HdBe-MedicationUse2

Profile	Description	Status	URL
HdBe-MedicationUse2	MedicationUse2 is a statement on the historic, current or intended use of a certain medicine.	draft	https://fhir.healthdata.be/StructureDefinition/HdBe-MedicationUse2

MedicationStatement	I		MedicationStatement	Element Id MedicationStatement Short description MedicationUse Alternate names MedicatieGebruik Definition A record of a medication that is being consumed by a patient. A MedicationStatement may indicate that the patient may be taking the medication now or has taken the medication in the past or will be taking the medication in the future. The source of this information can be the patient, significant other (such as a family member or spouse), or a clinician. A common scenario where this information is captured is during the history taking process during a patient visit or stay. The medication information may come from sources such as the patient's memory, from a prescription bottle, or from a list of medications the patient, clinician or other party maintains. The primary difference between a medication statement and a medication administration is that the medication administration has complete administration information and is based on actual administration information from the person who administered the medication. A medication statement is often, if not always, less specific. There is no required date/time when the medication was administered, in fact we only know that a source has reported the patient is taking this medication, where details such as time, quantity, or rate or even medication product may be incomplete or missing or less precise. As stated earlier, the medication statement information may come from the patient's memory, from a prescription bottle or from a list of medications the patient, clinician or other party maintains. Medication administration is more formal and is not missing detailed information. Comments When interpreting a medicationStatement, the value of the status and NotTaken needed to be considered: MedicationStatement.status + MedicationStatement.wasNotTaken Status=Active + NotTaken=T = Not currently taking Status=Completed + NotTaken=T = Not taken in the past Status=Intended + NotTaken=T = No intention of taking Status=Active + NotTaken=F = Taking, but not as prescribed Status=Active + NotTaken=F = Taking Status=Intended +NotTaken= F = Will be taking (not started) Status=Completed + NotTaken=F = Taken in past Status=In Error + NotTaken=N/A = In Error. Data Type MedicationStatement Constraints dom-2:If the resource is contained in another resource, it SHALL NOT contain nested Resources `contained.contained.empty()` dom-4:If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()` dom-3:If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource `contained.where((('#'+id in (%resource.descendants().reference \| %resource.descendants().as(canonical) \| %resource.descendants().as(uri) \| %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()` dom-6:A resource should have narrative for robust management text.`div`.exists() dom-5:If a resource is contained in another resource, it SHALL NOT have a security label `contained.meta.security.empty()` Mappings rim:Entity. Role, or Act workflow:Event rim:SubstanceAdministration zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21338 HdBe-MedicationUse2:MedicationUse
extension	I	0..*	Extension	Element Id MedicationStatement.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension Sliced: Unordered, Open, by url(Value) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
renderedDosageInstruction	I	0..1	Extension(string)	Element Id MedicationStatement.extension:renderedDosageInstruction Short description Optional Extensions Element Alternate names extensions, user content Definition Pre-adopt from FHIR R5 of the `.renderedDosageInstruction` element found in various medication resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(string) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-RenderedDosageInstruction Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:renderedDosageInstruction.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-RenderedDosageInstruction Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.extension:renderedDosageInstruction.value[x] Short description Value of extension Definition The full representation of the dose of the medication included in all dosage instructions. To be used when multiple dosage instructions are included to represent complex dosing such as increasing or tapering doses. Comments The content of the renderedDosageInstructions must not be different than the dose represented in the dosageInstruction content. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A HdBe-InstructionsForUse:InstructionsForUse.Description
valueString			string	There are no (further) constraints on this element Data Type string
prescriber	I	0..1	Extension(pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner))	Element Id MedicationStatement.extension:prescriber Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.Prescriber Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:prescriber.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.Prescriber Mappings rim:N/A
value[x]	I	0..1		Element Id MedicationStatement.extension:prescriber.value[x] Short description Prescriber Alternate names Voorschrijver Definition The health professional that entered the medication agreement with the patient. Comments Each occurrence of the CBB HealthProfessional is normally represented by two FHIR resources: a PractitionerRole resource (instance of HdBe-HealthProfessional-PractitionerRole) and a Practitioner resource (instance of HdBe-HealthProfessional-Practitioner). The Practitioner resource is referenced from the PractitionerRole instance. For this reason, sending systems should fill the reference to the PractitionerRole instance here, and not the Practitioner resource. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:N/A rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23290 HdBe-MedicationUse2:MedicationUse.Prescriber
valueReference			pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)	There are no (further) constraints on this element Data Type pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)
asAgreedIndicator	I	0..1	Extension(boolean)	Element Id MedicationStatement.extension:asAgreedIndicator Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(boolean) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.AsAgreedIndicator Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:asAgreedIndicator.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.AsAgreedIndicator Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.extension:asAgreedIndicator.value[x] Short description AsAgreedIndicator Alternate names VolgensAfspraakIndicator Definition Duration: The intended duration of use. E.g. 5 days or 8 weeks. It is not allowed to indicate the duration in months, because different months have a variable duration in days. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22492 HdBe-MedicationUse2:MedicationUse.AsAgreedIndicator
valueBoolean			boolean	There are no (further) constraints on this element Data Type boolean
modifierExtension	?! I	0..*	Extension	Element Id MedicationStatement.modifierExtension Short description Extensions that cannot be ignored Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself). Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension Sliced: Unordered, Open, by url(Value) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
stopType	?! I	0..1	Extension(CodeableConcept)	Element Id MedicationStatement.modifierExtension:stopType Short description Optional Extensions Element Alternate names extensions, user content Definition This StopType ModifierExtension works differently than the `.status` element of resources because it has a different meaning. The `.status` element represents the status of the resource at the moment of exchanging the resource. This means that over the lifetime of a resource, the status may change (and is very much related to use period). That – in itself – makes mapping StopType (which may never change in an instance) to status not suitable. For example: suppose you want the patient to stop taking medication definitively three days from today. This is a stop medication agreement with a StopType of definitive. However today, tomorrow and the day after tomorrow the `.status` of this medication agreement is active and only after the end date of the usage period the `status` should be stopped. Status and StopType are simply not the same thing. Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(CodeableConcept) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-StopType Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.modifierExtension:stopType.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-StopType Mappings rim:N/A
value[x]		0..1	Binding	Element Id MedicationStatement.modifierExtension:stopType.value[x] Short description MedicationUseStopType Alternate names MedicatieGebruikStopType Definition Stop type, the manner in which this medication is discontinued (temporary or definitive). Comments MedicationAgreementStopType, AdministrationAgreementStopType and MedicationUseStopType all have a bound ValueSet that contain the exact same StopType values. These are represented in the CBB with the same Valueset. This MedicationStopType is used to bind to this extension and reusing this extension for all three concepts. Binding StopType values, based on the valueset named MedicatioStopType, which are applicable for StopType in MedicationAgreement, AdministrationAgreement and MedicationUse. MedicationStopType (required) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23132 HdBe-MedicationUse2:MedicationUse.MedicationUseStopType
valueCodeableConcept			CodeableConcept	There are no (further) constraints on this element Data Type CodeableConcept
repeatPeriodCyclicalSchedule	?! I	0..1	Extension(Duration)	Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(Duration) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.value[x] Short description RepeatPeriodCyclicalSchedule Alternate names HerhaalperiodeCyclischSchema Definition The repeated period in a cyclical schedule (of one or more dosing instructions). A cyclic schedule is noted in days, the corresponding dosing duration is also in days. Examples of a cyclical schedule: contraceptive pill (21 days, 1 pill 1x a day, then skip for 7 days, repeat), repeat period here is 28 days Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-instructionsforuse-v1.2.1-2020EN:NL-CM:9.12.22505 HdBe-InstructionsForUse:InstructionsForUse.RepeatPeriodCyclicalSchedule
valueDuration			Duration	There are no (further) constraints on this element Data Type Duration
identifier	Σ	0..*	Identifier	There are no (further) constraints on this element Element Id MedicationStatement.identifier Short description External identifier Definition Identifiers associated with this Medication Statement that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server. Comments This is a business identifier, not a resource identifier. Data Type Identifier Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CX / EI (occasionally, more often EI maps to a resource id or a URL) rim:II - The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs. Also maps to Role[classCode=IDENT] servd:Identifier workflow:Event.identifier w5:FiveWs.identifier rim:.id
basedOn	Σ I	0..*	Reference(MedicationRequest \| CarePlan \| ServiceRequest)	There are no (further) constraints on this element Element Id MedicationStatement.basedOn Short description Fulfils plan, proposal or order Definition A plan, proposal or order that is fulfilled in whole or in part by this event. Requirements Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(MedicationRequest \| CarePlan \| ServiceRequest) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.basedOn rim:.outboundRelationship[typeCode=FLFS].target[classCode=SBADM or PROC or PCPR or OBS, moodCode=RQO orPLAN or PRP]
partOf	Σ I	0..*	Reference(MedicationAdministration \| MedicationDispense \| MedicationStatement \| Procedure \| Observation)	There are no (further) constraints on this element Element Id MedicationStatement.partOf Short description Part of referenced event Definition A larger event of which this particular event is a component or step. Requirements This should not be used when indicating which resource a MedicationStatement has been derived from. If that is the use case, then MedicationStatement.derivedFrom should be used. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(MedicationAdministration \| MedicationDispense \| MedicationStatement \| Procedure \| Observation) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.partOf rim:.outboundRelationship[typeCode=COMP]/target[classCode=SPLY or SBADM or PROC or OBS,moodCode=EVN]
