{ "resourceType": "StructureDefinition", "id": "implication", "meta": { "lastUpdated": "2019-12-20T21:25:33.25+00:00" }, "text": { "status": "generated", "div": "
NameFlagsCard.TypeDescription & Constraints\"doco\"
\".\"\".\"Observation0..*Implication
\".\"\".\"\".\"RelatedArtifact0..*RelatedArtifactCitations and supporting info
URL: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact
\".\"\".\"\".\"note0..*AnnotationDetails
\".\"\".\"\".\"derivedFrom1..*(Slice Definition)Slice: Unordered, Open by pattern:resolve().code
\".\"\".\"\".\"\".\"derivedFrom:genotype0..*Reference(Genotype)
\".\"\".\"\".\"\".\"derivedFrom:haplotype0..*Reference(Haplotype)
\".\"\".\"\".\"\".\"derivedFrom:variant0..*Reference(Variant)
\".\"\".\"\".\"component0..*(Slice Definition)Slice: Unordered, Open by pattern:code
\".\"\".\"\".\"\".\"component:evidence-level0..1BackboneElementLevel of Evidence
\".\"\".\"\".\"\".\"\".\"code1..1CodeableConceptRequired Pattern: At least the following
\".\"\".\"\".\"\".\"\".\"\".\"coding1..*CodingCode defined by a terminology system
Fixed Value: (complex)
\".\"\".\"\".\"\".\"\".\"\".\"\".\"system1..1uriIdentity of the terminology system
Fixed Value: http://loinc.org
\".\"\".\"\".\"\".\"\".\"\".\"\".\"code1..1codeSymbol in syntax defined by the system
Fixed Value: 93044-6
\".\"\".\"\".\"\".\"\".\"value[x]1..1CodeableConceptBinding: LOINC Answer List LL5356-2 (preferred)

\"doco\" Documentation for this format
" }, "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/implication", "version": "1.0.0", "name": "Implication", "title": "Implication", "status": "draft", "experimental": false, "date": "2017-05-20T00:00:00+00:00", "publisher": "HL7 Clinical Genomics WG", "description": "Observation-related profiles", "fhirVersion": "4.0.1", "mapping": [ { "identity": "workflow", "uri": "http://hl7.org/fhir/workflow", "name": "Workflow Pattern" }, { "identity": "sct-concept", "uri": "http://snomed.info/conceptdomain", "name": "SNOMED CT Concept Domain Binding" }, { "identity": "v2", "uri": "http://hl7.org/v2", "name": "HL7 v2 Mapping" }, { "identity": "rim", "uri": "http://hl7.org/v3", "name": "RIM Mapping" }, { "identity": "w5", "uri": "http://hl7.org/fhir/fivews", "name": "FiveWs Pattern Mapping" }, { "identity": "sct-attr", "uri": "http://snomed.org/attributebinding", "name": "SNOMED CT Attribute Binding" } ], "kind": "resource", "abstract": false, "type": "Observation", "baseDefinition": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-base", "derivation": "constraint", "snapshot": {}, "differential": { "element": [ { "id": "Observation", "path": "Observation", "short": "Implication", "definition": "Abstract profile for observations describing the implication of one or more genetic observations.", "mustSupport": false }, { "id": "Observation.extension:RelatedArtifact", "path": "Observation.extension", "sliceName": "RelatedArtifact", "short": "Citations and supporting info", "definition": "References to literature that supports the implication assertion.", "min": 0, "max": "*", "type": [ { "code": "Extension", "profile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact" ] } ], "mustSupport": false }, { "id": "Observation.note", "path": "Observation.note", "short": "Details", "definition": "Additional commentary, qualification or other information about the genetic implication.", "mustSupport": false }, { "id": "Observation.derivedFrom", "path": "Observation.derivedFrom", "slicing": { "discriminator": [ { "type": "pattern", "path": "resolve().code" } ], "rules": "open" }, "definition": "variant, haplotype, or MolecularSequence from which this implication is derived.", "min": 1, "max": "*", "mustSupport": false }, { "id": "Observation.derivedFrom:genotype", "path": "Observation.derivedFrom", "sliceName": "genotype", "definition": "Genotype from which this implication is derived.", "min": 0, "max": "*", "type": [ { "code": "Reference", "targetProfile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genotype" ] } ], "mustSupport": false }, { "id": "Observation.derivedFrom:haplotype", "path": "Observation.derivedFrom", "sliceName": "haplotype", "definition": "Haplotype from which this implication is derived.", "min": 0, "max": "*", "type": [ { "code": "Reference", "targetProfile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/haplotype" ] } ], "mustSupport": false }, { "id": "Observation.derivedFrom:variant", "path": "Observation.derivedFrom", "sliceName": "variant", "definition": "Variant from which this implication is derived.", "min": 0, "max": "*", "type": [ { "code": "Reference", "targetProfile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant" ] } ], "mustSupport": false }, { "id": "Observation.component", "path": "Observation.component", "slicing": { "discriminator": [ { "type": "pattern", "path": "code" } ], "rules": "open" }, "mustSupport": false }, { "id": "Observation.component:evidence-level", "path": "Observation.component", "sliceName": "evidence-level", "short": "Level of Evidence", "definition": "Indicates the quality and type of evidence supporting this assertion. E.g. terms from ACMG guidelines for the interpretation of sequence variants, CPIC Clinical Annotation levels of Evidence.", "min": 0, "max": "1", "mustSupport": false }, { "id": "Observation.component:evidence-level.code", "path": "Observation.component.code", "min": 1, "max": "1", "type": [ { "code": "CodeableConcept" } ], "patternCodeableConcept": { "coding": [ { "system": "http://loinc.org", "code": "93044-6" } ] }, "mustSupport": false }, { "id": "Observation.component:evidence-level.value[x]", "path": "Observation.component.value[x]", "min": 1, "max": "1", "type": [ { "code": "CodeableConcept" } ], "mustSupport": false, "binding": { "strength": "preferred", "description": "ACMG Level of evidence", "valueSet": "http://loinc.org/vs/LL5356-2" } } ] } }