{
  "resourceType": "StructureDefinition",
  "url": "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Condition-PrimaryDiagnosis",
  "version": "0.0.1",
  "name": "PrimaryDiagnosis",
  "title": "Primary Diagnosis",
  "status": "draft",
  "description": "Corresponds to the primary diagnosis. Parameters for classifying the primary disease are recorded. These include ICD-10, ICD-O-3 (topography) and lateral localization. Links to histology (topography) and the TNM classifications (pathological/clinical)",
  "fhirVersion": "4.0.1",
  "kind": "resource",
  "abstract": false,
  "type": "Condition",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Condition",
  "derivation": "constraint",
  "differential": {
    "element": [
      {
        "id": "Condition.extension:specimen",
        "path": "Condition.extension",
        "sliceName": "specimen",
        "alias": [
          "Biosample"
        ],
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Extension-Specimen"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Condition.code",
        "path": "Condition.code",
        "short": "Code of the primary diagnosis",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding",
        "path": "Condition.code.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "system"
            }
          ],
          "rules": "open"
        }
      },
      {
        "id": "Condition.code.coding:icd10-gm",
        "path": "Condition.code.coding",
        "sliceName": "icd10-gm",
        "short": "Code defined by ICD- system",
        "max": "1",
        "type": [
          {
            "code": "Coding",
            "profile": [
              "http://fhir.de/StructureDefinition/CodingICD10GM"
            ]
          }
        ],
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "valueSet": "http://fhir.de/ValueSet/bfarm/icd-10-gm"
        }
      },
      {
        "id": "Condition.code.coding:icd10-gm.system",
        "path": "Condition.code.coding.system",
        "short": "ICD-10-GM"
      },
      {
        "id": "Condition.code.coding:icd10-gm.version",
        "path": "Condition.code.coding.version",
        "short": "Version of the ICD-10 catalog",
        "definition": "Catalog version of the ICD",
        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "description": "ICD-10-Catalog (Version)",
          "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/ICDVersionVS"
        }
      },
      {
        "id": "Condition.code.coding:icd10-gm.code",
        "path": "Condition.code.coding.code",
        "short": "PrimaryDiagnosis",
        "definition": "Coding of the patient’s disease (diagnosis) based on the current ICD classification",
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding:alpha-id",
        "path": "Condition.code.coding",
        "sliceName": "alpha-id",
        "max": "1",
        "type": [
          {
            "code": "Coding",
            "profile": [
              "http://fhir.de/StructureDefinition/CodingAlphaID"
            ]
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "http://fhir.de/ValueSet/bfarm/alpha-id"
        }
      },
      {
        "id": "Condition.code.coding:alpha-id.system",
        "path": "Condition.code.coding.system",
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding:alpha-id.code",
        "path": "Condition.code.coding.code",
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding:sct",
        "path": "Condition.code.coding",
        "sliceName": "sct",
        "max": "1",
        "binding": {
          "strength": "required",
          "valueSet": "https://www.medizininformatik-initiative.de/fhir/core/modul-diagnose/ValueSet/diagnoses-sct"
        }
      },
      {
        "id": "Condition.code.coding:sct.system",
        "path": "Condition.code.coding.system",
        "min": 1,
        "fixedUri": "http://snomed.info/sct",
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding:sct.code",
        "path": "Condition.code.coding.code",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding:orphanet",
        "path": "Condition.code.coding",
        "sliceName": "orphanet",
        "max": "1"
      },
      {
        "id": "Condition.code.coding:orphanet.system",
        "path": "Condition.code.coding.system",
        "min": 1,
        "fixedUri": "http://www.orpha.net",
        "mustSupport": true
      },
      {
        "id": "Condition.code.coding:orphanet.code",
        "path": "Condition.code.coding.code",
        "min": 1
      },
      {
        "id": "Condition.code.text",
        "path": "Condition.code.text",
        "short": "Primary tumor diagnosis text",
        "definition": "Description of a disease as free text",
        "mustSupport": true
      },
      {
        "id": "Condition.bodySite",
        "path": "Condition.bodySite",
        "mustSupport": true
      },
      {
        "id": "Condition.bodySite.coding",
        "path": "Condition.bodySite.coding",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "system"
            }
          ],
          "rules": "open"
        },
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Condition.bodySite.coding:ICD-O-3-T",
