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{
 "resourceType": "StructureDefinition",
 "id": "ext-R4-SubstanceProtein",
 "text": {
 "status": "extensions",
 "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\">Generated Narrative: StructureDefinition ext-R4-SubstanceProtein<a name=\"ext-R4-SubstanceProtein\"> </a><a name=\"hcext-R4-SubstanceProtein\"> </a><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Minimum and Maximum # of times the element can appear in the instance\">Card.</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px; width: 100px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom: 3px\" class=\"hierarchy\"><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Additional information about the element\">Description &amp; Constraints</a><a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/></a></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension\" title=\"This cross-version extension represents SubstanceProtein from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">Extension</a><a name=\"Extension\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension(4.3.0)</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A SubstanceProtein is defined as a single unit of a linear amino acid sequence, or a combination of subunits that are either covalently linked or have a defined invariant stoichiometric relationship. This includes all synthetic, recombinant and purified SubstanceProteins of defined sequence, whether the use is therapeutic or prophylactic. This set of elements will be used to describe albumins, coagulation factors, cytokines, growth factors, peptide/SubstanceProtein hormones, enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck13.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <a style=\"font-style: italic; font-style: italic\" href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension\">Slices for extension</a><a name=\"Extension.extension\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; font-style: italic; opacity: 0.5; font-style: italic\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Extension Slice: Unordered, Closed by value:url </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck135.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:sequenceType\" title=\"Slice sequenceType: This cross-version extension represents SubstanceProtein.sequenceType from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:sequenceType</a><a name=\"Extension.extension.2\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:sequenceType.url\">url</a><a name=\"Extension.extension.url\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;sequenceType&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:sequenceType.value[x]\" title=\"This cross-version extension represents SubstanceProtein.sequenceType from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck135.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:numberOfSubunits\" title=\"Slice numberOfSubunits: This cross-version extension represents SubstanceProtein.numberOfSubunits from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:numberOfSubunits</a><a name=\"Extension.extension.3\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:numberOfSubunits.url\">url</a><a name=\"Extension.extension.url.2\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;numberOfSubunits&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:numberOfSubunits.value[x]\" title=\"This cross-version extension represents SubstanceProtein.numberOfSubunits from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.value_x_.2\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck135.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:disulfideLinkage\" title=\"Slice disulfideLinkage: This cross-version extension represents SubstanceProtein.disulfideLinkage from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:disulfideLinkage</a><a name=\"Extension.extension.4\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:disulfideLinkage.url\">url</a><a name=\"Extension.extension.url.3\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;disulfideLinkage&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:disulfideLinkage.value[x]\" title=\"This cross-version extension represents SubstanceProtein.disulfideLinkage from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.value_x_.3\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit\" title=\"Slice subunit: This cross-version extension represents SubstanceProtein.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:subunit</a><a name=\"Extension.extension.5\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">This subclause refers to the description of each subunit constituting the SubstanceProtein. A subunit is a linear sequence of amino acids linked through peptide bonds. The Subunit information shall be provided when the finished SubstanceProtein is a complex of multiple sequences; subunits are not used to delineate domains within a single sequence. Subunits are listed in order of decreasing length; sequences of the same length will be ordered by decreasing molecular weight; subunits that have identical sequences will be repeated multiple times </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1253.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Definition\" class=\"hierarchy\"/> <a style=\"font-style: italic; font-style: italic\" href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension\">Slices for extension</a><a name=\"Extension.extension.extension\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; font-style: italic; opacity: 0.5; font-style: italic\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Extension Slice: Unordered, Closed by value:url </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:subunit\" title=\"Slice subunit: This cross-version extension represents SubstanceProtein.subunit.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:subunit</a><a name=\"Extension.extension.extension.2\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:subunit.url\">url</a><a name=\"Extension.extension.extension.url\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;subunit&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:subunit.