<status value="active" /> <publisher value="Nictiz" /> <contact> <name value="Nictiz" /> <telecom> <system value="url" /> <value value="https://www.nictiz.nl" /> <use value="work" /> </telecom> </contact> <description value="Instructions for the use or administration of the medication, e.g. dose and route of administration. In the medication building block MedicationUse, this is the pattern of use established by the patient or which the patient followed." /> <purpose value="This Dosage data type profile _mainly_ represents the DosingInstructions concept of the sub building block InstructionsForUse, for implementations following the information standard [MP9](https://informatiestandaarden.nictiz.nl/wiki/Landingspagina_Medicatieproces). This profile is based on the Dutch zib ('Zorginformatiebouwsteen', i.e. Health and Care Information Model) InstructionsForUse, but has no dependency on the corresponding nl-core profile because it contains non-compatible changes. Where compatible, mappings to zib concepts are defined. Additional concepts or concepts that are not compatible with their zib counterparts contain a mapping to the MP9 data set. This profile also includes the concepts AdditionalInstructions and RouteOfAdministration. These concepts are placed on the same level as DosingInstructions in the zib, but are in FHIR part of the Dosage data type. As a consequence, these concepts may be duplicated if this Dosage profile is instantiated multiple times. This profile should be used in medication related resources that define dosage instructions and supplemented by the extensions [ext-RenderedDosageInstruction](http://nictiz.nl/fhir/StructureDefinition/ext-RenderedDosageInstruction) and [ext-InstructionsForUse.RepeatPeriodCyclicalSchedule](http://nictiz.nl/fhir/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule) to implement the remaining concepts Description and RepeatPeriodCyclicalSchedule." /> <copyright value="Copyright and related rights waived via CC0, https://creativecommons.org/publicdomain/zero/1.0/. This does not apply to information from third parties, for example a medical terminology system. The implementer alone is responsible for identifying and obtaining any necessary licenses or authorizations to utilize third party IP in connection with the specification or otherwise." /> <fhirVersion value="4.0.1" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <uri value="https://zibs.nl/wiki/InstructionsForUse-v1.2.1(2020EN)" /> <name value="zib InstructionsForUse-v1.2.1(2020EN)" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <uri value="https://zibs.nl/wiki/Range-v1.0.1(2020EN)" /> <name value="zib Range-v1.0.1(2020EN)" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <uri value="https://decor.nictiz.nl/pub/medicatieproces/mp-html-20250522T132618/ds-2.16.840.1.113883.2.4.3.11.60.20.77.1.4-2022-06-30T000000.html" /> <name value="ART-DECOR Dataset MP9 3.0.0-rc.1 20250522" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <uri value="https://decor.nictiz.nl/pub/medicatieproces/mp-html-20260213T112547/ds-2.16.840.1.113883.2.4.3.11.60.20.77.1.4-2022-06-30T000000.html" /> <name value="ART-DECOR Dataset MP9 3.0.0-rc.2 20260213" /> </mapping> <kind value="complex-type" /> <abstract value="false" /> <type value="Dosage" /> <baseDefinition value="http://hl7.org/fhir/StructureDefinition/Dosage" /> <derivation value="constraint" /> <snapshot> <element id="Dosage"> <path value="Dosage" /> <short value="DosingInstructions" /> <definition value="Indicates how the medication is/was taken or should be taken by the patient. Instructions for the administrator to administer the medication (the patient themselves, a nurse or other aid). When taking stock of medication use, the dosage describes the pattern of use established by the patient." /> <comment value="This element _mostly_ represents the DosingInstructions container from zib InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are **duplicated** in every repetition of this element, even though these concepts should be present just once according to the zib. This element does not contain a mapping to the Dosage container from zib InstructionsForUse. However, all child concepts of the Dosage concept are mapped. If an instance of zib container DosingInstructions contains multiple Dosage containers, each of these results in a separate instance of the FHIR Dosage data type conforming to this profile, wherein `.sequence` (zib concept SequenceNumber) and `.timing.repeat.bounds[x]:boundsDuration` (zib concept DoseDuration) are equal." /> <alias value="Doseerinstructie" /> <min value="0" /> <max value="*" /> <base> <path value="Dosage" /> <min value="0" /> <max value="*" /> </base> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value=".outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT]" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.22095" /> <comment value="DosingInstructions" /> </mapping> </element> <element id="Dosage.id"> <path value="Dosage.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.extension"> <path value="Dosage.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.extension:asNeeded"> <path value="Dosage.extension" /> <sliceName value="asNeeded" /> <short value="Optional Extensions Element" /> <definition value="Pre-adopt from FHIR R5 of the `Dosage.asNeededFor` element." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/ext-Dosage-AsNeededFor" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.extension:asNeeded.id"> <path value="Dosage.extension.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.extension:asNeeded.extension"> <path value="Dosage.extension.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.extension:asNeeded.url"> <path value="Dosage.extension.url" /> <representation value="xmlAttr" /> <short value="identifies the meaning of the extension" /> <definition value="Source of the definition for the extension code - a logical name or a URL." /> <comment value="The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension." /> <min value="1" /> <max value="1" /> <base> <path value="Extension.url" /> <min value="1" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="uri" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <fixedUri value="http://nictiz.nl/fhir/StructureDefinition/ext-Dosage-AsNeededFor" /> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.extension:asNeeded.value[x]"> <path value="Dosage.extension.value[x]" /> <short value="Condition" /> <definition value="The condition for administering medication can be: * a physiological measurement value (plasma glucose concentration, body temperature, blood pressure); * a symptom or other circumstance (in the event of a headache, or itch). Supplemental information from G-standard bst362 make up the list of values for coded entering of this concept. Also always include the textual description of that code. Physiological measurement values or other conditions that do not occur in bst362 do not need to be coded. These can be expressed in free text in the Description concept." /> <comment value="If only one 'asNeeded' concept is exchanged within a Dosage, use `Dosage.asNeeded[x]`. This extension is only used when multiple 'asNeeded' concepts are to be exchanged." /> <alias value="Criterium" /> <min value="0" /> <max value="1" /> <base> <path value="Extension.value[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <binding> <strength value="required" /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19945" /> <comment value="Condition" /> </mapping> </element> <element id="Dosage.modifierExtension"> <path value="Dosage.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.sequence"> <path value="Dosage.sequence" /> <short value="SequenceNumber" /> <definition value="This indicates the sequence of the dosing instructions within the medication agreement." /> <comment value="32 bit number; for values larger than this, use decimal" /> <requirements value="If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent. If the sequence number is different, then the Dosages are intended to be sequential." /> <alias value="Volgnummer" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.sequence" /> <min value="0" /> <max value="1" /> </base> <type> <code value="integer" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="TQ1-1" /> </mapping> <mapping> <identity value="rim" /> <map value=".text" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.22503" /> <comment value="SequenceNumber" /> </mapping> </element> <element id="Dosage.text"> <path value="Dosage.text" /> <short value="Free text dosage instructions e.g. SIG" /> <definition value="Free text dosage instructions e.g. SIG." /> <comment value="Note that FHIR strings SHALL NOT exceed 1MB in size" /> <requirements value="Free text dosage instructions can be used for cases where the instructions are too complex to code. The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated. If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing. Additional information about administration or preparation of the medication should be included as text." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.text" /> <min value="0" /> <max value="1" /> </base> <type> <code value="string" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-6; RXE-21" /> </mapping> <mapping> <identity value="rim" /> <map value=".text" /> </mapping> </element> <element id="Dosage.additionalInstruction"> <path value="Dosage.additionalInstruction" /> <short value="AdditionalInstructions" /> <definition value="The additional instructions contain extra information on the use of the current prescription. The additional instructions applies to the entire instructions for use and not to an individual dosage. This includes all instructions for use. The text can come from the original “paper" medication prescription, but can also be generated from the coded information. The instructions may not conflict with other components of the medication agreement/ administration agreement. The instructions can also refer to an existing protocol. In the case of an external dosing regimen (e.g., "according to thrombosis service regimen"), OTH is used. The texts in the G-standard that can support this attribute are included in table 362 where the texts from the general practitioner' standard 'NHG-Tabel 25-component b: 'aanvullende teksten’ ' are included. These texts can only be used when it is not possible to include this information in the other structured elements of the Instructions for Use. A free-text explanation of the Instructions for Use can be placed under code OTH if it is not possible to record it in a structured manner within the Instructions for Use." /> <comment value="Please note that in contrast to the zib, this AdditionalInstructions concept is grouped under the DosingInstructions concept. This `.additionalInstruction` element shall have the same value when there are multiple DosingInstructions." /> <requirements value="Additional instruction is intended to be coded, but where no code exists, the element could include text. For example, "Swallow with plenty of water" which might or might not be coded." /> <alias value="AanvullendeInstructie" /> <min value="0" /> <max value="*" /> <base> <path value="Dosage.additionalInstruction" /> <min value="0" /> <max value="*" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="AdditionalInstruction" /> </extension> <strength value="required" /> <description value="WCIAv3 Tabel 25 B-codes subset voor aanvullende gebruiksinstructies" /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.20.77.11.9--20160407000000" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-7" /> </mapping> <mapping> <identity value="rim" /> <map value=".text" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-51" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-51" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-649" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-649" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-300" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-300" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-368" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-368" /> <comment