status	Σ ?!	1..1	codeBinding	Element Id MedicationStatement.status Short description UseIndicator / MedicationUseStopType / PeriodOfUse Alternate names MedicatieGebruikStopType, GebruikIndicator, Gebruiksperiode Definition Status may contain information on the stop type, the manner in which this medication is discontinued (temporary or definitive) and if the medicine is used or not. Comments This element is mapped to the CBB concept UseIndicator and implicitly to MedicationUseStopType and PeriodOfUse. Unless a more appropriate status is recorded, the following guidance applies: When MedicationUseStopType has no value and UseIndicator is true, `.status` will usually be set to active. When UseIndicator is false, `.status` will be set to not-taken. When MedicationUseStopType is 14803004, `.status` will usually be set to on-hold. When MedicationUseStopType is 255545003, `.status` will usually be set to stopped. When PeriodOfUse start date is in the past and PeriodOfUse end date is present and in the future, `.status` will usually be set to active. When PeriodOfUse end date has a value and in the past, `.status` will usually be set to completed. When PeriodOfUse duration and start date are known, the end date can be deducted and the previous rules apply. When a system is unable to infer the status, `.status` will be set to unknown. The unknown code is not to be used to convey other statuses. The unknown code should be used when one of the statuses applies, but the authoring system doesn't know the current state of the MedicationStatement. Data Type code Binding Use ConceptMap 'MedicationStopType-to-MedicationStatementStatus' to translate CBB terminology to profile terminology in ValueSet 'Medication Status Codes'. Medication Status Codes (required) Permitted Values MedicationStopType_to_MedicationStatementStatus Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.status w5:FiveWs.status rim:.statusCode zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22399 zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23132 zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22663 HdBe-MedicationUse2:MedicationUse.UseIndicator HdBe-MedicationUse2:MedicationUse.MedicationUseStopType HdBe-MedicationUse2:MedicationUse.PeriodOfUse
statusReason		0..*	CodeableConceptBinding	Element Id MedicationStatement.statusReason Short description ReasonForChangeOrDiscontinuationOfUse Alternate names RedenWijzigenOfStoppenGebruik Definition Reason for changing or discontinuing use of medication. Comments This is generally only used for "exception" statuses such as "not-taken", "on-hold", "cancelled" or "entered-in-error". The reason for performing the event at all is captured in reasonCode, not here. Data Type CodeableConcept Binding A coded concept indicating the reason for the status of the statement. MedicationReason (required) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.statusReason rim:.inboundRelationship[typeCode=SUBJ].source[classCode=CACT, moodCode=EVN].reasonCOde zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22493 HdBe-MedicationUse2:MedicationUse.ReasonForChangeOrDiscontinuationOfUse
category	Σ	1..1	CodeableConceptBinding	Element Id MedicationStatement.category Short description Type of medication usage Definition Indicates where the medication is expected to be consumed or administered. Comments Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination. Data Type CodeableConcept Binding A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered. Medication usage category codes (preferred) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Pattern { "coding": [ { "system": "http://snomed.info/sct", "code": "422979000" } ] } Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD w5:FiveWs.class rim:.inboundRelationship[typeCode=COMP].source[classCode=OBS, moodCode=EVN, code="type of medication usage"].value
medication[x]	Σ	1..1		Element Id MedicationStatement.medication[x] Short description What medication was taken Definition Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications. Comments If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource. Sliced: Unordered, Open, by $this(Type) Binding A coded concept identifying the substance or product being taken. SNOMEDCTMedicationCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.code w5:FiveWs.what[x] rim:.participation[typeCode=CSM].role[classCode=ADMM or MANU]
medicationCodeableConcept			CodeableConcept	There are no (further) constraints on this element Data Type CodeableConcept
medicationReference	Σ	0..1	Reference(Medication \| HdBe PharmaceuticalProduct)	Element Id MedicationStatement.medication[x]:medicationReference Short description ProductUsed Alternate names Gebruiksproduct Definition The product used. This is usually medication. Food, blood products, aids and bandages do not strictly fall under the category of medication, but can be recorded as well. In principle, this will be the prescribed product, but the product used may differ from the prescribed product. Comments If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource. Data Type Reference(Medication \| HdBe PharmaceuticalProduct) Binding A coded concept identifying the substance or product being taken. SNOMEDCTMedicationCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.code w5:FiveWs.what[x] rim:.participation[typeCode=CSM].role[classCode=ADMM or MANU] zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21339 HdBe-MedicationUse2:MedicationUse.ProductUsed
subject	Σ I	1..1	Reference(Group \| HdBe Patient)	Element Id MedicationStatement.subject Short description Who is/was taking the medication Definition The person, animal or group who is/was taking the medication. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Group \| HdBe Patient) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.subject w5:FiveWs.subject[x] v2:PID-3-Patient ID List rim:.participation[typeCode=SBJ].role[classCode=PAT] w5:FiveWs.subject
context	Σ I	0..1	Reference(Encounter \| EpisodeOfCare)	There are no (further) constraints on this element Element Id MedicationStatement.context Short description Encounter / Episode associated with MedicationStatement Definition The encounter or episode of care that establishes the context for this MedicationStatement. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Encounter \| EpisodeOfCare) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.context rim:.inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN, code="type of encounter or episode"]
effective[x]	Σ	0..1		Element Id MedicationStatement.effective[x] Short description The date/time or interval when the medication is/was/will be taken Definition The interval of time during which it is being asserted that the patient is/was/will be taking the medication (or was not taking, when the MedicationStatement.taken element is No). Comments This attribute reflects the period over which the patient consumed the medication and is expected to be populated on the majority of Medication Statements. If the medication is still being taken at the time the statement is recorded, the "end" date will be omitted. The date/time attribute supports a variety of dates - year, year/month and exact date. If something more than this is required, this should be conveyed as text. Sliced: Unordered, Open, by $this(Type) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.occurrence[x] w5:FiveWs.done[x] rim:.effectiveTime
effectiveDateTime			dateTime	There are no (further) constraints on this element Data Type dateTime
effectivePeriod	Σ I	0..1	HdBe TimeInterval	Element Id MedicationStatement.effective[x]:effectivePeriod Short description PeriodOfUse Alternate names Gebruiksperiode Definition Medication use can be recorded for a certain moment or over a certain period. Thus, medication use can be recorded multiple times during the use of medication. The usage period is the period or moment over which the data is recorded. Start date: This is the time at which the agreement was to take effect (or took effect or will take effect). End date: The time at which the period of use ends (or ended or will end). To avoid confusion between 'to' and 'up to', the submission of time is always mandatory for the end date. Comments A Period specifies a range of time; the context of use will specify whether the entire range applies (e.g. "the patient was an inpatient of the hospital for this time range") or one value from the range applies (e.g. "give to the patient between these two times"). Period is not used for a duration (a measure of elapsed time). See Duration. Data Type HdBe TimeInterval Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` per-1:If present, start SHALL have a lower value than end `start.hasValue().not() or end.hasValue().not() or (start <= end)` Mappings rim:n/a workflow:Event.occurrence[x] w5:FiveWs.done[x] rim:.effectiveTime v2:DR rim:IVL<TS>[lowClosed="true" and highClosed="true"] or URG<TS>[lowClosed="true" and highClosed="true"] HdBe-TimeInterval:TimeInterval zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22663 HdBe-MedicationUse2:MedicationUse.PeriodOfUse
dateAsserted	Σ	0..1	dateTime	Element Id MedicationStatement.dateAsserted Short description MedicationUseDateTime Alternate names MedicatieGebruikDatumTijd Definition Date on which this use is entered. Data Type dateTime Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a w5:FiveWs.recorded rim:.participation[typeCode=AUT].time zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22398 HdBe-MedicationUse2:MedicationUse.MedicationUseDateTime
informationSource	I	0..1	Reference(Patient \| Practitioner \| PractitionerRole \| RelatedPerson \| Organization)	There are no (further) constraints on this element Element Id MedicationStatement.informationSource Short description Person or organization that provided the information about the taking of this medication Definition The person or organization that provided the information about the taking of this medication. Note: Use derivedFrom when a MedicationStatement is derived from other resources, e.g. Claim or MedicationRequest. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Patient \| Practitioner \| PractitionerRole \| RelatedPerson \| Organization) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) w5:FiveWs.source rim:.participation[typeCode=INF].role[classCode=PAT, or codes for Practioner or Related Person (if PAT is the informer, then syntax for self-reported =true)
derivedFrom	I	0..*	Reference(Resource)	There are no (further) constraints on this element Element Id MedicationStatement.derivedFrom Short description Additional supporting information Definition Allows linking the MedicationStatement to the underlying MedicationRequest, or to other information that supports or is used to derive the MedicationStatement. Comments Likely references would be to MedicationRequest, MedicationDispense, Claim, Observation or QuestionnaireAnswers. The most common use cases for deriving a MedicationStatement comes from creating a MedicationStatement from a MedicationRequest or from a lab observation or a claim. it should be noted that the amount of information that is available varies from the type resource that you derive the MedicationStatement from. Data Type Reference(Resource) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) rim:.outboundRelationship[typeCode=SPRT]/target[classCode=ACT,moodCode=EVN]
reasonCode		0..*	CodeableConcept	Element Id MedicationStatement.reasonCode Short description Reason for why the medication is being/was taken Definition A reason for why the medication is being/was taken. Comments This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference. Data Type CodeableConcept Sliced: Unordered, Open, by text(Exists) Binding A coded concept identifying why the medication is being taken. Condition/Problem/DiagnosisCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.reasonCode w5:FiveWs.why[x] rim:.reasonCode
reasonForUse		0..1	CodeableConcept	There are no (further) constraints on this element Element Id MedicationStatement.reasonCode:reasonForUse Short description Reason for why the medication is being/was taken Definition A reason for why the medication is being/was taken. Comments This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference. Data Type CodeableConcept Binding A coded concept identifying why the medication is being taken. Condition/Problem/DiagnosisCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.reasonCode w5:FiveWs.why[x] rim:.reasonCode
