{
  "resourceType": "StructureDefinition",
  "id": "HdBe-AllergyIntolerance",
  "url": "https://fhir.healthdata.be/StructureDefinition/HdBe-AllergyIntolerance",
  "name": "HdBeAllergyIntolerance",
  "title": "HdBe AllergyIntolerance",
  "status": "draft",
  "date": "2022-10-17T09:09:13.9562003+00:00",
  "publisher": "Healthdata.be (Sciensano)",
  "contact": [
    {
      "name": "Service portal – healthdata.be",
      "telecom": [
        {
          "system": "url",
          "value": "https://sciensano.service-now.com/sp",
          "use": "work"
        }
      ]
    }
  ],
  "description": "An allergy or intolerance describes a patient’s tendency towards hypersensitivity to a certain substance, so that an unwanted physiological reaction is expected after exposure to the substance, while most people would not exhibit such a reaction to that amount. The observed physiological changes are usually the result of an immunological reaction.\r\nThe substances can be categorized as follows:\r\n* Medicine\r\n* Medicine category\r\n* Ingredient/addition\r\n* Nutrition\r\n* Environmental factor\r\n* Animal\r\n* Plants\r\n* Chemicals\r\n* Inhaled allergenic",
  "copyright": "Copyright and related rights waived via CC0, https://creativecommons.org/publicdomain/zero/1.0/. This does not apply to information from third parties, for example a medical terminology system. The implementer alone is responsible for identifying and obtaining any necessary licenses or authorizations to utilize third party IP in connection with the specification or otherwise.",
  "fhirVersion": "4.0.1",
  "mapping": [
    {
      "identity": "zib-allergyintolerance-v3.3-2020EN",
      "uri": "https://zibs.nl/wiki/AllergyIntolerance-v3.3(2020EN)",
      "name": "zib AllergyIntolerance-v3.3(2020EN)"
    },
    {
      "identity": "HdBe-AllergyIntolerance",
      "uri": "https://fhir.healthdata.be/StructureDefinition/LogicalModel/HdBe-Patient",
      "name": "HdBe logical model AllergyIntolerance"
    }
  ],
  "kind": "resource",
  "abstract": false,
  "type": "AllergyIntolerance",
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance",
  "derivation": "constraint",
  "snapshot": {
    "element": [
      {
        "id": "AllergyIntolerance",
        "path": "AllergyIntolerance",
        "short": "AllergyIntolerance",
        "definition": "Risk of harmful or undesirable, physiological response which is unique to an individual and associated with exposure to a substance.",
        "comment": "Substances include, but are not limited to: a therapeutic substance administered correctly at an appropriate dosage for the individual; food; material derived from plants or animals; or venom from insect stings.",
        "alias": [
          "Allergy",
          "Intolerance",
          "Adverse Reaction",
          "AllergieIntolerantie"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance",
          "min": 0,
          "max": "*"
        },
        "constraint": [
          {
            "key": "dom-2",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
            "expression": "contained.contained.empty()",
            "xpath": "not(parent::f:contained and f:contained)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-1",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL NOT contain any narrative",
            "expression": "contained.text.empty()",
            "xpath": "not(parent::f:contained and f:text)",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-4",
            "severity": "error",
            "human": "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
            "expression": "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
            "xpath": "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "dom-3",
            "severity": "error",
            "human": "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource",
            "expression": "contained.where(('#'+id in %resource.descendants().reference).not()).empty()",
            "xpath": "not(exists(for $id in f:contained/*/@id return $id[not(ancestor::f:contained/parent::*/descendant::f:reference/@value=concat('#', $id))]))",
            "source": "http://hl7.org/fhir/StructureDefinition/DomainResource"
          },
          {
            "key": "ait-1",
            "severity": "error",
            "human": "AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error.",
            "expression": "verificationStatus='entered-in-error' or clinicalStatus.exists()",
            "xpath": "f:verificationStatus/@value='entered-in-error' or exists(f:clinicalStatus)",
            "source": "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance"
          },
          {
            "key": "ait-2",
            "severity": "error",
            "human": "AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error",
            "expression": "verificationStatus!='entered-in-error' or clinicalStatus.empty()",
            "xpath": "f:verificationStatus/@value!='entered-in-error' or not(exists(f:clinicalStatus))",
            "source": "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "rim",
            "map": "Observation[classCode=OBS, moodCode=EVN]"
          },
          {
            "identity": "w5",
            "map": "clinical.general"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.1",
            "comment": "AllergyIntolerance"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.id",
        "path": "AllergyIntolerance.id",
        "short": "Logical id of this artifact",
        "definition": "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
        "comment": "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "id"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.meta",
        "path": "AllergyIntolerance.meta",
        "short": "Metadata about the resource",
        "definition": "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content may not always be associated with version changes to the resource.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.meta",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Meta"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.implicitRules",
        "path": "AllergyIntolerance.implicitRules",
        "short": "A set of rules under which this content was created",
        "definition": "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content.",
        "comment": "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. \n\nThis element is labelled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.implicitRules",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.language",
        "path": "AllergyIntolerance.language",
        "short": "Language of the resource content",
        "definition": "The base language in which the resource is written.",
        "comment": "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource  Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Resource.language",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
              "valueReference": {
                "reference": "http://hl7.org/fhir/ValueSet/all-languages"
              }
            },
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Language"
            }
          ],
          "strength": "extensible",
          "description": "A human language."