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:sequence\" title=\"Slice sequence: This cross-version extension represents SubstanceProtein.subunit.sequence from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:sequence</a><a name=\"Extension.extension.extension.3\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:sequence.url\">url</a><a name=\"Extension.extension.extension.url.2\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;sequence&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:sequence.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.sequence from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.2\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:length\" title=\"Slice length: This cross-version extension represents SubstanceProtein.subunit.length from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:length</a><a name=\"Extension.extension.extension.4\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Length of linear sequences of amino acids contained in the subunit </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:length.url\">url</a><a name=\"Extension.extension.extension.url.3\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;length&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:length.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.length from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.3\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#integer\">integer</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Length of linear sequences of amino acids contained in the subunit</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:sequenceAttachment\" title=\"Slice sequenceAttachment: This cross-version extension represents SubstanceProtein.subunit.sequenceAttachment from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:sequenceAttachment</a><a name=\"Extension.extension.extension.5\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:sequenceAttachment.url\">url</a><a name=\"Extension.extension.extension.url.4\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;sequenceAttachment&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:sequenceAttachment.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.sequenceAttachment from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.4\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#Attachment\">Attachment</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:nTerminalModificationId\" title=\"Slice nTerminalModificationId: This cross-version extension represents SubstanceProtein.subunit.nTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:nTerminalModificationId</a><a name=\"Extension.extension.extension.6\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:nTerminalModificationId.url\">url</a><a name=\"Extension.extension.extension.url.5\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;nTerminalModificationId&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:nTerminalModificationId.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.nTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.5\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#Identifier\">Identifier</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:nTerminalModification\" title=\"Slice nTerminalModification: This cross-version extension represents SubstanceProtein.subunit.nTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:nTerminalModification</a><a name=\"Extension.extension.extension.7\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:nTerminalModification.url\">url</a><a name=\"Extension.extension.extension.url.6\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;nTerminalModification&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:nTerminalModification.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.nTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.6\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12535.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:cTerminalModificationId\" title=\"Slice cTerminalModificationId: This cross-version extension represents SubstanceProtein.subunit.cTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:cTerminalModificationId</a><a name=\"Extension.extension.extension.8\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125350.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:cTerminalModificationId.url\">url</a><a name=\"Extension.extension.extension.url.7\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;cTerminalModificationId&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125340.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:cTerminalModificationId.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.cTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.7\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#Identifier\">Identifier</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck12525.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slicer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:cTerminalModification\" title=\"Slice cTerminalModification: This cross-version extension represents SubstanceProtein.subunit.cTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">extension:cTerminalModification</a><a name=\"Extension.extension.extension.9\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/extensibility.html#Extension\">Extension</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The modification at the C-terminal shall be specified </td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125250.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:cTerminalModification.url\">url</a><a name=\"Extension.extension.extension.url.8\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;cTerminalModification&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck125240.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.extension:cTerminalModification.value[x]\" title=\"This cross-version extension represents SubstanceProtein.subunit.cTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.\">value[x]</a><a name=\"Extension.extension.extension.value_x_.8\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4B/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">The modification at the C-terminal shall be specified</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1240.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.extension:subunit.url\">url</a><a name=\"Extension.extension.url.4\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;subunit&quot;</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck00.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-ext-R4-SubstanceProtein-definitions.html#Extension.url\">url</a><a name=\"Extension.url\"> </a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5; opacity: 0.5\" href=\"http://hl7.org/fhir/R4B/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : var(--ig-left,left); background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">&quot;http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein&quot;</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"> <a href=\"https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