value="AdditionalInstructions" /> </mapping> </element> <element id="Dosage.patientInstruction"> <path value="Dosage.patientInstruction" /> <short value="Patient or consumer oriented instructions" /> <definition value="Instructions in terms that are understood by the patient or consumer." /> <comment value="Note that FHIR strings SHALL NOT exceed 1MB in size" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.patientInstruction" /> <min value="0" /> <max value="1" /> </base> <type> <code value="string" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-7" /> </mapping> <mapping> <identity value="rim" /> <map value=".text" /> </mapping> </element> <element id="Dosage.timing"> <path value="Dosage.timing" /> <short value="AdministeringSchedule" /> <definition value="Specifications of the times at which the medication is to be administered. This is indicated as follows: * Time(s) (16:00) or indications (“before meals”) at which the medication is to be taken each day. * A specific number of times the medication is to be taken each day ("3x a day"), indicated with the frequency. * A time interval between consecutive doses (“Every 2 hours”, “every 3 days”), indicated with the word Interval. * Combined periods with an interval and duration (“1 daily for three out of four weeks: the pill schedule”) If a certain medication is not to be taken daily, the aforementioned can be combined with daily indications: * One or more week days on which the medication is to be administered (e.g. “Monday, Wednesday, Friday”) * ”3x a week”, “2x a month”. The specified administration “infinite” is automatically to be repeated until: * The end date and time has been reached * The total administration duration has been reached (14 days) * A specific amount of administrations has been reached (“20 doses”), to be entered in the Frequency concept." /> <comment value="This attribute might not always be populated while the Dosage.text is expected to be populated. If both are populated, then the Dosage.text should reflect the content of the Dosage.timing." /> <requirements value="The timing schedule for giving the medication to the patient. This data type allows many different expressions. For example: "Every 8 hours"; "Three times a day"; "1/2 an hour before breakfast for 10 days from 23-Dec 2011:"; "15 Oct 2013, 17 Oct 2013 and 1 Nov 2013". Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period." /> <alias value="Toedieningsschema" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.timing" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Timing" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="N/A" /> </mapping> <mapping> <identity value="rim" /> <map value="QSET<TS> (GTS)" /> </mapping> <mapping> <identity value="rim" /> <map value=".effectiveTime" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19948" /> <comment value="AdministeringSchedule" /> </mapping> </element> <element id="Dosage.timing.id"> <path value="Dosage.timing.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.timing.extension"> <path value="Dosage.timing.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.timing.modifierExtension"> <path value="Dosage.timing.modifierExtension" /> <short value="Extensions that cannot be ignored even if unrecognized" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension)." /> <alias value="extensions" /> <alias value="user content" /> <alias value="modifiers" /> <min value="0" /> <max value="*" /> <base> <path value="BackboneElement.modifierExtension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <isModifier value="true" /> <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.timing.event"> <path value="Dosage.timing.event" /> <short value="When the event occurs" /> <definition value="Identifies specific times when the event occurs." /> <requirements value="In a Medication Administration Record, for instance, you need to take a general specification, and turn it into a precise specification." /> <min value="0" /> <max value="*" /> <base> <path value="Timing.event" /> <min value="0" /> <max value="*" /> </base> <type> <code value="dateTime" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="QLIST<TS>" /> </mapping> </element> <element id="Dosage.timing.repeat"> <path value="Dosage.timing.repeat" /> <short value="When the event is to occur" /> <definition value="A set of rules that describe when the event is scheduled." /> <requirements value="Many timing schedules are determined by regular repetitions." /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Element" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="tim-9" /> <severity value="error" /> <human value="If there's an offset, there must be a when (and not C, CM, CD, CV)" /> <expression value="offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))" /> <xpath value="not(exists(f:offset)) or exists(f:when)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-5" /> <severity value="error" /> <human value="period SHALL be a non-negative value" /> <expression value="period.exists() implies period >= 0" /> <xpath value="f:period/@value >= 0 or not(f:period/@value)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-6" /> <severity value="error" /> <human value="If there's a periodMax, there must be a period" /> <expression value="periodMax.empty() or period.exists()" /> <xpath value="not(exists(f:periodMax)) or exists(f:period)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-7" /> <severity value="error" /> <human value="If there's a durationMax, there must be a duration" /> <expression value="durationMax.empty() or duration.exists()" /> <xpath value="not(exists(f:durationMax)) or exists(f:duration)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-8" /> <severity value="error" /> <human value="If there's a countMax, there must be a count" /> <expression value="countMax.empty() or count.exists()" /> <xpath value="not(exists(f:countMax)) or exists(f:count)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-1" /> <severity value="error" /> <human value="if there's a duration, there needs to be duration units" /> <expression value="duration.empty() or durationUnit.exists()" /> <xpath value="not(exists(f:duration)) or exists(f:durationUnit)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-10" /> <severity value="error" /> <human value="If there's a timeOfDay, there cannot be a when, or vice versa" /> <expression value="timeOfDay.empty() or when.empty()" /> <xpath value="not(exists(f:timeOfDay)) or not(exists(f:when))" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-2" /> <severity value="error" /> <human value="if there's a period, there needs to be period units" /> <expression value="period.empty() or periodUnit.exists()" /> <xpath value="not(exists(f:period)) or exists(f:periodUnit)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <constraint> <key value="tim-4" /> <severity value="error" /> <human value="duration SHALL be a non-negative value" /> <expression value="duration.exists() implies duration >= 0" /> <xpath value="f:duration/@value >= 0 or not(f:duration/@value)" /> <source value="http://hl7.org/fhir/StructureDefinition/Timing" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="Implies PIVL or EIVL" /> </mapping> </element> <element id="Dosage.timing.repeat.id"> <path value="Dosage.timing.repeat.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.timing.repeat.extension"> <path value="Dosage.timing.repeat.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.timing.repeat.extension:timingExact"> <path value="Dosage.timing.repeat.extension" /> <sliceName value="timingExact" /> <short value="Whether specified times must be followed as closely as possible" /> <definition value="If true, indicates that the specified times, frequencies, periods are expected to be adhered to as precisely as possible. If false, indicates that a typical degree of variability based on institutional and/or patient convenience is acceptable." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="1" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> <profile value="http://hl7.org/fhir/StructureDefinition/timing-exact" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> <mapping> <identity value="v2" /> <map value="N/A" /> </mapping> <mapping> <identity value="rim" /> <map value="GTS.IsFlexible" /> </mapping> </element> <element id="Dosage.timing.repeat.extension:timingExact.id"> <path value="Dosage.timing.repeat.extension.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.timing.repeat.extension:timingExact.extension"> <path value="Dosage.timing.repeat.extension.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="0" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.timing.repeat.extension:timingExact.url"> <path value="Dosage.timing.repeat.extension.url" /> <representation value="xmlAttr" /> <short value="identifies the meaning of the extension" /> <definition value="Source of the definition for the extension code - a logical name or a URL." /> <comment value="The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension." /> <min value="1" /> <max value="1" /> <base> <path value="Extension.url" /> <min value="1" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="uri" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <fixedUri value="http://hl7.org/fhir/StructureDefinition/timing-exact" /> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.timing.repeat.extension:timingExact.value[x]"> <path value="Dosage.timing.repeat.extension.value[x]" /> <short value="Value of extension" /> <definition value="Indicates that the timing as specified by `.frequency`, `.period` and `.periodUnit` should be strictly interpreted. This is the case when the zib concept Interval is expressed using these elements (as opposed to the zib concept Frequency). The times can be chosen freely, but distribution throughout the day is more precise, and the interval between times is important (e.g. in the case of antibiotics). In the case of Baxter packs and intramural care, such a prescription is used to draw up a (location-specific) outline for distribution times (logistics)." /> <comment value="Notes on the zib concepts Frequency and Interval: 1. An interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period` and `.periodUnit`. However, the zib differentiates between the two concepts in the timing precision (the Interval concept defines precise intervals while the Frequency concept defines approximate intervals). When the interval is precise, this is communicated using the extension in `.extension:timingExact`. 2. On the other hand, the zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element. 