{ "resourceType": "StructureDefinition", "id": "c5dba487-62ea-4927-a6a7-58444235eba9", "meta": { "lastUpdated": "2021-11-10T13:30:20.73+00:00" }, "url": "https://fhir.simplifier.net/Histo-AI/StructureDefinition", "name": "HistoAI", "status": "draft", "date": "2021-10-06T10:27:25.9408563+00:00", "fhirVersion": "4.0.1", "kind": "logical", "abstract": false, "type": "https://simplifier.net/Histo-AI/HistoAI", "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Element", "derivation": "specialization", "differential": { "element": [ { "id": "HistoAI", "path": "HistoAI", "min": 0, "max": "*", "type": [ { "code": "Element" } ] }, { "id": "HistoAI.Patient", "path": "HistoAI.Patient", "label": "Patient", "short": "Individual patient in Histo-AI study", "definition": "Individual patient in Histo-AI study.", "alias": [ "Individual" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.subjectId", "path": "HistoAI.Patient.subjectId", "label": "Subject ID", "short": "Anonymized id of this patient", "definition": "Unique Study record number. This ID will be computer generated and randomly assigned to each subject/record. Can if needed be linked to hospital patient number or notary number through data manager with key. Do NOT use institution specific ID.", "min": 1, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] }, { "id": "HistoAI.Patient.gender", "path": "HistoAI.Patient.gender", "label": "Gender", "short": "male | female | other | unknown", "definition": "Administrative Gender - the gender that the patient is considered to have for administration and record keeping purposes.", "comment": "The gender might not match the biological sex as determined by genetics or the individual's preferred identification.", "requirements": "Needed for identification of the individual, in combination with (at least) name and birth date.", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.ageAtPrimaryDiagnosis", "path": "HistoAI.Patient.ageAtPrimaryDiagnosis", "label": "Age at Primary Diagnosis", "short": "The age at first primary diagnosis for the individual", "definition": "The age at first primary diagnosis for the individual.", "comment": "At least an estimated year should be provided as a guess if the real DOB is unknown There is a standard extension \"patient-birthTime\" available that should be used where Time is required (such as in maternity/infant care systems).", "requirements": "Age of the individual drives many clinical processes.", "min": 0, "max": "1", "type": [ { "code": "Age", "profile": [ "http://hl7.org/fhir/StructureDefinition/Age" ] } ] }, { "id": "HistoAI.Patient.ageAtDeath", "path": "HistoAI.Patient.ageAtDeath", "label": "Age at Death", "short": "The age at death for the individual, if applicable", "definition": "The age at death for the individual, if applicable.", "alias": [ "Death Date", "Date of Death", "Deseased Date" ], "min": 0, "max": "1", "type": [ { "code": "Age", "profile": [ "http://hl7.org/fhir/StructureDefinition/Age" ] } ] }, { "id": "HistoAI.Patient.causeOfDeath", "path": "HistoAI.Patient.causeOfDeath", "label": "Cause of Death", "min": 0, "max": "1", "type": [ { "code": "string", "profile": [ "http://hl7.org/fhir/StructureDefinition/string" ] } ] }, { "id": "HistoAI.Patient.hospitalName", "path": "HistoAI.Patient.hospitalName", "label": "Hospital Name", "definition": "Nameofhospital,cityintheNetherlands", "min": 0, "max": "*", "type": [ { "code": "string", "profile": [ "http://hl7.org/fhir/StructureDefinition/string" ] } ] }, { "id": "HistoAI.Patient.Pathology", "path": "HistoAI.Patient.Pathology", "label": "Pathology", "short": "Pathology report of this patient", "definition": "Pathology report of this patient, primarily from Palga (nation wide Dutch pathology record system)", "comment": "Indexed with T number", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Pathology.palgaId", "path": "HistoAI.Patient.Pathology.palgaId", "label": "Palga ID", "short": "Palga identifier", "definition": "Report name in Palga;\r\nTissue number in Tumor Registry;\r\nAn_number of Analysis in Lab Management System.", "comment": "Startswith 'T', 'C' or 'S', then two digits as the year, then dash `-`, followed by 5 digits. regex: /[TCS]\\d{2}-\\d{5}/\r\nFor the latter 5 digits:\r\nInternal tissue number usually starts with 00;\r\nExternal tissue number usually starts with 2x.", "alias": [ "T number", "Tissue number", "Onderzoeker nummer", "An_number", "rapnaam" ], "min": 1, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ], "patternIdentifier": { "use": "usual", "type": { "coding": [ { "system": "http://hl7.org/fhir/StructureDefinition/regex", "code": "[TCS]\\d{2}-\\d{5}" } ] } }, "example": [ { "label": "Tissue number", "valueIdentifier": { "use": "usual", "value": "T20-00123" } } ] }, { "id": "HistoAI.Patient.Pathology.externalPalgaId", "path": "HistoAI.Patient.Pathology.externalPalgaId", "label": "External Palga ID", "short": "External hospital tissue number", "definition": "Exteral hospital - Tissue number in Nation Wide Dutch Pathology Record system", "comment": "currently not in the DWH. ask Wouter or Dennis", "min": 0, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] }, { "id": "HistoAI.Patient.Pathology.sampleAcquisitionClass", "path": "HistoAI.Patient.Pathology.sampleAcquisitionClass", "label": "Tissue sample acquisition class", "short": "Tissue sample acquisition class", "definition": "Tissue sample acquisition class: (palga code)\r\nbiopsy = hollow needle and take small part of tissue;\r\nexision = part of an organ;\r\nresection = whole organ removal", "comment": "05.01 Sample_Class in Data life cycle.