 },
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
 "valueCode": "fhir"
 },
 {
 "extension": [
 {
 "url": "packageId",
 "valueId": "hl7.fhir.uv.xver-r4.r4b"
 },
 {
 "url": "version",
 "valueString": "0.0.1-snapshot-2"
 }
 ],
 "url": "http://hl7.org/fhir/StructureDefinition/package-source"
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
 "valueInteger": 0,
 "_valueInteger": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
 "valueCanonical": "http://hl7.org/fhir/4.0/ImplementationGuide/hl7.fhir.uv.xver-r4.r4b"
 }
 ]
 }
 },
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
 "valueCode": "trial-use",
 "_valueCode": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
 "valueCanonical": "http://hl7.org/fhir/4.0/ImplementationGuide/hl7.fhir.uv.xver-r4.r4b"
 }
 ]
 }
 }
 ],
 "url": "http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein",
 "version": "0.0.1-snapshot-2",
 "name": "Ext_R4_SubstanceProtein",
 "title": "Cross-version Extension for R4.SubstanceProtein for use in FHIR R4B",
 "status": "active",
 "experimental": false,
 "date": "2025-09-01T12:36:34.31088+00:00",
 "publisher": "FHIR Infrastructure",
 "contact": [
 {
 "name": "FHIR Infrastructure",
 "telecom": [
 {
 "system": "url",
 "value": "http://www.hl7.org/Special/committees/fiwg"
 }
 ]
 }
 ],
 "description": "This cross-version extension represents SubstanceProtein from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "jurisdiction": [
 {
 "coding": [
 {
 "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
 "code": "001",
 "display": "World"
 }
 ]
 }
 ],
 "fhirVersion": "4.3.0",
 "mapping": [
 {
 "identity": "rim",
 "uri": "http://hl7.org/v3",
 "name": "RIM Mapping"
 }
 ],
 "kind": "complex-type",
 "abstract": false,
 "context": [
 {
 "type": "element",
 "expression": "Basic"
 }
 ],
 "type": "Extension",
 "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0",
 "derivation": "constraint",
 "snapshot": {
 "extension": [
 {
 "url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
 "valueString": "4.3.0"
 }
 ],
 "element": [
 {
 "id": "Extension",
 "path": "Extension",
 "short": "A SubstanceProtein is defined as a single unit of a linear amino acid sequence, or a combination of subunits that are either covalently linked or have a defined invariant stoichiometric relationship. This includes all synthetic, recombinant and purified SubstanceProteins of defined sequence, whether the use is therapeutic or prophylactic. This set of elements will be used to describe albumins, coagulation factors, cytokines, growth factors, peptide/SubstanceProtein hormones, enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators",
 "definition": "This cross-version extension represents SubstanceProtein from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Extension",
 "min": 0,
 "max": "*"
 },
 "condition": [
 "ele-1"
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children unless an empty Parameters resource",
 "expression": "hasValue() or (children().count() > id.count()) or $this is Parameters",
 "xpath": "@value|f:*|h:div|self::f:Parameters",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false
 },
 {
 "id": "Extension.id",
 "path": "Extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension",
 "path": "Extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "ordered": false,
 "rules": "closed"
 },
 "short": "Extension",
 "definition": "An Extension",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:sequenceType",
 "path": "Extension.extension",
 "sliceName": "sequenceType",
 "short": "The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence",
 "definition": "This cross-version extension represents SubstanceProtein.sequenceType from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:sequenceType.id",
 "path": "Extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:sequenceType.extension",
 "path": "Extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:sequenceType.url",
 "path": "Extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "sequenceType",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:sequenceType.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence",
 "definition": "This cross-version extension represents SubstanceProtein.sequenceType from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:numberOfSubunits",
 "path": "Extension.extension",
 "sliceName": "numberOfSubunits",
 "short": "Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable",
 "definition": "This cross-version extension represents SubstanceProtein.numberOfSubunits from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:numberOfSubunits.id",
 "path": "Extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:numberOfSubunits.extension",
 "path": "Extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:numberOfSubunits.url",
 "path": "Extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "numberOfSubunits",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:numberOfSubunits.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable",
 "definition": "This cross-version extension represents SubstanceProtein.numberOfSubunits from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:disulfideLinkage",
 "path": "Extension.extension",
 "sliceName": "disulfideLinkage",
 "short": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions",
 "definition": "This cross-version extension represents SubstanceProtein.disulfideLinkage from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:disulfideLinkage.id",
 "path": "Extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:disulfideLinkage.extension",
 "path": "Extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:disulfideLinkage.url",