        "path": "Condition.bodySite.coding",
        "sliceName": "ICD-O-3-T",
        "short": "ICD O-3 Topography",
        "max": "1",
        "mustSupport": true
      },
      {
        "id": "Condition.bodySite.coding:ICD-O-3-T.system",
        "path": "Condition.bodySite.coding.system",
        "short": "ICD-O-3",
        "min": 1,
        "fixedUri": "urn:oid:2.16.840.1.113883.6.43.1"
      },
      {
        "id": "Condition.bodySite.coding:ICD-O-3-T.version",
        "path": "Condition.bodySite.coding.version",
        "short": "ICD-O catalog topography (version)",
        "definition": "Catalogue version of ICD-O",
        "min": 1,
        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "description": "ICD-O-3 Version",
          "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/ICDOVersionVS"
        }
      },
      {
        "id": "Condition.bodySite.coding:ICD-O-3-T.code",
        "path": "Condition.bodySite.coding.code",
        "short": "Localization",
        "definition": "Designation of the topography of a disease based on the current ICD-O-3 classification",
        "min": 1,
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "description": "ICD-O-3 Topography",
          "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/TopographyICDO3VS"
        }
      },
      {
        "id": "Condition.bodySite.coding:TumorSiteLocation",
        "path": "Condition.bodySite.coding",
        "sliceName": "TumorSiteLocation",
        "max": "1",
        "mustSupport": true,
        "binding": {
          "strength": "required",
          "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/TumorSiteLocationVS"
        }
      },
      {
        "id": "Condition.bodySite.coding:TumorSiteLocation.system",
        "path": "Condition.bodySite.coding.system",
        "min": 1,
        "fixedUri": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/TumorSiteLocationCS"
      },
      {
        "id": "Condition.bodySite.coding:TumorSiteLocation.code",
        "path": "Condition.bodySite.coding.code",
        "short": "Site location",
        "definition": "Organ-specific information of the affected side",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Condition.subject",
        "path": "Condition.subject",
        "short": "Patient who has the condition",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Patient-Patient",
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Patient-Pseudonym"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Condition.subject.reference",
        "path": "Condition.subject.reference",
        "min": 1,
        "mustSupport": true
      },
      {
        "id": "Condition.onset[x]",
        "path": "Condition.onset[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "ordered": false,
          "rules": "open"
        },
        "mustSupport": true
      },
      {
        "id": "Condition.onset[x]:onsetDateTime",
        "path": "Condition.onset[x]",
        "sliceName": "onsetDateTime",
        "short": "Tumor Diagnosisdate",
        "definition": "The date on which the reportable diagnosis was first diagnosed clinically or microscopically by a physician",
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Condition.stage.assessment",
        "path": "Condition.stage.assessment",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-TNMp",
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-TNMc"
            ]
          }
        ],
        "mustSupport": true
      },
      {
        "id": "Condition.stage.assessment.reference",
        "path": "Condition.stage.assessment.reference",
        "min": 1
      },
      {
        "id": "Condition.evidence",
        "path": "Condition.evidence",
        "mustSupport": true
      },
      {
        "id": "Condition.evidence.code",
        "path": "Condition.evidence.code",
        "short": "Diagnostic backup",
        "definition": "Highest achieved diagnostic certainty on the date of diagnosis",
        "max": "1",
        "mustSupport": true,
        "binding": {
          "strength": "extensible",
          "description": "Diagnostic backup",
          "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/DiagnosticConfirmationVS"
        }
      },
      {
        "id": "Condition.evidence.code.coding.system",
        "path": "Condition.evidence.code.coding.system",
        "fixedUri": "https://www.cancercoreeurope.eu/fhir/core/CodeSystem/DiagnosticConfirmationCS",
        "mustSupport": true
      },
      {
        "id": "Condition.evidence.code.coding.code",
        "path": "Condition.evidence.code.coding.code",
        "mustSupport": true
      },
      {
        "id": "Condition.evidence.detail",
        "path": "Condition.evidence.detail",
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-Histology",
              "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-GeneticVariant"
            ]
          }
        ]
      },
      {
        "id": "Condition.evidence.detail.reference",
        "path": "Condition.evidence.detail.reference",
        "min": 1
      }
    ]
  }
}