Notice
- Important: This guidance is under active development by NHS England and content may be added or updated on a regular basis.
- This Implementation Guide is currently in Draft and SHOULD NOT be used for development or active implementation without express direction from the NHS England Genomics Unit.
Bundle-NonWGSScenario5-ProductsofConception-Example
Example of a Non-WGS test request sent to the central broker, as described in the Clinical Scenario:Fetus Management
| Bundle |
| id : Bundle-NonWGSScenario5-ProductsofConception-Example |
| type : transaction |
| entry |
| fullUrl : urn:uuid:cf37712a-99c8-495b-9865-a96fffe5133c |
| resource |
| id : cf37712a-99c8-495b-9865-a96fffe5133c |
| identifier |
| system : https://fhir.nhs.uk/Id/GMSCompoundIdentifer |
| value : RYJ02:https://fhir.nhs.uk/Id/sds-user-id:2441541066 |
| practitioner |
| identifier |
| system : https://fhir.nhs.uk/Id/sds-user-id |
| value : 2441541066 |
| display : Dr. Lois Lane |
| organization |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : RYJ02 |
| display : Charing Cross Hospital |
| specialty |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-PracticeSettingCode |
| code : 311 |
| display : Clinical Genetics |
| telecom |
| system : phone |
| value : 02085467711 |
| telecom |
| system : email |
| value : Hazel.smith12@nhs.net |
| telecom |
| extension |
| url : http://hl7.org/fhir/StructureDefinition/contactpoint-comment |
| value : reporting |
| system : email |
| value : clinicalgeneticskingston@nhs.net |
| telecom |
| extension |
| url : http://hl7.org/fhir/StructureDefinition/contactpoint-comment |
| value : reporting |
| system : email |
| value : fetalmedicinekingston@nhs.net |
| telecom |
| extension |
| url : http://hl7.org/fhir/StructureDefinition/contactpoint-comment |
| value : reporting |
| system : email |
| value : gptestpracticekingston@nhs.net |
| request |
| method : POST |
| url : PractitionerRole |
| entry |
| fullUrl : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| resource |
| id : c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| extension |
| url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-BirthSex |
| value |
| coding |
| system : http://terminology.hl7.org/CodeSystem/v3-AdministrativeGender |
| code : F |
| display : Female |
| extension |
| url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-EthnicCategory |
| value |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-EthnicCategoryEngland |
| code : A |
| display : White - British |
| identifier |
| extension |
| url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSNumberVerificationStatus |
| value |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSNumberVerificationStatusEngland |
| version : 1.1.1 |
| code : 01 |
| display : Number present and verified |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| identifier |
| system : urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24 |
| value : 71636034 |
| assigner |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : RAX01 |
| name |
| given : Ryanne |
| family : Boulder |
| link |
| other |
| reference : https://int.api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449308322 |
| type : seealso |
| request |
| method : POST |
| url : Patient |
| ifNoneExist : Patient?identifier=https://fhir.nhs.uk/Id/nhs-number|9449308322 |
| entry |
| fullUrl : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
| resource |
| id : 037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
| extension |
| url : http://hl7.org/fhir/6.0/StructureDefinition/extension-Patient.fetalStatus |
| value : fetal-demise |
| identifier |
| system : urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24 |
| value : FoetusA |
| assigner |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : RAX |
| name |
| family : Fetus A of MUM |
| gender : female |
| deceased : 2024-05-16T00:00:00-05:00 |
| link |
| other |
| reference : urn:uuid:ac29fd1f-6749-4771-9633-25f39976e48a |
| type : RelatedPerson |
| type : seealso |
| request |
| method : POST |
| url : Patient |
| ifNoneExist : Patient?identifier=urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24|FoetusA |
| entry |
| fullUrl : urn:uuid:a0684de7-7cf5-43a3-b3ba-3dd13e4c2f4f |
| resource |
| id : a0684de7-7cf5-43a3-b3ba-3dd13e4c2f4f |
| status : final |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 723621000000103 |
| display : Ethnicity |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| value : unknown |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:a5838f88-99af-4ef9-bcb6-150781680d4d |
| resource |
| id : a5838f88-99af-4ef9-bcb6-150781680d4d |
| extension |
| url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage |
| value |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory |
| code : nhs-england |
| display : NHS England |
| identifier |
| system : https://fhir.nhs.uk/Id/GMSOrder |
| value : 5562279a-bb88-45ef-8fbc-b62c09fbbdb2 |
| basedOn |
| reference : ServieRequest/ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example |