 "path": "Extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "disulfideLinkage",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:disulfideLinkage.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions",
 "definition": "This cross-version extension represents SubstanceProtein.disulfideLinkage from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit",
 "path": "Extension.extension",
 "sliceName": "subunit",
 "short": "This subclause refers to the description of each subunit constituting the SubstanceProtein. A subunit is a linear sequence of amino acids linked through peptide bonds. The Subunit information shall be provided when the finished SubstanceProtein is a complex of multiple sequences; subunits are not used to delineate domains within a single sequence. Subunits are listed in order of decreasing length; sequences of the same length will be ordered by decreasing molecular weight; subunits that have identical sequences will be repeated multiple times",
 "definition": "This cross-version extension represents SubstanceProtein.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.id",
 "path": "Extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension",
 "path": "Extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "ordered": false,
 "rules": "closed"
 },
 "short": "Extension",
 "definition": "An Extension",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:subunit",
 "path": "Extension.extension.extension",
 "sliceName": "subunit",
 "short": "Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:subunit.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:subunit.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:subunit.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "subunit",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:subunit.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequence",
 "path": "Extension.extension.extension",
 "sliceName": "sequence",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequence from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:sequence.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequence.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequence.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "sequence",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequence.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequence from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:length",
 "path": "Extension.extension.extension",
 "sliceName": "length",
 "short": "Length of linear sequences of amino acids contained in the subunit",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.length from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:length.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:length.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:length.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "length",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:length.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Length of linear sequences of amino acids contained in the subunit",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.length from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment",
 "path": "Extension.extension.extension",
 "sliceName": "sequenceAttachment",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequenceAttachment from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "sequenceAttachment",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequenceAttachment from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Attachment"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId",
 "path": "Extension.extension.extension",
 "sliceName": "nTerminalModificationId",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "nTerminalModificationId",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Identifier"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification",
 "path": "Extension.extension.extension",
 "sliceName": "nTerminalModification",
 "short": "The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "nTerminalModification",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId",
 "path": "Extension.extension.extension",
 "sliceName": "cTerminalModificationId",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "cTerminalModificationId",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Identifier"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification",
 "path": "Extension.extension.extension",
 "sliceName": "cTerminalModification",
 "short": "The modification at the C-terminal shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification.id",
 "path": "Extension.extension.extension.id",
 "representation": [
 "xmlAttr"
 ],
 "short": "Unique id for inter-element referencing",
 "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Element.id",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "id"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification.extension",
 "path": "Extension.extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "description": "Extensions are always sliced by (at least) url",
 "rules": "open"
 },
 "short": "Additional content defined by implementations",
 "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
 "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
 "alias": [
 "extensions",
 "user content"
 ],
 "min": 0,
 "max": "*",
 "base": {
 "path": "Element.extension",
 "min": 0,
 "max": "*"
 },
 "type": [
 {
 "code": "Extension"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 },
 {
 "key": "ext-1",
 "severity": "error",
 "human": "Must have either extensions or value[x], not both",
 "expression": "extension.exists() != value.exists()",
 "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
 "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "n/a"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification.url",
 "path": "Extension.extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "cTerminalModification",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The modification at the C-terminal shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.url",
 "path": "Extension.extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "subunit",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "Value of extension",
 "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4B/extensibility.html) for a list).",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "base64Binary"