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.text",
        "path": "AllergyIntolerance.text",
        "short": "Text summary of the resource, for human interpretation",
        "definition": "A human-readable narrative that contains a summary of the resource, and may be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
        "comment": "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded in formation is added later.",
        "alias": [
          "narrative",
          "html",
          "xhtml",
          "display"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "DomainResource.text",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Narrative"
          }
        ],
        "condition": [
          "ele-1",
          "dom-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act.text?"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.contained",
        "path": "AllergyIntolerance.contained",
        "short": "Contained, inline Resources",
        "definition": "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
        "comment": "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again.",
        "alias": [
          "inline resources",
          "anonymous resources",
          "contained resources"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.contained",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Resource"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "Entity. Role, or Act"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.extension",
        "path": "AllergyIntolerance.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.modifierExtension",
        "path": "AllergyIntolerance.modifierExtension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Extensions that cannot be ignored",
        "definition": "May be used to represent additional information that is not part of the basic definition of the resource, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "DomainResource.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.identifier",
        "path": "AllergyIntolerance.identifier",
        "short": "External ids for this item",
        "definition": "This records identifiers associated with this allergy/intolerance concern that are defined by business processes and/or used to refer to it when a direct URL reference to the resource itself is not appropriate (e.g. in CDA documents, or in written / printed documentation).",
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.identifier",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Identifier"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CX / EI (occasionally, more often EI maps to a resource id or a URL)"
          },
          {
            "identity": "rim",
            "map": "II - see see identifier pattern at http://wiki.hl7.org/index.php?title=Common_Design_Patterns#Identifier_Pattern for relevant discussion. The Identifier class is a little looser than the v3 type II because it allows URIs as well as registered OIDs or GUIDs.  Also maps to Role[classCode=IDENT]"
          },
          {
            "identity": "servd",
            "map": "Identifier"
          },
          {
            "identity": "v2",
            "map": "IAM-7"
          },
          {
            "identity": "rim",
            "map": "id"
          },
          {
            "identity": "w5",
            "map": "id"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.clinicalStatus",
        "path": "AllergyIntolerance.clinicalStatus",
        "short": "AllergyStatus",
        "definition": "Statement on the status of the patient’s hypersensitivity.",
        "comment": "See the comment on the root element for guidance on mapping zib AllergyStatus to FHIR.",
        "alias": [
          "AllergieStatus"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.clinicalStatus",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1",
          "ait-1",
          "ait-2"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceClinicalStatus"
            }
          ],
          "strength": "required",
          "description": "Use ConceptMap AllergyStatusCodelist_to_AllergyIntoleranceClinicalStatusCodes to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceClinicalStatusCodes",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/AllergyStatus-to-AllergyIntoleranceClinicalStatusCodes"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "Observation ACT\n.inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"clinicalStatus\", moodCode=EVN].value"
          },
          {
            "identity": "w5",
            "map": "status"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.5",
            "comment": "AllergyStatus"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.AllergyStatus"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.verificationStatus",
        "path": "AllergyIntolerance.verificationStatus",
        "short": "AllergyStatus",
        "definition": "Assertion about certainty associated with the propensity, or potential risk, of a reaction to the identified substance (including pharmaceutical product).",
        "comment": "This element is labeled as a modifier because the status contains the codes refuted and entered-in-error that mark the AllergyIntolerance as not currently valid.",
        "alias": [
          "AllergieStatus"
        ],
        "min": 1,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.verificationStatus",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1",
          "ait-1",
          "ait-2"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isModifier": true,
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceVerificationStatus"
            }
          ],
          "strength": "required",
          "description": "Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance."
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "Observation ACT\n.inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"verificationStatus\", moodCode=EVN].value"
          },
          {
            "identity": "w5",
            "map": "status"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.5",
            "comment": "AllergyStatus"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.type",
        "path": "AllergyIntolerance.type",
        "short": "allergy | intolerance - Underlying mechanism (if known)",
        "definition": "Identification of the underlying physiological mechanism for the reaction risk.",
        "comment": "Allergic (typically immune-mediated) reactions have been traditionally regarded as an indicator for potential escalation to significant future risk. Contemporary knowledge suggests that some reactions previously thought to be immune-mediated are, in fact, non-immune, but in some cases can still pose a life threatening risk. It is acknowledged that many clinicians may not be in a position to distinguish the mechanism of a particular reaction. Often the term \"allergy\" is used rather generically and may overlap with the use of \"intolerance\" - in practice the boundaries between these two concepts may not be well-defined or understood. This data element is included nevertheless, because many legacy systems have captured this attribute. Immunologic testing may provide supporting evidence for the basis of the reaction and the causative substance, but no tests are 100% sensitive or specific for sensitivity to a particular substance. If, as is commonly the case, it is unclear whether the reaction is due to an allergy or an intolerance, then the type element should be omitted from the resource.",
        "alias": [
          "Category",
          "Class"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.type",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceType"
            }
          ],
          "strength": "required",
          "description": "Identification of the underlying physiological mechanism for a Reaction Risk."