\r\ndata source: [LMS].[TissueAcquisiton]", "alias": [ "SampleClass" ], "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.sampleRemovalType", "path": "HistoAI.Patient.Pathology.sampleRemovalType", "label": "Sample Removal Type", "short": "Type of tissue sample removal", "definition": "Type of tissue sample removal: primary / recurrence / metastasis, directly related with tissure number", "comment": "combination of: \r\n05.02 Sample_registration Sample_site_Prim\r\n05.03 Sample_registration Sample_site_Met", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.sampleRemovalIndicator", "path": "HistoAI.Patient.Pathology.sampleRemovalIndicator", "label": "Sample Removal Timing", "short": "Indicate tissure sample removal before or after treatment", "definition": "Indicate tissure sample removal timing: before or after treatment.", "comment": "05.04 Sample_removal_ind Timeofbiopsytaken(pre-oraftertreatment) in Data life cycle", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.sampleRemovalDate", "path": "HistoAI.Patient.Pathology.sampleRemovalDate", "label": "Sample Removal Date", "short": "Date of the tissue sample removal", "definition": "Date of the tissue sample removal", "alias": [ "monsterdatum", "DissectionDate" ], "min": 0, "max": "1", "type": [ { "code": "dateTime", "profile": [ "http://hl7.org/fhir/StructureDefinition/dateTime" ] } ] }, { "id": "HistoAI.Patient.Pathology.ffpeCassette", "path": "HistoAI.Patient.Pathology.ffpeCassette", "label": "FFPE Cassette", "short": "FFPE Cassette", "definition": "FFPE (Formalin-Fixed Paraffin-Embedded) Cassette available for this tissue", "comment": "Palga record, should match with specimen containers in LMS", "min": 0, "max": "*", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container", "path": "HistoAI.Patient.Pathology.Container", "label": "Container", "short": "Container of tissue specimen of this pathology analysis", "definition": "Container of tissue specimen of this pathology analysis.", "alias": [ "Block", "Specimen" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Pathology.Container.blockNumber", "path": "HistoAI.Patient.Pathology.Container.blockNumber", "label": "Sample Class", "short": "Identifier of the container block", "definition": "Identifier of the container block. Combination of sending number + cassette number.", "comment": "[LMS].[Specimen].[Number]+[LMS].[Container].[Number]\r\nDepending on enumerateType , can be alpha+number or roman+number: A3 or IV4", "min": 0, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide", "path": "HistoAI.Patient.Pathology.Container.SampleSlide", "label": "Sample Slide", "short": "The sample slide being digitized", "definition": "The sample slide being digitized.", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.staining", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.staining", "label": "Staining", "short": "The staining type of the sample slide", "definition": "The staining type of the sample slide: HE, CD3, CD8, PDL1, etc.", "comment": "see LMS.Staing for the code", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide", "label": "Scanned Slide", "short": "Digitized slide of the tisse", "definition": "Digitized slide of the tisse with certain staining. \r\nMetadata to link with the WSI in image storage.", "comment": "This can be in another database specifically for AI research", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.imageId", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.imageId", "label": "Image ID", "short": "Global identifier of the WSI", "definition": "Global identifier of the Whole Slide Image", "comment": "Generated UUID for each image.", "alias": [ "WSI ID" ], "min": 1, "max": "1", "type": [ { "code": "uuid", "profile": [ "http://hl7.org/fhir/StructureDefinition/uuid" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.scannerModel", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.scannerModel", "label": "Scanner Model", "short": "Model of the scanner", "definition": "Model of the scanner: 3DHistech, Aperio, Philips, etc.", "min": 0, "max": "1", "type": [ { "code": "string", "profile": [ "http://hl7.org/fhir/StructureDefinition/string" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileLocation", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileLocation", "label": "File Location", "short": "Description of the file location in Image Storage", "definition": "Description of the file location Image Storage. Which image storge? Where is it physically located?", "min": 0, "max": "1", "type": [ { "code": "string", "profile": [ "http://hl7.org/fhir/StructureDefinition/string" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileName", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileName", "label": "File Name", "short": "The filename of the digitized slide", "definition": "The filename of the digitized slide", "min": 0, "max": "1", "type": [ { "code": "string", "profile": [ "http://hl7.org/fhir/StructureDefinition/string" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileFormat", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileFormat", "label": "File Format", "short": "Format