{
  "resourceType": "StructureDefinition",
  "id": "mii-pr-biobank-specimen-core",
  "extension": [
    {
      "url": "https://www.medizininformatik-initiative.de/fhir/modul-meta/StructureDefinition/mii-ex-meta-license-codeable",
      "valueCodeableConcept": {
        "coding": [
          {
            "code": "CC-BY-4.0",
            "system": "http://hl7.org/fhir/spdx-license",
            "display": "Creative Commons Attribution 4.0 International"
          }
        ]
      }
    }
  ],
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore",
  "version": "2026.0.1",
  "name": "MII_PR_Biobank_Specimen_Bioprobe_Core",
  "_name": {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/translation",
        "extension": [
          {
            "url": "lang",
            "valueCode": "en-US"
          },
          {
            "url": "content",
            "valueString": "MII_PR_Biobank_Specimen_Bioprobe_Core"
          }
        ]
      }
    ]
  },
  "title": "MII PR Biobank Specimen Bioprobe Core",
  "_title": {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/translation",
        "extension": [
          {
            "url": "lang",
            "valueCode": "de-DE"
          },
          {
            "url": "content",
            "valueString": "Specimen Bioprobe Core"
          }
        ]
      },
      {
        "url": "http://hl7.org/fhir/StructureDefinition/translation",
        "extension": [
          {
            "url": "lang",
            "valueCode": "en-US"
          },
          {
            "url": "content",
            "valueString": "Specimen Bioprobe Core"
          }
        ]
      }
    ]
  },
  "status": "active",
  "date": "2025-09-02",
  "publisher": "Medizininformatik Initiative",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "https://www.medizininformatik-initiative.de"
        }
      ]
    }
  ],
  "description": "Basisiprofil zur Abbildung einer MII Bioprobe. Nicht zur direkten Implementierung gedacht, Module leiten bei Bedarf eigene Profile von diesem Profil ab.",
  "_description": {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/translation",
        "extension": [
          {
            "url": "lang",
            "valueCode": "de-DE"
          },
          {
            "url": "content",
            "valueString": "Basisiprofil zur Abbildung einer MII Bioprobe. Nicht zur direkten Implementierung gedacht, Module leiten bei Bedarf eigene Profile von diesem Profil ab."
          }
        ]
      },
      {
        "url": "http://hl7.org/fhir/StructureDefinition/translation",
        "extension": [
          {
            "url": "lang",
            "valueCode": "en-US"
          },
          {
            "url": "content",
            "valueString": "Base profile for representing a MII bioprobe. Not intended for direct implementation, modules derive their own profiles from this profile as needed."
          }
        ]
      }
    ]
  },
  "fhirVersion": "4.0.1",
  "kind": "resource",
  "abstract": false,
  "type": "Specimen",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Specimen",
  "derivation": "constraint",
  "differential": {
    "element": [
      {
        "id": "Specimen.id",
        "path": "Specimen.id",
        "mustSupport": true
      },
      {
        "id": "Specimen.meta",
        "path": "Specimen.meta",
        "mustSupport": true
      },
      {
        "id": "Specimen.meta.source",
        "path": "Specimen.meta.source",
        "mustSupport": true
      },
      {
        "id": "Specimen.meta.profile",
        "path": "Specimen.meta.profile",
        "mustSupport": true
      },
      {
        "id": "Specimen.extension:feature",
        "path": "Specimen.extension",
        "sliceName": "feature",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://hl7.org/fhir/5.0/StructureDefinition/extension-Specimen.feature"
            ]
          }
        ]
      },
      {
        "id": "Specimen.extension:probenebene",
        "path": "Specimen.extension",
        "sliceName": "probenebene",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-ebene"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Specimen.identifier",
        "path": "Specimen.identifier",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Proben-ID"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen ID"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Einrichtungsinterner Identifier der Probe."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Internal identifier of the specimen at the institution."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.status",
        "path": "Specimen.status",
        "min": 1,
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Verfügbarkeitsstatus"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Availability status"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Der Status der Probe in Bezug auf die Verfügbarkeit für Forschung."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The status of the specimen in terms of its availability for research."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.type",
        "path": "Specimen.type",
        "min": 1,
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Probenart"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen type"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Die Art der Probe, codiert in SNOMED CT."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The type of the specimen, encoded as SNOMED CT code."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.type.coding",
        "path": "Specimen.type.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "$this.system"
            }
          ],
          "rules": "open"
        },
        "min": 1
      },
      {
        "id": "Specimen.type.coding.system",
        "path": "Specimen.type.coding.system",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.type.coding.code",
        "path": "Specimen.type.coding.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.type.coding:sct",
        "path": "Specimen.type.coding",
        "sliceName": "sct",
        "min": 1,
        "max": "*",
        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/mii-vs-biobank-probenart-sct"
        }
      },
      {
        "id": "Specimen.type.coding:sct.system",
        "path": "Specimen.type.coding.system",
        "patternUri": "http://snomed.info/sct"
      },
      {
        "id": "Specimen.subject",
        "path": "Specimen.subject",