 },
 {
 "code": "boolean"
 },
 {
 "code": "canonical"
 },
 {
 "code": "code"
 },
 {
 "code": "date"
 },
 {
 "code": "dateTime"
 },
 {
 "code": "decimal"
 },
 {
 "code": "id"
 },
 {
 "code": "instant"
 },
 {
 "code": "integer"
 },
 {
 "code": "markdown"
 },
 {
 "code": "oid"
 },
 {
 "code": "positiveInt"
 },
 {
 "code": "string"
 },
 {
 "code": "time"
 },
 {
 "code": "unsignedInt"
 },
 {
 "code": "uri"
 },
 {
 "code": "url"
 },
 {
 "code": "uuid"
 },
 {
 "code": "Address"
 },
 {
 "code": "Age"
 },
 {
 "code": "Annotation"
 },
 {
 "code": "Attachment"
 },
 {
 "code": "CodeableConcept"
 },
 {
 "code": "CodeableReference"
 },
 {
 "code": "Coding"
 },
 {
 "code": "ContactPoint"
 },
 {
 "code": "Count"
 },
 {
 "code": "Distance"
 },
 {
 "code": "Duration"
 },
 {
 "code": "HumanName"
 },
 {
 "code": "Identifier"
 },
 {
 "code": "Money"
 },
 {
 "code": "Period"
 },
 {
 "code": "Quantity"
 },
 {
 "code": "Range"
 },
 {
 "code": "Ratio"
 },
 {
 "code": "RatioRange"
 },
 {
 "code": "Reference"
 },
 {
 "code": "SampledData"
 },
 {
 "code": "Signature"
 },
 {
 "code": "Timing"
 },
 {
 "code": "ContactDetail"
 },
 {
 "code": "Contributor"
 },
 {
 "code": "DataRequirement"
 },
 {
 "code": "Expression"
 },
 {
 "code": "ParameterDefinition"
 },
 {
 "code": "RelatedArtifact"
 },
 {
 "code": "TriggerDefinition"
 },
 {
 "code": "UsageContext"
 },
 {
 "code": "Dosage"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.url",
 "path": "Extension.url",
 "representation": [
 "xmlAttr"
 ],
 "short": "identifies the meaning of the extension",
 "definition": "Source of the definition for the extension code - a logical name or a URL.",
 "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "type": [
 {
 "extension": [
 {
 "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
 "valueUrl": "uri"
 }
 ],
 "code": "http://hl7.org/fhirpath/System.String"
 }
 ],
 "fixedUri": "http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein",
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 },
 {
 "id": "Extension.value[x]",
 "path": "Extension.value[x]",
 "short": "Value of extension",
 "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4B/extensibility.html) for a list).",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "base64Binary"
 },
 {
 "code": "boolean"
 },
 {
 "code": "canonical"
 },
 {
 "code": "code"
 },
 {
 "code": "date"
 },
 {
 "code": "dateTime"
 },
 {
 "code": "decimal"
 },
 {
 "code": "id"
 },
 {
 "code": "instant"
 },
 {
 "code": "integer"
 },
 {
 "code": "markdown"
 },
 {
 "code": "oid"
 },
 {
 "code": "positiveInt"
 },
 {
 "code": "string"
 },
 {
 "code": "time"
 },
 {
 "code": "unsignedInt"
 },
 {
 "code": "uri"
 },
 {
 "code": "url"
 },
 {
 "code": "uuid"
 },
 {
 "code": "Address"
 },
 {
 "code": "Age"
 },
 {
 "code": "Annotation"
 },
 {
 "code": "Attachment"
 },
 {
 "code": "CodeableConcept"
 },
 {
 "code": "CodeableReference"
 },
 {
 "code": "Coding"
 },
 {
 "code": "ContactPoint"
 },
 {
 "code": "Count"
 },
 {
 "code": "Distance"
 },
 {
 "code": "Duration"
 },
 {
 "code": "HumanName"
 },
 {
 "code": "Identifier"
 },
 {
 "code": "Money"
 },
 {
 "code": "Period"
 },
 {
 "code": "Quantity"
 },
 {
 "code": "Range"
 },
 {
 "code": "Ratio"
 },
 {
 "code": "RatioRange"
 },
 {
 "code": "Reference"
 },
 {
 "code": "SampledData"
 },
 {
 "code": "Signature"
 },
 {
 "code": "Timing"
 },
 {
 "code": "ContactDetail"
 },
 {
 "code": "Contributor"
 },
 {
 "code": "DataRequirement"
 },
 {
 "code": "Expression"
 },
 {
 "code": "ParameterDefinition"
 },
 {
 "code": "RelatedArtifact"
 },
 {
 "code": "TriggerDefinition"
 },
 {
 "code": "UsageContext"
 },
 {
 "code": "Dosage"
 }
 ],
 "constraint": [
 {
 "key": "ele-1",
 "severity": "error",
 "human": "All FHIR elements must have a @value or children",
 "expression": "hasValue() or (children().count() > id.count())",
 "xpath": "@value|f:*|h:div",
 "source": "http://hl7.org/fhir/StructureDefinition/Element|4.3.0"
 }
 ],
 "isModifier": false,
 "isSummary": false,
 "mapping": [
 {
 "identity": "rim",
 "map": "N/A"
 }
 ]
 }
 ]
 },
 "differential": {
 "element": [
 {
 "id": "Extension",
 "path": "Extension",
 "short": "A SubstanceProtein is defined as a single unit of a linear amino acid sequence, or a combination of subunits that are either covalently linked or have a defined invariant stoichiometric relationship. This includes all synthetic, recombinant and purified SubstanceProteins of defined sequence, whether the use is therapeutic or prophylactic. This set of elements will be used to describe albumins, coagulation factors, cytokines, growth factors, peptide/SubstanceProtein hormones, enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators",
 "definition": "This cross-version extension represents SubstanceProtein from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension",
 "path": "Extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "ordered": false,
 "rules": "closed"
 },
 "min": 0,
 "max": "*",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:sequenceType",
 "path": "Extension.extension",
 "sliceName": "sequenceType",
 "short": "The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence",
 "definition": "This cross-version extension represents SubstanceProtein.sequenceType from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:sequenceType.url",
 "path": "Extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "sequenceType"
 },
 {
 "id": "Extension.extension:sequenceType.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence",
 "definition": "This cross-version extension represents SubstanceProtein.sequenceType from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "CodeableConcept"
 }
 ]
 },
 {
 "id": "Extension.extension:numberOfSubunits",
 "path": "Extension.extension",
 "sliceName": "numberOfSubunits",
 "short": "Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable",
 "definition": "This cross-version extension represents SubstanceProtein.numberOfSubunits from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:numberOfSubunits.url",
 "path": "Extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "numberOfSubunits"
 },
 {
 "id": "Extension.extension:numberOfSubunits.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable",
 "definition": "This cross-version extension represents SubstanceProtein.numberOfSubunits from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ]