of the image file", "definition": "Format of the image file: svs, tiff, etc.", "alias": [ "File Extension", "File Type" ], "min": 0, "max": "1", "type": [ { "code": "Reference" } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileSize", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.fileSize", "label": "File Size", "short": "File size in byte", "definition": "File size in byte", "min": 0, "max": "1", "type": [ { "code": "integer", "profile": [ "http://hl7.org/fhir/StructureDefinition/integer" ] } ] }, { "id": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.symbolicLink", "path": "HistoAI.Patient.Pathology.Container.SampleSlide.ScannedSlide.symbolicLink", "label": "Symbolic Link", "short": "Link(s) to the file storage of this WSI", "definition": "Link(s) to the file storage of this Whole Slide Image", "min": 0, "max": "*", "type": [ { "code": "uri", "profile": [ "http://hl7.org/fhir/StructureDefinition/uri" ] } ] }, { "id": "HistoAI.Patient.Pathology.ImmunoHistoChemistry", "path": "HistoAI.Patient.Pathology.ImmunoHistoChemistry", "label": "ImmunoHistoChemistry", "short": "IHC bio-markers", "definition": "The laboratory method that uses antibodies to check for certain antigens (bio-markers) in a sample of tissue.", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Pathology.ImmunoHistoChemistry.markerName", "path": "HistoAI.Patient.Pathology.ImmunoHistoChemistry.markerName", "label": "Marker Name", "short": "Name of the biomarker", "definition": "Name of the biomarker (antigens)", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.ImmunoHistoChemistry.markerPercentage", "path": "HistoAI.Patient.Pathology.ImmunoHistoChemistry.markerPercentage", "label": "Marker Percentage", "short": "Percentage of positive tumor cells for this marker", "definition": "Percentage of positive tumor cells for this marker immunohistochemistry.", "min": 0, "max": "1", "type": [ { "code": "Ratio", "profile": [ "http://hl7.org/fhir/StructureDefinition/Ratio" ] } ] }, { "id": "HistoAI.Patient.Pathology.tumorGrade", "path": "HistoAI.Patient.Pathology.tumorGrade", "label": "Tumor Grade", "short": "Grade of the tumour", "definition": "Grade of the tumour asassigned by the reporting tumour grading system in Palga.", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.tumorHistologicalType", "path": "HistoAI.Patient.Pathology.tumorHistologicalType", "label": "Tumor Histological Type", "code": [ { "system": "http://terminology.hl7.org/CodeSystem/icd-o-3" } ], "short": "The code to represent the histology (morphology) of neoplasms", "definition": "The code to represent the histology (morphology) of neoplasms that is usually obtained from a pathology report, according to the International Classification of Diseases for Oncology, 3rdEdition(WHO ICD-O-3). RefertotheICD-O", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Pathology.PathologyReport", "path": "HistoAI.Patient.Pathology.PathologyReport", "label": "Pathology Report", "short": "Pathology report in Palga", "definition": "Pathology report (free text) in Palga", "comment": "Aardmateriaal, Klinischegegevens, Immuunhistochemie, Macroscopie, Microscropie, Conclusie", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Radiology", "path": "HistoAI.Patient.Radiology", "label": "Radiology", "short": "Radiology report of this patient", "definition": "Radiology report of this patient, primarily from PACS (Picture archiving and communication system)", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Genomics", "path": "HistoAI.Patient.Genomics", "label": "Genomics", "short": "Genomics report of this patient", "definition": "Genomics report of this patient, primarily from MolPa (molecular pathology database) and GCF (Genomics core facility)", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor", "path": "HistoAI.Patient.Tumor", "label": "Tumor", "short": "Tumor records of this patient", "definition": "Tumor records of this patient in Tumor Registry. Only primary tumor.", "comment": "Indexed with (patientId, tumorSys)", "alias": [ "Tumour", "Cancer", "Disease" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor.tumorId", "path": "HistoAI.Patient.Tumor.tumorId", "label": "Tumor ID", "short": "Global unique tumor identifier", "definition": "Uniquely generated selected primary cancer tumor number per patient at Scientific administration of the Netherlands Cancer Institute.", "comment": "Presented in the code book \"01.09 Tumour_ID\". Not in tumor registry. \r\nThis UUID will be generated during patient anonymisation process.", "min": 1, "max": "1", "type": [ { "code": "uuid", "profile": [ "http://hl7.org/fhir/StructureDefinition/uuid" ] } ] }, { "id": "HistoAI.Patient.Tumor.tumorSys", "path": "HistoAI.Patient.Tumor.tumorSys", "label": "Tumor sys", "short": "Tumorsys code in Tumor Registry", "definition": "System variable for linking with all tumor-related tables in tumor registry.