        "min": 1,
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient"
            ]
          }
        ],
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Patient:in"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Patient"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Verweis auf die Person, von der die Probe stammt."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Reference to the person from whom the specimen was collected."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.receivedTime",
        "path": "Specimen.receivedTime",
        "mustSupport": true
      },
      {
        "id": "Specimen.parent",
        "path": "Specimen.parent",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Ist gewonnen aus"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Derived from"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Referenz auf eine übergeordnete Probe, aus der diese Probe gewonnen wurde."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Reference to a parent specimen from which this specimen was derived."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.request",
        "path": "Specimen.request",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Entnahme-ID"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Collection ID"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Der Identifier der Probenentnahme."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The identifier for the specimen collection."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.collection",
        "path": "Specimen.collection",
        "min": 1,
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Probenentnahme"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen sampling"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Informationen über den Prozess der Probenentnahme, einschließlich Entnahmezeitpunkt und -stelle."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Information about the specimen collection process, including collection time and site."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.collection.extension:einstellungBlutversorgung",
        "path": "Specimen.collection.extension",
        "sliceName": "einstellungBlutversorgung",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/EinstellungBlutversorgung"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.collected[x]",
        "path": "Specimen.collection.collected[x]",
        "min": 1,
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Entnahmezeitpunkt"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Sampling time"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Der Zeitpunkt, zu dem die Probe entnommen oder gesammelt wurde."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The time when the specimen was collected or obtained."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.collection.quantity",
        "path": "Specimen.collection.quantity",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Probenmenge"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen quantity"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Die Menge des gesammelten Materials."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The amount of material collected."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.collection.quantity.extension:pqTranslation",
        "path": "Specimen.collection.quantity.extension",
        "sliceName": "pqTranslation",
        "min": 0,
        "max": "*",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/iso21090-PQ-translation"
            ]
          }
        ]
      },
      {
        "id": "Specimen.collection.quantity.extension:quantityPrecision",
        "path": "Specimen.collection.quantity.extension",
        "sliceName": "quantityPrecision",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "http://hl7.org/fhir/StructureDefinition/quantity-precision"
            ]
          }
        ]
      },
      {
        "id": "Specimen.collection.quantity.value",
        "path": "Specimen.collection.quantity.value",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.quantity.unit",
        "path": "Specimen.collection.quantity.unit",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.quantity.system",
        "path": "Specimen.collection.quantity.system",
        "min": 1,
        "patternUri": "http://unitsofmeasure.org",
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.quantity.code",
        "path": "Specimen.collection.quantity.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.bodySite",
        "path": "Specimen.collection.bodySite",
        "constraint": [
          {
            "key": "mii-bb-1",
            "severity": "error",
            "human": "Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.",
            "expression": "coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()",
            "source": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore"
          }
        ],
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Anatomische Lokalisation"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "anatomical localisation"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Die Körperstelle, von der die Probe entnommen wurde."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The body site from which the specimen was collected."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.collection.bodySite.coding",
        "path": "Specimen.collection.bodySite.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "$this.system"
            }
          ],
          "rules": "open"
        }
      },
      {
        "id": "Specimen.collection.bodySite.coding.system",
        "path": "Specimen.collection.bodySite.coding.system",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.bodySite.coding.code",
        "path": "Specimen.collection.bodySite.coding.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.bodySite.coding:sct",
        "path": "Specimen.collection.bodySite.coding",
        "sliceName": "sct",
        "min": 0,
        "max": "*",
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/mii-vs-biobank-body-structures-sct"
        }
      },
      {
        "id": "Specimen.collection.bodySite.coding:sct.system",
        "path": "Specimen.collection.bodySite.coding.system",
        "patternUri": "http://snomed.info/sct"
      },
      {
        "id": "Specimen.collection.bodySite.coding:icd-o-3",
        "path": "Specimen.collection.bodySite.coding",
