{
  "resourceType": "StructureDefinition",
  "url": "https://fhir.nmdp.org/ig/HlaAntibodyReport/StructureDefinition/hla-immunoassay-interpretation",
  "version": "0.2.0",
  "name": "HLAImmunoassayInterpretation",
  "title": "HLA Immunoassay Interpretation",
  "status": "draft",
  "publisher": "NMDP",
  "contact": [
    {
      "name": "David Wroe",
      "telecom": [
        {
          "system": "email",
          "value": "fhir@nmdp.org",
          "use": "work"
        }
      ]
    }
  ],
  "description": "# HLA Immunoassay Interpretation\r\n\r\nExtension of HL7 observation to capture interpretation attributes specific to solid-phase immunoassay test results.\r\n\r\nAn HLA Antibody Assay Interpretation contains the overall human interpretation of an entire assay.\r\nThis includes which antigens/specificities are determined to be positive or negative.\r\n\r\n## Components of this observation:\r\n------------------------------------\r\n* **interpretation-context**: “Clinical Interpretation”\r\n* **reject-assay**: Boolean if the assay was rejected or not.\r\n* **reject-reason**: Reason for assay rejection\r\n* **failure-code**: Failure code generated for assay\r\n* **positive-specificities**: multi-locus HLA GLstring of all loci and alleles considered positive\r\n* **questionable-specificities**: multi-locus HLA GLstring of all loci and alleles considered questionable\r\n* **negative-specificities**: multi-locus HLA GLstring of all loci and alleles considered negative",
  "purpose": "An HLA Antibody Assay Interpretation contains the overall human interpretation of an entire assay.\r\nThis includes which antigens/specificities are determined to be positive, negative or questionable.",
  "fhirVersion": "4.0.1",
  "kind": "resource",
  "abstract": false,
  "type": "Observation",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Observation",
  "derivation": "constraint",
  "differential": {
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        "mustSupport": true
      },
      {
        "id": "Observation.focus",
        "path": "Observation.focus",
        "max": "0"
      },
      {
        "id": "Observation.encounter",
        "path": "Observation.encounter",
        "max": "0"
      },
      {
        "id": "Observation.performer",
        "path": "Observation.performer",
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      },
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        "id": "Observation.performer.reference",
        "path": "Observation.performer.reference",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Observation.interpretation",
        "path": "Observation.interpretation",
        "max": "0"
      },
      {
        "id": "Observation.bodySite",
        "path": "Observation.bodySite",
        "max": "0"
      },
      {
        "id": "Observation.specimen",
        "path": "Observation.specimen",
        "mustSupport": true
      },
      {
        "id": "Observation.specimen.reference",
        "path": "Observation.specimen.reference",
        "min": 1
      },
      {
        "id": "Observation.referenceRange",
        "path": "Observation.referenceRange",
        "max": "0"
      },
      {
        "id": "Observation.component",
        "path": "Observation.component",
        "slicing": {
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            {
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              "path": "$this"
            }
          ],
          "rules": "open"
        }
      },
      {
        "id": "Observation.component:assay-rejected",
        "path": "Observation.component",
        "sliceName": "assay-rejected",
        "label": "assay-rejected",
        "max": "1",
        "mustSupport": true
      },
      {
        "id": "Observation.component:assay-rejected.code.coding.system",
        "path": "Observation.component.code.coding.system",
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        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "valueSet": "http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes"
        }
      },
      {
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        "path": "Observation.component.code.coding.code",
        "min": 1,
        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "valueSet": "http://fhir.nmdp.org/terminologyfhir/ValueSet//hla-immuno-assay-rejected-reason"
        }
      },
      {
        "id": "Observation.component:assay-failure-code",
        "path": "Observation.component",
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        "label": "assay-failure-code",
        "max": "1",
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        "mustSupport": true,
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          "valueSet": "http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes"
        }
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        "binding": {
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        "mustSupport": true
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        "path": "Observation.component.code.coding.system",
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          "valueSet": "http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes"
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}