<status value="active" /> <description value="[openEHR-EHR-OBSERVATION.laboratory_test_result.v1] The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual." /> <fhirVersion value="4.0.1" /> <kind value="logical" /> <abstract value="false" /> <type value="http://openehr.org/StructureDefinition/LaboratoryTestResult" /> <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Element" /> <derivation value="specialization" /> <snapshot> <element id="LaboratoryTestResult"> <path value="LaboratoryTestResult" /> <short value="GENOC - Familial risk Tumour genomics report" /> <definition value="[openEHR-EHR-OBSERVATION.laboratory_test_result.v1] The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual." /> <min value="0" /> <max value="*" /> <base> <path value="LaboratoryTestResult" /> <min value="0" /> <max value="*" /> </base> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.id"> <path value="LaboratoryTestResult.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.extension"> <path value="LaboratoryTestResult.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult" /> <short value="Laboratory test result" /> <definition value="[openEHR-EHR-OBSERVATION.laboratory_test_result.v1] The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual." /> <min value="0" /> <max value="*" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult" /> <min value="0" /> <max value="*" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.time"> <path value="LaboratoryTestResult.LaboratoryTestResult.time" /> <short value="time" /> <definition value="[RM] `OBSERVATION.EVENT.time` - Time of this Observation event. If the width is non-zero, it is the time point of the trailing edge of the event." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.time" /> <min value="1" /> <max value="1" /> </base> <type> <code value="dateTime" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.testName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.testName" /> <short value="Test name" /> <definition value="[at0005] Name of the laboratory investigation performed on the specimen(s)." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.testName" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen" /> <short value="Specimen" /> <definition value="[openEHR-EHR-CLUSTER.specimen.v1] A physical sample collected from, or related to, an individual for the purpose of investigation, examination or analysis." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.specimenType"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.specimenType" /> <short value="Specimen type" /> <definition value="[at0029] The type of specimen." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.specimenType" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratorySpecimenIdentifier"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratorySpecimenIdentifier" /> <short value="Laboratory specimen identifier" /> <definition value="[at0001] A unique identifier of the specimen, normally assigned by the laboratory." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratorySpecimenIdentifier" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Identifier" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CX / EI (occasionally, more often EI maps to a resource id or a URL)" /> </mapping> <mapping> <identity value="rim" /> <map value="II - The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs. Also maps to Role[classCode=IDENT]" /> </mapping> <mapping> <identity value="servd" /> <map value="Identifier" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratoryRunIdentifier"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratoryRunIdentifier" /> <short value="Laboratory run identifier" /> <definition value="[at0088] A unique identifier of the specimen, assigned by a party external to the laboratory." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratoryRunIdentifier" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.clinicalInformationProvided"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.clinicalInformationProvided" /> <short value="Clinical information provided" /> <definition value="[at0100] Description of clinical information available at the time of interpretation of results." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.clinicalInformationProvided" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult" /> <short value="Laboratory result" /> <definition value="[openEHR-EHR-CLUSTER.laboratory_test_analyte.v1] The result of a laboratory test for a single analyte value." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.analyteName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.analyteName" /> <short value="Analyte name" /> <definition value="[at0024] The name of the analyte result." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.analyteName" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult" /> <short value="Genomic variant result" /> <definition value="[openEHR-EHR-CLUSTER.genomic_variant_result.v1] Findings and annotations related to one variant found in a human individual by a sequencing test." /> <min value="0" /> <max value="*" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult" /> <min value="0" /> <max value="*" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP" /> <short value="dbSNP" /> <definition value="[openEHR-EHR-CLUSTER.knowledge_base_reference.v1] A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource." /> <min value="0" /> <max value="*" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP" /> <min value="0" /> <max value="*" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseName" /> <short value="Knowledge base name" /> <definition value="[at0001] The name of the knowledge base." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseName" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseURI" /> <short value="Knowledge base URI" /> <definition value="[at0008] The hyperlink to the referenced knowledge base." /> <comment value="see http://en.wikipedia.org/wiki/Uniform_resource_identifier" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseURI" /> <min value="0" /> <max value="1" /> </base> <type> <code value="uri" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.itemName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.itemName" /> <short value="Item name" /> <definition value="[at0005] The name of the referenced item within the knowledge base." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.itemName" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant" /> <short value="Simple variant" /> <definition value="[openEHR-EHR-CLUSTER.simple_variant_genoceanic.v1] A sequence change where, compared to a reference sequence, a one or more nucleotides are changed." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.chromosomeLabel"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.chromosomeLabel" /> <short value="Chromosome label" /> <definition value="[at0012] Chromosome identifier." