{
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  "id": "CASIDE-CancerTumorMarkers",
  "meta": {
    "lastUpdated": "2021-07-16T08:37:22.833+00:00"
  },
  "url": "http://gradiant.org/fhir/StructureDefinition/CASIDECancerTumorMarkers",
  "version": "1.0",
  "name": "CASIDECancerTumorMarkers",
  "title": "Cancer Tumor Markers Profile",
  "status": "draft",
  "publisher": "GRADIANT",
  "contact": [
    {
      "name": "GRADIANT",
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          "value": "https://www.gradiant.org/",
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        }
      ]
    }
  ],
  "description": "Tumor markers provide information about the cancer, such as the degree of malignancy, whether it is possible to use targeted therapy, or whether the cancer responds to treatment. This profile includes traditional tumor markers that can be found in the blood, urine, stool, tumors, or other tissues or bodily fluids, as well as genomic markers such as tumor gene mutations. It also include novel biomarkers like CTCs (Circulating Tumor Cells) from liquid biopsy, that have demonstrated clinical significance and support therapeutic decisions of the oncologists.",
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  "mapping": [
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      "uri": "http://hl7.org/fhir/workflow",
      "name": "Workflow Pattern"
    },
    {
      "identity": "sct-concept",
      "uri": "http://snomed.info/conceptdomain",
      "name": "SNOMED CT Concept Domain Binding"
    },
    {
      "identity": "v2",
      "uri": "http://hl7.org/v2",
      "name": "HL7 v2 Mapping"
    },
    {
      "identity": "rim",
      "uri": "http://hl7.org/v3",
      "name": "RIM Mapping"
    },
    {
      "identity": "w5",
      "uri": "http://hl7.org/fhir/fivews",
      "name": "FiveWs Pattern Mapping"
    },
    {
      "identity": "sct-attr",
      "uri": "http://snomed.org/attributebinding",
      "name": "SNOMED CT Attribute Binding"
    }
  ],
  "kind": "resource",
  "abstract": false,
  "type": "Observation",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Observation",
  "derivation": "constraint",
  "differential": {
    "element": [
      {
        "id": "Observation.category",
        "path": "Observation.category",
        "min": 1,
        "max": "1",
        "patternCodeableConcept": {
          "coding": [
            {
              "system": "http://terminology.hl7.org/CodeSystem/observation-category",
              "code": "laboratory"
            }
          ]
        }
      },
      {
        "id": "Observation.code",
        "path": "Observation.code",
        "patternCodeableConcept": {
          "coding": [
            {
              "system": "http://loinc.org"
            }
          ]
        },
        "binding": {
          "strength": "extensible",
          "valueSet": "http://gradiant.org/fhir/ValueSet/CASIDECancerTumorMarkerVS"
        }
      },
      {
        "id": "Observation.subject",
        "path": "Observation.subject",
        "min": 1,
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
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          }
        ]
      },
      {
        "id": "Observation.effective[x]",
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        "min": 1,
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            "code": "dateTime"
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      },
      {
        "id": "Observation.value[x]",
        "path": "Observation.value[x]",
        "min": 1,
        "type": [
          {
            "code": "Quantity"
          },
          {
            "code": "CodeableConcept"
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      {
        "id": "Observation.dataAbsentReason",
        "path": "Observation.dataAbsentReason",
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      {
        "id": "Observation.hasMember",
        "path": "Observation.hasMember",
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  }
}