coding	Σ	0..*	Coding	There are no (further) constraints on this element Element Id MedicationStatement.reasonCode:reasonForUse.coding Short description Code defined by a terminology system Definition A reference to a code defined by a terminology system. Requirements Allows for alternative encodings within a code system, and translations to other code systems. Comments Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true. Data Type Coding Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE subset one of the sets of component 1-3 or 4-6 rim:CV orim:fhir:Coding rdfs:subClassOf dt:CDCoding v2:CE.1-8, CE.10-22 rim:union(., ./translation) orim:fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding
text	Σ	1..1	string	Element Id MedicationStatement.reasonCode:reasonForUse.text Short description ReasonForUse Alternate names RedenGebruik Definition The reason for using the medication, particularly in self-care medicine purchased by the patient themselves. Requirements The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source. Comments Very often the text is the same as a displayName of one of the codings. Data Type string Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE.9. But note many systems use CE.2 for this rim:./originalText[mediaType/code="text/plain"]/data orim:fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22491 HdBe-MedicationUse2:MedicationUse.ReasonForUse
reasonReference	I	0..*	Reference(Condition \| Observation \| DiagnosticReport)	There are no (further) constraints on this element Element Id MedicationStatement.reasonReference Short description Condition or observation that supports why the medication is being/was taken Definition Condition or observation that supports why the medication is being/was taken. Comments This is a reference to a condition that is the reason why the medication is being/was taken. If only a code exists, use reasonForUseCode. Data Type Reference(Condition \| Observation \| DiagnosticReport) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.reasonReference w5:FiveWs.why[x] rim:.outboundRelationship[typeCode=RSON]/target[classCode=OBS,moodCode=EVN, code="reason for use"].value
note		0..1	Annotation	There are no (further) constraints on this element Element Id MedicationStatement.note Short description Further information about the statement Definition Provides extra information about the medication statement that is not conveyed by the other attributes. Comments For systems that do not have structured annotations, they can simply communicate a single annotation with no author or time. This element may need to be included in narrative because of the potential for modifying information. Annotations SHOULD NOT be used to communicate "modifying" information that could be computable. (This is a SHOULD because enforcing user behavior is nearly impossible). Data Type Annotation Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act workflow:Event.note rim:.inboundRelationship[typeCode=SUBJ]/source[classCode=OBS,moodCode=EVN,code="annotation"].value
author[x]	Σ	0..1		There are no (further) constraints on this element Element Id MedicationStatement.note.author[x] Short description Individual responsible for the annotation Definition The individual responsible for making the annotation. Comments Organization is used when there's no need for specific attribution as to who made the comment. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.participant[typeCode=AUT].role
authorString			string	There are no (further) constraints on this element Data Type string
authorReference			Reference(Practitioner \| Patient \| RelatedPerson \| Organization)	There are no (further) constraints on this element Data Type Reference(Practitioner \| Patient \| RelatedPerson \| Organization)
time	Σ	0..1	dateTime	There are no (further) constraints on this element Element Id MedicationStatement.note.time Short description When the annotation was made Definition Indicates when this particular annotation was made. Data Type dateTime Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.effectiveTime
text	Σ	1..1	markdown	Element Id MedicationStatement.note.text Short description Comment Alternate names Toelichting Definition Comments on the medication use. Comments Systems are not required to have markdown support, so the text should be readable without markdown processing. The markdown syntax is GFM - see https://github.github.com/gfm/ Data Type markdown Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.text zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21624 HdBe-MedicationUse2:MedicationUse.Comment
dosage		0..*	HdBe InstructionsForUse.DosageInstructions	Element Id MedicationStatement.dosage Short description DosingInstructions / InstructionsForUse Alternate names Doseerinstructie, Gebruiksinstructie Definition Instructions for the use of the medication, e.g. dose and route of administration. In the event of medication use, this is the pattern of use established by the patient or which the patient followed. Comments This element mostly represents the DosingInstructions container from CBB InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are duplicated in every repetition of this element, even though these concepts should be present just once according to the CBB. The RepeatPeriodCyclicalSchedule and Description elements of the CBB are not represented in this profile. When a HdBe profile contains a InstructionsForUse.DosageInstructions datatype, the RepeatPeriodCyclicalSchedule and Description elements are separately added to this profile as well. This element does not contain a mapping to the Dosage container from CBB InstructionsForUse. However, the child concepts of Dosage are all mapped. Multiple Dosage instances are represented by another DosingInstructions that contains a similiar SequenceNumber. Data Type HdBe InstructionsForUse.DosageInstructions Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:.outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT] rim:refer dosageInstruction mapping zib-instructionsforuse-v1.2.1-2020EN:NL-CM:9.12.22095 HdBe-InstructionsForUse:InstructionsForUse.DosingInstructions zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22504 HdBe-MedicationUse2:MedicationUse.InstructionsForUse

MedicationStatement	I		MedicationStatement	Element Id MedicationStatement Short description MedicationUse Alternate names MedicatieGebruik Definition A record of a medication that is being consumed by a patient. A MedicationStatement may indicate that the patient may be taking the medication now or has taken the medication in the past or will be taking the medication in the future. The source of this information can be the patient, significant other (such as a family member or spouse), or a clinician. A common scenario where this information is captured is during the history taking process during a patient visit or stay. The medication information may come from sources such as the patient's memory, from a prescription bottle, or from a list of medications the patient, clinician or other party maintains. The primary difference between a medication statement and a medication administration is that the medication administration has complete administration information and is based on actual administration information from the person who administered the medication. A medication statement is often, if not always, less specific. There is no required date/time when the medication was administered, in fact we only know that a source has reported the patient is taking this medication, where details such as time, quantity, or rate or even medication product may be incomplete or missing or less precise. As stated earlier, the medication statement information may come from the patient's memory, from a prescription bottle or from a list of medications the patient, clinician or other party maintains. Medication administration is more formal and is not missing detailed information. Comments When interpreting a medicationStatement, the value of the status and NotTaken needed to be considered: MedicationStatement.status + MedicationStatement.wasNotTaken Status=Active + NotTaken=T = Not currently taking Status=Completed + NotTaken=T = Not taken in the past Status=Intended + NotTaken=T = No intention of taking Status=Active + NotTaken=F = Taking, but not as prescribed Status=Active + NotTaken=F = Taking Status=Intended +NotTaken= F = Will be taking (not started) Status=Completed + NotTaken=F = Taken in past Status=In Error + NotTaken=N/A = In Error. Data Type MedicationStatement Constraints dom-2:If the resource is contained in another resource, it SHALL NOT contain nested Resources `contained.contained.empty()` dom-4:If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()` dom-3:If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource `contained.where((('#'+id in (%resource.descendants().reference \| %resource.descendants().as(canonical) \| %resource.descendants().as(uri) \| %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()` dom-6:A resource should have narrative for robust management text.`div`.exists() dom-5:If a resource is contained in another resource, it SHALL NOT have a security label `contained.meta.security.empty()` Mappings rim:Entity. Role, or Act workflow:Event rim:SubstanceAdministration zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21338 HdBe-MedicationUse2:MedicationUse
extension	I	0..*	Extension	Element Id MedicationStatement.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension Sliced: Unordered, Open, by url(Value) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
renderedDosageInstruction	I	0..1	Extension(string)	Element Id MedicationStatement.extension:renderedDosageInstruction Short description Optional Extensions Element Alternate names extensions, user content Definition Pre-adopt from FHIR R5 of the `.renderedDosageInstruction` element found in various medication resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(string) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-RenderedDosageInstruction Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:renderedDosageInstruction.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-RenderedDosageInstruction Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.extension:renderedDosageInstruction.value[x] Short description Value of extension Definition The full representation of the dose of the medication included in all dosage instructions. To be used when multiple dosage instructions are included to represent complex dosing such as increasing or tapering doses. Comments The content of the renderedDosageInstructions must not be different than the dose represented in the dosageInstruction content. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A HdBe-InstructionsForUse:InstructionsForUse.Description
valueString			string	There are no (further) constraints on this element Data Type string
prescriber	I	0..1	Extension(pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner))	Element Id MedicationStatement.extension:prescriber Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.Prescriber Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:prescriber.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.Prescriber Mappings rim:N/A
value[x]	I	0..1		Element Id MedicationStatement.extension:prescriber.value[x] Short description Prescriber Alternate names Voorschrijver Definition The health professional that entered the medication agreement with the patient. Comments Each occurrence of the CBB HealthProfessional is normally represented by two FHIR resources: a PractitionerRole resource (instance of HdBe-HealthProfessional-PractitionerRole) and a Practitioner resource (instance of HdBe-HealthProfessional-Practitioner). The Practitioner resource is referenced from the PractitionerRole instance. For this reason, sending systems should fill the reference to the PractitionerRole instance here, and not the Practitioner resource. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:N/A rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23290 HdBe-MedicationUse2:MedicationUse.Prescriber
valueReference			pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)	There are no (further) constraints on this element Data Type pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)
