<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="medication-high-risk" />
  <meta>
    <lastUpdated value="2019-12-20T21:25:25.035+00:00" />
  </meta>
  <text>
    <status value="generated" />
    <div xmlns="http://www.w3.org/1999/xhtml">
      <table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;">
        <tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;">
          <th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/formats.html#table" title="The logical name of the element">Name</a>
          </th>
          <th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/formats.html#table" title="Information about the use of the element">Flags</a>
          </th>
          <th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/formats.html#table" title="Minimum and Maximum # of times the the element can appear in the instance">Card.</a>
          </th>
          <th style="width: 100px" class="hierarchy">
            <a href="http://hl7.org/fhir/formats.html#table" title="Reference to the type of the element">Type</a>
          </th>
          <th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/formats.html#table" title="Additional information about the element">Description &amp; Constraints</a>
            <span style="float: right">
              <a href="http://hl7.org/fhir/formats.html#table" title="Legend for this format">
                <img src="http://hl7.org/fhir/help16.png" alt="doco" style="background-color: inherit" />
              </a>
            </span>
          </th>
        </tr>
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;">
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy">
            <img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="icon_element.gif" alt="." style="background-color: white; background-color: inherit" title="Element" class="hierarchy" />
            <a href="{{[id]}}-definitions.html#Observation" title="Finding of whether the patient has a high-risk allele for a particular medication.">Observation</a>
            <a name="Observation"></a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <span style="opacity: 0.4">0</span>
            <span style="opacity: 0.5">..</span>
            <span style="opacity: 0.4">*</span>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Medication High Risk</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)" class="hierarchy">
            <img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy" />
            <a href="{{[id]}}-definitions.html#Observation.code" title="todo.">code</a>
            <a name="Observation.code"></a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Genomic variation's effect on high-risk allele<br /><span style="font-weight:bold">Required Pattern: </span><span style="color: darkgreen">At least the following</span></td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;">
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)" class="hierarchy">
            <img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="icon_fixed.gif" alt="." style="background-color: white; background-color: inherit" title="Fixed Value" class="hierarchy" />
            <a href="http://hl7.org/fhir/datatypes-definitions.html#CodeableConcept.coding">coding</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..*</td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/datatypes.html#Coding">Coding</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Code defined by a terminology system<br /><span style="font-weight: bold">Fixed Value: </span><span style="color: darkgreen">(complex)</span></td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy">
            <img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="icon_fixed.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Fixed Value" class="hierarchy" />
            <a href="http://hl7.org/fhir/datatypes-definitions.html#Coding.system">system</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/datatypes.html#uri">uri</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Identity of the terminology system<br /><span style="font-weight: bold">Fixed Value: </span><a style="color: darkgreen" href="http://hl7.org/fhir/loinc.html">http://loinc.org</a></td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;">
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)" class="hierarchy">
            <img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="icon_fixed.gif" alt="." style="background-color: white; background-color: inherit" title="Fixed Value" class="hierarchy" />
            <a href="http://hl7.org/fhir/datatypes-definitions.html#Coding.code">code</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/datatypes.html#code">code</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Symbol in syntax defined by the system<br /><span style="font-weight: bold">Fixed Value: </span><span style="color: darkgreen">83009-1</span></td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)" class="hierarchy">
            <img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy" />
            <img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy" />
            <a href="{{[id]}}-definitions.html#Observation.valueCodeableConcept" title="todo.">valueCodeableConcept</a>
            <a name="Observation.valueCodeableConcept"></a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy" />
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">
            <a href="http://hl7.org/fhir/datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Low risk | High risk<br /><span style="font-weight:bold">Binding: </span><a href="https://r.details.loinc.org/AnswerList/LL2353-2.html">LOINC Answer List LL2353-2</a> (<a href="http://hl7.org/fhir/terminologies.html#extensible" title="To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.">extensible</a>)</td>
        </tr>
        <tr>
          <td colspan="5" class="hierarchy">
            <br />
            <a href="http://hl7.org/fhir/formats.html#table" title="Legend for this format">
              <img src="http://hl7.org/fhir/help16.png" alt="doco" style="background-color: inherit" /> Documentation for this format</a>
          </td>
        </tr>
      </table>
    </div>
  </text>
  <url value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medication-high-risk" />
  <version value="1.0.0" />
  <name value="MedicationHighRisk" />
  <title value="Medication High Risk" />
  <status value="draft" />
  <experimental value="false" />
  <date value="2017-05-20T00:00:00+00:00" />
  <publisher value="HL7 Clinical Genomics WG" />
  <description value="Observation-related profiles" />
  <fhirVersion value="4.0.1" />
  <mapping>
    <identity value="v2-cg-results" />
    <uri value="http://unknown.org/V2-CG-Results" />
    <name value="V2-CG-Results" />
  </mapping>
  <mapping>
    <identity value="workflow" />
    <uri value="http://hl7.org/fhir/workflow" />
    <name value="Workflow Pattern" />
  </mapping>
  <mapping>
    <identity value="sct-concept" />
    <uri value="http://snomed.info/conceptdomain" />
    <name value="SNOMED CT Concept Domain Binding" />
  </mapping>
  <mapping>
    <identity value="v2" />
    <uri value="http://hl7.org/v2" />
    <name value="HL7 v2 Mapping" />
  </mapping>
  <mapping>
    <identity value="rim" />
    <uri value="http://hl7.org/v3" />
    <name value="RIM Mapping" />
  </mapping>
  <mapping>
    <identity value="w5" />
    <uri value="http://hl7.org/fhir/fivews" />
    <name value="FiveWs Pattern Mapping" />
  </mapping>
  <mapping>
    <identity value="sct-attr" />
    <uri value="http://snomed.org/attributebinding" />
    <name value="SNOMED CT Attribute Binding" />
  </mapping>
  <kind value="resource" />
  <abstract value="false" />
  <type value="Observation" />
  <baseDefinition value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medication-implication" />
  <derivation value="constraint" />
  <snapshot />
  <differential>
    <element id="Observation">
      <path value="Observation" />
      <short value="Medication High Risk" />
      <definition value="Finding of whether the patient has a high-risk allele for a particular medication." />
      <mustSupport value="false" />
    </element>
    <element id="Observation.code">
      <path value="Observation.code" />
      <short value="Genomic variation's effect on high-risk allele" />
      <definition value="todo." />
      <min value="1" />
      <max value="1" />
      <type>
        <code value="CodeableConcept" />
      </type>
      <patternCodeableConcept>
        <coding>
          <system value="http://loinc.org" />
          <code value="83009-1" />
        </coding>
      </patternCodeableConcept>
      <mustSupport value="false" />
    </element>
    <element id="Observation.valueCodeableConcept">
      <path value="Observation.valueCodeableConcept" />
      <short value="Low risk | High risk" />
      <definition value="todo." />
      <min value="1" />
      <max value="1" />
      <type>
        <code value="CodeableConcept" />
      </type>
      <mustSupport value="false" />
      <binding>
        <strength value="extensible" />
        <description value="High Risk Allele values" />
        <valueSet value="http://loinc.org/vs/LL2353-2" />
      </binding>
      <mapping>
        <identity value="v2-cg-results" />
        <map value="F.5" />
      </mapping>
    </element>
  </differential>
</StructureDefinition>