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "IAM-9"
          },
          {
            "identity": "rim",
            "map": "code"
          },
          {
            "identity": "w5",
            "map": "class"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category",
        "path": "AllergyIntolerance.category",
        "short": "AllergyCategory",
        "definition": "Identifies the allergy category such as medication, food or environment.",
        "comment": "This data element has been included because it is currently being captured in some clinical systems. This data can be derived from the substance where coding systems are used, and is effectively redundant in that situation.  When searching on category, consider the implications of AllergyIntolerance resources without a category.  For example, when searching on category = medication, medication allergies that don't have a category valued will not be returned.  Refer to [search](search.html) for more information on how to search category with a :missing modifier to get allergies that don't have a category.  Additionally, category should be used with caution because category can be subjective based on the sender.",
        "alias": [
          "Category",
          "Type",
          "Reaction Type",
          "Class",
          "AllergieCategorie"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.category",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceCategory"
            }
          ],
          "strength": "required",
          "description": "Use ConceptMap AllergyCategoryCodelist_to_AllergyIntoleranceCategory to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceCategory",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/AllergyCategory-to-AllergyIntoleranceCategory"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "AL1-2"
          },
          {
            "identity": "rim",
            "map": "value < IntoleranceValue (Agent)"
          },
          {
            "identity": "w5",
            "map": "class"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.4",
            "comment": "AllergyCategory"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.AllergyCategory"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.id",
        "path": "AllergyIntolerance.category.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "xml:id (or equivalent in JSON)",
        "definition": "unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension",
        "path": "AllergyIntolerance.category.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist",
        "path": "AllergyIntolerance.category.extension",
        "sliceName": "allergyCategoryCodelist",
        "short": "Optional Extensions Element",
        "definition": "Optional Extension Element - found in all resources.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://fhir.healthdata.be/StructureDefinition/ext-CodeSpecification"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist.id",
        "path": "AllergyIntolerance.category.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "xml:id (or equivalent in JSON)",
        "definition": "unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist.extension",
        "path": "AllergyIntolerance.category.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist.url",
        "path": "AllergyIntolerance.category.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "fixedUri": "https://fhir.healthdata.be/StructureDefinition/ext-CodeSpecification",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist.value[x]",
        "path": "AllergyIntolerance.category.extension.value[x]",
        "short": "AllergyCategory",
        "definition": "Identifies the allergy category such as medication, food or environment.",
        "alias": [
          "AllergieCategorie"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/AllergyCategory"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.4",
            "comment": "AllergyCategory"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.AllergyCategory"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.value",
        "path": "AllergyIntolerance.category.value",
        "representation": [
          "xmlAttr"
        ],
        "short": "Primitive value for code",
        "definition": "Primitive value for code",
        "min": 0,
        "max": "1",
        "base": {
          "path": "string.value",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-regex",
                "valueString": "[^\\s]+([\\s]?[^\\s]+)*"
              }
            ],
            "_code": {
              "extension": [
                {
                  "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-json-type",
                  "valueString": "string"
                },
                {
                  "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-xml-type",
                  "valueString": "xsd:token"
                },
                {
                  "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-rdf-type",
                  "valueString": "xsd:token"
                }
              ]
            }
          }
        ],
        "maxLength": 1048576
      },
      {
        "id": "AllergyIntolerance.criticality",
        "path": "AllergyIntolerance.criticality",
        "short": "Criticality",
        "definition": "Critical extent is defined as “the potential severity of future reactions.” This represents a clinical evaluation of the worst case scenario for a future reaction. It can be based on the severity of past reactions, the dose and manner of exposure which caused reactions in the past, and the life-threatening potential of the type of reaction. Critical extent is a property of the allergy, and not of the reaction itself.",
        "comment": "The default criticality value for any propensity to an adverse reaction should be 'Low Risk', indicating at the very least a relative contraindication to deliberate or voluntary exposure to the substance. 'High Risk' is flagged if the clinician has identified a propensity for a more serious or potentially life-threatening reaction, such as anaphylaxis, and implies an absolute contraindication to deliberate or voluntary exposure to the substance. If this element is missing, the criticality is unknown (though it may be known elsewhere).\n\nSystems that capture a severity at the condition level are actually representing the concept of criticality whereas the severity documented at the reaction level is representing the true reaction severity.  Existing systems that are capturing both condition criticality and reaction severity may use the term \"severity\" to represent both.  Criticality is the worst it could be in the future (i.e. situation-agnostic) whereas severity is situation-dependent.",
        "alias": [
          "Severity",
          "Seriousness",
          "Contra-indication",
          "Risk",
          "MateVanKritiekZijn"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.criticality",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceCriticality"
            }
          ],
          "strength": "required",
          "description": "Use ConceptMap CriticalExtentCodelist_to_AllergyIntoleranceCriticality to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceCriticality",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/CriticalExtent-to-AllergyIntoleranceCriticality"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "AL1-4"
          },
          {
            "identity": "rim",
            "map": "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
          },
          {
            "identity": "w5",
            "map": "grade"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.7",
            "comment": "Criticality"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Criticality"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.id",
        "path": "AllergyIntolerance.criticality.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "xml:id (or equivalent in JSON)",
        "definition": "unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension",
        "path": "AllergyIntolerance.criticality.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist",
        "path": "AllergyIntolerance.criticality.extension",
        "sliceName": "criticalExtentCodelist",