asAgreedIndicator	I	0..1	Extension(boolean)	Element Id MedicationStatement.extension:asAgreedIndicator Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(boolean) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.AsAgreedIndicator Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:asAgreedIndicator.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.AsAgreedIndicator Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.extension:asAgreedIndicator.value[x] Short description AsAgreedIndicator Alternate names VolgensAfspraakIndicator Definition Duration: The intended duration of use. E.g. 5 days or 8 weeks. It is not allowed to indicate the duration in months, because different months have a variable duration in days. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22492 HdBe-MedicationUse2:MedicationUse.AsAgreedIndicator
valueBoolean			boolean	There are no (further) constraints on this element Data Type boolean
modifierExtension	?! I	0..*	Extension	Element Id MedicationStatement.modifierExtension Short description Extensions that cannot be ignored Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself). Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension Sliced: Unordered, Open, by url(Value) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
stopType	?! I	0..1	Extension(CodeableConcept)	Element Id MedicationStatement.modifierExtension:stopType Short description Optional Extensions Element Alternate names extensions, user content Definition This StopType ModifierExtension works differently than the `.status` element of resources because it has a different meaning. The `.status` element represents the status of the resource at the moment of exchanging the resource. This means that over the lifetime of a resource, the status may change (and is very much related to use period). That – in itself – makes mapping StopType (which may never change in an instance) to status not suitable. For example: suppose you want the patient to stop taking medication definitively three days from today. This is a stop medication agreement with a StopType of definitive. However today, tomorrow and the day after tomorrow the `.status` of this medication agreement is active and only after the end date of the usage period the `status` should be stopped. Status and StopType are simply not the same thing. Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(CodeableConcept) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-StopType Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.modifierExtension:stopType.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-StopType Mappings rim:N/A
value[x]		0..1	Binding	Element Id MedicationStatement.modifierExtension:stopType.value[x] Short description MedicationUseStopType Alternate names MedicatieGebruikStopType Definition Stop type, the manner in which this medication is discontinued (temporary or definitive). Comments MedicationAgreementStopType, AdministrationAgreementStopType and MedicationUseStopType all have a bound ValueSet that contain the exact same StopType values. These are represented in the CBB with the same Valueset. This MedicationStopType is used to bind to this extension and reusing this extension for all three concepts. Binding StopType values, based on the valueset named MedicatioStopType, which are applicable for StopType in MedicationAgreement, AdministrationAgreement and MedicationUse. MedicationStopType (required) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23132 HdBe-MedicationUse2:MedicationUse.MedicationUseStopType
valueCodeableConcept			CodeableConcept	There are no (further) constraints on this element Data Type CodeableConcept
repeatPeriodCyclicalSchedule	?! I	0..1	Extension(Duration)	Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(Duration) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.value[x] Short description RepeatPeriodCyclicalSchedule Alternate names HerhaalperiodeCyclischSchema Definition The repeated period in a cyclical schedule (of one or more dosing instructions). A cyclic schedule is noted in days, the corresponding dosing duration is also in days. Examples of a cyclical schedule: contraceptive pill (21 days, 1 pill 1x a day, then skip for 7 days, repeat), repeat period here is 28 days Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-instructionsforuse-v1.2.1-2020EN:NL-CM:9.12.22505 HdBe-InstructionsForUse:InstructionsForUse.RepeatPeriodCyclicalSchedule
valueDuration			Duration	There are no (further) constraints on this element Data Type Duration
identifier	Σ	0..*	Identifier	There are no (further) constraints on this element Element Id MedicationStatement.identifier Short description External identifier Definition Identifiers associated with this Medication Statement that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server. Comments This is a business identifier, not a resource identifier. Data Type Identifier Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CX / EI (occasionally, more often EI maps to a resource id or a URL) rim:II - The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs. Also maps to Role[classCode=IDENT] servd:Identifier workflow:Event.identifier w5:FiveWs.identifier rim:.id
basedOn	Σ I	0..*	Reference(MedicationRequest \| CarePlan \| ServiceRequest)	There are no (further) constraints on this element Element Id MedicationStatement.basedOn Short description Fulfils plan, proposal or order Definition A plan, proposal or order that is fulfilled in whole or in part by this event. Requirements Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(MedicationRequest \| CarePlan \| ServiceRequest) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.basedOn rim:.outboundRelationship[typeCode=FLFS].target[classCode=SBADM or PROC or PCPR or OBS, moodCode=RQO orPLAN or PRP]
partOf	Σ I	0..*	Reference(MedicationAdministration \| MedicationDispense \| MedicationStatement \| Procedure \| Observation)	There are no (further) constraints on this element Element Id MedicationStatement.partOf Short description Part of referenced event Definition A larger event of which this particular event is a component or step. Requirements This should not be used when indicating which resource a MedicationStatement has been derived from. If that is the use case, then MedicationStatement.derivedFrom should be used. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(MedicationAdministration \| MedicationDispense \| MedicationStatement \| Procedure \| Observation) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.partOf rim:.outboundRelationship[typeCode=COMP]/target[classCode=SPLY or SBADM or PROC or OBS,moodCode=EVN]
status	Σ ?!	1..1	codeBinding	Element Id MedicationStatement.status Short description UseIndicator / MedicationUseStopType / PeriodOfUse Alternate names MedicatieGebruikStopType, GebruikIndicator, Gebruiksperiode Definition Status may contain information on the stop type, the manner in which this medication is discontinued (temporary or definitive) and if the medicine is used or not. Comments This element is mapped to the CBB concept UseIndicator and implicitly to MedicationUseStopType and PeriodOfUse. Unless a more appropriate status is recorded, the following guidance applies: When MedicationUseStopType has no value and UseIndicator is true, `.status` will usually be set to active. When UseIndicator is false, `.status` will be set to not-taken. When MedicationUseStopType is 14803004, `.status` will usually be set to on-hold. When MedicationUseStopType is 255545003, `.status` will usually be set to stopped. When PeriodOfUse start date is in the past and PeriodOfUse end date is present and in the future, `.status` will usually be set to active. When PeriodOfUse end date has a value and in the past, `.status` will usually be set to completed. When PeriodOfUse duration and start date are known, the end date can be deducted and the previous rules apply. When a system is unable to infer the status, `.status` will be set to unknown. The unknown code is not to be used to convey other statuses. The unknown code should be used when one of the statuses applies, but the authoring system doesn't know the current state of the MedicationStatement. Data Type code Binding Use ConceptMap 'MedicationStopType-to-MedicationStatementStatus' to translate CBB terminology to profile terminology in ValueSet 'Medication Status Codes'. Medication Status Codes (required) Permitted Values MedicationStopType_to_MedicationStatementStatus Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.status w5:FiveWs.status rim:.statusCode zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22399 zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23132 zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22663 HdBe-MedicationUse2:MedicationUse.UseIndicator HdBe-MedicationUse2:MedicationUse.MedicationUseStopType HdBe-MedicationUse2:MedicationUse.PeriodOfUse
statusReason		0..*	CodeableConceptBinding	Element Id MedicationStatement.statusReason Short description ReasonForChangeOrDiscontinuationOfUse Alternate names RedenWijzigenOfStoppenGebruik Definition Reason for changing or discontinuing use of medication. Comments This is generally only used for "exception" statuses such as "not-taken", "on-hold", "cancelled" or "entered-in-error". The reason for performing the event at all is captured in reasonCode, not here. Data Type CodeableConcept Binding A coded concept indicating the reason for the status of the statement. MedicationReason (required) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.statusReason rim:.inboundRelationship[typeCode=SUBJ].source[classCode=CACT, moodCode=EVN].reasonCOde zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22493 HdBe-MedicationUse2:MedicationUse.ReasonForChangeOrDiscontinuationOfUse
category	Σ	1..1	CodeableConceptBinding	Element Id MedicationStatement.category Short description Type of medication usage Definition Indicates where the medication is expected to be consumed or administered. Comments Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination. Data Type CodeableConcept Binding A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered. Medication usage category codes (preferred) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Pattern { "coding": [ { "system": "http://snomed.info/sct", "code": "422979000" } ] } Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD w5:FiveWs.class rim:.inboundRelationship[typeCode=COMP].source[classCode=OBS, moodCode=EVN, code="type of medication usage"].value
medication[x]	Σ	1..1		Element Id MedicationStatement.medication[x] Short description What medication was taken Definition Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications. Comments If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource. Sliced: Unordered, Open, by $this(Type) Binding A coded concept identifying the substance or product being taken. SNOMEDCTMedicationCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.code w5:FiveWs.what[x] rim:.participation[typeCode=CSM].role[classCode=ADMM or MANU]
medicationCodeableConcept			CodeableConcept	There are no (further) constraints on this element Data Type CodeableConcept
medicationReference	Σ	0..1	Reference(Medication \| HdBe PharmaceuticalProduct)	Element Id MedicationStatement.medication[x]:medicationReference Short description ProductUsed Alternate names Gebruiksproduct Definition The product used. This is usually medication. Food, blood products, aids and bandages do not strictly fall under the category of medication, but can be recorded as well. In principle, this will be the prescribed product, but the product used may differ from the prescribed product. Comments If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource. Data Type Reference(Medication \| HdBe PharmaceuticalProduct) Binding A coded concept identifying the substance or product being taken. SNOMEDCTMedicationCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.code w5:FiveWs.what[x] rim:.participation[typeCode=CSM].role[classCode=ADMM or MANU] zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21339 HdBe-MedicationUse2:MedicationUse.ProductUsed
subject	Σ I	1..1	Reference(Group \| HdBe Patient)	Element Id MedicationStatement.subject Short description Who is/was taking the medication Definition The person, animal or group who is/was taking the medication. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Group \| HdBe Patient) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.subject w5:FiveWs.subject[x] v2:PID-3-Patient ID List rim:.participation[typeCode=SBJ].role[classCode=PAT] w5:FiveWs.subject