\r\nFirst primary tumor: Tumorsys=1\r\nSecond primary tumor: Tumorsys=2", "comment": "Tumor_sys is part of the PrimaryKey (together with with PatientId) for all Tumor Registry tables in dataware house. TRTU_Tumorsys_code", "alias": [ "TRTU_Tumorsys_code" ], "min": 0, "max": "1", "type": [ { "code": "integer", "profile": [ "http://hl7.org/fhir/StructureDefinition/integer" ] } ] }, { "id": "HistoAI.Patient.Tumor.diagnosisDate", "path": "HistoAI.Patient.Tumor.diagnosisDate", "label": "Diagnosis Date", "short": "Date of primary diagnosis of the tumor", "definition": "Date of primary diagnosis of the tumor.", "comment": "If patient has had multiple cancer diagnoses, should be able to select the data only for the diagnosis thought to be associated with the metastatic disease.", "min": 0, "max": "1", "type": [ { "code": "dateTime", "profile": [ "http://hl7.org/fhir/StructureDefinition/dateTime" ] } ] }, { "id": "HistoAI.Patient.Tumor.diagnosisCode", "path": "HistoAI.Patient.Tumor.diagnosisCode", "label": "DiagnosisCode", "code": [ { "system": "http://hl7.org/fhir/sid/icd-10" } ], "short": "Primary cancer type code ICD-10", "definition": "The code to represent the cancer type using the WHO ICD-10 code classification.", "comment": "The code to represent the cancer type using the WHO ICD-10 code classification.\r\n(https://icd.who.int/browse10/2019/en)", "alias": [ "Cancer Type", "Primary Type" ], "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/sid/icd-10" ] } ] }, { "id": "HistoAI.Patient.Tumor.diagnosisDescription", "path": "HistoAI.Patient.Tumor.diagnosisDescription", "label": "Primary Site", "short": "Diagnosis Description", "definition": "The text term used to describe the primary site of disease, as categorized by the WorldHealthOrganization's (WHO) International Classification of Diseasesfor Oncology (ICD-O). This categorization groups cases into general categories.", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Tumor.ClinicalStage", "path": "HistoAI.Patient.Tumor.ClinicalStage", "label": "Clinical Stage", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-stage-group" } ], "short": "AJCC clinical stage group", "definition": "AJCC clinical stage group, https://cancerstaging.org.", "alias": [ "TNM clinical stage" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ], "mapping": [ { "identity": "TNMClinicalStageGroup", "map": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-stage-group" } ] }, { "id": "HistoAI.Patient.Tumor.ClinicalStage.cT", "path": "HistoAI.Patient.Tumor.ClinicalStage.cT", "label": "cT", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-primary-tumor-category" } ], "short": "TNM Clinical Primary Tumor Category", "definition": "TNM Clinical Primary Tumor Category", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-primary-tumor-category" ] } ] }, { "id": "HistoAI.Patient.Tumor.ClinicalStage.cN", "path": "HistoAI.Patient.Tumor.ClinicalStage.cN", "label": "cN", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-regional-nodes-category" } ], "short": "TNM Clinical Regional Nodes Category", "definition": "TNM Clinical Regional Nodes Category", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-regional-nodes-category" ] } ] }, { "id": "HistoAI.Patient.Tumor.ClinicalStage.cM", "path": "HistoAI.Patient.Tumor.ClinicalStage.cM", "label": "cM", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-distant-metastases-category" } ], "short": "TNM Clinical Distant Metastases Category", "definition": "TNM Clinical Distant Metastases Category", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-clinical-distant-metastases-category" ] } ] }, { "id": "HistoAI.Patient.Tumor.PathologicalStage", "path": "HistoAI.Patient.Tumor.PathologicalStage", "label": "Pathological Stage", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-stage-group" } ], "short": "AJCC pathological stage group", "definition": "AJCC pathological stage group, https://cancerstaging.org.", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ], "mapping": [ { "identity": "TNMPathologicalStageGroup", "map": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-stage-group" } ] }, { "id": "HistoAI.Patient.Tumor.PathologicalStage.pT", "path": "HistoAI.Patient.Tumor.PathologicalStage.pT", "label": "pT", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-distant-metastases-category" } ], "short": "TNM Pathological Primary Tumor Category", "definition": "TNM Pathological Primary Tumor Category", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-distant-metastases-category" ] } ] }, { "id": "HistoAI.Patient.Tumor.PathologicalStage.pN", "path": "HistoAI.Patient.Tumor.PathologicalStage.pN", "label": "pN", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-distant-metastases-category" } ], "short": "TNM Pathological Regional Nodes Category", "definition": "TNM Pathological Regional Nodes Category", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-distant-metastases-category" ] } ] }, { "id": "HistoAI.Patient.Tumor.PathologicalStage.pM", "path": "HistoAI.Patient.Tumor.PathologicalStage.pM", "label": "pM", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-distant-metastases-category" } ], "short": "TNM Pathological Distant Metastases Category", "definition": "TNM Pathological Distant Metastases Category", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-tnm-pathological-distant-metastases-category" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization", "path": "HistoAI.Patient.Tumor.Localization", "label": "Localization", "short": "Metastasis of this tumor", "definition": "Diagnosis of distant metastatic of this cancer of this patient.", "comment": "Derived from data in Tumorregistratie.", "alias": [ "Localisatie", "Distant metastasis" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor.Localization.localizationDate", "path": "HistoAI.Patient.Tumor.Localization.localizationDate", "label": "Localization