| status : active |
| intent : order |
| category |
| coding |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory |
| code : rare-disease-non-wgs |
| display : Rare Disease - Non-WGS |
| priority : urgent |
| code |
| coding |
| system : https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory |
| version : 7 |
| code : R21.1 |
| display : Fetal anomalies with a likely genetic cause |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| authoredOn : 2025-09-05 |
| requester |
| reference : urn:uuid:cf37712a-99c8-495b-9865-a96fffe5133c |
| type : PractitionerRole |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : RYJ02 |
| performer |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : 699N0 |
| reasonCode |
| coding |
| system : https://fhir.nhs.uk/CodeSystem/reasonfortesting-genomics |
| code : staging-or-prognosis |
| display : Staging or Prognosis |
| supportingInfo |
| reference : urn:uuid:3e58d52e-aff3-4a70-956b-28509c664f59 |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:193e30bd-6827-468d-b9b7-0849278305db |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:a0684de7-7cf5-43a3-b3ba-3dd13e4c2f4f |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:554cddd5-7b36-4931-aef2-e96c7fc1f322 |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:e8f9a82e-4a01-4449-9c80-c4d38090884f |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:e1858a31-b153-4525-83d6-805cb682df28 |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:5398e192-d44a-4e07-9cdb-63cdeb4ed47a |
| type : Observation |
| supportingInfo |
| reference : urn:uuid:fe049bb9-7988-4209-a5a7-364f7829950d |
| type : Procedure |
| supportingInfo |
| reference : urn:uuid:ac29fd1f-6749-4771-9633-25f39976e48a |
| type : RelatedPerson |
| supportingInfo |
| reference : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
| type : Patient |
| specimen |
| reference : urn:uuid:6c83fb14-0eb9-465b-8d2c-062b03b12371 |
| type : Specimen |
| note |
| text : Samples are to be provided at a later date |
| note |
| text : No family history of relevant testing |
| note |
| text : Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder |
| request |
| method : POST |
| url : ServiceRequest |
| entry |
| fullUrl : urn:uuid:3e58d52e-aff3-4a70-956b-28509c664f59 |
| resource |
| id : 3e58d52e-aff3-4a70-956b-28509c664f59 |
| status : final |
| category |
| coding |
| system : http://terminology.hl7.org/CodeSystem/observation-category |
| code : social-history |
| display : Social History |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 267013003 |
| display : Past pregnancy outcome |
| text : Outcome of pregnancy |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| effective : 2025-08-25 |
| value |
| coding |
| system : http://snomed.info/sct |
| code : 237365001 |
| display : Fresh stillbirth |
| text : a fetal death occurring at or after 28 weeks of pregnancy |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:554cddd5-7b36-4931-aef2-e96c7fc1f322 |
| resource |
| id : 554cddd5-7b36-4931-aef2-e96c7fc1f322 |
| status : final |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 77386006 |
| display : Pregnancy |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| effective : 2025-08-25 |
| component |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 720451000000102 |
| display : Assisted conception |
| component |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 226081000000107 |
| display : Gestational age |
| value |
| value : 87 |
| unit : day |
| system : http://unitsofmeasure.org |
| code : d |
| component |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 161714006 |
| display : Estimated date of delivery |
| value : 2025-08-25 |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:193e30bd-6827-468d-b9b7-0849278305db |
| resource |
| id : 193e30bd-6827-468d-b9b7-0849278305db |
| status : final |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 160475008 |
| display : Family history of consanguinity |
| subject |
| reference : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
| type : Patient |
| effective : 2025-08-25 |
| value : False |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:e8f9a82e-4a01-4449-9c80-c4d38090884f |
| resource |
| id : e8f9a82e-4a01-4449-9c80-c4d38090884f |
| status : final |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 416128008 |
| display : No history of procedure |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| effective : 2025-08-25 |
| value |
| coding |
| system : http://snomed.info/sct |
| code : 263903005 |
| display : Transplant |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:e1858a31-b153-4525-83d6-805cb682df28 |
| resource |
| id : e1858a31-b153-4525-83d6-805cb682df28 |
| status : final |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 609520005 |
| display : Disorder of fetal structure |
| text : First Trimester Anomalies? |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| effective : 2025-08-25 |
| value : False |
| component |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 255246003 |