context	Σ I	0..1	Reference(Encounter \| EpisodeOfCare)	There are no (further) constraints on this element Element Id MedicationStatement.context Short description Encounter / Episode associated with MedicationStatement Definition The encounter or episode of care that establishes the context for this MedicationStatement. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Encounter \| EpisodeOfCare) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.context rim:.inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN, code="type of encounter or episode"]
effective[x]	Σ	0..1		Element Id MedicationStatement.effective[x] Short description The date/time or interval when the medication is/was/will be taken Definition The interval of time during which it is being asserted that the patient is/was/will be taking the medication (or was not taking, when the MedicationStatement.taken element is No). Comments This attribute reflects the period over which the patient consumed the medication and is expected to be populated on the majority of Medication Statements. If the medication is still being taken at the time the statement is recorded, the "end" date will be omitted. The date/time attribute supports a variety of dates - year, year/month and exact date. If something more than this is required, this should be conveyed as text. Sliced: Unordered, Open, by $this(Type) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.occurrence[x] w5:FiveWs.done[x] rim:.effectiveTime
effectiveDateTime			dateTime	There are no (further) constraints on this element Data Type dateTime
effectivePeriod	Σ I	0..1	HdBe TimeInterval	Element Id MedicationStatement.effective[x]:effectivePeriod Short description PeriodOfUse Alternate names Gebruiksperiode Definition Medication use can be recorded for a certain moment or over a certain period. Thus, medication use can be recorded multiple times during the use of medication. The usage period is the period or moment over which the data is recorded. Start date: This is the time at which the agreement was to take effect (or took effect or will take effect). End date: The time at which the period of use ends (or ended or will end). To avoid confusion between 'to' and 'up to', the submission of time is always mandatory for the end date. Comments A Period specifies a range of time; the context of use will specify whether the entire range applies (e.g. "the patient was an inpatient of the hospital for this time range") or one value from the range applies (e.g. "give to the patient between these two times"). Period is not used for a duration (a measure of elapsed time). See Duration. Data Type HdBe TimeInterval Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` per-1:If present, start SHALL have a lower value than end `start.hasValue().not() or end.hasValue().not() or (start <= end)` Mappings rim:n/a workflow:Event.occurrence[x] w5:FiveWs.done[x] rim:.effectiveTime v2:DR rim:IVL<TS>[lowClosed="true" and highClosed="true"] or URG<TS>[lowClosed="true" and highClosed="true"] HdBe-TimeInterval:TimeInterval zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22663 HdBe-MedicationUse2:MedicationUse.PeriodOfUse
dateAsserted	Σ	0..1	dateTime	Element Id MedicationStatement.dateAsserted Short description MedicationUseDateTime Alternate names MedicatieGebruikDatumTijd Definition Date on which this use is entered. Data Type dateTime Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a w5:FiveWs.recorded rim:.participation[typeCode=AUT].time zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22398 HdBe-MedicationUse2:MedicationUse.MedicationUseDateTime
informationSource	I	0..1	Reference(Patient \| Practitioner \| PractitionerRole \| RelatedPerson \| Organization)	There are no (further) constraints on this element Element Id MedicationStatement.informationSource Short description Person or organization that provided the information about the taking of this medication Definition The person or organization that provided the information about the taking of this medication. Note: Use derivedFrom when a MedicationStatement is derived from other resources, e.g. Claim or MedicationRequest. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Patient \| Practitioner \| PractitionerRole \| RelatedPerson \| Organization) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) w5:FiveWs.source rim:.participation[typeCode=INF].role[classCode=PAT, or codes for Practioner or Related Person (if PAT is the informer, then syntax for self-reported =true)
derivedFrom	I	0..*	Reference(Resource)	There are no (further) constraints on this element Element Id MedicationStatement.derivedFrom Short description Additional supporting information Definition Allows linking the MedicationStatement to the underlying MedicationRequest, or to other information that supports or is used to derive the MedicationStatement. Comments Likely references would be to MedicationRequest, MedicationDispense, Claim, Observation or QuestionnaireAnswers. The most common use cases for deriving a MedicationStatement comes from creating a MedicationStatement from a MedicationRequest or from a lab observation or a claim. it should be noted that the amount of information that is available varies from the type resource that you derive the MedicationStatement from. Data Type Reference(Resource) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) rim:.outboundRelationship[typeCode=SPRT]/target[classCode=ACT,moodCode=EVN]
reasonCode		0..*	CodeableConcept	Element Id MedicationStatement.reasonCode Short description Reason for why the medication is being/was taken Definition A reason for why the medication is being/was taken. Comments This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference. Data Type CodeableConcept Sliced: Unordered, Open, by text(Exists) Binding A coded concept identifying why the medication is being taken. Condition/Problem/DiagnosisCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.reasonCode w5:FiveWs.why[x] rim:.reasonCode
reasonForUse		0..1	CodeableConcept	There are no (further) constraints on this element Element Id MedicationStatement.reasonCode:reasonForUse Short description Reason for why the medication is being/was taken Definition A reason for why the medication is being/was taken. Comments This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference. Data Type CodeableConcept Binding A coded concept identifying why the medication is being taken. Condition/Problem/DiagnosisCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.reasonCode w5:FiveWs.why[x] rim:.reasonCode
coding	Σ	0..*	Coding	There are no (further) constraints on this element Element Id MedicationStatement.reasonCode:reasonForUse.coding Short description Code defined by a terminology system Definition A reference to a code defined by a terminology system. Requirements Allows for alternative encodings within a code system, and translations to other code systems. Comments Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true. Data Type Coding Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE subset one of the sets of component 1-3 or 4-6 rim:CV orim:fhir:Coding rdfs:subClassOf dt:CDCoding v2:CE.1-8, CE.10-22 rim:union(., ./translation) orim:fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding
text	Σ	1..1	string	Element Id MedicationStatement.reasonCode:reasonForUse.text Short description ReasonForUse Alternate names RedenGebruik Definition The reason for using the medication, particularly in self-care medicine purchased by the patient themselves. Requirements The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source. Comments Very often the text is the same as a displayName of one of the codings. Data Type string Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE.9. But note many systems use CE.2 for this rim:./originalText[mediaType/code="text/plain"]/data orim:fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22491 HdBe-MedicationUse2:MedicationUse.ReasonForUse
reasonReference	I	0..*	Reference(Condition \| Observation \| DiagnosticReport)	There are no (further) constraints on this element Element Id MedicationStatement.reasonReference Short description Condition or observation that supports why the medication is being/was taken Definition Condition or observation that supports why the medication is being/was taken. Comments This is a reference to a condition that is the reason why the medication is being/was taken. If only a code exists, use reasonForUseCode. Data Type Reference(Condition \| Observation \| DiagnosticReport) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.reasonReference w5:FiveWs.why[x] rim:.outboundRelationship[typeCode=RSON]/target[classCode=OBS,moodCode=EVN, code="reason for use"].value
note		0..1	Annotation	There are no (further) constraints on this element Element Id MedicationStatement.note Short description Further information about the statement Definition Provides extra information about the medication statement that is not conveyed by the other attributes. Comments For systems that do not have structured annotations, they can simply communicate a single annotation with no author or time. This element may need to be included in narrative because of the potential for modifying information. Annotations SHOULD NOT be used to communicate "modifying" information that could be computable. (This is a SHOULD because enforcing user behavior is nearly impossible). Data Type Annotation Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act workflow:Event.note rim:.inboundRelationship[typeCode=SUBJ]/source[classCode=OBS,moodCode=EVN,code="annotation"].value
author[x]	Σ	0..1		There are no (further) constraints on this element Element Id MedicationStatement.note.author[x] Short description Individual responsible for the annotation Definition The individual responsible for making the annotation. Comments Organization is used when there's no need for specific attribution as to who made the comment. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.participant[typeCode=AUT].role
authorString			string	There are no (further) constraints on this element Data Type string
authorReference			Reference(Practitioner \| Patient \| RelatedPerson \| Organization)	There are no (further) constraints on this element Data Type Reference(Practitioner \| Patient \| RelatedPerson \| Organization)
time	Σ	0..1	dateTime	There are no (further) constraints on this element Element Id MedicationStatement.note.time Short description When the annotation was made Definition Indicates when this particular annotation was made. Data Type dateTime Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.effectiveTime
text	Σ	1..1	markdown	Element Id MedicationStatement.note.text Short description Comment Alternate names Toelichting Definition Comments on the medication use. Comments Systems are not required to have markdown support, so the text should be readable without markdown processing. The markdown syntax is GFM - see https://github.github.com/gfm/ Data Type markdown Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.text zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21624 HdBe-MedicationUse2:MedicationUse.Comment
dosage		0..*	HdBe InstructionsForUse.DosageInstructions	Element Id MedicationStatement.dosage Short description DosingInstructions / InstructionsForUse Alternate names Doseerinstructie, Gebruiksinstructie Definition Instructions for the use of the medication, e.g. dose and route of administration. In the event of medication use, this is the pattern of use established by the patient or which the patient followed. Comments This element mostly represents the DosingInstructions container from CBB InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are duplicated in every repetition of this element, even though these concepts should be present just once according to the CBB. The RepeatPeriodCyclicalSchedule and Description elements of the CBB are not represented in this profile. When a HdBe profile contains a InstructionsForUse.DosageInstructions datatype, the RepeatPeriodCyclicalSchedule and Description elements are separately added to this profile as well. This element does not contain a mapping to the Dosage container from CBB InstructionsForUse. However, the child concepts of Dosage are all mapped. Multiple Dosage instances are represented by another DosingInstructions that contains a similiar SequenceNumber. Data Type HdBe InstructionsForUse.DosageInstructions Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:.outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT] rim:refer dosageInstruction mapping zib-instructionsforuse-v1.2.1-2020EN:NL-CM:9.12.22095 HdBe-InstructionsForUse:InstructionsForUse.DosingInstructions zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22504 HdBe-MedicationUse2:MedicationUse.InstructionsForUse