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.chromosomeLabel" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <binding> <strength value="preferred" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultChromosomeLabel" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.variantType"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.variantType" /> <short value="Variant type" /> <definition value="[at0039] The variant type e.g Snv, indel etc." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.variantType" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript" /> <short value="Transcript" /> <definition value="[at0008] Structured details about the transcript which is potentially affected by the variant." /> <min value="0" /> <max value="*" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript" /> <min value="0" /> <max value="*" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension" /> <short value="Transcript extension" /> <definition value="[openEHR-EHR-CLUSTER.transcript_extension_genoceanic.v1] Transcript extension GenOceanic" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.transcriptBiotype"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.transcriptBiotype" /> <short value="Transcript biotype" /> <definition value="[at0001]" /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.transcriptBiotype" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.consequence"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.consequence" /> <short value="Consequence" /> <definition value="[at0002]" /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="*" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.consequence" /> <min value="0" /> <max value="*" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <binding> <strength value="required" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultConsequence" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.dNAChangeCClinVar"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.dNAChangeCClinVar" /> <short value="DNA change (c.ClinVar)" /> <definition value="[at0011] Description of the variation at the DNA level following the HGVS nomenclature." /> <comment value="Note that FHIR strings SHALL NOT exceed 1MB in size" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.dNAChangeCClinVar" /> <min value="0" /> <max value="1" /> </base> <type> <code value="string" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aminoAcidChangePClinvar"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aminoAcidChangePClinvar" /> <short value="Amino acid change (p.Clinvar)" /> <definition value="[at0012] Description of the variation at the protein level following the HGVS nomenclature." /> <comment value="Note that FHIR strings SHALL NOT exceed 1MB in size" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aminoAcidChangePClinvar" /> <min value="0" /> <max value="1" /> </base> <type> <code value="string" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact" /> <short value="Predicted impact" /> <definition value="[at0015] Estimate of the effects that the variant may have on the transcript." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar" /> <short value="Clinvar" /> <definition value="[openEHR-EHR-CLUSTER.knowledge_base_reference.v1] A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseName" /> <short value="Knowledge base name" /> <definition value="[at0001] The name of the knowledge base." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseName" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseURI" /> <short value="Knowledge base URI" /> <definition value="[at0008] The hyperlink to the referenced knowledge base." /> <comment value="see http://en.wikipedia.org/wiki/Uniform_resource_identifier" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseURI" /> <min value="0" /> <max value="1" /> </base> <type> <code value="uri" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemName" /> <short value="Item name" /> <definition value="[at0005] The name of the referenced item within the knowledge base." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemName" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemURI" /> <short value="Item URI" /> <definition value="[at0003] The hyperlink to the referenced item within the knowledge base." /> <comment value="see http://en.wikipedia.org/wiki/Uniform_resource_identifier" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemURI" /> <min value="0" /> <max value="1" /> </base> <type> <code value="uri" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact" /> <short value="Functional impact" /> <definition value="[at0052] Interpretation of the variation linked to a specific paper." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.impact"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.impact" /> <short value="Impact" /> <definition value="[at0054] Single word or phrase describing the reported impact of the specific variant." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.impact" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO" /> <short value="ESMO" /> <definition value="[openEHR-EHR-CLUSTER.knowledge_base_reference.v1] A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseName" /> <short value="Knowledge base name" /> <definition value="[at0001] The name of the knowledge base." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseName" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseURI" /> <short value="Knowledge base URI" /> <definition value="[at0008] The hyperlink to the referenced knowledge base." /> <comment value="see http://en.wikipedia.org/wiki/Uniform_resource_identifier" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseURI" /> <min value="0" /> <max value="1" /> </base> <type> <code value="uri" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.itemName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.itemName" /> <short value="Item name" /> <definition value="[at0005] The name of the referenced item within the knowledge base." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.itemName" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene" /> <short value="Gene" /> <definition value="[at0019] Structured details about the gene carrying the variant." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.geneSymbol"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.geneSymbol" /> <short value="Gene symbol" /> <definition value="[at0020] The official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="1" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.geneSymbol" /> <min value="1" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aCMGClassification"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aCMGClassification" /> <short value="ACMG classification" /> <definition value="[at0058] The clinical significance according to the ACMG recommendations." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aCMGClassification" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <binding> <strength value="required" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultACMGClassification" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.bestTranscriptCandidate"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.bestTranscriptCandidate" /> <short value="Best transcript candidate" /> <definition value="[at0023] The ID of the transcript with the highest predicted impact." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.bestTranscriptCandidate" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.alleleFrequency"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.alleleFrequency" /> <short value="Allele frequency" /> <definition value="[at0047 | 1] The relative frequency of an allele at a particular locus." /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.alleleFrequency" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.genotype"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.genotype" /> <short value="Genotype" /> <definition value="[at0039] Genotype encoded as allele values." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.genotype" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.allelicState"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.allelicState" /> <short value="Allelic state" /> <definition value="[at0040] The level of occurrence of a single DNA marker within a set of chromosomes." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.allelicState" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <binding> <strength value="preferred" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultAllelicState" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile" /> <short value="Sourcefile" /> <definition value="[openEHR-EHR-CLUSTER.media_file.v1] A media file that is acquired or used as part of the healthcare process, and associated metadata." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.content"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.content" /> <short value="Content" /> <definition value="[at0001] Digital representation of the media file." /> <comment value="When providing a summary view (for example with Observation.value[x]) Attachment should be represented with a brief display text such as "Signed Procedure Consent"." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.content" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Attachment" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="att-1" /> <severity value="error" /> <human value="If the Attachment has data, it SHALL have a contentType" /> <expression value="data.empty() or contentType.exists()" /> <xpath value="not(exists(f:data)) or exists(f:contentType)" /> <source value="http://hl7.org/fhir/StructureDefinition/Attachment" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="ED/RP" /> </mapping> <mapping> <identity value="rim" /> <map value="ED" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.contentName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.contentName" /> <short value="Content name" /> <definition value="[at0002] Descriptive name or title for the media file." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.contentName" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.identifier"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.identifier" /> <short value="Identifier" /> <definition value="[at0010] Unique ID for the media file." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.identifier" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails" /> <short value="Review details" /> <definition value="[openEHR-EHR-CLUSTER.genomic_variant_review.v1] To support low-level recording of lab scientist review of specific variant clinical recommendation" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails" /> <min value="0" /> <max value="1" /> </base> <type> <code value="BackboneElement" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.id"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.extension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.modifierExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.dateReviewed"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.dateReviewed" /> <short value="Date reviewed" /> <definition value="[at0001]" /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.dateReviewed" /> <min value="0" /> <max value="1" /> </base> <type> <code value="dateTime" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewerName"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewerName" /> <short value="Reviewer name" /> <definition value="[at0002]" /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewerName" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewStatus"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewStatus" /> <short value="Review status" /> <definition value="[at0004]" /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewStatus" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.overallRecommendation"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.overallRecommendation" /> <short value="Overall recommendation" /> <definition value="[at0057] Narrative description of the key findings." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.overallRecommendation" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryInternalIdentifier"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryInternalIdentifier" /> <short value="Laboratory internal identifier" /> <definition value="[at0068] A local identifier assigned by the receiving Laboratory Information System (LIS) to track the test process." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryInternalIdentifier" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.testMethod"> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status"> <valueCode value="normative" /> </extension> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version"> <valueCode value="4.0.0" /> </extension> <path value="LaboratoryTestResult.LaboratoryTestResult.testMethod" /> <short value="Test method" /> <definition value="[at0121] Description about the method used to perform the test." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <min value="0" /> <max value="1" /> <base> <path value="LaboratoryTestResult.LaboratoryTestResult.testMethod" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> </element> </snapshot> <differential> <element id="LaboratoryTestResult"> <path value="LaboratoryTestResult" /> <short value="GENOC - Familial risk Tumour genomics report" /> <definition value="[openEHR-EHR-OBSERVATION.laboratory_test_result.v1] The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual." /> </element> <element id="LaboratoryTestResult.LaboratoryTestResult"> <path value="LaboratoryTestResult.LaboratoryTestResult" /> <short value="Laboratory test result" /> <definition value="[openEHR-EHR-OBSERVATION.laboratory_test_result.v1] The result, including findings and the laboratory's interpretation, of Pharmacogenetics investigation performed on specimens collected from an individual." /> <min value="0" /> <max value="*" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.time"> <path value="LaboratoryTestResult.LaboratoryTestResult.time" /> <short value="time" /> <definition value="[RM] `OBSERVATION.EVENT.time` - Time of this Observation event. If the width is non-zero, it is the time point of the trailing edge of the event." /> <min value="1" /> <max value="1" /> <type> <code value="dateTime" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.testName"> <path value="LaboratoryTestResult.LaboratoryTestResult.testName" /> <short value="Test name" /> <definition value="[at0005] Name of the laboratory investigation performed on the specimen(s)." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen" /> <short value="Specimen" /> <definition value="[openEHR-EHR-CLUSTER.specimen.v1] A physical sample collected from, or related to, an individual for the purpose of investigation, examination or analysis." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.specimenType"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.specimenType" /> <short value="Specimen type" /> <definition value="[at0029] The type of specimen." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratorySpecimenIdentifier"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratorySpecimenIdentifier" /> <short value="Laboratory specimen identifier" /> <definition value="[at0001] A unique identifier of the specimen, normally assigned by the laboratory." /> <min value="0" /> <max value="1" /> <type> <code value="Identifier" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratoryRunIdentifier"> <path value="LaboratoryTestResult.LaboratoryTestResult.specimen.laboratoryRunIdentifier" /> <short value="Laboratory run identifier" /> <definition value="[at0088] A unique identifier of the specimen, assigned by a party external to the laboratory." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.clinicalInformationProvided"> <path value="LaboratoryTestResult.LaboratoryTestResult.clinicalInformationProvided" /> <short value="Clinical information provided" /> <definition value="[at0100] Description of clinical information available at the time of interpretation of results." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult" /> <short value="Laboratory result" /> <definition value="[openEHR-EHR-CLUSTER.laboratory_test_analyte.v1] The result of a laboratory test for a single analyte value." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.analyteName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.analyteName" /> <short value="Analyte name" /> <definition value="[at0024] The name of the analyte result." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult" /> <short value="Genomic variant result" /> <definition value="[openEHR-EHR-CLUSTER.genomic_variant_result.v1] Findings and annotations related to one variant found in a human individual by a sequencing test." /> <min value="0" /> <max value="*" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP" /> <short value="dbSNP" /> <definition value="[openEHR-EHR-CLUSTER.knowledge_base_reference.v1] A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource." /> <min value="0" /> <max value="*" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseName" /> <short value="Knowledge base name" /> <definition value="[at0001] The name of the knowledge base." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.knowledgeBaseURI" /> <short value="Knowledge base URI" /> <definition value="[at0008] The hyperlink to the referenced knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="uri" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.itemName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.dbSNP.itemName" /> <short value="Item name" /> <definition value="[at0005] The name of the referenced item within the knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant" /> <short value="Simple variant" /> <definition value="[openEHR-EHR-CLUSTER.simple_variant_genoceanic.v1] A sequence change where, compared to a reference sequence, a one or more nucleotides are changed." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.chromosomeLabel"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.chromosomeLabel" /> <short value="Chromosome label" /> <definition value="[at0012] Chromosome identifier." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> <binding> <strength value="preferred" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultChromosomeLabel" /> </binding> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.variantType"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.simpleVariant.variantType" /> <short value="Variant type" /> <definition value="[at0039] The variant type e.g Snv, indel etc." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript" /> <short value="Transcript" /> <definition value="[at0008] Structured details about the transcript which is potentially affected by the variant." /> <min value="0" /> <max value="*" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension" /> <short value="Transcript extension" /> <definition value="[openEHR-EHR-CLUSTER.transcript_extension_genoceanic.v1] Transcript extension GenOceanic" /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.transcriptBiotype"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.transcriptBiotype" /> <short value="Transcript biotype" /> <definition value="[at0001]" /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.consequence"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.transcriptExtension.consequence" /> <short value="Consequence" /> <definition value="[at0002]" /> <min value="0" /> <max value="*" /> <type> <code value="CodeableConcept" /> </type> <binding> <strength value="required" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultConsequence" /> </binding> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.dNAChangeCClinVar"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.dNAChangeCClinVar" /> <short value="DNA change (c.ClinVar)" /> <definition value="[at0011] Description of the variation at the DNA level following the HGVS nomenclature." /> <min value="0" /> <max value="1" /> <type> <code value="string" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aminoAcidChangePClinvar"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aminoAcidChangePClinvar" /> <short value="Amino acid change (p.Clinvar)" /> <definition value="[at0012] Description of the variation at the protein level following the HGVS nomenclature." /> <min value="0" /> <max value="1" /> <type> <code value="string" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact" /> <short value="Predicted impact" /> <definition value="[at0015] Estimate of the effects that the variant may have on the transcript." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar" /> <short value="Clinvar" /> <definition value="[openEHR-EHR-CLUSTER.knowledge_base_reference.v1] A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseName" /> <short value="Knowledge base name" /> <definition value="[at0001] The name of the knowledge base." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.knowledgeBaseURI" /> <short value="Knowledge base URI" /> <definition value="[at0008] The hyperlink to the referenced knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="uri" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemName" /> <short value="Item name" /> <definition value="[at0005] The name of the referenced item within the knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.predictedImpact.clinvar.itemURI" /> <short value="Item URI" /> <definition value="[at0003] The hyperlink to the referenced item within the knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="uri" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact" /> <short value="Functional impact" /> <definition value="[at0052] Interpretation of the variation linked to a specific paper." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.impact"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.impact" /> <short value="Impact" /> <definition value="[at0054] Single word or phrase describing the reported impact of the specific variant." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO" /> <short value="ESMO" /> <definition value="[openEHR-EHR-CLUSTER.knowledge_base_reference.v1] A citation of a digital resource used as an source of authoritative or expert information, and/or to items contained within the resource." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseName" /> <short value="Knowledge base name" /> <definition value="[at0001] The name of the knowledge base." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseURI"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.knowledgeBaseURI" /> <short value="Knowledge base URI" /> <definition value="[at0008] The hyperlink to the referenced knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="uri" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.itemName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.functionalImpact.eSMO.itemName" /> <short value="Item name" /> <definition value="[at0005] The name of the referenced item within the knowledge base." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene" /> <short value="Gene" /> <definition value="[at0019] Structured details about the gene carrying the variant." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.geneSymbol"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.gene.geneSymbol" /> <short value="Gene symbol" /> <definition value="[at0020] The official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name." /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aCMGClassification"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.transcript.aCMGClassification" /> <short value="ACMG classification" /> <definition value="[at0058] The clinical significance according to the ACMG recommendations." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> <binding> <strength value="required" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultACMGClassification" /> </binding> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.bestTranscriptCandidate"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.bestTranscriptCandidate" /> <short value="Best transcript candidate" /> <definition value="[at0023] The ID of the transcript with the highest predicted impact." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.alleleFrequency"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.alleleFrequency" /> <short value="Allele frequency" /> <definition value="[at0047 | 1] The relative frequency of an allele at a particular locus." /> <min value="0" /> <max value="1" /> <type> <code value="Quantity" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.genotype"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.genotype" /> <short value="Genotype" /> <definition value="[at0039] Genotype encoded as allele values." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.allelicState"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.allelicState" /> <short value="Allelic state" /> <definition value="[at0040] The level of occurrence of a single DNA marker within a set of chromosomes." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> <binding> <strength value="preferred" /> <valueSet value="http://example.org/ValueSet/LaboratoryTestResultAllelicState" /> </binding> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile" /> <short value="Sourcefile" /> <definition value="[openEHR-EHR-CLUSTER.media_file.v1] A media file that is acquired or used as part of the healthcare process, and associated metadata." /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.content"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.content" /> <short value="Content" /> <definition value="[at0001] Digital representation of the media file." /> <min value="0" /> <max value="1" /> <type> <code value="Attachment" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.contentName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.contentName" /> <short value="Content name" /> <definition value="[at0002] Descriptive name or title for the media file." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.identifier"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.sourcefile.identifier" /> <short value="Identifier" /> <definition value="[at0010] Unique ID for the media file." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails" /> <short value="Review details" /> <definition value="[openEHR-EHR-CLUSTER.genomic_variant_review.v1] To support low-level recording of lab scientist review of specific variant clinical recommendation" /> <min value="0" /> <max value="1" /> <type> <code value="BackboneElement" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.dateReviewed"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.dateReviewed" /> <short value="Date reviewed" /> <definition value="[at0001]" /> <min value="0" /> <max value="1" /> <type> <code value="dateTime" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewerName"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewerName" /> <short value="Reviewer name" /> <definition value="[at0002]" /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewStatus"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryResult.genomicVariantResult.reviewDetails.reviewStatus" /> <short value="Review status" /> <definition value="[at0004]" /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.overallRecommendation"> <path value="LaboratoryTestResult.LaboratoryTestResult.overallRecommendation" /> <short value="Overall recommendation" /> <definition value="[at0057] Narrative description of the key findings." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.laboratoryInternalIdentifier"> <path value="LaboratoryTestResult.LaboratoryTestResult.laboratoryInternalIdentifier" /> <short value="Laboratory internal identifier" /> <definition value="[at0068] A local identifier assigned by the receiving Laboratory Information System (LIS) to track the test process." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> <element id="LaboratoryTestResult.LaboratoryTestResult.testMethod"> <path value="LaboratoryTestResult.LaboratoryTestResult.testMethod" /> <short value="Test method" /> <definition value="[at0121] Description about the method used to perform the test." /> <min value="0" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> </element> </differential> </StructureDefinition>