<Observation xmlns="http://hl7.org/fhir">
  <id value="example-histologic-grade" />
  <meta>
    <profile value="https://www.vision-zero-oncology.de/fhir/StructureDefinition/histopathological-grading-who" />
  </meta>
  <status value="final" />
  <category>
    <coding>
      <system value="http://terminology.hl7.org/CodeSystem/observation-category" />
      <code value="laboratory" />
    </coding>
  </category>
  <code>
    <coding>
      <system value="http://loinc.org" />
      <code value="33732-9" />
      <display value="Histology grade [Identifier] in Cancer specimen" />
    </coding>
    <coding>
      <system value="http://snomed.info/sct" />
      <code value="371469007" />
      <display value="Histologic grade of neoplasm (observable entity)" />
    </coding>
  </code>
  <subject>
    <reference value="Patient/ExamplePatient" />
  </subject>
  <effectiveDateTime value="2022-03-07" />
  <valueCodeableConcept>
    <coding>
      <system value="http://snomed.info/sct" />
      <code value="54102005" />
      <display value="G1 grade (finding)" />
    </coding>
  </valueCodeableConcept>
</Observation>