MedicationStatement	I		MedicationStatement	Element Id MedicationStatement Short description MedicationUse Alternate names MedicatieGebruik Definition A record of a medication that is being consumed by a patient. A MedicationStatement may indicate that the patient may be taking the medication now or has taken the medication in the past or will be taking the medication in the future. The source of this information can be the patient, significant other (such as a family member or spouse), or a clinician. A common scenario where this information is captured is during the history taking process during a patient visit or stay. The medication information may come from sources such as the patient's memory, from a prescription bottle, or from a list of medications the patient, clinician or other party maintains. The primary difference between a medication statement and a medication administration is that the medication administration has complete administration information and is based on actual administration information from the person who administered the medication. A medication statement is often, if not always, less specific. There is no required date/time when the medication was administered, in fact we only know that a source has reported the patient is taking this medication, where details such as time, quantity, or rate or even medication product may be incomplete or missing or less precise. As stated earlier, the medication statement information may come from the patient's memory, from a prescription bottle or from a list of medications the patient, clinician or other party maintains. Medication administration is more formal and is not missing detailed information. Comments When interpreting a medicationStatement, the value of the status and NotTaken needed to be considered: MedicationStatement.status + MedicationStatement.wasNotTaken Status=Active + NotTaken=T = Not currently taking Status=Completed + NotTaken=T = Not taken in the past Status=Intended + NotTaken=T = No intention of taking Status=Active + NotTaken=F = Taking, but not as prescribed Status=Active + NotTaken=F = Taking Status=Intended +NotTaken= F = Will be taking (not started) Status=Completed + NotTaken=F = Taken in past Status=In Error + NotTaken=N/A = In Error. Data Type MedicationStatement Constraints dom-2:If the resource is contained in another resource, it SHALL NOT contain nested Resources `contained.contained.empty()` dom-4:If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated `contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()` dom-3:If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource `contained.where((('#'+id in (%resource.descendants().reference \| %resource.descendants().as(canonical) \| %resource.descendants().as(uri) \| %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()` dom-6:A resource should have narrative for robust management text.`div`.exists() dom-5:If a resource is contained in another resource, it SHALL NOT have a security label `contained.meta.security.empty()` Mappings rim:Entity. Role, or Act workflow:Event rim:SubstanceAdministration zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21338 HdBe-MedicationUse2:MedicationUse
extension	I	0..*	Extension	Element Id MedicationStatement.extension Short description Additional content defined by implementations Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension Sliced: Unordered, Open, by url(Value) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
renderedDosageInstruction	I	0..1	Extension(string)	Element Id MedicationStatement.extension:renderedDosageInstruction Short description Optional Extensions Element Alternate names extensions, user content Definition Pre-adopt from FHIR R5 of the `.renderedDosageInstruction` element found in various medication resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(string) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-RenderedDosageInstruction Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:renderedDosageInstruction.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-RenderedDosageInstruction Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.extension:renderedDosageInstruction.value[x] Short description Value of extension Definition The full representation of the dose of the medication included in all dosage instructions. To be used when multiple dosage instructions are included to represent complex dosing such as increasing or tapering doses. Comments The content of the renderedDosageInstructions must not be different than the dose represented in the dosageInstruction content. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A HdBe-InstructionsForUse:InstructionsForUse.Description
valueString			string	There are no (further) constraints on this element Data Type string
prescriber	I	0..1	Extension(pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner))	Element Id MedicationStatement.extension:prescriber Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.Prescriber Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:prescriber.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.Prescriber Mappings rim:N/A
value[x]	I	0..1		Element Id MedicationStatement.extension:prescriber.value[x] Short description Prescriber Alternate names Voorschrijver Definition The health professional that entered the medication agreement with the patient. Comments Each occurrence of the CBB HealthProfessional is normally represented by two FHIR resources: a PractitionerRole resource (instance of HdBe-HealthProfessional-PractitionerRole) and a Practitioner resource (instance of HdBe-HealthProfessional-Practitioner). The Practitioner resource is referenced from the PractitionerRole instance. For this reason, sending systems should fill the reference to the PractitionerRole instance here, and not the Practitioner resource. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:N/A rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23290 HdBe-MedicationUse2:MedicationUse.Prescriber
valueReference			pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)	There are no (further) constraints on this element Data Type pattern HealthProfessional Reference(HdBe HealthProfessional PractitionerRole \| HdBe HealthProfessional Practitioner)
asAgreedIndicator	I	0..1	Extension(boolean)	Element Id MedicationStatement.extension:asAgreedIndicator Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(boolean) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.AsAgreedIndicator Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.extension:asAgreedIndicator.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-MedicationUse2.AsAgreedIndicator Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.extension:asAgreedIndicator.value[x] Short description AsAgreedIndicator Alternate names VolgensAfspraakIndicator Definition Duration: The intended duration of use. E.g. 5 days or 8 weeks. It is not allowed to indicate the duration in months, because different months have a variable duration in days. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22492 HdBe-MedicationUse2:MedicationUse.AsAgreedIndicator
valueBoolean			boolean	There are no (further) constraints on this element Data Type boolean
modifierExtension	?! I	0..*	Extension	Element Id MedicationStatement.modifierExtension Short description Extensions that cannot be ignored Alternate names extensions, user content Definition May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself). Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension Sliced: Unordered, Open, by url(Value) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
stopType	?! I	0..1	Extension(CodeableConcept)	Element Id MedicationStatement.modifierExtension:stopType Short description Optional Extensions Element Alternate names extensions, user content Definition This StopType ModifierExtension works differently than the `.status` element of resources because it has a different meaning. The `.status` element represents the status of the resource at the moment of exchanging the resource. This means that over the lifetime of a resource, the status may change (and is very much related to use period). That – in itself – makes mapping StopType (which may never change in an instance) to status not suitable. For example: suppose you want the patient to stop taking medication definitively three days from today. This is a stop medication agreement with a StopType of definitive. However today, tomorrow and the day after tomorrow the `.status` of this medication agreement is active and only after the end date of the usage period the `status` should be stopped. Status and StopType are simply not the same thing. Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(CodeableConcept) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-StopType Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.modifierExtension:stopType.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-StopType Mappings rim:N/A
value[x]		0..1	Binding	Element Id MedicationStatement.modifierExtension:stopType.value[x] Short description MedicationUseStopType Alternate names MedicatieGebruikStopType Definition Stop type, the manner in which this medication is discontinued (temporary or definitive). Comments MedicationAgreementStopType, AdministrationAgreementStopType and MedicationUseStopType all have a bound ValueSet that contain the exact same StopType values. These are represented in the CBB with the same Valueset. This MedicationStopType is used to bind to this extension and reusing this extension for all three concepts. Binding StopType values, based on the valueset named MedicatioStopType, which are applicable for StopType in MedicationAgreement, AdministrationAgreement and MedicationUse. MedicationStopType (required) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23132 HdBe-MedicationUse2:MedicationUse.MedicationUseStopType
valueCodeableConcept			CodeableConcept	There are no (further) constraints on this element Data Type CodeableConcept
repeatPeriodCyclicalSchedule	?! I	0..1	Extension(Duration)	Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule Short description Optional Extensions Element Alternate names extensions, user content Definition Optional Extension Element - found in all resources. Requirements Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Comments There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone. Data Type Extension(Duration) Extension URL https://fhir.healthdata.be/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ext-1:Must have either extensions or value[x], not both `extension.exists() != value.exists()` Mappings rim:n/a rim:N/A
url		1..1	System.StringFixed Value	There are no (further) constraints on this element Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.url Short description identifies the meaning of the extension Definition Source of the definition for the extension code - a logical name or a URL. Comments The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension. Data Type System.String Fixed Value https://fhir.healthdata.be/StructureDefinition/ext-InstructionsForUse.RepeatPeriodCyclicalSchedule Mappings rim:N/A
value[x]		0..1		Element Id MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.value[x] Short description RepeatPeriodCyclicalSchedule Alternate names HerhaalperiodeCyclischSchema Definition The repeated period in a cyclical schedule (of one or more dosing instructions). A cyclic schedule is noted in days, the corresponding dosing duration is also in days. Examples of a cyclical schedule: contraceptive pill (21 days, 1 pill 1x a day, then skip for 7 days, repeat), repeat period here is 28 days Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:N/A zib-instructionsforuse-v1.2.1-2020EN:NL-CM:9.12.22505 HdBe-InstructionsForUse:InstructionsForUse.RepeatPeriodCyclicalSchedule
valueDuration			Duration	There are no (further) constraints on this element Data Type Duration