        "short": "Optional Extensions Element",
        "definition": "Optional Extension Element - found in all resources.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://fhir.healthdata.be/StructureDefinition/ext-CodeSpecification"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist.id",
        "path": "AllergyIntolerance.criticality.extension.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "xml:id (or equivalent in JSON)",
        "definition": "unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist.extension",
        "path": "AllergyIntolerance.criticality.extension.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist.url",
        "path": "AllergyIntolerance.criticality.extension.url",
        "representation": [
          "xmlAttr"
        ],
        "short": "identifies the meaning of the extension",
        "definition": "Source of the definition for the extension code - a logical name or a URL.",
        "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
        "min": 1,
        "max": "1",
        "base": {
          "path": "Extension.url",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "uri"
          }
        ],
        "fixedUri": "https://fhir.healthdata.be/StructureDefinition/ext-CodeSpecification",
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist.value[x]",
        "path": "AllergyIntolerance.criticality.extension.value[x]",
        "short": "Criticality",
        "definition": "Critical extent is defined as “the potential severity of future reactions.” This represents a clinical evaluation of the worst case scenario for a future reaction. It can be based on the severity of past reactions, the dose and manner of exposure which caused reactions in the past, and the life-threatening potential of the type of reaction. Critical extent is a property of the allergy, and not of the reaction itself.",
        "alias": [
          "MateVanKritiekZijn"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "Extension.value[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/CriticalExtent"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.7",
            "comment": "Criticality"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Criticality"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.value",
        "path": "AllergyIntolerance.criticality.value",
        "representation": [
          "xmlAttr"
        ],
        "short": "Primitive value for code",
        "definition": "Primitive value for code",
        "min": 0,
        "max": "1",
        "base": {
          "path": "string.value",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-regex",
                "valueString": "[^\\s]+([\\s]?[^\\s]+)*"
              }
            ],
            "_code": {
              "extension": [
                {
                  "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-json-type",
                  "valueString": "string"
                },
                {
                  "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-xml-type",
                  "valueString": "xsd:token"
                },
                {
                  "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-rdf-type",
                  "valueString": "xsd:token"
                }
              ]
            }
          }
        ],
        "maxLength": 1048576
      },
      {
        "id": "AllergyIntolerance.code",
        "path": "AllergyIntolerance.code",
        "short": "CausativeAgent",
        "definition": "Substance, group of substances or environmental factor to which the patient is allergic or hypersensitive.",
        "comment": "It is strongly recommended that this element be populated using a terminology, where possible. For example, some terminologies used include RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10, UNI, ATC and CPT. Plain text should only be used if there is no appropriate terminology available. Additional details can be specified in the text.\r\rWhen a substance or product code is specified for the 'code' element, the \"default\" semantic context is that this is a positive statement of an allergy or intolerance (depending on the value of the 'type' element, if present) condition to the specified substance/product.  In the corresponding SNOMED CT allergy model, the specified substance/product is the target (destination) of the \"Causative agent\" relationship.\r\rThe 'substanceExposureRisk' extension is available as a structured and more flexible alternative to the 'code' element for making positive or negative allergy or intolerance statements.  This extension provides the capability to make \"no known allergy\" (or \"no risk of adverse reaction\") statements regarding any coded substance/product (including cases when a pre-coordinated \"no allergy to x\" concept for that substance/product does not exist).  If the 'substanceExposureRisk' extension is present, the AllergyIntolerance.code element SHALL be omitted.",
        "alias": [
          "Code",
          "VeroorzakendeStof"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.code",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceCode"
            }
          ],
          "strength": "required",
          "description": "Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.",
          "valueSet": "https://fhir.healthdata.be/ValueSet/CausativeAgent"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "AL1-3 / IAM-3"
          },
          {
            "identity": "rim",
            "map": "substance/product:\r\r.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rnegated/excluded substance/product:\r\r.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rpositive or negated/excluded condition/situation:\r\rObservation.code=ASSERTION; Observation.value"
          },
          {
            "identity": "w5",
            "map": "what"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.2",
            "comment": "CausativeAgent"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.CausativeAgent"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.patient",
        "path": "AllergyIntolerance.patient",
        "short": "Who the sensitivity is for",
        "definition": "The patient who has the allergy or intolerance.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "alias": [
          "Patient"
        ],
        "min": 1,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.patient",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %resource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "v2",
            "map": "(PID-3)"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=SBJ].role[classCode=PAT]"
          },
          {
            "identity": "w5",
            "map": "who.focus"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.onset[x]",
        "path": "AllergyIntolerance.onset[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        },
        "short": "When allergy or intolerance was identified",
        "definition": "Estimated or actual date,  date-time, or age when allergy or intolerance was identified.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.onset[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          },
          {
            "code": "Age"
          },
          {
            "code": "Period"
          },
          {
            "code": "Range"
          },
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "effectiveTime.low"
          },
          {
            "identity": "w5",
            "map": "when.init"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.onset[x]:onsetDateTime",
        "path": "AllergyIntolerance.onset[x]",
        "sliceName": "onsetDateTime",
        "short": "StartDateTime",
        "definition": "The date and time at which the allergy or undesired reaction was determined. This can be an exact date and time, or a rough indication of the date (such as only the year, or the month and the year).",
        "alias": [
          "BeginDatumTijd"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.onset[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "effectiveTime.low"
          },
          {
            "identity": "w5",
            "map": "when.init"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.6",