3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated. In summary: * zib concept Frequency: * With time unit: * Nominal value: `.frequency`, `.period` and `.periodUnit` * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit` * Without time unit: * Nominal value: `.count` * Range: `.count` and `.countMax` * zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit` and `.extension:timingExact` (set to _true_)" /> <min value="1" /> <max value="1" /> <base> <path value="Extension.value[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="boolean" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval (implicit, main mapping is on `.frequency`, `.period` and `.periodMax`)" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-271" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-271" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-672" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-672" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-580" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-580" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-412" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-412" /> <comment value="(negative of) IsFlexible" /> </mapping> </element> <element id="Dosage.timing.repeat.bounds[x]"> <path value="Dosage.timing.repeat.bounds[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> <short value="Length/Range of lengths, or (Start and/or end) limits" /> <definition value="Either a duration for the length of the timing schedule, a range of possible length, or outer bounds for start and/or end limits of the timing schedule." /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.bounds[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Duration" /> </type> <type> <code value="Range" /> </type> <type> <code value="Period" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="IVL(TS) used in a QSI" /> </mapping> </element> <element id="Dosage.timing.repeat.bounds[x]:boundsDuration"> <path value="Dosage.timing.repeat.bounds[x]" /> <sliceName value="boundsDuration" /> <short value="DoseDuration" /> <definition value="The intended time duration for these dosing instructions, e.g. 5 days or 8 weeks. In the case of medication for an indefinite period, the dosing duration is left empty in the last dosing instruction." /> <alias value="Doseerduur" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.bounds[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Duration" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="IVL(TS) used in a QSI" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.22506" /> <comment value="DoseDuration" /> </mapping> </element> <element id="Dosage.timing.repeat.count"> <path value="Dosage.timing.repeat.count" /> <short value="Frequency / minimumValue / nominalValue" /> <definition value="Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by this `.count` element and optionally `.countMax` if a range should be represented." /> <comment value="Notes on the zib concept Frequency can be found in the comment of the `.frequency` element." /> <requirements value="Repetitions may be limited by end time or total occurrences." /> <alias value="Frequentie" /> <alias value="nominaleWaarde" /> <alias value="minimumWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.count" /> <min value="0" /> <max value="1" /> </base> <type> <code value="positiveInt" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.count" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency (single use only)" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> </element> <element id="Dosage.timing.repeat.countMax"> <path value="Dosage.timing.repeat.countMax" /> <short value="Frequency / maximumValue" /> <definition value="Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by the `.count` element and optionally `.countMax` if a range should be represented." /> <comment value="Notes on the zib concept Frequency can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="maximumWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.countMax" /> <min value="0" /> <max value="1" /> </base> <type> <code value="positiveInt" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.count" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.timing.repeat.duration"> <path value="Dosage.timing.repeat.duration" /> <short value="DurationOfAdministration" /> <definition value="The duration of administration defines the length of time during which the drug is administered and is mainly used in the slow parenteral administration of fluids. The `durationUnit` defines the time unit." /> <comment value="For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise)." /> <requirements value="Some activities are not instantaneous and need to be maintained for a period of time." /> <alias value="Toedieningsduur" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.duration" /> <min value="0" /> <max value="1" /> </base> <type> <code value="decimal" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.23141" /> <comment value="DurationOfAdministration" /> </mapping> </element> <element id="Dosage.timing.repeat.durationMax"> <path value="Dosage.timing.repeat.durationMax" /> <short value="How long when it happens (Max)" /> <definition value="If present, indicates that the duration is a range - so to perform the action between [duration] and [durationMax] time length." /> <comment value="For some events the duration is part of the definition of the event (e.g. IV infusions, where the duration is implicit in the specified quantity and rate). For others, it's part of the timing specification (e.g. exercise)." /> <requirements value="Some activities are not instantaneous and need to be maintained for a period of time." /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.durationMax" /> <min value="0" /> <max value="1" /> </base> <type> <code value="decimal" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase" /> </mapping> </element> <element id="Dosage.timing.repeat.durationUnit"> <path value="Dosage.timing.repeat.durationUnit" /> <short value="DurationOfAdministration" /> <definition value="The units of time, in UCUM units, for the duration of administration of time during which the drug is administered." /> <comment value="Note that FHIR strings SHALL NOT exceed 1MB in size" /> <alias value="Toedieningsduur" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.durationUnit" /> <min value="0" /> <max value="1" /> </base> <type> <code value="code" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="UnitsOfTime" /> </extension> <strength value="required" /> <description value="A unit of time (units from UCUM)." /> <valueSet value="http://hl7.org/fhir/ValueSet/units-of-time|4.0.1" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase.unit" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.23141" /> <comment value="DurationOfAdministration" /> </mapping> </element> <element id="Dosage.timing.repeat.frequency"> <path value="Dosage.timing.repeat.frequency" /> <short value="Frequency / minimumValue / nominalValue / Interval" /> <definition value="The `.frequency` element indicates either the number of dose moments per time unit (zib concept Frequency) or the time between dose times (zib concept Interval). If `.frequencyMax` is present, this `.frequency` element indicates the lower bound of the allowed range of the frequency." /> <comment value="Notes on the zib concepts Frequency and Interval, The zib differentiates between the two concepts in the specific usage of the extension `.extension:timingExact` and the element `.timeOfDay` combined: 1. The zib Interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period`, `.periodUnit`, the extension `.extension:timingExact` set to _true_ and the absence of the element `.timeOfDay`. 2. The zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element. 3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. The extension `.extension:timingExact` can be used to specify the precision of the timing of the administration (i.e. the element `.timeOfDay`). When this element is meant to convey the zib Frequency concept this can be, unlike the zib concept Interval, either _true_or _false_. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events as mentioned in the second point. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated. In summary: * zib concept Frequency: * With time unit (precision of the timing can be further specified with the extension `.extension:timingExact`): * Nominal value: `.frequency`, `.period` and `.periodUnit` * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit` * Without time unit: * Nominal value: `.count` * Range: `.count` and `.countMax` * zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit`, `.extension:timingExact` (SHALL be set to _true_) and the absence of `.timeOfDay`." /> <alias value="Frequentie" /> <alias value="minimumWaarde" /> <alias value="nominaleWaarde" /> <alias value="Interval" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.frequency" /> <min value="0" /> <max value="1" /> </base> <type> <code value="positiveInt" /> </type> <meaningWhenMissing value="If no frequency is stated, the assumption is that the event occurs once per period, but systems SHOULD always be specific about this" /> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval" /> </mapping> </element> <element id="Dosage.timing.repeat.frequencyMax"> <path value="Dosage.timing.repeat.frequencyMax" /> <short value="Frequency / maximumValue" /> <definition value="If present, indicates that the frequency is a range - so to repeat between [frequency] and [frequencyMax] times within the period or period range." /> <comment value="Notes on the zib concept Frequency can be found in the comment of the `.frequency` element." /> <alias value="maximumWaarde" /> <alias value="Frequentie" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.frequencyMax" /> <min value="0" /> <max value="1" /> </base> <type> <code value="positiveInt" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.timing.repeat.period"> <path value="Dosage.timing.repeat.period" /> <short value="Frequency / Interval" /> <definition value="Indicates the duration of time over which repetitions are to occur; e.g. to express "3 times per day", 3 would be the frequency and "1 day" would be the period. If `.periodMax` is present, this element indicates the lower bound of the allowed range of the period length." /> <comment value="Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="Interval" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.period" /> <min value="0" /> <max value="1" /> </base> <type> <code value="decimal" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval" /> </mapping> </element> <element id="Dosage.timing.repeat.periodMax"> <path value="Dosage.timing.repeat.periodMax" /> <short value="Upper limit of period (3-4 hours)" /> <definition value="If present, indicates that the period is a range from [period] to [periodMax], allowing expressing concepts such as "do this once every 3-5 days." /> <comment value="Do not use an IEEE type floating point type, instead use something that works like a true decimal, with inbuilt precision (e.g. Java BigInteger)" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.periodMax" /> <min value="0" /> <max value="1" /> </base> <type> <code value="decimal" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase" /> </mapping> </element> <element id="Dosage.timing.repeat.periodUnit"> <path value="Dosage.timing.repeat.periodUnit" /> <short value="Frequency / Interval" /> <definition value="The units of time for the period in UCUM units for Frequency and Interval." /> <comment value="Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="Interval" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.periodUnit" /> <min value="0" /> <max value="1" /> </base> <type> <code value="code" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="UnitsOfTime" /> </extension> <strength value="required" /> <description value="A unit of time (units from UCUM)." /> <valueSet value="http://hl7.org/fhir/ValueSet/units-of-time|4.0.1" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="PIVL.phase.unit" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency. When frequency is used, set `.extension.timingExact` to false." /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval" /> </mapping> </element> <element id="Dosage.timing.repeat.dayOfWeek"> <path value="Dosage.timing.repeat.dayOfWeek" /> <short value="WeekDay" /> <definition value="WeekDay indicates a pattern of doses on fixed week days." /> <comment value="If no days are specified, the action is assumed to happen every day as otherwise specified." /> <alias value="Weekdag" /> <min value="0" /> <max value="*" /> <base> <path value="Timing.repeat.dayOfWeek" /> <min value="0" /> <max value="*" /> </base> <type> <code value="code" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="DayOfWeek" /> </extension> <strength value="required" /> <description value="Use ConceptMap 'WeekdagCodelijst_to_DaysOfWeek' to translate zib terminology to profile terminology in ValueSet 'DaysOfWeek'" /> <valueSet value="http://hl7.org/fhir/ValueSet/days-of-week|4.0.1"> <extension url="http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap"> <valueCanonical value="http://nictiz.nl/fhir/ConceptMap/WeekdagCodelijst-to-DaysOfWeek" /> </extension> </valueSet> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19952" /> <comment value="WeekDay" /> </mapping> </element> <element