 },
 {
 "id": "Extension.extension:disulfideLinkage",
 "path": "Extension.extension",
 "sliceName": "disulfideLinkage",
 "short": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions",
 "definition": "This cross-version extension represents SubstanceProtein.disulfideLinkage from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:disulfideLinkage.url",
 "path": "Extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "disulfideLinkage"
 },
 {
 "id": "Extension.extension:disulfideLinkage.value[x]",
 "path": "Extension.extension.value[x]",
 "short": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions",
 "definition": "This cross-version extension represents SubstanceProtein.disulfideLinkage from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit",
 "path": "Extension.extension",
 "sliceName": "subunit",
 "short": "This subclause refers to the description of each subunit constituting the SubstanceProtein. A subunit is a linear sequence of amino acids linked through peptide bonds. The Subunit information shall be provided when the finished SubstanceProtein is a complex of multiple sequences; subunits are not used to delineate domains within a single sequence. Subunits are listed in order of decreasing length; sequences of the same length will be ordered by decreasing molecular weight; subunits that have identical sequences will be repeated multiple times",
 "definition": "This cross-version extension represents SubstanceProtein.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "*",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension",
 "path": "Extension.extension.extension",
 "slicing": {
 "discriminator": [
 {
 "type": "value",
 "path": "url"
 }
 ],
 "ordered": false,
 "rules": "closed"
 },
 "min": 0,
 "max": "*",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:subunit",
 "path": "Extension.extension.extension",
 "sliceName": "subunit",
 "short": "Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:subunit.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "subunit"
 },
 {
 "id": "Extension.extension:subunit.extension:subunit.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.subunit from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequence",
 "path": "Extension.extension.extension",
 "sliceName": "sequence",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequence from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:sequence.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "sequence"
 },
 {
 "id": "Extension.extension:subunit.extension:sequence.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequence from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:length",
 "path": "Extension.extension.extension",
 "sliceName": "length",
 "short": "Length of linear sequences of amino acids contained in the subunit",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.length from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:length.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "length"
 },
 {
 "id": "Extension.extension:subunit.extension:length.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Length of linear sequences of amino acids contained in the subunit",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.length from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "integer"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment",
 "path": "Extension.extension.extension",
 "sliceName": "sequenceAttachment",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequenceAttachment from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "sequenceAttachment"
 },
 {
 "id": "Extension.extension:subunit.extension:sequenceAttachment.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.sequenceAttachment from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Attachment"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId",
 "path": "Extension.extension.extension",
 "sliceName": "nTerminalModificationId",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "nTerminalModificationId"
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModificationId.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Identifier"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification",
 "path": "Extension.extension.extension",
 "sliceName": "nTerminalModification",
 "short": "The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "nTerminalModification"
 },
 {
 "id": "Extension.extension:subunit.extension:nTerminalModification.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.nTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId",
 "path": "Extension.extension.extension",
 "sliceName": "cTerminalModificationId",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "cTerminalModificationId"
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModificationId.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModificationId from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "Identifier"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification",
 "path": "Extension.extension.extension",
 "sliceName": "cTerminalModification",
 "short": "The modification at the C-terminal shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "min": 0,
 "max": "1",
 "base": {
 "path": "Extension.extension",
 "min": 0,
 "max": "*"
 }
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification.url",
 "path": "Extension.extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "cTerminalModification"
 },
 {
 "id": "Extension.extension:subunit.extension:cTerminalModification.value[x]",
 "path": "Extension.extension.extension.value[x]",
 "short": "The modification at the C-terminal shall be specified",
 "definition": "This cross-version extension represents SubstanceProtein.subunit.cTerminalModification from http://hl7.org/fhir/StructureDefinition/SubstanceProtein|4.0.1 for use in FHIR R4B.",
 "base": {
 "path": "Extension.value[x]",
 "min": 0,
 "max": "1"
 },
 "type": [
 {
 "code": "string"
 }
 ]
 },
 {
 "id": "Extension.extension:subunit.url",
 "path": "Extension.extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "subunit"
 },
 {
 "id": "Extension.url",
 "path": "Extension.url",
 "min": 1,
 "max": "1",
 "base": {
 "path": "Extension.url",
 "min": 1,
 "max": "1"
 },
 "fixedUri": "http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein"
 }
 ]
 }
}

name : Ext_R4_SubstanceProtein

{

}