            "comment": "StartDateTime"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.StartDateTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.assertedDate",
        "path": "AllergyIntolerance.assertedDate",
        "short": "Date record was believed accurate",
        "definition": "The date on which the existance of the AllergyIntolerance was first asserted or acknowledged.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.assertedDate",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "IAM-20"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT].time"
          },
          {
            "identity": "w5",
            "map": "when.recorded"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.recorder",
        "path": "AllergyIntolerance.recorder",
        "short": "Who recorded the sensitivity",
        "definition": "Individual who recorded the record and takes responsibility for its content.",
        "comment": "References SHALL be a reference to an actual FHIR resource, and SHALL be resolveable (allowing for access control, temporary unavailability, etc). Resolution can be either by retrieval from the URL, or, where applicable by resource type, by treating an absolute reference as a canonical URL and looking it up in a local registry/repository.",
        "alias": [
          "Author"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.recorder",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Practitioner"
            ]
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %resource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=AUT].role"
          },
          {
            "identity": "w5",
            "map": "who.author"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.asserter",
        "path": "AllergyIntolerance.asserter",
        "short": "Source of the information about the allergy",
        "definition": "The source of the information about the allergy that is recorded.",
        "comment": "The recorder takes repsonsibility for the content, but can reference the source from where they got it.",
        "alias": [
          "Source",
          "Informant"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.asserter",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient"
            ]
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/RelatedPerson"
            ]
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Practitioner"
            ]
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ref-1",
            "severity": "error",
            "human": "SHALL have a contained resource if a local reference is provided",
            "expression": "reference.startsWith('#').not() or (reference.substring(1).trace('url') in %resource.contained.id.trace('ids'))",
            "xpath": "not(starts-with(f:reference/@value, '#')) or exists(ancestor::*[self::f:entry or self::f:parameter]/f:resource/f:*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')]|/*/f:contained/f:*[f:id/@value=substring-after(current()/f:reference/@value, '#')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Reference"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "The target of a resource reference is a RIM entry point (Act, Role, or Entity)"
          },
          {
            "identity": "v2",
            "map": "IAM-14 (if patient) / IAM-18 (if practitioner)"
          },
          {
            "identity": "rim",
            "map": ".participation[typeCode=INF].role"
          },
          {
            "identity": "w5",
            "map": "who.source"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.lastOccurrence",
        "path": "AllergyIntolerance.lastOccurrence",
        "short": "LastReactionDateTime",
        "definition": "Entry of the last time a hypersensitive reaction took place.",
        "comment": "This date may be replicated by one of the Onset of Reaction dates. Where a textual representation of the date of last occurrence is required e.g. 'In Childhood, '10 years ago' the Comment element should be used.",
        "alias": [
          "LaatsteReactieDatumTijd"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.lastOccurrence",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)].effectiveTime"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.8",
            "comment": "LastReactionDateTime"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.LastReactionDateTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note",
        "path": "AllergyIntolerance.note",
        "short": "Additional text not captured in other fields",
        "definition": "Additional narrative about the propensity for the Adverse Reaction, not captured in other fields.",
        "comment": "For example: including reason for flagging a seriousness of 'High Risk'; and instructions related to future exposure or administration of the substance, such as administration within an Intensive Care Unit or under corticosteroid cover. The notes should be related to an allergy or intolerance as a condition in general and not related to any particular episode of it. For episode notes and descriptions, use AllergyIntolerance.event.description and  AllergyIntolerance.event.notes.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.note",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act"
          },
          {
            "identity": "rim",
            "map": "subjectOf.observationEvent[code=\"annotation\"].value"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note.id",
        "path": "AllergyIntolerance.note.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "xml:id (or equivalent in JSON)",
        "definition": "unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note.extension",
        "path": "AllergyIntolerance.note.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note.author[x]",
        "path": "AllergyIntolerance.note.author[x]",
        "short": "Individual responsible for the annotation",
        "definition": "The individual responsible for making the annotation.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Annotation.author[x]",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Practitioner"
            ]
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/Patient"
            ]
          },
          {
            "code": "Reference",
            "targetProfile": [
              "http://hl7.org/fhir/StructureDefinition/RelatedPerson"
            ]
          },
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act.participant[typeCode=AUT].role"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note.time",
        "path": "AllergyIntolerance.note.time",
        "short": "When the annotation was made",
        "definition": "Indicates when this particular annotation was made.",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Annotation.time",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act.effectiveTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note.text",
        "path": "AllergyIntolerance.note.text",
        "short": "Comment",
        "definition": "Textual explanation of the hypersensitivity which cannot be entered in any of the other fields.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "alias": [
          "Toelichting"
        ],
        "min": 1,
        "max": "1",
        "base": {
          "path": "Annotation.text",
          "min": 1,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act.text"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.9",
            "comment": "Comment"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Comment"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction",
        "path": "AllergyIntolerance.reaction",
        "short": "Reaction",
        "definition": "Details about each adverse reaction event linked to exposure to the identified substance.",
        "alias": [
          "Reactie"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "BackboneElement"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)]"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.10",
            "comment": "Reaction"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.id",
        "path": "AllergyIntolerance.reaction.id",
        "representation": [
          "xmlAttr"
        ],
        "short": "xml:id (or equivalent in JSON)",
