<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="NICE-MedicationAdministration" />
  <meta>
    <lastUpdated value="2023-10-26T14:21:03.563241+00:00" />
  </meta>
  <url value="https://fhir.stichting-nice.nl/STU3/StructureDefinition/NICE-MedicationAdministration-2022Q1" />
  <version value="0.0.1" />
  <name value="NICE-MedicationAdministration" />
  <title value="NICE-MedicationAdministration" />
  <status value="active" />
  <date value="2023-10-26T14:21:42.886+00:00" />
  <publisher value="NICE" />
  <contact>
    <name value="NICE" />
    <telecom>
      <system value="email" />
      <value value="vragen@stichting-nice.nl" />
    </telecom>
  </contact>
  <description value="This profile is for submitting data to the NICE related to the admission of medication. The NICE needs information regarding: &#xD;&#xA;- The date of administration &#xD;&#xA;- The route it was administered in &#xD;&#xA;- The dosage &#xD;&#xA;- The rate of administration" />
  <purpose value="This profile is used to submit medication administration related information to the Dutch National Intensive Care Evaluation (NICE). It was derived from the Nictiz Health and Care Information Model (HCIM; Dutch: Zorginformatiebouwsteen or ZIB) MedicationAdministration, 2017 release version 3.1" />
  <copyright value="CC0" />
  <fhirVersion value="3.0.2" />
  <mapping>
    <identity value="NICE-Datadictionary-MDS" />
    <uri value="https://www.stichting-nice.nl/dd/#528" />
    <name value="NICE-Datadictionary-MDS" />
    <comment value="The Minimal Data Set (MDS)" />
  </mapping>
  <mapping>
    <identity value="NICE-Datadictionary-SOFA" />
    <uri value="https://www.stichting-nice.nl/dd/#547" />
    <name value="NICE-Datadictionary-SOFA" />
    <comment value="The Sequential Organ Failure Assessment (SOFA) module" />
  </mapping>
  <mapping>
    <identity value="NICE-Datadictionary-Capacity" />
    <uri value="https://www.stichting-nice.nl/dd/#561" />
    <name value="NICE-Datadictionary-Capacity" />
    <comment value="The Patient Acuity Registration" />
  </mapping>
  <mapping>
    <identity value="NICE-Datadictionary-Sepsis" />
    <uri value="https://www.stichting-nice.nl/dd/#646" />
    <name value="NICE-Datadictionary-Sepsis" />
    <comment value="The Sepsis Registration Module" />
  </mapping>
  <kind value="resource" />
  <abstract value="false" />
  <type value="MedicationAdministration" />
  <baseDefinition value="http://nictiz.nl/fhir/StructureDefinition/zib-MedicationAdministration" />
  <derivation value="constraint" />
  <differential>
    <element id="MedicationAdministration">
      <path value="MedicationAdministration" />
      <definition value="Medication administration is the registration of the individual administrations of the medicine on the patient by the administrator (e.g. a nurse or patient themselves), in relation to the entered agreements.&#xD;&#xA;&#xD;&#xA;The NICE registration encompasses two types of data elements: (1) elements that require the amount of the administered product and (2) whether or not a specific kind of medication is administered to the patient. This profile can be used to submit both types." />
    </element>
    <element id="MedicationAdministration.extension">
      <path value="MedicationAdministration.extension" />
      <min value="2" />
    </element>
    <element id="MedicationAdministration.extension:ScoreDay">
      <path value="MedicationAdministration.extension" />
      <sliceName value="ScoreDay" />
      <definition value="Extension that is used to indicate the day of scoring. The first 24 hours after admission count as day 1. The next day starts from the first morning shift and lasts 24 hours, so until the start of the next morning shift. Note: Score day 1 can overlap with score day 2, and 'the first morning shift' is specified locally can differ between hospitals.&#xD;&#xA;&#xD;&#xA;ScoreDay SHALL be submitted if the instance is not about the historical use of the medication." />
      <type>
        <code value="Extension" />
        <profile value="https://fhir.stichting-nice.nl/STU3/StructureDefinition/NICE-ScoreDay-2022Q1" />
      </type>
    </element>
    <element id="MedicationAdministration.extension:Verified">
      <path value="MedicationAdministration.extension" />
      <sliceName value="Verified" />
      <short value="Is the instance validated by a medical professional?" />
      <definition value="Extension that is used to indicate whether the entire instance has been validated.&#xD;&#xA;&#xD;&#xA;Every instance shall be validated by a hospital member / datamanager. However, this is not always feasible in case of automated submission of NICE data elements. This extensions shall be used to indicate the validation status of the instance." />
      <type>
        <code value="Extension" />
        <profile value="https://fhir.stichting-nice.nl/STU3/StructureDefinition/NICE-Verified-2022Q1" />
      </type>
    </element>
    <element id="MedicationAdministration.dosage.route">
      <path value="MedicationAdministration.dosage.route" />