        "sliceName": "icd-o-3",
        "min": 0,
        "max": "*",
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-icdo3-topographie"
        }
      },
      {
        "id": "Specimen.collection.bodySite.coding:icd-o-3.system",
        "path": "Specimen.collection.bodySite.coding.system",
        "patternUri": "http://terminology.hl7.org/CodeSystem/icd-o-3"
      },
      {
        "id": "Specimen.collection.fastingStatus[x]",
        "path": "Specimen.collection.fastingStatus[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Nüchternstatus"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Fasting status"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Der Nüchternstatus der Person zum Zeitpunkt der Probenentnahme."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The fasting status of the person at the time the specimen was collected."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.collection.fastingStatus[x]:fastingStatusCodeableConcept",
        "path": "Specimen.collection.fastingStatus[x]",
        "sliceName": "fastingStatusCodeableConcept",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://terminology.hl7.org/ValueSet/v2-0916"
        }
      },
      {
        "id": "Specimen.collection.fastingStatus[x]:fastingStatusCodeableConcept.coding.system",
        "path": "Specimen.collection.fastingStatus[x].coding.system",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.collection.fastingStatus[x]:fastingStatusCodeableConcept.coding.code",
        "path": "Specimen.collection.fastingStatus[x].coding.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.processing",
        "path": "Specimen.processing",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "$this.procedure"
            }
          ],
          "rules": "open"
        },
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Probenverarbeitung"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen processing"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Details zur Verarbeitung der Probe, einschließlich Prozeduren und Verarbeitungszeitraum."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Details about the processing of the specimen, including procedures and processing period."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.processing.extension",
        "path": "Specimen.processing.extension",
        "min": 1
      },
      {
        "id": "Specimen.processing.extension:temperaturbedingungen",
        "path": "Specimen.processing.extension",
        "sliceName": "temperaturbedingungen",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Specimen.processing.procedure",
        "path": "Specimen.processing.procedure",
        "min": 1,
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Verarbeitungstyp"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Processing procedure"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Die angewendete Prozedur zur Verarbeitung der Probe, z.B. Zentrifugation."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The procedure applied to process the specimen, e.g. centrifugation."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.processing.procedure.coding",
        "path": "Specimen.processing.procedure.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "$this.system"
            }
          ],
          "rules": "open"
        },
        "min": 1
      },
      {
        "id": "Specimen.processing.procedure.coding.system",
        "path": "Specimen.processing.procedure.coding.system",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.processing.procedure.coding.code",
        "path": "Specimen.processing.procedure.coding.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.processing.procedure.coding:sct",
        "path": "Specimen.processing.procedure.coding",
        "sliceName": "sct",
        "min": 1,
        "max": "*",
        "mustSupport": true,
        "binding": {
          "strength": "preferred",
          "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/mii-vs-biobank-laboratory-procedure-sct"
        }
      },
      {
        "id": "Specimen.processing.procedure.coding:sct.system",
        "path": "Specimen.processing.procedure.coding.system",
        "patternUri": "http://snomed.info/sct"
      },
      {
        "id": "Specimen.processing.additive",
        "path": "Specimen.processing.additive",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance"
            ]
          }
        ],
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Additive bei Verarbeitung"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Processing additives"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Zusatzstoffe, die während der Probenverarbeitung verwendet wurden, z.B. Fixierungsmittel."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Additives used during the specimen processing, e.g. fixatives."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.processing.time[x]",
        "path": "Specimen.processing.time[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "mustSupport": true
      },
      {
        "id": "Specimen.processing.time[x]:timePeriod",
        "path": "Specimen.processing.time[x]",
        "sliceName": "timePeriod",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Period"
          }
        ],
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Verarbeitungszeitraum"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Processing period"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Der Zeitraum, in dem die Probe verarbeitet wurde."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The time period during which the specimen was processed."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.processing.time[x]:timePeriod.start",
        "path": "Specimen.processing.time[x].start",
        "mustSupport": true
      },
      {
        "id": "Specimen.processing.time[x]:timePeriod.end",
        "path": "Specimen.processing.time[x].end",
        "mustSupport": true
      },
      {
        "id": "Specimen.processing:lagerprozess",
        "path": "Specimen.processing",
        "sliceName": "lagerprozess",
        "min": 0,
        "max": "*",
        "mustSupport": true
      },
      {
        "id": "Specimen.processing:lagerprozess.extension",
        "path": "Specimen.processing.extension",
        "mustSupport": true
      },
      {
        "id": "Specimen.processing:lagerprozess.extension:temperaturbedingungen",
        "path": "Specimen.processing.extension",
