{
  "resourceType": "Bundle",
  "type": "transaction",
  "entry": [
    {
      "fullUrl": "Procedure/temp-genomic-study-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-genomic-study-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicStudy"
          ]
        },
        "identifier": [
          {
            "type": {
              "coding": [
                {
                  "system": "http://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "requester-case-identifier",
                  "display": "Requester Case Identifier"
                }
              ]
            },
            "system": "http://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "F000XXX2"
          },
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "laboratory-case-identifier",
                  "display": "Laboratory Case Identifier"
                }
              ]
            },
            "system": "http://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "sealingeagle"
          }
        ],
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "405824009",
              "display": "Genetic test (Procedure)"
            }
          ]
        },
        "coding": [
          {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "wgs",
            "display": "Whole Genome Sequencing"
          }
        ],
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "http://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust003"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-ext",
            "valueReference": {
              "reference": "Procedure/temp-genomic-study-analysis-1"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicLaboratoryProcessExtension",
            "valueReference": {
              "reference": "Procedure/temp-laboratory-process-1"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Specimen/temp-genomic-study-analysis-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-genomic-study-analysis-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicStudyAnalysis"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "118117001",
              "display": "Gene mutation analysis (procedure)"
            }
          ]
        },
        "performedDateTime": "2024-12-02T07:45:00+00:00",
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "http://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "extension": [
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-specimen",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicStudyAnalysisVersion",
            "valueString": "12.1.1"
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-title",
            "valueString": "RNA-Fusion"
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-regions",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-bed-1"
                }
              },
              {
                "url": "type",
                "valueCode": "BED"
              },
              {
                "url": "description",
                "valueString": "OMIM-AUTO"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-input",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-fastq-1"
                }
              },
              {
                "url": "type",
                "valueCode": "FASTQ"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-input",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-fastq-2"
                }
              },
              {
                "url": "type",
                "valueCode": "FASTQ"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-input",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-fastq-3"
                }
              },
              {
                "url": "type",
                "valueCode": "FASTQ"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-output",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-vcf-1"
                }
              },
              {
                "url": "type",
                "valueCode": "VCF"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-output",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-cram-1"
                }
              },
              {
                "url": "type",
                "valueCode": "CRAM"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-output",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-cram-2"
                }
              },
              {
                "url": "type",
                "valueCode": "CRAM"
              }
            ]
          },
          {
            "url": "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-output",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-cram-3"
                }
              },
              {
                "url": "type",
                "valueCode": "CRAM"
              }
            ]
          },
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaGenomicAnalysisPedigreeExtension",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-ped-1"
                }
              },
              {
                "url": "type",
                "valueCode": "PEDIGREE"
              }
            ]
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "ResourceName/temp-laboratory-process-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-laboratory-process-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaLaboratoryProcess"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "108252007",
              "display": "Laboratory procedure (procedure)"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicLibraryPreperationExtension",
            "valueReference": {
              "reference": "Procedure/temp-library-preparation-1"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingExtension",
            "valueReference": {
              "reference": "Procedure/temp-gene-sequencing-1"
            }
          },
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Procedure/temp-library-preparation-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-library-preparation-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaLibraryPreperation"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "56245008",
              "display": "Specimen preparation (procedure)"
            }
          ]
        },
        "code": {
          "coding": [
            {
              "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
              "code": "Watchmaker-WGS",
              "display": "Watchmaker WGS"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          },
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaPanelName",
            "valueString": "exome 10"
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Procedure/temp-gene-sequencing-1",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-gene-sequencing-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencing"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "117040002",
              "display": "Nucleic acid sequencing (procedure)"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingResult",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-fastq-1"
                }
              },
              {
                "url": "type",
                "valueCode": "FASTQ"
              }
            ]
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingPlatformExtension",
            "valueString": "NovaSeq X"
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingNumberOfReads",
            "valueInteger": 650000000
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Patient/temp-patient-1",
      "resource": {
        "resourceType": "Patient",
        "id": "temp-patient-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaPatientGenomics"
          ]
        },
        "identifier": {
          "use": "temp",
          "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
          "value": "32121"
        },
        "gender": "female"
      },
      "request": {
        "method": "POST",
        "url": "Patient"
      }
    },
    {