        "definition": "unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "comment": "Note that FHIR strings may not exceed 1MB in size",
        "min": 0,
        "max": "1",
        "base": {
          "path": "Element.id",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.extension",
        "path": "AllergyIntolerance.reaction.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "description": "Extensions are always sliced by (at least) url",
          "rules": "open"
        },
        "short": "Additional Content defined by implementations",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "Element.extension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.modifierExtension",
        "path": "AllergyIntolerance.reaction.modifierExtension",
        "short": "Extensions that cannot be ignored",
        "definition": "May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.",
        "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias": [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min": 0,
        "max": "*",
        "base": {
          "path": "BackboneElement.modifierExtension",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Extension"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          },
          {
            "key": "ext-1",
            "severity": "error",
            "human": "Must have either extensions or value[x], not both",
            "expression": "extension.exists() != value.exists()",
            "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
            "source": "http://hl7.org/fhir/StructureDefinition/Extension"
          }
        ],
        "isModifier": true,
        "isSummary": true,
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "N/A"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.substance",
        "path": "AllergyIntolerance.reaction.substance",
        "short": "SpecificSubstance",
        "definition": "More specific indication of the substance that caused the reaction. This can be a specific substance from a group of substances to which the patient is allergic or hypersensitive.",
        "comment": "Coding of the specific substance (or pharmaceutical product) with a terminology capable of triggering decision support should be used wherever possible.  The 'code' element allows for the use of a specific substance or pharmaceutical product, or a group or class of substances. In the case of an allergy or intolerance to a class of substances, (for example, \"penicillins\"), the 'reaction.substance' element could be used to code the specific substance that was identifed as having caused the reaction (for example, \"amoxycillin\"). Duplication of the value in the 'code' and 'reaction.substance' elements is acceptable when a specific substance has been recorded in 'code'.",
        "alias": [
          "SpecifiekeStof"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.substance",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "SubstanceCode"
            }
          ],
          "strength": "required",
          "description": "Codes defining the type of the substance (including pharmaceutical products).",
          "valueSet": "https://fhir.healthdata.be/ValueSet/CausativeAgent"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].participation[typeCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.12",
            "comment": "SpecificSubstance"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.SpecificSubstance"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation",
        "path": "AllergyIntolerance.reaction.manifestation",
        "short": "Symptom",
        "definition": "The content specifications of the reaction that takes place when the patient is exposed to the causative substance.",
        "comment": "Manifestation can be expressed as a single word, phrase or brief description. For example: nausea, rash or no reaction. It is preferable that manifestation should be coded with a terminology, where possible. The values entered here may be used to display on an application screen as part of a list of adverse reactions, as recommended in the UK NHS CUI guidelines.  Terminologies commonly used include, but are not limited to, SNOMED CT or ICD10.",
        "alias": [
          "Symptoms",
          "Signs",
          "Symptoom"
        ],
        "min": 1,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction.manifestation",
          "min": 1,
          "max": "*"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "Manifestation"
            }
          ],
          "strength": "extensible",
          "description": "Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.",
          "valueSet": "https://fhir.healthdata.be/ValueSet/Symptom"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "v2",
            "map": "AL1-5"
          },
          {
            "identity": "rim",
            "map": "code"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.11",
            "comment": "Symptom"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.Symptom"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.description",
        "path": "AllergyIntolerance.reaction.description",
        "short": "ReactionDescription",
        "definition": "Textual description of the reaction as a whole.",
        "comment": "Use the description to provide any details of a particular event of the occurred reaction such as circumstances, reaction specifics, what happened before/after. Information, related to the event, but not describing a particular care should be captured in the comment field. For example: at the age of four, the patient was given penicillin for strep throat and subsequently developed severe hives.",
        "alias": [
          "Narrative",
          "Text",
          "ReactieBeschrijving"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.description",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "string"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "text"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.13",
            "comment": "ReactionDescription"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.ReactionDescription"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.onset",
        "path": "AllergyIntolerance.reaction.onset",
        "short": "ReactionTime",
        "definition": "Date and time at which the reaction took place. This may also be just the date or a partial date, in the event that the exact date is unknown.",
        "alias": [
          "ReactieTijdstip"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.onset",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "AL1-6"
          },
          {
            "identity": "rim",
            "map": "effectiveTime.low"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.17",
            "comment": "ReactionTime"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.ReactionTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.severity",
        "path": "AllergyIntolerance.reaction.severity",
        "short": "Severity",
        "definition": "The severity of the reaction as a result of exposure to the causative substance.",
        "comment": "It is acknowledged that this assessment is very subjective. There may be some some specific practice domains where objective scales have been applied. Objective scales can be included in this model as extensions.",
        "alias": [
          "Ernst"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.severity",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "code"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "AllergyIntoleranceSeverity"
            }
          ],
          "strength": "required",
          "description": "Use ConceptMap CriticalExtentCodelist_to_AllergyIntoleranceSeverity to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceSeverity",
          "valueSet": "http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/CriticalExtent-to-AllergyIntoleranceSeverity"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "rim",
            "map": "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.14",
            "comment": "Severity"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.Severity"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.exposureRoute",
        "path": "AllergyIntolerance.reaction.exposureRoute",
        "short": "RouteOfExposure",