Date", "short": "Date of diagnosis of this localization", "definition": "Date of diagnosis of this localization.", "alias": [ "Date_First_metastasis", "Date_Local_ipsilat_recurrence", "Date_Contralateral", "Date_Regional_recurrence" ], "min": 0, "max": "1", "type": [ { "code": "dateTime", "profile": [ "http://hl7.org/fhir/StructureDefinition/dateTime" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization.metastasisSiteCode", "path": "HistoAI.Patient.Tumor.Localization.metastasisSiteCode", "label": "Metastasis Site Code", "code": [ { "system": "http://hl7.org/fhir/sid/icd-10" } ], "short": "ICD10 code of location of the metastasis of this tumor", "definition": "ICD10 code of location/site of the metastasis of this tumor of this patient.", "comment": "04.09 Follow_up Date_First_metastasis\r\nnot always in [TRLK_Lokalisatie_code], should lookup TRTU to refer to primary tumor\r\nref: DLC Date_Progessive_Disease_after_treatment_metast1", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/sid/icd-10" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization.metastasisSiteDescription", "path": "HistoAI.Patient.Tumor.Localization.metastasisSiteDescription", "label": "Metastasis Site Description", "short": "Location of the metastasis of this tumor", "definition": "Location/site of the metastasis of this tumor of this patient.", "min": 0, "max": "1", "type": [ { "code": "string", "profile": [ "http://hl7.org/fhir/StructureDefinition/string" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization.regionalRecurrence", "path": "HistoAI.Patient.Tumor.Localization.regionalRecurrence", "label": "Regional Recurrence", "short": "Is this regional recurrence?", "definition": "A regional recurrence denotes tumor involving the ipsilateral regional lymph nodes, usually ipsilateral axillary or supraclavicular, and less commonly infraclavicular and/or internal mammary.", "alias": [ "Eventregionalrecurrence" ], "min": 0, "max": "1", "type": [ { "code": "boolean", "profile": [ "http://hl7.org/fhir/StructureDefinition/boolean" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization.contralateralRecurrence", "path": "HistoAI.Patient.Tumor.Localization.contralateralRecurrence", "label": "Contralateral Recurrence", "short": "Is this metastasis contralateral?", "definition": "Is this metastasis contralateral? Event of contralateral breast cancer (as second primary)", "alias": [ "Contralateral_recurrence" ], "min": 0, "max": "1", "type": [ { "code": "boolean", "profile": [ "http://hl7.org/fhir/StructureDefinition/boolean" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization.localIpsilateralRecurrence", "path": "HistoAI.Patient.Tumor.Localization.localIpsilateralRecurrence", "label": "Local Ipsilateral Recurrence", "short": "Is this local and ipsilateral?", "definition": "Event of local ipsilateral recurrence; Loco-regional Recurrence is defined as a recurrence in the ipsilateral chest wall or mastectomy scar, or ipsilateral supraclavicular, infraclavicular, axillary or internal mammary lymph nodes. LRR must occur after primary diagnosis period and before first distant metastatic diagnosis to be recorded.", "alias": [ "Eventlocalipsilatrecurrence" ], "min": 0, "max": "1", "type": [ { "code": "boolean", "profile": [ "http://hl7.org/fhir/StructureDefinition/boolean" ] } ] }, { "id": "HistoAI.Patient.Tumor.Localization.oligoMetastasis", "path": "HistoAI.Patient.Tumor.Localization.oligoMetastasis", "label": "Oligo Metastasis", "short": "Is this oligo metastasis?", "definition": "Oligo_metastasis (max 3): A type of metastasis in which cancer cells from the original (primary) tumor travel through the body and form a small number of new tumors (metastatic tumors) in one or two other parts of the body.", "min": 0, "max": "1", "type": [ { "code": "boolean", "profile": [ "http://hl7.org/fhir/StructureDefinition/boolean" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment", "path": "HistoAI.Patient.Tumor.Treatment", "label": "Therapy", "short": "Therapy record of this tumor", "definition": "Therapy record of this tumor in tumor registry, TRTH", "alias": [ "Therapie", "Therapy" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.treatmentType", "path": "HistoAI.Patient.Tumor.Treatment.treatmentType", "label": "Treatment Type", "short": "Type of treatment", "definition": "Treatment code (single character):\r\n0 - no treatment\r\n1 - surgery\r\n2 - external radiotherapy\r\n3 - internal radiotherapy or radio-isotopes\r\n4 - chemotherapy\r\n5 - hormonal therapy\r\n6 - immunotherapy\r\n7 - rehabilitation therapy\r\n8 - other therapy\r\n9 - explorative surgery\r\nX - unknown (systemic) treatment", "comment": "Used in TR::TRTU_Behandeling_totaal_code, for example, \"1216\" means: surgery->external radiotherapy->surgery->immunotherapy.