id="Dosage.timing.repeat.timeOfDay"> <path value="Dosage.timing.repeat.timeOfDay" /> <short value="AdministrationTime" /> <definition value="The time of administration is a specific time of day (on the clock). This time usually isn’t (intended to be) exact. There can be multiple administering times in one day. The ideal time of administration can also be entered as a time of day (morning, afternoon, evening, night-time). The administration time is then to be left empty, and the time of day can be entered in the TimeOfDay concept." /> <comment value="If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa." /> <alias value="Toedientijd" /> <min value="0" /> <max value="*" /> <base> <path value="Timing.repeat.timeOfDay" /> <min value="0" /> <max value="*" /> </base> <type> <code value="time" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19951" /> <comment value="AdministrationTime" /> </mapping> </element> <element id="Dosage.timing.repeat.when"> <path value="Dosage.timing.repeat.when" /> <short value="TimeOfDay" /> <definition value="Time of day: morning, afternoon, evening, night." /> <comment value="If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa." /> <requirements value="Timings are frequently determined by occurrences such as waking, eating and sleep." /> <alias value="Dagdeel" /> <min value="0" /> <max value="*" /> <base> <path value="Timing.repeat.when" /> <min value="0" /> <max value="*" /> </base> <type> <code value="code" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="EventTiming" /> </extension> <strength value="required" /> <description value="Use ConceptMap 'DagdeelCodelijst_to_EventTiming' to translate zib terminology to profile terminology in ValueSet 'EventTiming'" /> <valueSet value="http://hl7.org/fhir/ValueSet/event-timing"> <extension url="http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap"> <valueCanonical value="http://nictiz.nl/fhir/ConceptMap/DagdeelCodelijst-to-EventTiming" /> </extension> </valueSet> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="EIVL.event" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19953" /> <comment value="TimeOfDay" /> </mapping> </element> <element id="Dosage.timing.repeat.offset"> <path value="Dosage.timing.repeat.offset" /> <short value="Minutes from event (before or after)" /> <definition value="The number of minutes from the event. If the event code does not indicate whether the minutes is before or after the event, then the offset is assumed to be after the event." /> <comment value="32 bit number; for values larger than this, use decimal" /> <min value="0" /> <max value="1" /> <base> <path value="Timing.repeat.offset" /> <min value="0" /> <max value="1" /> </base> <type> <code value="unsignedInt" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="EIVL.offset" /> </mapping> </element> <element id="Dosage.timing.code"> <path value="Dosage.timing.code" /> <short value="BID | TID | QID | AM | PM | QD | QOD | +" /> <definition value="A code for the timing schedule (or just text in code.text). Some codes such as BID are ubiquitous, but many institutions define their own additional codes. If a code is provided, the code is understood to be a complete statement of whatever is specified in the structured timing data, and either the code or the data may be used to interpret the Timing, with the exception that .repeat.bounds still applies over the code (and is not contained in the code)." /> <comment value="BID etc. are defined as 'at institutionally specified times'. For example, an institution may choose that BID is "always at 7am and 6pm". If it is inappropriate for this choice to be made, the code BID should not be used. Instead, a distinct organization-specific code should be used in place of the HL7-defined BID code and/or a structured representation should be used (in this case, specifying the two event times)." /> <min value="0" /> <max value="1" /> <base> <path value="Timing.code" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="TimingAbbreviation" /> </extension> <strength value="preferred" /> <description value="Code for a known / defined timing pattern." /> <valueSet value="http://hl7.org/fhir/ValueSet/timing-abbreviation" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> <mapping> <identity value="rim" /> <map value="QSC.code" /> </mapping> </element> <element id="Dosage.asNeeded[x]"> <path value="Dosage.asNeeded[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> <short value="Take "as needed" (for x)" /> <definition value="Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept)." /> <comment value="Can express "as needed" without a reason by setting the Boolean = True. In this case the CodeableConcept is not populated. Or you can express "as needed" with a reason by including the CodeableConcept. In this case the Boolean is assumed to be True. If you set the Boolean to False, then the dose is given according to the schedule and is not "prn" or "as needed"." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.asNeeded[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="boolean" /> </type> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="MedicationAsNeededReason" /> </extension> <strength value="example" /> <description value="A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc." /> <valueSet value="http://hl7.org/fhir/ValueSet/medication-as-needed-reason" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="TQ1-9" /> </mapping> <mapping> <identity value="rim" /> <map value=".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code="as needed"].value=boolean or codable concept" /> </mapping> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept"> <path value="Dosage.asNeeded[x]" /> <sliceName value="asNeededCodeableConcept" /> <short value="Condition" /> <definition value="Condition for administration of medication can be: *a measured physiological value (plasma glucose level, body temperature, blood pressure); *a symptom or other condition (headache, itching). Relevant “as needed” conditions from NHG Table 25 form the value list for transmitting this concept in coded form. The conditions supported in the G-standard are included in file 362. The textual description of that code must always be provided as well. Physiological measurements or other conditions that are not included in the “as needed” conditions of NHG Table 25 can be expressed in free text using the OTH code." /> <comment value="If only one 'asNeeded' concept is exchanged within a Dosage, use Dosage.asNeeded[x]. Otherwise use the extension Dosage.extension:asNeeded.value[x] for when multiple 'asNeeded' concepts are to be exchanged. Can express "as needed" without a reason by setting the Boolean = True. In this case the CodeableConcept is not populated. Or you can express "as needed" with a reason by including the CodeableConcept. In this case the Boolean is assumed to be True. If you set the Boolean to False, then the dose is given according to the schedule and is not "prn" or "as needed"." /> <alias value="Criterium" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.asNeeded[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="MedicationAsNeededReason" /> </extension> <strength value="required" /> <description value="A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc." /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="TQ1-9" /> </mapping> <mapping> <identity value="rim" /> <map value=".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code="as needed"].value=boolean or codable concept" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19945" /> <comment value="Condition [DEPRECATED]" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-321" /> <comment value="Condition" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-72" /> <comment value="Condition" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-389" /> <comment value="Condition" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-676" /> <comment value="Condition" /> </mapping> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept.id"> <path value="Dosage.asNeeded[x].id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept.extension"> <path value="Dosage.asNeeded[x].extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept.coding"> <path value="Dosage.asNeeded[x].coding" /> <short value="Code defined by a terminology system" /> <definition value="A reference to a code defined by a terminology system." /> <comment value="Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true." /> <requirements value="Allows for alternative encodings within a code system, and translations to other code systems." /> <min value="0" /> <max value="*" /> <base> <path value="CodeableConcept.coding" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Coding" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE subset one of the sets of component 1-3 or 4-6" /> </mapping> <mapping> <identity value="rim" /> <map value="CV" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:Coding rdfs:subClassOf dt:CDCoding" /> </mapping> <mapping> <identity value="v2" /> <map value="C*E.1-8, C*E.10-22" /> </mapping> <mapping> <identity value="rim" /> <map value="union(., ./translation)" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding" /> </mapping> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept.text"> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable"> <valueBoolean value="true" /> </extension> <path value="Dosage.asNeeded[x].text" /> <short value="Plain text representation of the concept" /> <definition value="A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user." /> <comment value="Very often the text is the same as a displayName of one of the codings." /> <requirements value="The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source." /> <min value="0" /> <max value="1" /> <base> <path value="CodeableConcept.text" /> <min value="0" /> <max value="1" /> </base> <type> <code value="string" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="C*E.9. But note many systems use C*E.2 for this" /> </mapping> <mapping> <identity value="rim" /> <map value="./originalText[mediaType/code="text/plain"]/data" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-272" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-272" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-677" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-677" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-582" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-582" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-514" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-514" /> <comment value="Description" /> </mapping> </element> <element id="Dosage.site"> <path value="Dosage.site" /> <short value="Body site to administer to" /> <definition value="Body site to administer to." /> <comment value="If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension [bodySite](extension-bodysite.html). May be a summary code, or a reference to a very precise definition of the location, or both." /> <requirements value="A coded specification of the anatomic site where the medication first enters the body." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.site" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="MedicationAdministrationSite" /> </extension> <strength value="example" /> <description value="A coded concept describing the site location the medicine enters into or onto the body." /> <valueSet value="http://hl7.org/fhir/ValueSet/approach-site-codes" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> <mapping> <identity value="v2" /> <map value="RXR-2" /> </mapping> <mapping> <identity value="rim" /> <map value=".approachSiteCode" /> </mapping> </element> <element id="Dosage.route"> <path value="Dosage.route" /> <short value="RouteOfAdministration" /> <definition value="The route through which the medication is administered (oral, nasal, intravenous, etc.). The routes of administration supported in the G-standard are included in file 902, thesaurus number 7." /> <comment value="Please note that in contrast to the zib, this RouteOfAdministration concept is grouped under the DosingInstructions concept. This `.route` element shall have the same value when there are multiple DosingInstructions." /> <requirements value="A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body." /> <alias value="Toedieningsweg" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.route" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="RouteOfAdministration" /> </extension> <strength value="required" /> <description value="A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject." /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.1--20200901000000" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> <mapping> <identity value="v2" /> <map value="RXR-1" /> </mapping> <mapping> <identity value="rim" /> <map value=".routeCode" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19941" /> <comment value="RouteOfAdministration [DEPRECATED]" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-303" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-430" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-54" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-371" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-648" /> <comment value="RouteOfAdministration" /> </mapping> </element> <element id="Dosage.method"> <path value="Dosage.method" /> <short value="Technique for administering medication" /> <definition value="Technique for administering medication." /> <comment value="Terminologies used often pre-coordinate this term with the route and or form of administration." /> <requirements value="A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections. For examples, Slow Push; Deep IV." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.method" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="MedicationAdministrationMethod" /> </extension> <strength value="example" /> <description value="A coded concept describing the technique by which the medicine is administered." /> <valueSet value="http://hl7.org/fhir/ValueSet/administration-method-codes" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> <mapping> <identity value="v2" /> <map value="RXR-4" /> </mapping> <mapping> <identity value="rim" /> <map value=".doseQuantity" /> </mapping> </element> <element id="Dosage.doseAndRate"> <path value="Dosage.doseAndRate" /> <short value="Amount of medication administered" /> <definition value="The amount of medication administered." /> <min value="0" /> <max value="*" /> <base> <path value="Dosage.doseAndRate" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Element" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="TQ1-2" /> </mapping> </element> <element id="Dosage.doseAndRate.id"> <path value="Dosage.doseAndRate.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.doseAndRate.extension"> <path value="Dosage.doseAndRate.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.doseAndRate.type"> <path value="Dosage.doseAndRate.type" /> <short value="The kind of dose or rate specified" /> <definition value="The kind of dose or rate specified, for example, ordered or calculated." /> <comment value="Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination." /> <requirements value="If the type is not populated, assume to be "ordered"." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.type" /> <min value="0" /> <max value="1" /> </base> <type> <code value="CodeableConcept" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <binding> <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName"> <valueString value="DoseAndRateType" /> </extension> <strength value="example" /> <description value="The kind of dose or rate specified." /> <valueSet value="http://hl7.org/fhir/ValueSet/dose-rate-type" /> </binding> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="CE/CNE/CWE" /> </mapping> <mapping> <identity value="rim" /> <map value="CD" /> </mapping> <mapping> <identity value="orim" /> <map value="fhir:CodeableConcept rdfs:subClassOf dt:CD" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-21; RXE-23" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]"> <path value="Dosage.doseAndRate.dose[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> <short value="Dose" /> <definition value="The dose indicates the amount/unit per administration. The unit can be any unit that can occur with this particular medicine. For liquids and other divisible products, a volume measure (preferably "ml") will usually be used. In many cases, the prescriber may want to specify the dosage in units of weight of the active substance. If only the substance is indicated and not the product, then the amount of that substance is specified. For example, Paracetamol 1000 mg is equivalent to Paracetamol 500 mg tablets, 2 tablets (or units). The dosage is sometimes indicated in a calculation, which often uses the patient's body weight or body surface area as a parameter. However, the calculation remains nothing more than a tool to aid decision-making. In continuous administration, alongside the administration speed, the dose can be specified (e.g., 20 ml in a syringe or 500 ml in a bag), but it is often omitted. Even a general dosing recommendation such as 'Use according to protocol' or 'See instructions for use' can be adequate. Then, no dose is specified." /> <comment value="Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours." /> <requirements value="The amount of therapeutic or other substance given at one administration event." /> <alias value="Keerdosis" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.dose[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Range" /> </type> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-2, RXE-3" /> </mapping> <mapping> <identity value="rim" /> <map value=".doseQuantity" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19940" /> <comment value="Dose [DEPRECATED]" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-316" /> <comment value="Dose" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-67" /> <comment value="Dose" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-384" /> <comment value="Dose" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-655" /> <comment value="Dose" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange"> <path value="Dosage.doseAndRate.dose[x]" /> <sliceName value="doseRange" /> <short value="Amount of medication per dose" /> <definition value="Amount of medication per dose." /> <comment value="Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours." /> <requirements value="The amount of therapeutic or other substance given at one administration event." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.dose[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Range" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-2, RXE-3" /> </mapping> <mapping> <identity value="rim" /> <map value=".doseQuantity" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange.id"> <path value="Dosage.doseAndRate.dose[x].id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange.extension"> <path value="Dosage.doseAndRate.dose[x].extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange.low"> <path value="Dosage.doseAndRate.dose[x].low" /> <short value="minimumValue" /> <definition value="The minimal value of the range. The boundary is inclusive." /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <alias value="minimumWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Range.low" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="v2" /> <map value="NR.1" /> </mapping> <mapping> <identity value="rim" /> <map value="./low" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange.high"> <path value="Dosage.doseAndRate.dose[x].high" /> <short value="maximumValue" /> <definition value="The maximum value of the range. The boundary is inclusive." /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <alias value="maximumWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Range.high" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="v2" /> <map value="NR.2" /> </mapping> <mapping> <identity value="rim" /> <map value="./high" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseQuantity"> <path value="Dosage.doseAndRate.dose[x]" /> <sliceName value="doseQuantity" /> <short value="nominalValue" /> <definition value="Amount of medication per dose. The nominal value of the quantity." /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <requirements value="The amount of therapeutic or other substance given at one administration event." /> <alias value="nominaleWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.dose[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-2, RXE-3" /> </mapping> <mapping> <identity value="rim" /> <map value=".doseQuantity" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]"> <path value="Dosage.doseAndRate.rate[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> <short value="AdministeringSpeed" /> <definition value="The administering speed is used in slow administration of liquid. In practice, the measuring unit is almost always ml/hour, but can also be parametric with i.e. body weight or body surface area (in the case of a MedicationAgreement, VariableDosingRegimen or AdministrationAgreement). Entering an interval (such as 0-10 ml/hour) is also a commonly used option. For example, with an administering speed of 10ml/hour: * value = 10 * unit = ml/hour" /> <comment value="It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate. It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour." /> <requirements value="Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period." /> <alias value="Toedieningssnelheid" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.rate[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Ratio" /> </type> <type> <code value="Range" /> </type> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXE22, RXE23, RXE-24" /> </mapping> <mapping> <identity value="rim" /> <map value=".rateQuantity" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19942" /> <comment value="AdministeringSpeed" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange"> <path value="Dosage.doseAndRate.rate[x]" /> <sliceName value="rateRange" /> <short value="Amount of medication per unit of time" /> <definition value="Amount of medication per unit of time." /> <comment value="It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate. It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour." /> <requirements value="Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.rate[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Range" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXE22, RXE23, RXE-24" /> </mapping> <mapping> <identity value="rim" /> <map value=".rateQuantity" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange.id"> <path value="Dosage.doseAndRate.rate[x].id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange.extension"> <path value="Dosage.doseAndRate.rate[x].extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange.low"> <path value="Dosage.doseAndRate.rate[x].low" /> <short value="minimumValue" /> <definition value="The minimal value of the range. The boundary is inclusive." /> <comment value="If the low element is missing, the low boundary is not known." /> <alias value="minimumWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Range.low" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="v2" /> <map value="NR.1" /> </mapping> <mapping> <identity value="rim" /> <map value="./low" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange.high"> <path value="Dosage.doseAndRate.rate[x].high" /> <short value="maximumValue" /> <definition value="The maximum value of the range. The boundary is inclusive." /> <comment value="If the high element is missing, the high boundary is not known." /> <alias value="maximumWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Range.high" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="v2" /> <map value="NR.2" /> </mapping> <mapping> <identity value="rim" /> <map value="./high" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateQuantity"> <path value="Dosage.doseAndRate.rate[x]" /> <sliceName