        "definition": "Way in which the patient came into contact with the causative agent or the way in which the agent was administered.",
        "comment": "Coding of the route of exposure with a terminology should be used wherever possible.",
        "alias": [
          "WijzeVanBlootstelling"
        ],
        "min": 0,
        "max": "1",
        "base": {
          "path": "AllergyIntolerance.reaction.exposureRoute",
          "min": 0,
          "max": "1"
        },
        "type": [
          {
            "code": "CodeableConcept"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "binding": {
          "extension": [
            {
              "url": "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString": "RouteOfAdministration"
            }
          ],
          "strength": "required",
          "description": "A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.",
          "valueSet": "https://fhir.healthdata.be/ValueSet/RouteOfExposure"
        },
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "CE/CNE/CWE"
          },
          {
            "identity": "rim",
            "map": "CD"
          },
          {
            "identity": "orim",
            "map": "fhir:CodeableConcept rdfs:subClassOf dt:CD"
          },
          {
            "identity": "rim",
            "map": "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].routeCode"
          },
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.15",
            "comment": "RouteOfExposure"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.RouteOfExposure"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.note",
        "path": "AllergyIntolerance.reaction.note",
        "short": "Text about event not captured in other fields",
        "definition": "Additional text about the adverse reaction event not captured in other fields.",
        "comment": "Use this field to record information indirectly related to a particular event and not captured in the description. For example: Clinical records are no longer available, recorded based on information provided to the patient by her mother and her mother is deceased.",
        "min": 0,
        "max": "*",
        "base": {
          "path": "AllergyIntolerance.reaction.note",
          "min": 0,
          "max": "*"
        },
        "type": [
          {
            "code": "Annotation"
          }
        ],
        "condition": [
          "ele-1"
        ],
        "constraint": [
          {
            "key": "ele-1",
            "severity": "error",
            "human": "All FHIR elements must have a @value or children",
            "expression": "hasValue() | (children().count() > id.count())",
            "xpath": "@value|f:*|h:div",
            "source": "http://hl7.org/fhir/StructureDefinition/Element"
          }
        ],
        "mapping": [
          {
            "identity": "rim",
            "map": "n/a"
          },
          {
            "identity": "v2",
            "map": "N/A"
          },
          {
            "identity": "rim",
            "map": "Act"
          },
          {
            "identity": "rim",
            "map": "subjectOf.observationEvent[code=\"annotation\"].value"
          }
        ]
      }
    ]
  },
  "differential": {
    "element": [
      {
        "id": "AllergyIntolerance",
        "path": "AllergyIntolerance",
        "short": "AllergyIntolerance",
        "alias": [
          "AllergieIntolerantie"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.1",
            "comment": "AllergyIntolerance"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.clinicalStatus",
        "path": "AllergyIntolerance.clinicalStatus",
        "short": "AllergyStatus",
        "definition": "Statement on the status of the patient’s hypersensitivity.",
        "comment": "See the comment on the root element for guidance on mapping zib AllergyStatus to FHIR.",
        "alias": [
          "AllergieStatus"
        ],
        "binding": {
          "strength": "required",
          "description": "Use ConceptMap AllergyStatusCodelist_to_AllergyIntoleranceClinicalStatusCodes to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceClinicalStatusCodes",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/AllergyStatus-to-AllergyIntoleranceClinicalStatusCodes"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.5",
            "comment": "AllergyStatus"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.AllergyStatus"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.verificationStatus",
        "path": "AllergyIntolerance.verificationStatus",
        "short": "AllergyStatus",
        "alias": [
          "AllergieStatus"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.5",
            "comment": "AllergyStatus"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category",
        "path": "AllergyIntolerance.category",
        "short": "AllergyCategory",
        "definition": "Identifies the allergy category such as medication, food or environment.",
        "alias": [
          "AllergieCategorie"
        ],
        "max": "1",
        "binding": {
          "strength": "required",
          "description": "Use ConceptMap AllergyCategoryCodelist_to_AllergyIntoleranceCategory to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceCategory",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/AllergyCategory-to-AllergyIntoleranceCategory"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.4",
            "comment": "AllergyCategory"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.AllergyCategory"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension",
        "path": "AllergyIntolerance.category.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "rules": "open"
        },
        "min": 0
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist",
        "path": "AllergyIntolerance.category.extension",
        "sliceName": "allergyCategoryCodelist",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://fhir.healthdata.be/StructureDefinition/ext-CodeSpecification"
            ]
          }
        ]
      },
      {
        "id": "AllergyIntolerance.category.extension:allergyCategoryCodelist.value[x]",
        "path": "AllergyIntolerance.category.extension.value[x]",
        "short": "AllergyCategory",
        "definition": "Identifies the allergy category such as medication, food or environment.",
        "alias": [
          "AllergieCategorie"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/AllergyCategory"
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.4",
            "comment": "AllergyCategory"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.AllergyCategory"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality",
        "path": "AllergyIntolerance.criticality",
        "short": "Criticality",
        "definition": "Critical extent is defined as “the potential severity of future reactions.” This represents a clinical evaluation of the worst case scenario for a future reaction. It can be based on the severity of past reactions, the dose and manner of exposure which caused reactions in the past, and the life-threatening potential of the type of reaction. Critical extent is a property of the allergy, and not of the reaction itself.",
        "alias": [
          "MateVanKritiekZijn"
        ],
        "binding": {
          "strength": "required",
          "description": "Use ConceptMap CriticalExtentCodelist_to_AllergyIntoleranceCriticality to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceCriticality",
          "valueSet": "http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/CriticalExtent-to-AllergyIntoleranceCriticality"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.7",
            "comment": "Criticality"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Criticality"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension",
        "path": "AllergyIntolerance.criticality.extension",
        "slicing": {
          "discriminator": [
            {
              "type": "value",
              "path": "url"
            }
          ],
          "rules": "open"
        },
        "min": 0
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist",
        "path": "AllergyIntolerance.criticality.extension",
        "sliceName": "criticalExtentCodelist",
        "min": 0,