\r\nAlso used in TR::TRTH_Behandel_code.", "alias": [ "Treatment code", "Behandel code" ], "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.startDate", "path": "HistoAI.Patient.Tumor.Treatment.startDate", "label": "Start Date", "short": "Start date of the treatment", "definition": "Start date of the treatment or therapy.", "min": 0, "max": "1", "type": [ { "code": "dateTime", "profile": [ "http://hl7.org/fhir/StructureDefinition/dateTime" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.stopDate", "path": "HistoAI.Patient.Tumor.Treatment.stopDate", "label": "Stop Date", "short": "Stop date of the treatment", "definition": "Stop date of the treatment or therapy.", "min": 0, "max": "1", "type": [ { "code": "dateTime", "profile": [ "http://hl7.org/fhir/StructureDefinition/dateTime" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.treatmentIntent", "path": "HistoAI.Patient.Tumor.Treatment.treatmentIntent", "label": "Treatment Intent", "short": "The purpose of this treatment", "definition": "The purpose of this treatment.", "comment": "TODO: find source in DWH", "min": 0, "max": "1", "type": [ { "code": "Narrative", "profile": [ "http://hl7.org/fhir/StructureDefinition/Narrative" ] } ], "mapping": [ { "identity": "TreatmentIntent", "map": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-treatment-intent" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.treatmentSetting", "path": "HistoAI.Patient.Tumor.Treatment.treatmentSetting", "short": "Treatment's purpose in relation to the primary treatment", "definition": "Indicate the treatment setting, which describes the treatment's purpose in relation to the primary treatment. (Reference: CDISC[NCItcode:C124308])", "min": 0, "max": "*", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.terminationReason", "path": "HistoAI.Patient.Tumor.Treatment.terminationReason", "label": "Termination Reason", "short": "Reason of termination with this treatment", "definition": "Reason of termination with this treatment, as indicatior of desease progression.", "comment": "DWH - find out discription of reason of each treatment/therapy stopped at the end date of treatment.\r\nIn the future there will be an extra feature added to Hix in which RECIST measurements (radiological assessment of CT scans)", "min": 0, "max": "1", "type": [ { "code": "Narrative", "profile": [ "http://hl7.org/fhir/StructureDefinition/Narrative" ] } ], "mapping": [ { "identity": "TreatmentTerminationReason", "map": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-treatment-termination-reason" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.treatmentInstituteIndicator", "path": "HistoAI.Patient.Tumor.Treatment.treatmentInstituteIndicator", "label": "Treatment Institute Indicator", "short": "Whether this treatment is primary or secondary", "definition": "Whether this treatment is primary (treated at AvL) or secondary (patient treated at somewhere else).", "comment": "DLC::09.09 Treatment Treatment_PS_ind", "alias": [ "Treatment_PS_ind" ], "min": 0, "max": "1", "type": [ { "code": "boolean", "profile": [ "http://hl7.org/fhir/StructureDefinition/boolean" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Medication", "path": "HistoAI.Patient.Tumor.Treatment.Medication", "label": "Medication", "short": "Medication statement", "definition": "Medication statement", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Medication.medicine", "path": "HistoAI.Patient.Tumor.Treatment.Medication.medicine", "label": "Medicine", "code": [ { "system": "http://hl7.org/fhir/uv/ips/ValueSet/whoatc-uv-ips" } ], "short": "Medicine(s) used in this treatment", "definition": "Medicine(s) used in this treatment.\r\nWorld Health Organization Anatomical Therapeutic Chemical (ATC) classification system. \r\nNote: The currently implemented code system and the value set expansion contain only a set of example ATC codes, not the complete code system content.", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/uv/ips/ValueSet/whoatc-uv-ips" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Medication.numberCourse", "path": "HistoAI.Patient.Tumor.Treatment.Medication.numberCourse", "label": "Number Course", "short": "Number of courses of medication given", "definition": "Number of courses of medication given.", "comment": "DWH::[TR].[TRTH_Aantal_kuren]", "alias": [ "Aantal kuren" ], "min": 0, "max": "1", "type": [ { "code": "integer", "profile": [ "http://hl7.org/fhir/StructureDefinition/integer" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Medication.dosage", "path": "HistoAI.Patient.Tumor.Treatment.Medication.dosage", "label": "Dosage", "short": "General dosage instruction information", "definition": "General dosage instruction information, including site, route, method etc.", "min": 0, "max": "1", "type": [ { "code": "Dosage", "profile": [ "http://hl7.org/fhir/StructureDefinition/Dosage" ] } ], "mapping": [ { "identity": "Dosage", "map": "http://hl7.org/fhir/StructureDefinition/Dosage" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Medication.medicalOutcome", "path": "HistoAI.Patient.Tumor.Treatment.Medication.medicalOutcome", "label": "Medical Outcome", "short": "Medical treatment outcome", "definition": "Medical treatment (chemo or immuno therapy) outcome.", "min": 0, "max": "1", "type": [ { "code": "Narrative", "profile": [ "http://hl7.org/fhir/StructureDefinition/Narrative" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Surgery", "path": "HistoAI.Patient.Tumor.Treatment.Surgery", "label": "Surgery", "short": "Surgical treatment", "definition": "Surgical treatment", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Surgery.procedure", "path": "HistoAI.Patient.Tumor.Treatment.Surgery.procedure", "label": "Procedure", "short": "Surgical procedure code", "definition": "Surgical procedure code", "comment": "TODO: find source of procedure