      <definition value="The route through which the medication is administered (oral, nasal, intravenous,...)&#xD;&#xA;&#xD;&#xA;The original Nictiz valueset describes that all values from the Dutch G-standaard (administration routes) can be submitted. However, NICE can only process the following codes (which is also due to the fact that NICE doens't have to know all specific administration routes):&#xD;&#xA;- Intraveneus (intravenous)&#xD;&#xA;- Intra-arterieel (Intra-arterial)&#xD;&#xA;- Oraal (Oral)&#xD;&#xA;- Niet ingevuld (Not registered)&#xD;&#xA;- Niet van toepassing (not applicable)" />
      <binding>
        <strength value="extensible" />
        <description value="MedicationAdministrationRouteCodeList" />
        <valueSetUri value="https://fhir.stichting-nice.nl/ValueSet/NICE-AdministrationRouteCodeList" />
      </binding>
      <mapping>
        <identity value="NICE-Datadictionary-MDS" />
        <map value="https://www.stichting-nice.nl/dd/#432" />
        <comment value="Vasoactive medication" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Capacity" />
        <map value="https://www.stichting-nice.nl/dd/#576" />
        <comment value="Administration of arterial medication" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Capacity" />
        <map value="https://www.stichting-nice.nl/dd/#572" />
        <comment value="Continuous intravenous administration of antiarrythmics" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Capacity" />
        <map value="https://www.stichting-nice.nl/dd/#599" />
        <comment value="Anticoagulation" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Capacity" />
        <map value="https://www.stichting-nice.nl/dd/#611" />
        <comment value="Nutrition - parenteral" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Capacity" />
        <map value="https://www.stichting-nice.nl/dd/#625" />
        <comment value="Antibiotics (IV)" />
      </mapping>
    </element>
    <element id="MedicationAdministration.dosage.dose">
      <path value="MedicationAdministration.dosage.dose" />
      <definition value="Amount of the administered product&#xD;&#xA;&#xD;&#xA;NOTE: NICE will not process exact dose values because they are not required to interpret the data dictionary elements. HOWEVER, when sending a MedicationAdministration record/instance this value shall NOT be 0 in order for NICE to process the instance. Otherwise the instance is marked as 'not administered'." />
    </element>
    <element id="MedicationAdministration.dosage.rate[x]">
      <path value="MedicationAdministration.dosage.rate[x]" />
      <definition value="The administering speed is used in slow administration of liquid. In practice, the measuring unit is almost always ml/hour. &#xD;&#xA;&#xD;&#xA;For example, with an administering speed of 10ml/hour: &#xD;&#xA;- amount = 10 (Ratio.numerator.Quantity.value)&#xD;&#xA;- dose unit = ml (Ratio.numerator.Quantity.unit)&#xD;&#xA;- time unit = hour (Ratio.denominator.Quantity.unit)&#xD;&#xA;&#xD;&#xA;**A hospital should only submit the highest dosage rate per ScoreDay as described in the data dictionary. Submission of multiple values will not be processed by NICE.**&#xD;&#xA;&#xD;&#xA;Submitting the administering speed is only relevant for the NICE elements that require administration dosage:&#xD;&#xA;- Highest dopamine speed (SOFA/Sepsis)&#xD;&#xA;- Highest adrenaline speed (SOFA/Sepsis)&#xD;&#xA;- Highest noradrenaline speed (SOFA/Sepsis)" />
      <constraint>
        <key value="valueExtremes" />
        <severity value="error" />
        <human value="Defines the lower bounds and upper bounds of the allowed values for Bodyheight" />
        <expression value="MedicationAdministration.dosage.rate.quantity &gt; 0.0 and MedicationAdministration.dosage.rate.quantity &lt; 100.0" />
      </constraint>
      <mapping>
        <identity value="NICE-Datadictionary-SOFA" />
        <map value="https://www.stichting-nice.nl/dd/#18" />
        <comment value="Highest adrenaline speed (SOFA)" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-SOFA" />
        <map value="https://www.stichting-nice.nl/dd/#224" />
        <comment value="Highest noradrenaline speed (SOFA)" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-SOFA" />
        <map value="https://www.stichting-nice.nl/dd/#94" />
        <comment value="Highest dopamine speed" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Sepsis" />
        <map value="https://www.stichting-nice.nl/dd/#740" />
        <comment value="Highest dopamine speed (Sepsis)" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Sepsis" />
        <map value="https://www.stichting-nice.nl/dd/#744" />
        <comment value="Highest adrenaline speed (Sepsis)" />
      </mapping>
      <mapping>
        <identity value="NICE-Datadictionary-Sepsis" />
        <map value="https://www.stichting-nice.nl/dd/#745" />
        <comment value="Highest noradrenaline speed (Sepsis)" />
      </mapping>
    </element>
  </differential>
</StructureDefinition>