| display : First trimester |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:5398e192-d44a-4e07-9cdb-63cdeb4ed47a |
| resource |
| id : 5398e192-d44a-4e07-9cdb-63cdeb4ed47a |
| status : final |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 609520005 |
| display : Disorder of fetal structure |
| text : Second Trimester Anomalies? |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| effective : 2025-08-25 |
| value : False |
| component |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 255247007 |
| display : Second trimester |
| request |
| method : POST |
| url : Observation |
| entry |
| fullUrl : urn:uuid:fe049bb9-7988-4209-a5a7-364f7829950d |
| resource |
| id : fe049bb9-7988-4209-a5a7-364f7829950d |
| status : completed |
| code |
| coding |
| system : http://snomed.info/sct |
| code : 52637005 |
| display : In vitro fertilisation |
| subject |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| performed : 2025-05-25 |
| note |
| text : Woman`s own egg |
| request |
| method : POST |
| url : Procedure |
| entry |
| fullUrl : urn:uuid:6c83fb14-0eb9-465b-8d2c-062b03b12371 |
| resource |
| id : 6c83fb14-0eb9-465b-8d2c-062b03b12371 |
| meta |
| tag |
| system : https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory |
| code : nhs-england |
| display : NHS England |
| identifier |
| system : https://fhir.add.nhs.uk/Id/specimenId |
| value : RGT19427897 |
| status : unavailable |
| type |
| coding |
| system : http://snomed.info/sct |
| code : 258565009 |
| display : Chorionic villi specimen |
| subject |
| reference : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
| type : Patient |
| request |
| reference : ServieRequest/ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example |
| type : ServiceRequest |
| request |
| method : POST |
| url : Specimen |
| entry |
| fullUrl : urn:uuid:ac29fd1f-6749-4771-9633-25f39976e48a |
| resource |
| id : ac29fd1f-6749-4771-9633-25f39976e48a |
| identifier |
| system : urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24 |
| value : 6988036185 |
| assigner |
| identifier |
| system : https://fhir.nhs.uk/Id/ods-organization-code |
| value : RAX |
| patient |
| reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
| type : Patient |
| identifier |
| system : https://fhir.nhs.uk/Id/nhs-number |
| value : 9449308322 |
| relationship |
| coding |
| system : http://terminology.hl7.org/CodeSystem/v3-RoleCode |
| code : NCHILD |
| display : natural child |
| request |
| method : POST |
| url : RelatedPerson |
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"text": "Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder"
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<PractitionerRole>
</identifier>
</identifier>
</practitioner>
</identifier>
</organization>
</coding>
</specialty>
</telecom>
</telecom>
</extension>
</telecom>
</extension>
</telecom>
</extension>
</telecom>
</PractitionerRole>
</resource>
</request>
</entry>
<Patient>
</coding>
</valueCodeableConcept>
</extension>
</coding>
</valueCodeableConcept>
</extension>
<extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSNumberVerificationStatus">
</coding>
</valueCodeableConcept>
</extension>
</identifier>
</identifier>
</assigner>
</identifier>
</name>
<reference value="https://int.api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449308322" />
</other>
</link>
</Patient>
</resource>
</request>
</entry>
<Patient>
</extension>
</identifier>
</assigner>
</identifier>
</name>
</other>
</link>
</Patient>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</Observation>
</resource>
</request>
</entry>
<ServiceRequest>
</coding>
</valueCodeableConcept>
</extension>
</identifier>
</basedOn>
</coding>
</category>
</coding>
</code>
</identifier>
</subject>
</identifier>
</requester>
</identifier>
</performer>
</coding>
</reasonCode>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</specimen>
</note>
</note>
<text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder" />
</note>
</ServiceRequest>
</resource>
</request>
</entry>
<Observation>
</coding>
</category>
</coding>
</code>
</identifier>
</subject>
</coding>
</valueCodeableConcept>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</code>
</component>
</coding>
</code>
</valueQuantity>
</component>
</coding>
</code>
</component>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</subject>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</valueCodeableConcept>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</code>
</component>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</code>
</component>
</Observation>
</resource>
</request>
</entry>
<Procedure>
</coding>
</code>
</identifier>
</subject>
</note>
</Procedure>
</resource>
</request>
</entry>
<Specimen>
</tag>
</meta>
</identifier>
</coding>
</type>
</subject>
</request>
</Specimen>
</resource>
</request>
</entry>
<RelatedPerson>
</identifier>
</assigner>
</identifier>
</identifier>
</patient>
</coding>
</relationship>
</RelatedPerson>
</resource>
</request>
</entry>
</Bundle>