code\r\nTR.TRTH_Therapie_code?", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/code" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Surgery.bodySite", "path": "HistoAI.Patient.Tumor.Treatment.Surgery.bodySite", "label": "Body Site", "short": "Surgery body site", "definition": "Surgery body site ICD-10 code", "comment": "related to Tumor ID (patient and tumorsys), should be the same as primarySite of the tumor (local and regional) or metastasisSite (distant metastasis)", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/sid/icd-10" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Surgery.surgeryOutcome", "path": "HistoAI.Patient.Tumor.Treatment.Surgery.surgeryOutcome", "label": "Surgery Outcome", "short": "Response to surgery outcome", "definition": "Response to surgery outcome", "min": 0, "max": "1", "type": [ { "code": "Narrative", "profile": [ "http://hl7.org/fhir/StructureDefinition/Narrative" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Radiotherapy", "path": "HistoAI.Patient.Tumor.Treatment.Radiotherapy", "label": "Radiotherapy", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-course-summary" } ], "short": "Radiotherapy course summary", "definition": "Radiotherapy course summary", "min": 0, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.modality", "path": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.modality", "label": "Modality", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-modality" } ], "short": "A modality of external beam or brachytherapy radiation procedures", "definition": "A modality of external beam or brachytherapy radiation procedures. e.g. Photons, Electrons", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-modality" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.technique", "path": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.technique", "label": "Technique", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-technique" } ], "short": "A technique of external beam or brachytherapy radiation procedures", "definition": "A technique of external beam or brachytherapy radiation procedures. e.g. VMAT, 3D", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-technique" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.bodySite", "path": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.bodySite", "label": "Body Site", "code": [ { "system": "http://hl7.org/fhir/sid/icd-10" } ], "short": "Anatomical site irradiated", "definition": "Anatomical site irradiated of radiotherapy.", "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/sid/icd-10" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.doseVolume", "path": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.doseVolume", "label": "Dose Volume", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-dose-delivered-to-volume" } ], "short": "Dose parameters for one radiotherapy volume", "definition": "Dose parameters for one radiotherapy volume. e.g.\r\n Prostate, 5000cGy;\r\n SV, 3000 cGy;", "min": 0, "max": "*", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-radiotherapy-dose-delivered-to-volume" ] } ] }, { "id": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.radiologicalOutcome", "path": "HistoAI.Patient.Tumor.Treatment.Radiotherapy.radiologicalOutcome", "label": "Radiological Outcome", "short": "Outcome of radiotherapy", "min": 0, "max": "1", "type": [ { "code": "Narrative", "profile": [ "http://hl7.org/fhir/StructureDefinition/Narrative" ] } ] }, { "id": "HistoAI.Patient.PerformanceStatus", "path": "HistoAI.Patient.PerformanceStatus", "label": "Performance Status", "short": "WHO performace status", "definition": "WHO performance status as recorded on baseline. \r\n0 = Able to carry out all normal activity without restrictions; \r\n1 = Restricted in physically strenuous activity but ambulatory and able to carry out light work; \r\n2 = Ambulatory and capable of all self-care but unable to carry out any work; up and more than 50% of waking hours; \r\n3 = Capable of only limited self-care; confined to bed or chair more than 50% of waking hours; \r\n4 = Completely disabled; cannot carry on any self-care; totally confined to bed or chair.", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.PerformanceStatus.observationDate", "path": "HistoAI.Patient.PerformanceStatus.observationDate", "label": "Observation Date", "short": "Date of the observation of performance status of this patient", "definition": "Date of the observation of performance status of this patient.", "comment": "This is not follow-up date", "min": 0, "max": "1", "type": [ { "code": "dateTime", "profile": [ "http://hl7.org/fhir/StructureDefinition/dateTime" ] } ] }, { "id": "HistoAI.Patient.PerformanceStatus.performanceScore", "path": "HistoAI.Patient.PerformanceStatus.performanceScore", "label": "Performance Score", "code": [ { "system": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-ecog-performance-status" } ], "definition": "WHO performance status as recorded on baseline. \r\n0 = Able to carry out all normal activity without restrictions; \r\n1 = Restricted in physically strenuous activity but ambulatory and able to carry out light work; \r\n2 = Ambulatory and capable of all self-care but unable to carry out any work; up and more than 50% of waking hours; \r\n3 = Capable of only limited self-care; confined to bed or chair more than 50% of waking hours; \r\n4 = Completely disabled; cannot carry on any self-care; totally confined