        "sliceName": "temperaturbedingungen",
        "min": 1,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Specimen.processing:lagerprozess.procedure",
        "path": "Specimen.processing.procedure",
        "min": 1,
        "patternCodeableConcept": {
          "coding": [
            {
              "code": "1186936003",
              "system": "http://snomed.info/sct"
            }
          ]
        }
      },
      {
        "id": "Specimen.processing:lagerprozess.time[x]",
        "path": "Specimen.processing.time[x]",
        "min": 1,
        "type": [
          {
            "code": "Period"
          }
        ]
      },
      {
        "id": "Specimen.processing:lagerprozess.time[x]:timePeriod",
        "path": "Specimen.processing.time[x]",
        "sliceName": "timePeriod",
        "min": 1,
        "type": [
          {
            "code": "Period"
          }
        ]
      },
      {
        "id": "Specimen.processing:lagerprozess.time[x]:timePeriod.start",
        "path": "Specimen.processing.time[x].start",
        "min": 1
      },
      {
        "id": "Specimen.container",
        "path": "Specimen.container",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Probenbehältnis"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen container"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Informationen über den Behälter, in dem die Probe aufbewahrt wird."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Information about the container in which the specimen is stored."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.container.type",
        "path": "Specimen.container.type",
        "min": 1,
        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/mii-vs-biobank-containertyp-sct"
        },
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Containertyp"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Container type"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Der Typ des Probencontainers, der für diese Probe verwendet wurde."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The type of container used for this specimen."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.container.type.coding.system",
        "path": "Specimen.container.type.coding.system",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.type.coding.code",
        "path": "Specimen.container.type.coding.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.capacity",
        "path": "Specimen.container.capacity",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Containerkapazität"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Capacity"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Die maximale Kapazität des Containers, der für die Probe verwendet wurde."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The maximum capacity of the container used for the specimen."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.container.capacity.value",
        "path": "Specimen.container.capacity.value",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.capacity.unit",
        "path": "Specimen.container.capacity.unit",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.capacity.system",
        "path": "Specimen.container.capacity.system",
        "min": 1,
        "patternUri": "http://unitsofmeasure.org",
        "mustSupport": true
      },
      {
        "id": "Specimen.container.capacity.code",
        "path": "Specimen.container.capacity.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.specimenQuantity",
        "path": "Specimen.container.specimenQuantity",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Probenmenge"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Specimen quantity"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Die Menge des vorhandenen Materials."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "The amount of material available."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.container.specimenQuantity.value",
        "path": "Specimen.container.specimenQuantity.value",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.specimenQuantity.unit",
        "path": "Specimen.container.specimenQuantity.unit",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.specimenQuantity.system",
        "path": "Specimen.container.specimenQuantity.system",
        "min": 1,
        "patternUri": "http://unitsofmeasure.org",
        "mustSupport": true
      },
      {
        "id": "Specimen.container.specimenQuantity.code",
        "path": "Specimen.container.specimenQuantity.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Specimen.container.additive[x]",
        "path": "Specimen.container.additive[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Additiv"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Additives"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Zusatzstoffe, die im Probenbehälter enthalten sind z.B. wie Konservierungsmittel."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Additives contained in the specimen container e.g. preservatives."
                }
              ]
            }
          ]
        }
      },
      {
        "id": "Specimen.container.additive[x]:additiveReference",
        "path": "Specimen.container.additive[x]",
        "sliceName": "additiveReference",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance"
            ]
          }
        ]
      },
      {
        "id": "Specimen.note",
        "path": "Specimen.note",
        "mustSupport": true,
        "_short": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Projektnutzung"
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Project usage"
                }
              ]
            }
          ]
        },
        "_definition": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "de-DE"
                },
                {
                  "url": "content",
                  "valueString": "Freitextangabe zur Verwendung der Probe in spezifischen Projekten."
                }
              ]
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/translation",
              "extension": [
                {
                  "url": "lang",
                  "valueCode": "en-US"
                },
                {
                  "url": "content",
                  "valueString": "Free-text information about the use of the specimen in specific projects."
                }
              ]
            }
          ]
        }
      }
    ]
  }
}