value="rateQuantity" /> <short value="nominalValue" /> <definition value="The nominal value of the quantity." /> <comment value="It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate. It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour." /> <requirements value="Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period." /> <alias value="nominaleWaarde" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.doseAndRate.rate[x]" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="RXE22, RXE23, RXE-24" /> </mapping> <mapping> <identity value="rim" /> <map value=".rateQuantity" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod"> <path value="Dosage.maxDosePerPeriod" /> <short value="MaximumDose" /> <definition value="A maximum dose maximizes (in time) the usage of a drug in an 'as needed' prescription." /> <comment value="This is intended for use as an adjunct to the dosage when there is an upper cap. For example "2 tablets every 4 hours to a maximum of 8/day"." /> <requirements value="The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time. For example, 1000mg in 24 hours." /> <alias value="MaximaleDosering" /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.maxDosePerPeriod" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Ratio" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="rat-1" /> <severity value="error" /> <human value="Numerator and denominator SHALL both be present, or both are absent. If both are absent, there SHALL be some extension present" /> <expression value="(numerator.empty() xor denominator.exists()) and (numerator.exists() or extension.exists())" /> <xpath value="(count(f:numerator) = count(f:denominator)) and ((count(f:numerator) > 0) or (count(f:extension) > 0))" /> <source value="http://hl7.org/fhir/StructureDefinition/Ratio" /> </constraint> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="N/A" /> </mapping> <mapping> <identity value="rim" /> <map value="RTO" /> </mapping> <mapping> <identity value="v2" /> <map value="RXO-23, RXE-19" /> </mapping> <mapping> <identity value="rim" /> <map value=".maxDoseQuantity" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19946" /> <comment value="MaximumDose" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod.id"> <path value="Dosage.maxDosePerPeriod.id" /> <representation value="xmlAttr" /> <short value="Unique id for inter-element referencing" /> <definition value="Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." /> <min value="0" /> <max value="1" /> <base> <path value="Element.id" /> <min value="0" /> <max value="1" /> </base> <type> <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type"> <valueUrl value="string" /> </extension> <code value="http://hl7.org/fhirpath/System.String" /> </type> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod.extension"> <path value="Dosage.maxDosePerPeriod.extension" /> <slicing> <discriminator> <type value="value" /> <path value="url" /> </discriminator> <description value="Extensions are always sliced by (at least) url" /> <rules value="open" /> </slicing> <short value="Additional content defined by implementations" /> <definition value="May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." /> <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." /> <alias value="extensions" /> <alias value="user content" /> <min value="0" /> <max value="*" /> <base> <path value="Element.extension" /> <min value="0" /> <max value="*" /> </base> <type> <code value="Extension" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="ext-1" /> <severity value="error" /> <human value="Must have either extensions or value[x], not both" /> <expression value="extension.exists() != value.exists()" /> <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" /> <source value="http://hl7.org/fhir/StructureDefinition/Extension" /> </constraint> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="rim" /> <map value="N/A" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod.numerator"> <path value="Dosage.maxDosePerPeriod.numerator" /> <short value="A fixed quantity (no comparator)" /> <definition value="The comparator is not used on a SimpleQuantity" /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <min value="0" /> <max value="1" /> <base> <path value="Ratio.numerator" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="rim" /> <map value=".numerator" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod.denominator"> <path value="Dosage.maxDosePerPeriod.denominator" /> <short value="A fixed quantity (no comparator)" /> <definition value="The comparator is not used on a SimpleQuantity" /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <min value="0" /> <max value="1" /> <base> <path value="Ratio.denominator" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="rim" /> <map value=".denominator" /> </mapping> </element> <element id="Dosage.maxDosePerAdministration"> <path value="Dosage.maxDosePerAdministration" /> <short value="Upper limit on medication per administration" /> <definition value="Upper limit on medication per administration." /> <comment value="This is intended for use as an adjunct to the dosage when there is an upper cap. For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg." /> <requirements value="The maximum total quantity of a therapeutic substance that may be administered to a subject per administration." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.maxDosePerAdministration" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="rim" /> <map value="not supported" /> </mapping> </element> <element id="Dosage.maxDosePerLifetime"> <path value="Dosage.maxDosePerLifetime" /> <short value="Upper limit on medication per lifetime of the patient" /> <definition value="Upper limit on medication per lifetime of the patient." /> <comment value="The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator." /> <requirements value="The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject." /> <min value="0" /> <max value="1" /> <base> <path value="Dosage.maxDosePerLifetime" /> <min value="0" /> <max value="1" /> </base> <type> <code value="Quantity" /> <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </type> <condition value="ele-1" /> <constraint> <key value="ele-1" /> <severity value="error" /> <human value="All FHIR elements must have a @value or children" /> <expression value="hasValue() or (children().count() > id.count())" /> <xpath value="@value|f:*|h:div" /> <source value="http://hl7.org/fhir/StructureDefinition/Element" /> </constraint> <constraint> <key value="qty-3" /> <severity value="error" /> <human value="If a code for the unit is present, the system SHALL also be present" /> <expression value="code.empty() or system.exists()" /> <xpath value="not(exists(f:code)) or exists(f:system)" /> <source value="http://hl7.org/fhir/StructureDefinition/Quantity" /> </constraint> <constraint> <key value="sqty-1" /> <severity value="error" /> <human value="The comparator is not used on a SimpleQuantity" /> <expression value="comparator.empty()" /> <xpath value="not(exists(f:comparator))" /> <source value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity" /> </constraint> <isModifier value="false" /> <isSummary value="true" /> <mapping> <identity value="rim" /> <map value="n/a" /> </mapping> <mapping> <identity value="v2" /> <map value="SN (see also Range) or CQ" /> </mapping> <mapping> <identity value="rim" /> <map value="PQ, IVL<PQ>, MO, CO, depending on the values" /> </mapping> <mapping> <identity value="rim" /> <map value="not supported" /> </mapping> </element> </snapshot> <differential> <element id="Dosage"> <path value="Dosage" /> <short value="DosingInstructions" /> <definition value="Indicates how the medication is/was taken or should be taken by the patient. Instructions for the administrator to administer the medication (the patient themselves, a nurse or other aid). When taking stock of medication use, the dosage describes the pattern of use established by the patient." /> <comment value="This element _mostly_ represents the DosingInstructions container from zib InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are **duplicated** in every repetition of this element, even though these concepts should be present just once according to the zib. This element does not contain a mapping to the Dosage container from zib InstructionsForUse. However, all child concepts of the Dosage concept are mapped. If an instance of zib container DosingInstructions contains multiple Dosage containers, each of these results in a separate instance of the FHIR Dosage data type conforming to this profile, wherein `.sequence` (zib concept SequenceNumber) and `.timing.repeat.bounds[x]:boundsDuration` (zib concept DoseDuration) are equal." /> <alias value="Doseerinstructie" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.22095" /> <comment value="DosingInstructions" /> </mapping> </element> <element id="Dosage.extension:asNeeded"> <path value="Dosage.extension" /> <sliceName value="asNeeded" /> <type> <code value="Extension" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/ext-Dosage-AsNeededFor" /> </type> </element> <element id="Dosage.extension:asNeeded.value[x]"> <path value="Dosage.extension.value[x]" /> <short value="Condition" /> <definition value="The condition for administering medication can be: * a physiological measurement value (plasma glucose concentration, body temperature, blood pressure); * a symptom or other circumstance (in the event of a headache, or itch). Supplemental information from G-standard bst362 make up the list of values for coded entering of this concept. Also always include the textual description of that code. Physiological measurement values or other conditions that do not occur in bst362 do not need to be coded. These can be expressed in free text in the Description concept." /> <alias value="Criterium" /> <binding> <strength value="required" /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000" /> </binding> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19945" /> <comment value="Condition" /> </mapping> </element> <element id="Dosage.sequence"> <path value="Dosage.sequence" /> <short value="SequenceNumber" /> <definition value="This indicates the sequence of the dosing instructions within the medication agreement." /> <alias value="Volgnummer" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.22503" /> <comment value="SequenceNumber" /> </mapping> </element> <element id="Dosage.additionalInstruction"> <path value="Dosage.additionalInstruction" /> <short value="AdditionalInstructions" /> <definition value="The additional instructions contain extra information on the use of the current prescription. The additional instructions applies to the entire instructions for use and not to an individual dosage. This includes all instructions for use. The text can come from the original “paper" medication prescription, but can also be generated from the coded information. The instructions may not conflict with other components of the medication agreement/ administration agreement. The instructions can also refer to an existing protocol. In the case of an external dosing regimen (e.g., "according to thrombosis service regimen"), OTH is used. The texts in the G-standard that can support this attribute are included in table 362 where the texts from the general practitioner' standard 'NHG-Tabel 25-component b: 'aanvullende teksten’ ' are included. These texts can only be used when it is not possible to include this information in the other structured elements of the Instructions for Use. A free-text explanation of the Instructions for Use can be placed under code OTH if it is not possible to record it in a structured manner within the Instructions for Use." /> <comment value="Please note that in contrast to the zib, this AdditionalInstructions concept is grouped under the DosingInstructions concept. This `.additionalInstruction` element shall have the same value when there are multiple DosingInstructions." /> <alias value="AanvullendeInstructie" /> <binding> <strength value="required" /> <description value="WCIAv3 Tabel 