to bed or chair.", "alias": [ "ECOG Performance Status", "Zubrod score", "WHO score" ], "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-ecog-performance-status" ] } ], "mapping": [ { "identity": "ECOGPerformanceStatus", "map": "http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-ecog-performance-status" } ] }, { "id": "HistoAI.Patient.PerformanceStatus.vitalStatus", "path": "HistoAI.Patient.PerformanceStatus.vitalStatus", "label": "Vital Status", "short": "Vital status at this follow-up.", "definition": "Indicator of vital status of follow-up:", "comment": "Death during follow-up can be derived from this.", "alias": [ "disease_status_at_followup" ], "min": 0, "max": "1", "type": [ { "code": "code", "profile": [ "http://hl7.org/fhir/StructureDefinition/vitalsigns" ] } ] }, { "id": "HistoAI.Patient.ClinicalTrial", "path": "HistoAI.Patient.ClinicalTrial", "label": "Clinical Trial", "short": "Clinical trial studies this patient involved in", "definition": "Clinical trial studies this patient involved in. Study ID in clinical trial database Netherlands Cancer Instiute (TRION)", "alias": [ "Study", "Trion" ], "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI.Patient.ClinicalTrial.trionId", "path": "HistoAI.Patient.ClinicalTrial.trionId", "label": "TRION ID", "short": "Unique identifier of clinical trial", "definition": "Unique identifier of clinical trial in database Netherlands Cancer Instiute (TRION), which this patient being involved.", "min": 1, "max": "1", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD", "path": "HistoAI._TBD", "label": "_TBD", "short": "To Be Determined", "definition": "To be determined - data attributes from various sources need to be FHIR compliant", "min": 0, "max": "0", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD.Molpa", "path": "HistoAI._TBD.Molpa", "label": "MolPa", "short": "Molecular Pathology", "definition": "Molecular Pathology record of this patient", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD.Molpa.molpaId", "path": "HistoAI._TBD.Molpa.molpaId", "label": "MOLPA ID", "short": "Unique identifier of MolPa record", "definition": "Unique identifier of MolPa record of this patient.", "min": 1, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] }, { "id": "HistoAI._TBD.Cfmpb", "path": "HistoAI._TBD.Cfmpb", "label": "CFMPB", "short": "CFMPB record of this pationt", "definition": "Core Facility Molecular Pathology & Biobanking records of this patient.\r\n\r\nThe CFMPB registers, evaluates, coordinates, assists and facilitates all kind of research involving human biospecimens (e.g. serum, blood, ctDNA, FFPE and FF biopsies, DNA & RNA). All CFMPB activities are supported by our web application ‘the Application and Request Tool’ ART, an online tool for IRB registration & review and LIMS & database of NKI-AvL.", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD.Cfmpb.cfmpbId", "path": "HistoAI._TBD.Cfmpb.cfmpbId", "label": "CFMPB ID", "short": "Unique identifier of CFMPB record", "definition": "Unique identifier of Core Facility Molecular Pathology & Biobanking.", "min": 1, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] }, { "id": "HistoAI._TBD.Cfmpb.QustionAnswers", "path": "HistoAI._TBD.Cfmpb.QustionAnswers", "label": "Qustion Answers", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD.Cfmpb.QustionAnswers.question", "path": "HistoAI._TBD.Cfmpb.QustionAnswers.question", "label": "CFMPB Question", "short": "The question asked by pathologists", "definition": "The question asked by pathologists", "comment": "TODO: find out the source of [SQRLClin_Test].[CFDB].[ARTCBioPortal].question", "min": 0, "max": "1", "type": [ { "code": "Reference" } ] }, { "id": "HistoAI._TBD.Cfmpb.QustionAnswers.answer", "path": "HistoAI._TBD.Cfmpb.QustionAnswers.answer", "label": "CFMPB Answer", "short": "The answer to the question asked by pathologists", "definition": "The answer to the question asked by pathologists. One question may have multiple answers.", "comment": "TODO: find out the source of [SQRLClin_Test].[CFDB].[ARTCBioPortal].answer", "min": 0, "max": "*", "type": [ { "code": "Reference" } ] }, { "id": "HistoAI._TBD.BloodBiobank", "path": "HistoAI._TBD.BloodBiobank", "label": "Blood BioBank", "short": "Blood biobank record of this patient", "definition": "Blood biobank record of this patient", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD.BloodBiobank.bloodbiobankId", "path": "HistoAI._TBD.BloodBiobank.bloodbiobankId", "label": "Blood Biobank ID", "short": "Unique identifier of the blood biobank record", "definition": "Unique identifier of the blood biobank record.", "min": 1, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] }, { "id": "HistoAI._TBD.GCF", "path": "HistoAI._TBD.GCF", "label": "GCF", "short": "Genomics Core facility", "definition": "The Genomics Core Facility offers Next Generation Sequencing services using Illumina sequencing equipment (NovaSeq6000, HiSeq2500, NextSeq550 and MiSeq).", "min": 0, "max": "*", "type": [ { "code": "BackboneElement" } ] }, { "id": "HistoAI._TBD.GCF.gcfId", "path": "HistoAI._TBD.GCF.gcfId", "label": "GCF ID", "short": "Unique identifier of GCF record of this patient", "definition": "Unique identifier of GCF record of this patient.", "min": 1, "max": "1", "type": [ { "code": "Identifier", "profile": [ "http://hl7.org/fhir/StructureDefinition/Identifier" ] } ] } ] } }