      "fullUrl": "Specimen/temp-specimen-1",
      "resource": {
        "resourceType": "Specimen",
        "id": "temp-specimen-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimen"
          ]
        },
        "type": {
          "coding": [
            {
              "system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/specimen-type",
              "code": "RNA",
              "display": "RNA"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "identifier": [
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "requester-sample-identifier",
                  "display": "Requester Sample Identifier"
                }
              ]
            },
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "2023-32121-3"
          },
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "laboratory-sample-identifier",
                  "display": "Laboratory Sample Identifier"
                }
              ]
            },
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "ACC32121A1"
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenSource",
            "valueString": "cerebrospinal fluid"
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Specimen"
      }
    },
    {
      "fullUrl": "ResourceName/temp-laboratory-process-2",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-laboratory-process-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaLaboratoryProcess"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "108252007",
              "display": "Laboratory procedure (procedure)"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-2"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust003"
              },
              "display": "Klinisk Mikrobiologi"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicLibraryPreperationExtension",
            "valueReference": {
              "reference": "Procedure/temp-library-preparation-2"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingExtension",
            "valueReference": {
              "reference": "Procedure/temp-gene-sequencing-2"
            }
          },
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-2"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Procedure/temp-library-preparation-2",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-library-preparation-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaLibraryPreperation"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "56245008",
              "display": "Specimen preparation (procedure)"
            }
          ]
        },
        "code": {
          "coding": [
            {
              "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
              "code": "truseq-wgs",
              "display": "Truseq WGS"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-2"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust003"
              },
              "display": "Klinisk Mikrobiologi"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-2"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Procedure/temp-gene-sequencing-2",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-gene-sequencing-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencing"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "117040002",
              "display": "Nucleic acid sequencing (procedure)"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-2"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Mikrobiologi"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-2"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingResult",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-fastq-2"
                }
              },
              {
                "url": "type",
                "valueCode": "FASTQ"
              }
            ]
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingPlatformExtension",
            "valueString": "PacBio Revio"
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingNumberOfReads",
            "valueInteger": 26500000
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Patient/temp-patient-2",
      "resource": {
        "resourceType": "Patient",
        "id": "temp-patient-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaPatientGenomics"
          ]
        },
        "identifier": {
          "use": "temp",
          "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
          "value": "56789"
        },
        "gender": "female"
      },
      "request": {
        "method": "POST",
        "url": "Patient"
      }
    },
    {
      "fullUrl": "Specimen/temp-specimen-2",
      "resource": {
        "resourceType": "Specimen",
        "id": "temp-specimen-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimen"
          ]
        },
        "type": {
          "coding": [
            {
              "system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/specimen-type",
              "code": "RNA",
              "display": "RNA"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-2"
        },
        "identifier": [
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "requester-sample-identifier",
                  "display": "Requester Sample Identifier"
                }
              ]
            },
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "1202-72629p"
          },
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "laboratory-sample-identifier",
                  "display": "Laboratory Sample Identifier"
                }
              ]
            },
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "ACC56789A2"
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenSource",
            "valueString": "blood"
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Specimen"
      }
    },
    {
      "fullUrl": "ResourceName/temp-laboratory-process-3",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-laboratory-process-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaLaboratoryProcess"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "108252007",
              "display": "Laboratory procedure (procedure)"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-3"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicLibraryPreperationExtension",
            "valueReference": {
              "reference": "Procedure/temp-library-preparation-3"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingExtension",
            "valueReference": {
              "reference": "Procedure/temp-gene-sequencing-3"
            }
          },
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-3"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Procedure/temp-library-preparation-3",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-library-preparation-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaLibraryPreperation"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "56245008",
              "display": "Specimen preparation (procedure)"
            }
          ]
        },
        "code": {
          "coding": [
            {
              "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
              "code": "truseq-wgs",
              "display": "TruSeq WGS"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-3"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-3"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Procedure/temp-gene-sequencing-3",
      "resource": {
        "resourceType": "Procedure",
        "id": "temp-gene-sequencing-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencing"
          ]
        },
        "status": "completed",
        "category": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "117040002",
              "display": "Nucleic acid sequencing (procedure)"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-3"
        },
        "performer": [
          {
            "actor": {
              "display": "GMCK"
            },
            "onBehalfOf": {
              "identifier": {
                "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                "value": "Cust002"