identifier	Σ	0..*	Identifier	There are no (further) constraints on this element Element Id MedicationStatement.identifier Short description External identifier Definition Identifiers associated with this Medication Statement that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate. They are business identifiers assigned to this resource by the performer or other systems and remain constant as the resource is updated and propagates from server to server. Comments This is a business identifier, not a resource identifier. Data Type Identifier Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CX / EI (occasionally, more often EI maps to a resource id or a URL) rim:II - The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs. Also maps to Role[classCode=IDENT] servd:Identifier workflow:Event.identifier w5:FiveWs.identifier rim:.id
basedOn	Σ I	0..*	Reference(MedicationRequest \| CarePlan \| ServiceRequest)	There are no (further) constraints on this element Element Id MedicationStatement.basedOn Short description Fulfils plan, proposal or order Definition A plan, proposal or order that is fulfilled in whole or in part by this event. Requirements Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(MedicationRequest \| CarePlan \| ServiceRequest) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.basedOn rim:.outboundRelationship[typeCode=FLFS].target[classCode=SBADM or PROC or PCPR or OBS, moodCode=RQO orPLAN or PRP]
partOf	Σ I	0..*	Reference(MedicationAdministration \| MedicationDispense \| MedicationStatement \| Procedure \| Observation)	There are no (further) constraints on this element Element Id MedicationStatement.partOf Short description Part of referenced event Definition A larger event of which this particular event is a component or step. Requirements This should not be used when indicating which resource a MedicationStatement has been derived from. If that is the use case, then MedicationStatement.derivedFrom should be used. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(MedicationAdministration \| MedicationDispense \| MedicationStatement \| Procedure \| Observation) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.partOf rim:.outboundRelationship[typeCode=COMP]/target[classCode=SPLY or SBADM or PROC or OBS,moodCode=EVN]
status	Σ ?!	1..1	codeBinding	Element Id MedicationStatement.status Short description UseIndicator / MedicationUseStopType / PeriodOfUse Alternate names MedicatieGebruikStopType, GebruikIndicator, Gebruiksperiode Definition Status may contain information on the stop type, the manner in which this medication is discontinued (temporary or definitive) and if the medicine is used or not. Comments This element is mapped to the CBB concept UseIndicator and implicitly to MedicationUseStopType and PeriodOfUse. Unless a more appropriate status is recorded, the following guidance applies: When MedicationUseStopType has no value and UseIndicator is true, `.status` will usually be set to active. When UseIndicator is false, `.status` will be set to not-taken. When MedicationUseStopType is 14803004, `.status` will usually be set to on-hold. When MedicationUseStopType is 255545003, `.status` will usually be set to stopped. When PeriodOfUse start date is in the past and PeriodOfUse end date is present and in the future, `.status` will usually be set to active. When PeriodOfUse end date has a value and in the past, `.status` will usually be set to completed. When PeriodOfUse duration and start date are known, the end date can be deducted and the previous rules apply. When a system is unable to infer the status, `.status` will be set to unknown. The unknown code is not to be used to convey other statuses. The unknown code should be used when one of the statuses applies, but the authoring system doesn't know the current state of the MedicationStatement. Data Type code Binding Use ConceptMap 'MedicationStopType-to-MedicationStatementStatus' to translate CBB terminology to profile terminology in ValueSet 'Medication Status Codes'. Medication Status Codes (required) Permitted Values MedicationStopType_to_MedicationStatementStatus Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.status w5:FiveWs.status rim:.statusCode zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22399 zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.23132 zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22663 HdBe-MedicationUse2:MedicationUse.UseIndicator HdBe-MedicationUse2:MedicationUse.MedicationUseStopType HdBe-MedicationUse2:MedicationUse.PeriodOfUse
statusReason		0..*	CodeableConceptBinding	Element Id MedicationStatement.statusReason Short description ReasonForChangeOrDiscontinuationOfUse Alternate names RedenWijzigenOfStoppenGebruik Definition Reason for changing or discontinuing use of medication. Comments This is generally only used for "exception" statuses such as "not-taken", "on-hold", "cancelled" or "entered-in-error". The reason for performing the event at all is captured in reasonCode, not here. Data Type CodeableConcept Binding A coded concept indicating the reason for the status of the statement. MedicationReason (required) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.statusReason rim:.inboundRelationship[typeCode=SUBJ].source[classCode=CACT, moodCode=EVN].reasonCOde zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22493 HdBe-MedicationUse2:MedicationUse.ReasonForChangeOrDiscontinuationOfUse
category	Σ	1..1	CodeableConceptBinding	Element Id MedicationStatement.category Short description Type of medication usage Definition Indicates where the medication is expected to be consumed or administered. Comments Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination. Data Type CodeableConcept Binding A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered. Medication usage category codes (preferred) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Pattern { "coding": [ { "system": "http://snomed.info/sct", "code": "422979000" } ] } Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD w5:FiveWs.class rim:.inboundRelationship[typeCode=COMP].source[classCode=OBS, moodCode=EVN, code="type of medication usage"].value
medication[x]	Σ	1..1		Element Id MedicationStatement.medication[x] Short description What medication was taken Definition Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications. Comments If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource. Sliced: Unordered, Open, by $this(Type) Binding A coded concept identifying the substance or product being taken. SNOMEDCTMedicationCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.code w5:FiveWs.what[x] rim:.participation[typeCode=CSM].role[classCode=ADMM or MANU]
medicationCodeableConcept			CodeableConcept	There are no (further) constraints on this element Data Type CodeableConcept
medicationReference	Σ	0..1	Reference(Medication \| HdBe PharmaceuticalProduct)	Element Id MedicationStatement.medication[x]:medicationReference Short description ProductUsed Alternate names Gebruiksproduct Definition The product used. This is usually medication. Food, blood products, aids and bandages do not strictly fall under the category of medication, but can be recorded as well. In principle, this will be the prescribed product, but the product used may differ from the prescribed product. Comments If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended. For example, if you require form or lot number, then you must reference the Medication resource. Data Type Reference(Medication \| HdBe PharmaceuticalProduct) Binding A coded concept identifying the substance or product being taken. SNOMEDCTMedicationCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.code w5:FiveWs.what[x] rim:.participation[typeCode=CSM].role[classCode=ADMM or MANU] zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21339 HdBe-MedicationUse2:MedicationUse.ProductUsed
subject	Σ I	1..1	Reference(Group \| HdBe Patient)	Element Id MedicationStatement.subject Short description Who is/was taking the medication Definition The person, animal or group who is/was taking the medication. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Group \| HdBe Patient) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.subject w5:FiveWs.subject[x] v2:PID-3-Patient ID List rim:.participation[typeCode=SBJ].role[classCode=PAT] w5:FiveWs.subject
context	Σ I	0..1	Reference(Encounter \| EpisodeOfCare)	There are no (further) constraints on this element Element Id MedicationStatement.context Short description Encounter / Episode associated with MedicationStatement Definition The encounter or episode of care that establishes the context for this MedicationStatement. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Encounter \| EpisodeOfCare) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.context rim:.inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN, code="type of encounter or episode"]
effective[x]	Σ	0..1		Element Id MedicationStatement.effective[x] Short description The date/time or interval when the medication is/was/will be taken Definition The interval of time during which it is being asserted that the patient is/was/will be taking the medication (or was not taking, when the MedicationStatement.taken element is No). Comments This attribute reflects the period over which the patient consumed the medication and is expected to be populated on the majority of Medication Statements. If the medication is still being taken at the time the statement is recorded, the "end" date will be omitted. The date/time attribute supports a variety of dates - year, year/month and exact date. If something more than this is required, this should be conveyed as text. Sliced: Unordered, Open, by $this(Type) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a workflow:Event.occurrence[x] w5:FiveWs.done[x] rim:.effectiveTime
effectiveDateTime			dateTime	There are no (further) constraints on this element Data Type dateTime
effectivePeriod	Σ I	0..1	HdBe TimeInterval	Element Id MedicationStatement.effective[x]:effectivePeriod Short description PeriodOfUse Alternate names Gebruiksperiode Definition Medication use can be recorded for a certain moment or over a certain period. Thus, medication use can be recorded multiple times during the use of medication. The usage period is the period or moment over which the data is recorded. Start date: This is the time at which the agreement was to take effect (or took effect or will take effect). End date: The time at which the period of use ends (or ended or will end). To avoid confusion between 'to' and 'up to', the submission of time is always mandatory for the end date. Comments A Period specifies a range of time; the context of use will specify whether the entire range applies (e.g. "the patient was an inpatient of the hospital for this time range") or one value from the range applies (e.g. "give to the patient between these two times"). Period is not used for a duration (a measure of elapsed time). See Duration. Data Type HdBe TimeInterval Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` per-1:If present, start SHALL have a lower value than end `start.hasValue().not() or end.hasValue().not() or (start <= end)` Mappings rim:n/a workflow:Event.occurrence[x] w5:FiveWs.done[x] rim:.effectiveTime v2:DR rim:IVL<TS>[lowClosed="true" and highClosed="true"] or URG<TS>[lowClosed="true" and highClosed="true"] HdBe-TimeInterval:TimeInterval zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22663 HdBe-MedicationUse2:MedicationUse.PeriodOfUse
dateAsserted	Σ	0..1	dateTime	Element Id MedicationStatement.dateAsserted Short description MedicationUseDateTime Alternate names MedicatieGebruikDatumTijd Definition Date on which this use is entered. Data Type dateTime Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a w5:FiveWs.recorded rim:.participation[typeCode=AUT].time zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22398 HdBe-MedicationUse2:MedicationUse.MedicationUseDateTime
informationSource	I	0..1	Reference(Patient \| Practitioner \| PractitionerRole \| RelatedPerson \| Organization)	There are no (further) constraints on this element Element Id MedicationStatement.informationSource Short description Person or organization that provided the information about the taking of this medication Definition The person or organization that provided the information about the taking of this medication. Note: Use derivedFrom when a MedicationStatement is derived from other resources, e.g. Claim or MedicationRequest. Comments References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc.). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository. Data Type Reference(Patient \| Practitioner \| PractitionerRole \| RelatedPerson \| Organization) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) w5:FiveWs.source rim:.participation[typeCode=INF].role[classCode=PAT, or codes for Practioner or Related Person (if PAT is the informer, then syntax for self-reported =true)