25 B-codes subset voor aanvullende gebruiksinstructies" /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.20.77.11.9--20160407000000" /> </binding> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-51" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-51" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-649" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-649" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-300" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-300" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-368" /> <comment value="AdditionalInstructions" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-368" /> <comment value="AdditionalInstructions" /> </mapping> </element> <element id="Dosage.timing"> <path value="Dosage.timing" /> <short value="AdministeringSchedule" /> <definition value="Specifications of the times at which the medication is to be administered. This is indicated as follows: * Time(s) (16:00) or indications (“before meals”) at which the medication is to be taken each day. * A specific number of times the medication is to be taken each day ("3x a day"), indicated with the frequency. * A time interval between consecutive doses (“Every 2 hours”, “every 3 days”), indicated with the word Interval. * Combined periods with an interval and duration (“1 daily for three out of four weeks: the pill schedule”) If a certain medication is not to be taken daily, the aforementioned can be combined with daily indications: * One or more week days on which the medication is to be administered (e.g. “Monday, Wednesday, Friday”) * ”3x a week”, “2x a month”. The specified administration “infinite” is automatically to be repeated until: * The end date and time has been reached * The total administration duration has been reached (14 days) * A specific amount of administrations has been reached (“20 doses”), to be entered in the Frequency concept." /> <alias value="Toedieningsschema" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19948" /> <comment value="AdministeringSchedule" /> </mapping> </element> <element id="Dosage.timing.repeat.extension:timingExact"> <path value="Dosage.timing.repeat.extension" /> <sliceName value="timingExact" /> <type> <code value="Extension" /> <profile value="http://hl7.org/fhir/StructureDefinition/timing-exact" /> </type> </element> <element id="Dosage.timing.repeat.extension:timingExact.value[x]"> <path value="Dosage.timing.repeat.extension.value[x]" /> <definition value="Indicates that the timing as specified by `.frequency`, `.period` and `.periodUnit` should be strictly interpreted. This is the case when the zib concept Interval is expressed using these elements (as opposed to the zib concept Frequency). The times can be chosen freely, but distribution throughout the day is more precise, and the interval between times is important (e.g. in the case of antibiotics). In the case of Baxter packs and intramural care, such a prescription is used to draw up a (location-specific) outline for distribution times (logistics)." /> <comment value="Notes on the zib concepts Frequency and Interval: 1. An interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period` and `.periodUnit`. However, the zib differentiates between the two concepts in the timing precision (the Interval concept defines precise intervals while the Frequency concept defines approximate intervals). When the interval is precise, this is communicated using the extension in `.extension:timingExact`. 2. On the other hand, the zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element. 3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated. In summary: * zib concept Frequency: * With time unit: * Nominal value: `.frequency`, `.period` and `.periodUnit` * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit` * Without time unit: * Nominal value: `.count` * Range: `.count` and `.countMax` * zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit` and `.extension:timingExact` (set to _true_)" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval (implicit, main mapping is on `.frequency`, `.period` and `.periodMax`)" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-271" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-271" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-672" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-672" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-580" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-580" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-412" /> <comment value="(negative of) IsFlexible" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-412" /> <comment value="(negative of) IsFlexible" /> </mapping> </element> <element id="Dosage.timing.repeat.bounds[x]"> <path value="Dosage.timing.repeat.bounds[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> </element> <element id="Dosage.timing.repeat.bounds[x]:boundsDuration"> <path value="Dosage.timing.repeat.bounds[x]" /> <sliceName value="boundsDuration" /> <short value="DoseDuration" /> <definition value="The intended time duration for these dosing instructions, e.g. 5 days or 8 weeks. In the case of medication for an indefinite period, the dosing duration is left empty in the last dosing instruction." /> <alias value="Doseerduur" /> <type> <code value="Duration" /> </type> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.22506" /> <comment value="DoseDuration" /> </mapping> </element> <element id="Dosage.timing.repeat.count"> <path value="Dosage.timing.repeat.count" /> <short value="Frequency / minimumValue / nominalValue" /> <definition value="Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by this `.count` element and optionally `.countMax` if a range should be represented." /> <comment value="Notes on the zib concept Frequency can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="nominaleWaarde" /> <alias value="minimumWaarde" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency (single use only)" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> </element> <element id="Dosage.timing.repeat.countMax"> <path value="Dosage.timing.repeat.countMax" /> <short value="Frequency / maximumValue" /> <definition value="Usually, frequency comprises both amount and time unit (3 times a day), but it can occur without the time unit (single use). This is represented by the `.count` element and optionally `.countMax` if a range should be represented." /> <comment value="Notes on the zib concept Frequency can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="maximumWaarde" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.timing.repeat.duration"> <path value="Dosage.timing.repeat.duration" /> <short value="DurationOfAdministration" /> <definition value="The duration of administration defines the length of time during which the drug is administered and is mainly used in the slow parenteral administration of fluids. The `durationUnit` defines the time unit." /> <alias value="Toedieningsduur" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.23141" /> <comment value="DurationOfAdministration" /> </mapping> </element> <element id="Dosage.timing.repeat.durationUnit"> <path value="Dosage.timing.repeat.durationUnit" /> <short value="DurationOfAdministration" /> <definition value="The units of time, in UCUM units, for the duration of administration of time during which the drug is administered." /> <alias value="Toedieningsduur" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.23141" /> <comment value="DurationOfAdministration" /> </mapping> </element> <element id="Dosage.timing.repeat.frequency"> <path value="Dosage.timing.repeat.frequency" /> <short value="Frequency / minimumValue / nominalValue / Interval" /> <definition value="The `.frequency` element indicates either the number of dose moments per time unit (zib concept Frequency) or the time between dose times (zib concept Interval). If `.frequencyMax` is present, this `.frequency` element indicates the lower bound of the allowed range of the frequency." /> <comment value="Notes on the zib concepts Frequency and Interval, The zib differentiates between the two concepts in the specific usage of the extension `.extension:timingExact` and the element `.timeOfDay` combined: 1. The zib Interval (in FHIR) is just a normal frequency of 1 (combined with a period based on the interval length) and is represented in FHIR as just another frequency using `.frequency` (set to 1), `.period`, `.periodUnit`, the extension `.extension:timingExact` set to _true_ and the absence of the element `.timeOfDay`. 2. The zib Frequency concept might be used to express a single-use, non-repeating series by omitting the time unit. In FHIR, this is _not_ represented as a frequency, but with the `.count` element. 3. Lastly, the Frequency concept may be used to express either a single nominal value or a range. The extension `.extension:timingExact` can be used to specify the precision of the timing of the administration (i.e. the element `.timeOfDay`). When this element is meant to convey the zib Frequency concept this can be, unlike the zib concept Interval, either _true_or _false_. A range is represented by respectively setting the minimum and maximum value to `.frequency` and `.frequencyMax`, or to `.count` and `.countMax` for single-use events as mentioned in the second point. A nominal value is expressed by setting its value to `.frequency` or to `.count` for single-use events, and leaving `.frequencyMax` and `.countMax` unpopulated. In summary: * zib concept Frequency: * With time unit (precision of the timing can be further specified with the extension `.extension:timingExact`): * Nominal value: `.frequency`, `.period` and `.periodUnit` * Range: `.frequency`, `.frequencyMax`, `.period` and `.periodUnit` * Without time unit: * Nominal value: `.count` * Range: `.count` and `.countMax` * zib concept Interval: `.frequency` (set to 1), `.period`, `.periodUnit`, `.extension:timingExact` (SHALL be set to _true_) and the absence of `.timeOfDay`." /> <alias value="Frequentie" /> <alias value="minimumWaarde" /> <alias value="nominaleWaarde" /> <alias value="Interval" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval" /> </mapping> </element> <element id="Dosage.timing.repeat.frequencyMax"> <path value="Dosage.timing.repeat.frequencyMax" /> <short value="Frequency / maximumValue" /> <comment value="Notes on the zib concept Frequency can be found in the comment of the `.frequency` element." /> <alias value="maximumWaarde" /> <alias value="Frequentie" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.timing.repeat.period"> <path value="Dosage.timing.repeat.period" /> <short value="Frequency / Interval" /> <definition value="Indicates the duration of time over which repetitions are to occur; e.g. to express "3 times per day", 3 would be the frequency and "1 day" would be the period. If `.periodMax` is present, this element indicates the lower bound of the allowed range of the period length." /> <comment value="Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="Interval" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency" /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval" /> </mapping> </element> <element id="Dosage.timing.repeat.periodUnit"> <path value="Dosage.timing.repeat.periodUnit" /> <short value="Frequency / Interval" /> <definition value="The units of time for the period in UCUM units for Frequency and Interval." /> <comment value="Notes on the zib concepts Frequency and Interval can be found in the comment of the `.frequency` element." /> <alias value="Frequentie" /> <alias value="Interval" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19949" /> <comment value="Frequency. When frequency is used, set `.extension.timingExact` to false." /> </mapping> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19950" /> <comment value="Interval" /> </mapping> </element> <element id="Dosage.timing.repeat.dayOfWeek"> <path value="Dosage.timing.repeat.dayOfWeek" /> <short value="WeekDay" /> <definition value="WeekDay indicates a pattern of doses on fixed week days." /> <comment value="If no days are specified, the