTest.clinicalInformationProvided", "short": "Clinical information provided", "definition": "`[at0100 ]`\n Description of clinical information available at the time of interpretation of results.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult", "path": "PharmacogeneticLaboratoryTest.laboratoryResult", "short": "Laboratory result", "definition": "`[openEHR-EHR-CLUSTER.laboratory_test_analyte.v1 ]`\n The result of a laboratory test for a single analyte value.)", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.analyteName", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.analyteName", "short": "Analyte name", "definition": "`[at0024 ]`\n The name of the analyte result.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult", "short": "Pharmacogenetic test result", "definition": "`[openEHR-EHR-CLUSTER.pharmacogenetic_result.v0 ]`\n Findings on pharmacogenetic testing for a single gene.)", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.geneSymbol", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.geneSymbol", "short": "Gene symbol", "definition": "`[at0003 ]`\n The official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.)", "min": 1, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.diplotype", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.diplotype", "short": "Diplotype", "definition": "`[at0004 ]`\n A textual representation of the diplotype, normally as string of characters, either as as gene change descriptors or star allele diplotypes.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.phenotype", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.phenotype", "short": "Phenotype", "definition": "`[at0052 ]`\n The estimated pharmacological impact of the identified genotype.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ], "binding": { "strength": "required", "valueSet": "http://example.org/ValueSet/Phenotype" } }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.overallActivityScore", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.overallActivityScore", "short": "Overall activity score", "definition": "`[at0080 | 1]`\n An associated derived activity score, based on known association with specific genotypes and individual allele activity values, which is required to assess metaboliser status for some phenotypes.)", "min": 0, "max": "1", "type": [ { "code": "Quantity" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue", "short": "Individual activity value", "definition": "`[at0084 ]`\n A list of enzyme activity values each associated with a specific allele, which are used to derive the Overall activity score.)", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue.alleleHaplotype", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue.alleleHaplotype", "short": "Allele haplotype", "definition": "`[at0086 ]`\n The allele haplotype descriptor associated with the activity value.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue.activityValue", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.individualActivityValue.activityValue", "short": "Activity value", "definition": "`[at0085 | 1]`\n An associated derived activity score, based on known association with specific genotypes, which is required to assess metaboliser status for some phenotypes.)", "min": 0, "max": "1", "type": [ { "code": "Quantity" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested", "short": "Per-allele tested", "definition": "`[at0097 ]`\n A list of the specific alleles tested by this pharmacogenetic test, as the specific alleles may vary between tests.)", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber", "short": "SNP rsNumber", "definition": "`[openEHR-EHR-CLUSTER.knowledge_base_reference.v1 ]`\n A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource.)", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.knowledgeBaseName", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.knowledgeBaseName", "short": "Knowledge base name", "definition": "`[at0001 ]`\n The name of the knowledge base.)", "min": 1, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.itemName", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.perAlleleTested.sNPRsNumber.itemName", "short": "Item name", "definition": "`[at0005 ]`\n The name of the referenced item within the knowledge base.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail", "short": "Variant detail", "definition": "`[openEHR-EHR-CLUSTER.genomic_variant_result.v1 ]`\n Findings and annotations related to one variant found in a human individual by a sequencing test.)", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment", "short": "GA4GH VRS attachment", "definition": "`[openEHR-EHR-CLUSTER.media_file.v1 ]`\n A media file that is acquired or used as part of the healthcare process, and associated metadata.)", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.content", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.content", "short": "Content", "definition": "`[at0001 ]`\n Digital representation of the media file.)", "min": 0, "max": "1", "type": [ { "code": "Attachment" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.contentName", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.contentName", "short": "Content name", "definition": "`[at0002 ]`\n Descriptive name or title for the media file.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.created[x]", "path": "PharmacogeneticLaboratoryTest.laboratoryResult.pharmacogeneticTestResult.variantDetail.gA4GHVRSAttachment.created[x]", "short": "Created", "definition": "at0004: The date/time, partial date or period when the media file was generated or authored.", "min": 0, "max": "1", "type": [ { "code": "dateTime" }, { "code": "Period" } ] }, { "id": "PharmacogeneticLaboratoryTest.overallRecommendation", "path": "PharmacogeneticLaboratoryTest.overallRecommendation", "short": "Overall recommendation", "definition": "`[at0057 ]`\n Narrative description of the key findings.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.testMethod", "path": "PharmacogeneticLaboratoryTest.testMethod", "short": "Test method", "definition": "`[at0121 ]`\n Description about the method used to perform the test.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice", "path": "PharmacogeneticLaboratoryTest.testingDevice", "short": "Testing device", "definition": "`[openEHR-EHR-CLUSTER.device.v1 ]`\n An instrument, apparatus, implant, material or similar, used in the provision of healthcare. In this context, a medical device includes a broad range of devices which act through a variety of physical, mechanical, thermal or similar means but specifically excludes devices which act through medicinal means such as pharmacological, metabolic or immunological methods. The scope is inclusive of disposable devices as well as durable or persisting devices that require tracking, maintenance activities or regular calibration, recognising that each type of device has specific data recording requirements.)", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice.deviceName", "path": "PharmacogeneticLaboratoryTest.testingDevice.deviceName", "short": "Device name", "definition": "`[at0001 ]`\n Identification of the medical device, preferably by a common name, a formal fully descriptive name or, if required, by class or category of device.)", "min": 1, "max": "1", "type": [ { "code": "CodeableConcept" } ] }, { "id": "PharmacogeneticLaboratoryTest.testingDevice.type", "path": "PharmacogeneticLaboratoryTest.testingDevice.type", "short": "Type", "definition": "`[at0003 ]`\n The category or kind of device.)", "min": 0, "max": "1", "type": [ { "code": "CodeableConcept" } ] } ] } }