derivedFrom	I	0..*	Reference(Resource)	There are no (further) constraints on this element Element Id MedicationStatement.derivedFrom Short description Additional supporting information Definition Allows linking the MedicationStatement to the underlying MedicationRequest, or to other information that supports or is used to derive the MedicationStatement. Comments Likely references would be to MedicationRequest, MedicationDispense, Claim, Observation or QuestionnaireAnswers. The most common use cases for deriving a MedicationStatement comes from creating a MedicationStatement from a MedicationRequest or from a lab observation or a claim. it should be noted that the amount of information that is available varies from the type resource that you derive the MedicationStatement from. Data Type Reference(Resource) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) rim:.outboundRelationship[typeCode=SPRT]/target[classCode=ACT,moodCode=EVN]
reasonCode		0..*	CodeableConcept	Element Id MedicationStatement.reasonCode Short description Reason for why the medication is being/was taken Definition A reason for why the medication is being/was taken. Comments This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference. Data Type CodeableConcept Sliced: Unordered, Open, by text(Exists) Binding A coded concept identifying why the medication is being taken. Condition/Problem/DiagnosisCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.reasonCode w5:FiveWs.why[x] rim:.reasonCode
reasonForUse		0..1	CodeableConcept	There are no (further) constraints on this element Element Id MedicationStatement.reasonCode:reasonForUse Short description Reason for why the medication is being/was taken Definition A reason for why the medication is being/was taken. Comments This could be a diagnosis code. If a full condition record exists or additional detail is needed, use reasonForUseReference. Data Type CodeableConcept Binding A coded concept identifying why the medication is being taken. Condition/Problem/DiagnosisCodes (example) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE rim:CD orim:fhir:CodeableConcept rdfs:subClassOf dt:CD workflow:Event.reasonCode w5:FiveWs.why[x] rim:.reasonCode
coding	Σ	0..*	Coding	There are no (further) constraints on this element Element Id MedicationStatement.reasonCode:reasonForUse.coding Short description Code defined by a terminology system Definition A reference to a code defined by a terminology system. Requirements Allows for alternative encodings within a code system, and translations to other code systems. Comments Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true. Data Type Coding Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE/CNE/CWE subset one of the sets of component 1-3 or 4-6 rim:CV orim:fhir:Coding rdfs:subClassOf dt:CDCoding v2:CE.1-8, CE.10-22 rim:union(., ./translation) orim:fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding
text	Σ	1..1	string	Element Id MedicationStatement.reasonCode:reasonForUse.text Short description ReasonForUse Alternate names RedenGebruik Definition The reason for using the medication, particularly in self-care medicine purchased by the patient themselves. Requirements The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source. Comments Very often the text is the same as a displayName of one of the codings. Data Type string Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:CE.9. But note many systems use CE.2 for this rim:./originalText[mediaType/code="text/plain"]/data orim:fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22491 HdBe-MedicationUse2:MedicationUse.ReasonForUse
reasonReference	I	0..*	Reference(Condition \| Observation \| DiagnosticReport)	There are no (further) constraints on this element Element Id MedicationStatement.reasonReference Short description Condition or observation that supports why the medication is being/was taken Definition Condition or observation that supports why the medication is being/was taken. Comments This is a reference to a condition that is the reason why the medication is being/was taken. If only a code exists, use reasonForUseCode. Data Type Reference(Condition \| Observation \| DiagnosticReport) Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` ref-1:SHALL have a contained resource if a local reference is provided `reference.startsWith('#').not() or (reference.substring(1).trace('url') in %rootResource.contained.id.trace('ids'))` Mappings rim:n/a rim:The target of a resource reference is a RIM entry point (Act, Role, or Entity) workflow:Event.reasonReference w5:FiveWs.why[x] rim:.outboundRelationship[typeCode=RSON]/target[classCode=OBS,moodCode=EVN, code="reason for use"].value
note		0..1	Annotation	There are no (further) constraints on this element Element Id MedicationStatement.note Short description Further information about the statement Definition Provides extra information about the medication statement that is not conveyed by the other attributes. Comments For systems that do not have structured annotations, they can simply communicate a single annotation with no author or time. This element may need to be included in narrative because of the potential for modifying information. Annotations SHOULD NOT be used to communicate "modifying" information that could be computable. (This is a SHOULD because enforcing user behavior is nearly impossible). Data Type Annotation Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act workflow:Event.note rim:.inboundRelationship[typeCode=SUBJ]/source[classCode=OBS,moodCode=EVN,code="annotation"].value
author[x]	Σ	0..1		There are no (further) constraints on this element Element Id MedicationStatement.note.author[x] Short description Individual responsible for the annotation Definition The individual responsible for making the annotation. Comments Organization is used when there's no need for specific attribution as to who made the comment. Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.participant[typeCode=AUT].role
authorString			string	There are no (further) constraints on this element Data Type string
authorReference			Reference(Practitioner \| Patient \| RelatedPerson \| Organization)	There are no (further) constraints on this element Data Type Reference(Practitioner \| Patient \| RelatedPerson \| Organization)
time	Σ	0..1	dateTime	There are no (further) constraints on this element Element Id MedicationStatement.note.time Short description When the annotation was made Definition Indicates when this particular annotation was made. Data Type dateTime Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.effectiveTime
text	Σ	1..1	markdown	Element Id MedicationStatement.note.text Short description Comment Alternate names Toelichting Definition Comments on the medication use. Comments Systems are not required to have markdown support, so the text should be readable without markdown processing. The markdown syntax is GFM - see https://github.github.com/gfm/ Data Type markdown Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a v2:N/A rim:Act.text zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.21624 HdBe-MedicationUse2:MedicationUse.Comment
dosage		0..*	HdBe InstructionsForUse.DosageInstructions	Element Id MedicationStatement.dosage Short description DosingInstructions / InstructionsForUse Alternate names Doseerinstructie, Gebruiksinstructie Definition Instructions for the use of the medication, e.g. dose and route of administration. In the event of medication use, this is the pattern of use established by the patient or which the patient followed. Comments This element mostly represents the DosingInstructions container from CBB InstructionsForUse, but also includes the AdditionalInstructions and RouteOfAdministration concepts, which are normally placed on the same level as this container. As a result, these concepts are duplicated in every repetition of this element, even though these concepts should be present just once according to the CBB. The RepeatPeriodCyclicalSchedule and Description elements of the CBB are not represented in this profile. When a HdBe profile contains a InstructionsForUse.DosageInstructions datatype, the RepeatPeriodCyclicalSchedule and Description elements are separately added to this profile as well. This element does not contain a mapping to the Dosage container from CBB InstructionsForUse. However, the child concepts of Dosage are all mapped. Multiple Dosage instances are represented by another DosingInstructions that contains a similiar SequenceNumber. Data Type HdBe InstructionsForUse.DosageInstructions Constraints ele-1:All FHIR elements must have a @value or children `hasValue() or (children().count() > id.count())` Mappings rim:n/a rim:.outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT] rim:refer dosageInstruction mapping zib-instructionsforuse-v1.2.1-2020EN:NL-CM:9.12.22095 HdBe-InstructionsForUse:InstructionsForUse.DosingInstructions zib-medicationuse2-v1.1.1-2020EN:NL-CM:9.11.22504 HdBe-MedicationUse2:MedicationUse.InstructionsForUse

Mapping FHIR profile to CBB

Path	map	CBB	comment
MedicationStatement.extension:renderedDosageInstruction.value[x]	InstructionsForUse.Description	HdBe-InstructionsForUse
MedicationStatement.modifierExtension:repeatPeriodCyclicalSchedule.value[x]	InstructionsForUse.RepeatPeriodCyclicalSchedule	HdBe-InstructionsForUse
MedicationStatement	MedicationUse	HdBe-MedicationUse2
MedicationStatement.extension:prescriber.value[x]	MedicationUse.Prescriber	HdBe-MedicationUse2
MedicationStatement.extension:asAgreedIndicator.value[x]	MedicationUse.AsAgreedIndicator	HdBe-MedicationUse2
MedicationStatement.modifierExtension:stopType.value[x]	MedicationUse.MedicationUseStopType	HdBe-MedicationUse2
MedicationStatement.status	MedicationUse.UseIndicator	HdBe-MedicationUse2
MedicationStatement.status	MedicationUse.MedicationUseStopType	HdBe-MedicationUse2	implicit, main mapping is on the modifier extension ext-StopType
MedicationStatement.status	MedicationUse.PeriodOfUse	HdBe-MedicationUse2	implicit, main mapping is on `.effective[x]:effectivePeriod` and extension ext-TimeInterval.Duration
MedicationStatement.statusReason	MedicationUse.ReasonForChangeOrDiscontinuationOfUse	HdBe-MedicationUse2
MedicationStatement.medication[x]:medicationReference	MedicationUse.ProductUsed	HdBe-MedicationUse2
MedicationStatement.effective[x]:effectivePeriod	MedicationUse.PeriodOfUse	HdBe-MedicationUse2
MedicationStatement.dateAsserted	MedicationUse.MedicationUseDateTime	HdBe-MedicationUse2
MedicationStatement.reasonCode:reasonForUse.text	MedicationUse.ReasonForUse	HdBe-MedicationUse2
MedicationStatement.note.text	MedicationUse.Comment	HdBe-MedicationUse2
MedicationStatement.dosage	MedicationUse.InstructionsForUse	HdBe-MedicationUse2

HdBe-MedicationUse2-01

zib MedicationUse2 difference

| Concept | Category | Description | |-----------------|-------------------|-----------------------------------------| |status | terminology | Replaced values of ConceptMap MedicationStopType-to-MedicationStatementStatus in correspondence with changes of ValueSet MedicationStopType. | |status | textual | Replaced Dutch SNOMED-CT codes with the corresponding codes in the ValueSet MedicationStopType in the guidance on the correct use of status. | |statusReason | terminology | Renamed the ValueSet from ReasonForChangeOrDiscontinuationOfUse to MedicationReason, to be able to reuse it at MedicationAgreement. Replaced several values in MedicationReason valueSet : 1. Replaced OTH with SNOMED-CT code for Other. 2. Added SNOMED-CT code for Unknown. 3. Added CodeSystem MedicationReason which replaces all Dutch SNOMED-CT codes. 4. Removed all Dutch SNOMED-CT codes from valueset. | modifierExtension:stopType | textual | Edited guidance on the reuse of the MedicationStopType ValueSet. | | modifierExtension:stopType | terminology | Renamed the ValueSet from MedicationUseStopType to MedicationStopType, to be able to reuse it in MedicationAgreement and AdministrationAgreement. Replaced Dutch SNOMED-CT codes with international codes. | |extension:prescriber.value[x] | reference | Added reference to HdBe-HealthProfessional-Practitioner as it should be possible to reference to Practitioner directly using the pattern. |

Terminology Bindings

Path	Name	Strength	URL	ConceptMap
MedicationStatement.status	medication-statement-status\|4.0.1	required	http://hl7.org/fhir/ValueSet/medication-statement-status\|4.0.1	https://fhir.healthdata.be/ConceptMap/MedicationStopType-to-MedicationStatementStatus
MedicationStatement.statusReason	MedicationReason	required	https://fhir.healthdata.be/ValueSet/MedicationReason	No bound ConceptMap