              },
              "display": "Klinisk Genetik"
            }
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver/fhir/StructureDefinition/KarolinskaFocusExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-3"
            }
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingResult",
            "extension": [
              {
                "url": "file",
                "valueReference": {
                  "reference": "DocumentReference/temp-fastq-3"
                }
              },
              {
                "url": "type",
                "valueCode": "FASTQ"
              }
            ]
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingPlatformExtension",
            "valueString": "Oxford Nanopore Promethion"
          },
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGeneSequencingNumberOfReads",
            "valueInteger": 350000000
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Procedure"
      }
    },
    {
      "fullUrl": "Patient/temp-patient-3",
      "resource": {
        "resourceType": "Patient",
        "id": "temp-patient-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaPatientGenomics"
          ]
        },
        "identifier": {
          "use": "temp",
          "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
          "value": "45656"
        },
        "gender": "male"
      },
      "request": {
        "method": "POST",
        "url": "Patient"
      }
    },
    {
      "fullUrl": "Specimen/temp-specimen-3",
      "resource": {
        "resourceType": "Specimen",
        "id": "temp-specimen-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimen"
          ]
        },
        "type": {
          "coding": [
            {
              "system": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/specimen-type",
              "code": "RNA",
              "display": "RNA"
            }
          ]
        },
        "subject": {
          "reference": "Patient/temp-patient-3"
        },
        "identifier": [
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "requester-sample-identifier",
                  "display": "Requester Sample Identifier"
                }
              ]
            },
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "op-123"
          },
          {
            "type": {
              "coding": [
                {
                  "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
                  "code": "laboratory-sample-identifier",
                  "display": "Laboratory Sample Identifier"
                }
              ]
            },
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "value": "ACC45656A3"
          }
        ],
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenSource",
            "valueString": "blood"
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "Specimen"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-fastq-1",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-fastq-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "fastq",
            "display": "FASTQ"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][FASTQ]",
              "size": 58970,
              "title": "fastq1-exampleName-sampleID-filetype",
              "creation": "2024-11-20T12:00:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-cram-1",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-cram-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "cram",
            "display": "CRAM"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][cram]",
              "size": 500,
              "title": "CRAM1-exampleName-sampleID-filetype",
              "creation": "2024-11-20T12:00:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-ped-1",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-ped-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "ped",
            "display": "PEDIGREE"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][PED]",
              "size": 8450,
              "title": "PED1-exampleName-sampleID-filetype",
              "creation": "2024-11-20T12:00:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-vcf-1",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-vcf-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "vcf",
            "display": "VCF"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][VCF]",
              "size": 25277,
              "title": "VCF1-exampleName-sampleID-filetype",
              "creation": "2024-11-20T12:00:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-bed-1",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-bed-1",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "bed",
            "display": "BED"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-1"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-1"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][BED]",
              "size": 5000,
              "title": "BED1-exampleName-sampleID-filetype",
              "creation": "2024-11-20T12:00:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-fastq-2",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-fastq-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "fastq",
            "display": "FASTQ"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-2"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-2"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][FASTQ]",
              "size": 43620,
              "title": "fastq2-exampleName-sampleID-filetype",
              "creation": "2025-01-20T12:00:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-fastq-3",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-fastq-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "fastq",
            "display": "FASTQ"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-3"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-3"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][FASTQ]",
              "size": 71170,
              "title": "fastq3-exampleName-sampleID-filetype",
              "creation": "2025-01-19T08:35:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-cram-2",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-cram-2",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "cram",
            "display": "CRAM"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-2"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-2"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][cram]",
              "size": 39223,
              "title": "CRAM2-exampleName-sampleID-filetype",
              "creation": "2025-02-21T07:11:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    },
    {
      "fullUrl": "DocumentReference/temp-cram-3",
      "resource": {
        "resourceType": "DocumentReference",
        "id": "temp-cram-3",
        "meta": {
          "profile": [
            "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaGenomicDataFile"
          ]
        },
        "status": "current",
        "type": {
          "coding": {
            "system": "https://ExampleKarolinskaBaseURL/unspecified-system",
            "code": "cram",
            "display": "CRAM"
          }
        },
        "subject": {
          "reference": "Patient/temp-patient-3"
        },
        "extension": [
          {
            "url": "https://karolinskafhirserver.org/fhir/StructureDefinition/KarolinskaSpecimenExtension",
            "valueReference": {
              "reference": "Specimen/temp-specimen-3"
            }
          }
        ],
        "content": [
          {
            "attachment": {
              "url": "https://databaseName[example-specimen][cram]",
              "size": 53761,
              "title": "CRAM3-exampleName-sampleID-filetype",
              "creation": "2025-01-20T11:15:00+00:00"
            }
          }
        ]
      },
      "request": {
        "method": "POST",
        "url": "DocumentReference"
      }
    }
  ]
}