Name Flags Card. Type Description & Constraints doco
. . Observation 0 .. * Implication
. . . RelatedArtifact 0..* RelatedArtifact Citations and supporting info
URL: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact
. . . note 0 .. * Annotation Details
. . . derivedFrom 1 .. * (Slice Definition) Slice: Unordered, Open by pattern:resolve().code
. . . . derivedFrom:genotype 0..* Reference(Genotype)
. . . . derivedFrom:haplotype 0..* Reference(Haplotype)
. . . . derivedFrom:variant 0..* Reference(Variant)
. . . component 0 .. * (Slice Definition) Slice: Unordered, Open by pattern:code
. . . . component:evidence-level 0..1 BackboneElement Level of Evidence
. . . . . code 1..1 CodeableConcept Required Pattern: At least the following
. . . . . . coding 1..* Coding Code defined by a terminology system
Fixed Value: (complex)
. . . . . . . system 1..1 uri Identity of the terminology system
Fixed Value: http://loinc.org
. . . . . . . code 1..1 code Symbol in syntax defined by the system
Fixed Value: 93044-6
. . . . . value[x] 1..1 CodeableConcept Binding: LOINC Answer List LL5356-2 (preferred)

doco Documentation for this format
<status value="draft" /> <experimental value="false" /> <date value="2017-05-20T00:00:00+00:00" /> <publisher value="HL7 Clinical Genomics WG" /> <description value="Observation-related profiles" /> <fhirVersion value="4.0.1" /> <mapping> <identity value="workflow" /> <uri value="http://hl7.org/fhir/workflow" /> <name value="Workflow Pattern" /> </mapping> <mapping> <identity value="sct-concept" /> <uri value="http://snomed.info/conceptdomain" /> <name value="SNOMED CT Concept Domain Binding" /> </mapping> <mapping> <identity value="v2" /> <uri value="http://hl7.org/v2" /> <name value="HL7 v2 Mapping" /> </mapping> <mapping> <identity value="rim" /> <uri value="http://hl7.org/v3" /> <name value="RIM Mapping" /> </mapping> <mapping> <identity value="w5" /> <uri value="http://hl7.org/fhir/fivews" /> <name value="FiveWs Pattern Mapping" /> </mapping> <mapping> <identity value="sct-attr" /> <uri value="http://snomed.org/attributebinding" /> <name value="SNOMED CT Attribute Binding" /> </mapping> <kind value="resource" /> <abstract value="false" /> <type value="Observation" /> <baseDefinition value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-base" /> <derivation value="constraint" /> <snapshot /> <differential> <element id="Observation"> <path value="Observation" /> <short value="Implication" /> <definition value="Abstract profile for observations describing the implication of one or more genetic observations." /> <mustSupport value="false" /> </element> <element id="Observation.extension:RelatedArtifact"> <path value="Observation.extension" /> <sliceName value="RelatedArtifact" /> <short value="Citations and supporting info" /> <definition value="References to literature that supports the implication assertion." /> <min value="0" /> <max value="*" /> <type> <code value="Extension" /> <profile value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact" /> </type> <mustSupport value="false" /> </element> <element id="Observation.note"> <path value="Observation.note" /> <short value="Details" /> <definition value="Additional commentary, qualification or other information about the genetic implication." /> <mustSupport value="false" /> </element> <element id="Observation.derivedFrom"> <path value="Observation.derivedFrom" /> <slicing> <discriminator> <type value="pattern" /> <path value="resolve().code" /> </discriminator> <rules value="open" /> </slicing> <definition value="variant, haplotype, or MolecularSequence from which this implication is derived." /> <min value="1" /> <max value="*" /> <mustSupport value="false" /> </element> <element id="Observation.derivedFrom:genotype"> <path value="Observation.derivedFrom" /> <sliceName value="genotype" /> <definition value="Genotype from which this implication is derived." /> <min value="0" /> <max value="*" /> <type> <code value="Reference" /> <targetProfile value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genotype" /> </type> <mustSupport value="false" /> </element> <element id="Observation.derivedFrom:haplotype"> <path value="Observation.derivedFrom" /> <sliceName value="haplotype" /> <definition value="Haplotype from which this implication is derived." /> <min value="0" /> <max value="*" /> <type> <code value="Reference" /> <targetProfile value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/haplotype" /> </type> <mustSupport value="false" /> </element> <element id="Observation.derivedFrom:variant"> <path value="Observation.derivedFrom" /> <sliceName value="variant" /> <definition value="Variant from which this implication is derived." /> <min value="0" /> <max value="*" /> <type> <code value="Reference" /> <targetProfile value="http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant" /> </type> <mustSupport value="false" /> </element> <element id="Observation.component"> <path value="Observation.component" /> <slicing> <discriminator> <type value="pattern" /> <path value="code" /> </discriminator> <rules value="open" /> </slicing> <mustSupport value="false" /> </element> <element id="Observation.component:evidence-level"> <path value="Observation.component" /> <sliceName value="evidence-level" /> <short value="Level of Evidence" /> <definition value="Indicates the quality and type of evidence supporting this assertion. E.g. terms from ACMG guidelines for the interpretation of sequence variants, CPIC Clinical Annotation levels of Evidence." /> <min value="0" /> <max value="1" /> <mustSupport value="false" /> </element> <element id="Observation.component:evidence-level.code"> <path value="Observation.component.code" /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> <patternCodeableConcept> <coding> <system value="http://loinc.org" /> <code value="93044-6" /> </coding> </patternCodeableConcept> <mustSupport value="false" /> </element> <element id="Observation.component:evidence-level.value[x]"> <path value="Observation.component.value[x]" /> <min value="1" /> <max value="1" /> <type> <code value="CodeableConcept" /> </type> <mustSupport value="false" /> <binding> <strength value="preferred" /> <description value="ACMG Level of evidence" /> <valueSet value="http://loinc.org/vs/LL5356-2" /> </binding> </element> </differential> </StructureDefinition>