action is assumed to happen every day as otherwise specified." /> <alias value="Weekdag" /> <binding> <strength value="required" /> <description value="Use ConceptMap 'WeekdagCodelijst_to_DaysOfWeek' to translate zib terminology to profile terminology in ValueSet 'DaysOfWeek'" /> <valueSet value="http://hl7.org/fhir/ValueSet/days-of-week|4.0.1"> <extension url="http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap"> <valueCanonical value="http://nictiz.nl/fhir/ConceptMap/WeekdagCodelijst-to-DaysOfWeek" /> </extension> </valueSet> </binding> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19952" /> <comment value="WeekDay" /> </mapping> </element> <element id="Dosage.timing.repeat.timeOfDay"> <path value="Dosage.timing.repeat.timeOfDay" /> <short value="AdministrationTime" /> <definition value="The time of administration is a specific time of day (on the clock). This time usually isn’t (intended to be) exact. There can be multiple administering times in one day. The ideal time of administration can also be entered as a time of day (morning, afternoon, evening, night-time). The administration time is then to be left empty, and the time of day can be entered in the TimeOfDay concept." /> <comment value="If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa." /> <alias value="Toedientijd" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19951" /> <comment value="AdministrationTime" /> </mapping> </element> <element id="Dosage.timing.repeat.when"> <path value="Dosage.timing.repeat.when" /> <short value="TimeOfDay" /> <definition value="Time of day: morning, afternoon, evening, night." /> <comment value="If there's a `.timeOfDay`, there cannot be a `.when`, or vice versa." /> <alias value="Dagdeel" /> <binding> <strength value="required" /> <description value="Use ConceptMap 'DagdeelCodelijst_to_EventTiming' to translate zib terminology to profile terminology in ValueSet 'EventTiming'" /> <valueSet value="http://hl7.org/fhir/ValueSet/event-timing"> <extension url="http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap"> <valueCanonical value="http://nictiz.nl/fhir/ConceptMap/DagdeelCodelijst-to-EventTiming" /> </extension> </valueSet> </binding> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19953" /> <comment value="TimeOfDay" /> </mapping> </element> <element id="Dosage.asNeeded[x]"> <path value="Dosage.asNeeded[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept"> <path value="Dosage.asNeeded[x]" /> <sliceName value="asNeededCodeableConcept" /> <short value="Condition" /> <definition value="Condition for administration of medication can be: *a measured physiological value (plasma glucose level, body temperature, blood pressure); *a symptom or other condition (headache, itching). Relevant “as needed” conditions from NHG Table 25 form the value list for transmitting this concept in coded form. The conditions supported in the G-standard are included in file 362. The textual description of that code must always be provided as well. Physiological measurements or other conditions that are not included in the “as needed” conditions of NHG Table 25 can be expressed in free text using the OTH code." /> <comment value="If only one 'asNeeded' concept is exchanged within a Dosage, use Dosage.asNeeded[x]. Otherwise use the extension Dosage.extension:asNeeded.value[x] for when multiple 'asNeeded' concepts are to be exchanged. Can express "as needed" without a reason by setting the Boolean = True. In this case the CodeableConcept is not populated. Or you can express "as needed" with a reason by including the CodeableConcept. In this case the Boolean is assumed to be True. If you set the Boolean to False, then the dose is given according to the schedule and is not "prn" or "as needed"." /> <alias value="Criterium" /> <type> <code value="CodeableConcept" /> </type> <binding> <strength value="required" /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.4--20200901000000" /> </binding> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19945" /> <comment value="Condition [DEPRECATED]" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-321" /> <comment value="Condition" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-72" /> <comment value="Condition" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-389" /> <comment value="Condition" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-676" /> <comment value="Condition" /> </mapping> </element> <element id="Dosage.asNeeded[x]:asNeededCodeableConcept.text"> <path value="Dosage.asNeeded[x].text" /> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-272" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-272" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-677" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-677" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-582" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-582" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc1-20250522" /> <map value="mp-dataelement9x-514" /> <comment value="Description" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-514" /> <comment value="Description" /> </mapping> </element> <element id="Dosage.route"> <path value="Dosage.route" /> <short value="RouteOfAdministration" /> <definition value="The route through which the medication is administered (oral, nasal, intravenous, etc.). The routes of administration supported in the G-standard are included in file 902, thesaurus number 7." /> <comment value="Please note that in contrast to the zib, this RouteOfAdministration concept is grouped under the DosingInstructions concept. This `.route` element shall have the same value when there are multiple DosingInstructions." /> <alias value="Toedieningsweg" /> <binding> <strength value="required" /> <valueSet value="http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.12.1--20200901000000" /> </binding> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19941" /> <comment value="RouteOfAdministration [DEPRECATED]" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-303" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-430" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-54" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-371" /> <comment value="RouteOfAdministration" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-648" /> <comment value="RouteOfAdministration" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]"> <path value="Dosage.doseAndRate.dose[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> <short value="Dose" /> <definition value="The dose indicates the amount/unit per administration. The unit can be any unit that can occur with this particular medicine. For liquids and other divisible products, a volume measure (preferably "ml") will usually be used. In many cases, the prescriber may want to specify the dosage in units of weight of the active substance. If only the substance is indicated and not the product, then the amount of that substance is specified. For example, Paracetamol 1000 mg is equivalent to Paracetamol 500 mg tablets, 2 tablets (or units). The dosage is sometimes indicated in a calculation, which often uses the patient's body weight or body surface area as a parameter. However, the calculation remains nothing more than a tool to aid decision-making. In continuous administration, alongside the administration speed, the dose can be specified (e.g., 20 ml in a syringe or 500 ml in a bag), but it is often omitted. Even a general dosing recommendation such as 'Use according to protocol' or 'See instructions for use' can be adequate. Then, no dose is specified." /> <alias value="Keerdosis" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19940" /> <comment value="Dose [DEPRECATED]" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-316" /> <comment value="Dose" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-67" /> <comment value="Dose" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-384" /> <comment value="Dose" /> </mapping> <mapping> <identity value="mp-dataset-mp9-300-rc2-20260213" /> <map value="mp-dataelement9x-655" /> <comment value="Dose" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange"> <path value="Dosage.doseAndRate.dose[x]" /> <sliceName value="doseRange" /> <type> <code value="Range" /> </type> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange.low"> <path value="Dosage.doseAndRate.dose[x].low" /> <short value="minimumValue" /> <definition value="The minimal value of the range. The boundary is inclusive." /> <alias value="minimumWaarde" /> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseRange.high"> <path value="Dosage.doseAndRate.dose[x].high" /> <short value="maximumValue" /> <definition value="The maximum value of the range. The boundary is inclusive." /> <alias value="maximumWaarde" /> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.dose[x]:doseQuantity"> <path value="Dosage.doseAndRate.dose[x]" /> <sliceName value="doseQuantity" /> <short value="nominalValue" /> <definition value="Amount of medication per dose. The nominal value of the quantity." /> <alias value="nominaleWaarde" /> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]"> <path value="Dosage.doseAndRate.rate[x]" /> <slicing> <discriminator> <type value="type" /> <path value="$this" /> </discriminator> <rules value="open" /> </slicing> <short value="AdministeringSpeed" /> <definition value="The administering speed is used in slow administration of liquid. In practice, the measuring unit is almost always ml/hour, but can also be parametric with i.e. body weight or body surface area (in the case of a MedicationAgreement, VariableDosingRegimen or AdministrationAgreement). Entering an interval (such as 0-10 ml/hour) is also a commonly used option. For example, with an administering speed of 10ml/hour: * value = 10 * unit = ml/hour" /> <alias value="Toedieningssnelheid" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19942" /> <comment value="AdministeringSpeed" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange"> <path value="Dosage.doseAndRate.rate[x]" /> <sliceName value="rateRange" /> <type> <code value="Range" /> </type> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange.low"> <path value="Dosage.doseAndRate.rate[x].low" /> <short value="minimumValue" /> <definition value="The minimal value of the range. The boundary is inclusive." /> <alias value="minimumWaarde" /> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.2" /> <comment value="minimumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateRange.high"> <path value="Dosage.doseAndRate.rate[x].high" /> <short value="maximumValue" /> <definition value="The maximum value of the range. The boundary is inclusive." /> <alias value="maximumWaarde" /> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.3" /> <comment value="maximumValue" /> </mapping> </element> <element id="Dosage.doseAndRate.rate[x]:rateQuantity"> <path value="Dosage.doseAndRate.rate[x]" /> <sliceName value="rateQuantity" /> <short value="nominalValue" /> <definition value="The nominal value of the quantity." /> <alias value="nominaleWaarde" /> <type> <code value="Quantity" /> </type> <mapping> <identity value="zib-range-v1.0.1-2020EN" /> <map value="NL-CM:20.1.4" /> <comment value="nominalValue" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod"> <path value="Dosage.maxDosePerPeriod" /> <short value="MaximumDose" /> <definition value="A maximum dose maximizes (in time) the usage of a drug in an 'as needed' prescription." /> <alias value="MaximaleDosering" /> <mapping> <identity value="zib-instructionsforuse-v1.2.1-2020EN" /> <map value="NL-CM:9.12.19946" /> <comment value="MaximumDose" /> </mapping> </element> <element id="Dosage.maxDosePerPeriod.numerator"> <path value="Dosage.maxDosePerPeriod.numerator" /> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> </element> <element id="Dosage.maxDosePerPeriod.denominator"> <path value="Dosage.maxDosePerPeriod.denominator" /> <type> <code value="Quantity" /> <profile value="http://nictiz.nl/fhir/StructureDefinition/pattern-GstdSimpleQuantity" /> </type> </element> </differential> </StructureDefinition>