        "max": "1",
        "type": [
          {
            "code": "Extension",
            "profile": [
              "https://fhir.healthdata.be/StructureDefinition/ext-CodeSpecification"
            ]
          }
        ]
      },
      {
        "id": "AllergyIntolerance.criticality.extension:criticalExtentCodelist.value[x]",
        "path": "AllergyIntolerance.criticality.extension.value[x]",
        "short": "Criticality",
        "definition": "Critical extent is defined as “the potential severity of future reactions.” This represents a clinical evaluation of the worst case scenario for a future reaction. It can be based on the severity of past reactions, the dose and manner of exposure which caused reactions in the past, and the life-threatening potential of the type of reaction. Critical extent is a property of the allergy, and not of the reaction itself.",
        "alias": [
          "MateVanKritiekZijn"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/CriticalExtent"
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.7",
            "comment": "Criticality"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Criticality"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.code",
        "path": "AllergyIntolerance.code",
        "short": "CausativeAgent",
        "definition": "Substance, group of substances or environmental factor to which the patient is allergic or hypersensitive.",
        "alias": [
          "VeroorzakendeStof"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/CausativeAgent"
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.2",
            "comment": "CausativeAgent"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.CausativeAgent"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.onset[x]",
        "path": "AllergyIntolerance.onset[x]",
        "slicing": {
          "discriminator": [
            {
              "type": "type",
              "path": "$this"
            }
          ],
          "rules": "open"
        }
      },
      {
        "id": "AllergyIntolerance.onset[x]:onsetDateTime",
        "path": "AllergyIntolerance.onset[x]",
        "sliceName": "onsetDateTime",
        "short": "StartDateTime",
        "definition": "The date and time at which the allergy or undesired reaction was determined. This can be an exact date and time, or a rough indication of the date (such as only the year, or the month and the year).",
        "alias": [
          "BeginDatumTijd"
        ],
        "type": [
          {
            "code": "dateTime"
          }
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.6",
            "comment": "StartDateTime"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.StartDateTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.lastOccurrence",
        "path": "AllergyIntolerance.lastOccurrence",
        "short": "LastReactionDateTime",
        "definition": "Entry of the last time a hypersensitive reaction took place.",
        "alias": [
          "LaatsteReactieDatumTijd"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.8",
            "comment": "LastReactionDateTime"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.LastReactionDateTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.note",
        "path": "AllergyIntolerance.note",
        "max": "1"
      },
      {
        "id": "AllergyIntolerance.note.text",
        "path": "AllergyIntolerance.note.text",
        "short": "Comment",
        "definition": "Textual explanation of the hypersensitivity which cannot be entered in any of the other fields.",
        "alias": [
          "Toelichting"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.9",
            "comment": "Comment"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Comment"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction",
        "path": "AllergyIntolerance.reaction",
        "short": "Reaction",
        "alias": [
          "Reactie"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.10",
            "comment": "Reaction"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.substance",
        "path": "AllergyIntolerance.reaction.substance",
        "short": "SpecificSubstance",
        "definition": "More specific indication of the substance that caused the reaction. This can be a specific substance from a group of substances to which the patient is allergic or hypersensitive.",
        "alias": [
          "SpecifiekeStof"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/CausativeAgent"
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.12",
            "comment": "SpecificSubstance"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.SpecificSubstance"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.manifestation",
        "path": "AllergyIntolerance.reaction.manifestation",
        "short": "Symptom",
        "definition": "The content specifications of the reaction that takes place when the patient is exposed to the causative substance.",
        "alias": [
          "Symptoom"
        ],
        "binding": {
          "strength": "extensible",
          "valueSet": "https://fhir.healthdata.be/ValueSet/Symptom"
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.11",
            "comment": "Symptom"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.Symptom"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.description",
        "path": "AllergyIntolerance.reaction.description",
        "short": "ReactionDescription",
        "definition": "Textual description of the reaction as a whole.",
        "alias": [
          "ReactieBeschrijving"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.13",
            "comment": "ReactionDescription"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.ReactionDescription"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.onset",
        "path": "AllergyIntolerance.reaction.onset",
        "short": "ReactionTime",
        "definition": "Date and time at which the reaction took place. This may also be just the date or a partial date, in the event that the exact date is unknown.",
        "alias": [
          "ReactieTijdstip"
        ],
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.17",
            "comment": "ReactionTime"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.ReactionTime"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.severity",
        "path": "AllergyIntolerance.reaction.severity",
        "short": "Severity",
        "definition": "The severity of the reaction as a result of exposure to the causative substance.",
        "alias": [
          "Ernst"
        ],
        "binding": {
          "strength": "required",
          "description": "Use ConceptMap CriticalExtentCodelist_to_AllergyIntoleranceSeverity to translate terminology from the functional model to profile terminology in ValueSet AllergyIntoleranceSeverity",
          "valueSet": "http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1",
          "_valueSet": {
            "extension": [
              {
                "url": "http://hl7.org/fhir/StructureDefinition/11179-permitted-value-conceptmap",
                "valueCanonical": "https://fhir.healthdata.be/ConceptMap/CriticalExtent-to-AllergyIntoleranceSeverity"
              }
            ]
          }
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.14",
            "comment": "Severity"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.Severity"
          }
        ]
      },
      {
        "id": "AllergyIntolerance.reaction.exposureRoute",
        "path": "AllergyIntolerance.reaction.exposureRoute",
        "short": "RouteOfExposure",
        "definition": "Way in which the patient came into contact with the causative agent or the way in which the agent was administered.",
        "alias": [
          "WijzeVanBlootstelling"
        ],
        "binding": {
          "strength": "required",
          "valueSet": "https://fhir.healthdata.be/ValueSet/RouteOfExposure"
        },
        "mapping": [
          {
            "identity": "zib-allergyintolerance-v3.3-2020EN",
            "map": "NL-CM:8.2.15",
            "comment": "RouteOfExposure"
          },
          {
            "identity": "HdBe-AllergyIntolerance",
            "map": "AllergyIntolerance.Reaction.RouteOfExposure"
          }
        ]
      }
    ]
  }
}